Conditional modulation of glucocorticoid receptor activities by CREB-binding protein (CBP) and p300

Journal of Steroid Biochemistry and Molecular Biology

Volumn 70, Issue 1-3, 1999, Pages 15-25

  Kino, Tomoshige ^a   Nordeen, Steven K ^b   Chrousos, George P ^a  

^a Section on Pediatric Endocrinology   (United States)

^b UNIVERSITY OF COLORADO   (United States)

Author keywords

Coactivator; CREB; Mouse mammary tumor virus (MMTV); p300; SRC 1

Indexed keywords

CELL NUCLEUS RECEPTOR; GLUCOCORTICOID; GLUCOCORTICOID RECEPTOR; GLUCOCORTICOID RECEPTOR ANTAGONIST;

ARTICLE; CONTROLLED STUDY; EXPRESSION VECTOR; HORMONE ACTION; HUMAN; HUMAN CELL; MOUSE MAMMARY TUMOR ONCOVIRUS; RECEPTOR BINDING; SIGNAL TRANSDUCTION;

ANIMALS; BETA-GALACTOSIDASE; CHLORAMPHENICOL O-ACETYLTRANSFERASE; CREB-BINDING PROTEIN; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; E1A-ASSOCIATED P300 PROTEIN; HELA CELLS; HUMANS; LUCIFERASES; MAMMARY TUMOR VIRUS, MOUSE; MICE; NUCLEAR PROTEINS; PROMOTER REGIONS (GENETICS); RECEPTORS, GLUCOCORTICOID; TRANS-ACTIVATORS;

EID: 0032865411     PISSN: 09600760     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-0760(99)00100-4     Document Type: Article

References (41)

1. Bamberger C.M., Schulte H.M., Chrousos G.P. Molecular determinants of glucocorticoid receptor function and tissue sensitivity to glucocorticoids. Endocr. Rev. 17:1996;245-261.
2. Beato M., Sanchez-Pacheco A. Interaction of steroid hormone receptors with the transcription initiation complex. Endocr. Rev. 17:1996;587-609.
3. Ogryzko V.V., Schiltz R.L., Russanova V., Howard B.H., Nakatani Y. The transcriptional coactivators p300 and CBP are histone acetyltransferases. Cell. 87:1996;953-959.
4. Spencer T.E., Jenster G., Burcin M.M., Allis C.D., Zhou J., Mizzen C.A., McKenna N.J., Onate S.A., Tsai S.Y., Tsai M.J., O'Malley B.W. Steroid receptor coactivator-1 is a histone acetyltransferase. Nature. 389:1997;194-198.
5. Kwok R.P., Lundblad J.R., Chrivia J.C., Richards J.P., Bachinger H.P., Brennan R.G., Roberts S.G., Green M.R., Goodman R.H. Nuclear protein CBP is a coactivator for the transcription factor CREB. Nature. 370:1994;223-226.
6. Chrivia J.C., Kwok R.P., Lamb N., Hagiwara M., Montminy M.R., Goodman R.H. Phosphorylated CREB binds specifically to the nuclear protein CBP. Nature. 365:1993;855-859.
7. Eckner R., Ewen M.E., Newsome D., Gerdes M., DeCaprio J.A., Lawrence J.B., Livingston D.M. Molecular cloning and functional analysis of the adenovirus E1A- associated 300-kD protein (p300) reveals a protein with properties of a transcriptional adaptor. Genes Dev. 8:1994;869-884.
8. Lundblad J.R., Kwok R.P., Laurance M.E., Harter M.L., Goodman R.H. Adenoviral E1A-associated protein p300 as a functional homologue of the transcriptional co-activator CBP. Nature. 374:1995;85-88.
9. Kamei Y., Xu L., Heinzel T., Torchia J., Kurokawa R., Gloss B., Lin S.C., Heyman R.A., Rose D.W., Glass C.K., Rosenfeld M.G. A CBP integrator complex mediates transcriptional activation and AP-1 inhibition by nuclear receptors. Cell. 85:1996;403-414.
10. Perkins N.D., Felzien L.K., Betts J.C., Leung K., Beach D.H., Nabel G.J. Regulation of NF-kappaB by cyclin-dependent kinases associated with the p300 coactivator. Science. 275:1997;523-527.
11. Lill N.L., Grossman S.R., Ginsberg D., DeCaprio J., Livingston D.M. Binding and modulation of p53 by p300/CBP coactivators. Nature. 387:1997;823-827.
12. Gu W., Shi X.L., Roeder R.G. Synergistic activation of transcription by CBP and p53. Nature. 387:1997;819-823.
13. Avantaggiati M.L., Ogryzko V., Gardner K., Giordano A., Levine A.S., Kelly K. Recruitment of p300/CBP in p53-dependent signal pathways. Cell. 89:1997;1175-1184.
14. Bhattacharya S., Eckner R., Grossman S., Oldread E., Arany Z., D'Andrea A., Livingston D.M. Cooperation of Stat2 and p300/CBP in signalling induced by interferon-alpha. Nature. 383:1996;344-347.
15. Zhang J.J., Vinkemeier U., Gu W., Chakravarti D., Horvath C.M., Darnell J.E. Jr. Two contact regions between Stat1 and CBP/p300 in interferon gamma signaling. Proc. Natl Acad. Sci. USA. 93:1996;15092-15096.
16. Horvai A.E., Xu L., Korzus E., Brard G., Kalafus D., Mullen T.M., Rose D.W., Rosenfeld M.G., Glass C.K. Nuclear integration of JAK/STAT and Ras/AP-1 signaling by CBP and p300. Proc. Natl Acad. Sci. USA. 94:1997;1074-1079.
17. Aarnisalo P., Palvimo J.J., Janne O.A. CREB-binding protein in androgen receptor-mediated signaling. Proc. Natl Acad. Sci. USA. 95:1998;2122-2127.
18. Dowell P., Ishmael J.E., Avram D., Peterson V.J., Nevrivy D.J., Leid M. p300 functions as a coactivator for the peroxisome proliferator-activated receptor alpha. J. Biol. Chem. 272:1997;33,435-33,443.
19. Chakravarti D., LaMorte V.J., Nelson M.C., Nakajima T., Schulman I.G., Juguilon H., Montminy M., Evans R.M. Role of CBP/P300 in nuclear receptor signalling. Nature. 383:1996;99-103.
20. Nakajima T., Fukamizu A., Takahashi J., Gage F.H., Fisher T., Blenis J., Montminy M.R. The signal-dependent coactivator CBP is a nuclear target for pp90RSK. Cell. 86:1996;465-474.
21. Torchia J., Rose D.W., Inostroza J., Kamei Y., Westin S., Glass C.K., Rosenfeld M.G. The transcriptional co-activator p/CIP binds CBP and mediates nuclear-receptor function. Nature. 387:1997;677-684.
22. Onate S.A., Tsai S.Y., Tsai M.J., O'Malley B.W. Sequence and characterization of a coactivator for the steroid hormone receptor superfamily. Science. 270:1995;1354-1357.
23. Hong H., Kohli K., Trivedi A., Johnson D.L., Stallcup M.R. GRIP1, a novel mouse protein that serves as a transcriptional coactivator in yeast for the hormone binding domains of steroid receptors. Proc. Natl Acad. Sci. USA. 93:1996;4948-4952.
24. Chen H., Lin R.J., Schiltz R.L., Chakravarti D., Nash A., Nagy L., Privalsky M.L., Nakatani Y., Evans R.M. Nuclear receptor coactivator ACTR is a novel histone acetyltransferase and forms a multimeric activation complex with P/CAF and CBP/p300. Cell. 90:1997;569-580.
25. Heery D.M., Kalkhoven E., Hoare S., Parker M.G. A signature motif in transcriptional co-activators mediates binding to nuclear receptors. Nature. 387:1997;733-736.
26. Chrousos G.P. The hypothalamic-pituitary-adrenal axis and immune-mediated inflammation. N. Engl. J. Med. 332:1995;1351-1362.
27. Chrousos G.P., Castro M., Leung D.Y., Webster E., Kino T., Bamberger C., Elliot S., Stratakis C., Karl M. Molecular mechanisms of glucocorticoid resistance/hypersensitivity. Potential clinical implications. Am. J. Respir. Crit. Care Med. 154:1996;S39-S43.
28. Bresnick E.H., John S., Berard D.S., LeFebvre P., Hager G.L. Glucocorticoid receptor-dependent disruption of a specific nucleosome on the mouse mammary tumor virus promoter is prevented by sodium butyrate. Proc. Natl Acad. Sci. USA. 87:1990;3977-3981.
29. Guido E.C., Delorme E.O., Clemm D.L., Stein R.B., Rosen J., Miner J.N. Determinants of promoter-specific activity by glucocorticoid receptor. Mol. Endocrinol. 10:1996;1178-1190.
30. Nordeen S.K., Ogden C.A., Taraseviciene L., Lieberman B.A. Extreme position dependence of a canonical hormone response element. Mol. Endocrinol. 12:1998;891-898.
31. de Castro M., Elliot S., Kino T., Bamberger C., Karl M., Webster E., Chrousos G.P. The non-ligand binding beta-isoform of the human glucocorticoid receptor (hGR beta): tissue levels, mechanism of action, and potential physiologic role. Mol. Med. 2:1996;597-607.
32. Karl M., Lamberts S.W., Koper J.W., Katz D.A., Huizenga N.E., Kino T., Haddad B.R., Hughes M.R., Chrousos G.P. Cushing's disease preceded by generalized glucocorticoid resistance: clinical consequences of a novel, dominant-negative glucocorticoid receptor mutation. Proc. Assoc. Am. Physicians. 108:1996;296-307.
33. Smith C.L., Onate S.A., Tsai M.J., O'Malley B.W. CREB binding protein acts synergistically with steroid receptor coactivator-1 to enhance steroid receptor-dependent transcription. Proc. Natl Acad. Sci. USA. 93:1996;8884-8888.
34. Yao T., Fuchs M., Zhou N., Ch'ng L., Newsome D., Li E., Livingston D.M., Eckner R. Gene dosage-dependent embryonic development and proliferation defects in mice lacking the transcriptional integrator p300. Cell. 93:1998;361-372.
35. Feng W., Ribeiro R.C.J., Wagner R.L., Nguyen H., Apriletti J.W., Fletterick R.J., Baxter J.D., Kushner P.J., West B.L. Hormone-dependent coactivator binding to a hydrophobic cleft on nuclear receptors. Science. 280:1998;1747-1749.
36. Yang X.J., Ogryzko V.V., Nishikawa J., Howard B.H., Nakatani Y. A p300/CBP-associated factor that competes with the adenoviral oncoprotein E1A. Nature. 382:1996;319-324.
37. Treuter E., Albrektsen T., Johansson L., Leers J., Gustafsson J.A. A regulatory role for RIP140 in nuclear receptor activation. Mol. Endocrinol. 12:1998;864-881.
38. Dallas P.B., Yaciuk P., Moran E. Characterization of monoclonal antibodies raised against p300: both p300 and CBP are present in intracellular TBP complexes. J. Virol. 71:1997;1726-1731.
39. Waltzer L., Bienz M. Drosophila CBP represses the transcription factor TCF to antagonize Wingless signalling. Nature. 395:1998;521-525.
40. Yuan W., Condorelli G., Caruso M., Felsani A., Giordano A. Human p300 protein is a coactivator for the transcription factor MyoD. J. Biol. Chem. 271:1996;9009-9013.
41. Eckner R. p300 and CBP as transcriptional regulators and targets of oncogenic events. Biol. Chem. 377:1996;685-688.