-
1
-
-
0035412104
-
Pattern of malignant disorders in individuals with Down's syndrome
-
Hasle H. Pattern of malignant disorders in individuals with Down's syndrome. Lancet Oncol 2 (2001) 429-436
-
(2001)
Lancet Oncol
, vol.2
, pp. 429-436
-
-
Hasle, H.1
-
2
-
-
0036727413
-
Acquired mutations in GATA1 in the megakaryoblastic leukemia of Down syndrome
-
Wechsler J., Greene M., McDevitt M.A., et al. Acquired mutations in GATA1 in the megakaryoblastic leukemia of Down syndrome. Nat Genet 32 (2002) 148-152
-
(2002)
Nat Genet
, vol.32
, pp. 148-152
-
-
Wechsler, J.1
Greene, M.2
McDevitt, M.A.3
-
3
-
-
0042243593
-
Mutations in exon 2 of GATA1 are early events in megakaryocytic malignancies associated with trisomy 21
-
Rainis L., Bercovich D., Strehl S., et al. Mutations in exon 2 of GATA1 are early events in megakaryocytic malignancies associated with trisomy 21. Blood 102 (2003) 981-986
-
(2003)
Blood
, vol.102
, pp. 981-986
-
-
Rainis, L.1
Bercovich, D.2
Strehl, S.3
-
4
-
-
33750631224
-
Down myeloid disorders: a paradigm for childhood preleukaemia and leukaemia and insights into normal megakaryopoiesis
-
Vyas P., and Roberts I. Down myeloid disorders: a paradigm for childhood preleukaemia and leukaemia and insights into normal megakaryopoiesis. Early Hum Dev 82 (2006) 767-773
-
(2006)
Early Hum Dev
, vol.82
, pp. 767-773
-
-
Vyas, P.1
Roberts, I.2
-
5
-
-
0037906527
-
Acquired mutations in GATA1 in neonates with Down's syndrome with transient myeloid disorder
-
Groet J., McElwaine S., Spinelli M., et al. Acquired mutations in GATA1 in neonates with Down's syndrome with transient myeloid disorder. Lancet 361 (2003) 1617-1620
-
(2003)
Lancet
, vol.361
, pp. 1617-1620
-
-
Groet, J.1
McElwaine, S.2
Spinelli, M.3
-
6
-
-
0035473994
-
Childhood acute lymphoblastic leukaemia-current status and future perspectives
-
Pui C.H., Campana D., and Evans W.E. Childhood acute lymphoblastic leukaemia-current status and future perspectives. Lancet Oncol 2 (2001) 597-607
-
(2001)
Lancet Oncol
, vol.2
, pp. 597-607
-
-
Pui, C.H.1
Campana, D.2
Evans, W.E.3
-
7
-
-
28844446288
-
Clinical characteristics and outcome of children with Down syndrome and acute lymphoblastic leukemia: a Children's Cancer Group study
-
Whitlock J.A., Sather H.N., Gaynon P., et al. Clinical characteristics and outcome of children with Down syndrome and acute lymphoblastic leukemia: a Children's Cancer Group study. Blood 106 (2005) 4043-4049
-
(2005)
Blood
, vol.106
, pp. 4043-4049
-
-
Whitlock, J.A.1
Sather, H.N.2
Gaynon, P.3
-
8
-
-
38949098169
-
Cytogenetic features of acute lymphoblastic and myeloid leukemias in pediatric patients with Down syndrome-an iBFM-SG study
-
Forestier E., Izraeli S., Beverloo B., et al. Cytogenetic features of acute lymphoblastic and myeloid leukemias in pediatric patients with Down syndrome-an iBFM-SG study. Blood 111 (2008) 1575-1583
-
(2008)
Blood
, vol.111
, pp. 1575-1583
-
-
Forestier, E.1
Izraeli, S.2
Beverloo, B.3
-
9
-
-
33846660947
-
JAK2 exon 12 mutations in polycythemia vera and idiopathic erythrocytosis
-
Scott L.M., Tong W., Levine R.L., et al. JAK2 exon 12 mutations in polycythemia vera and idiopathic erythrocytosis. N Engl J Med 356 (2007) 459-468
-
(2007)
N Engl J Med
, vol.356
, pp. 459-468
-
-
Scott, L.M.1
Tong, W.2
Levine, R.L.3
-
10
-
-
33845436745
-
The myeloproliferative disorders
-
Campbell P.J., and Green A.R. The myeloproliferative disorders. N Engl J Med 355 (2006) 2452-2466
-
(2006)
N Engl J Med
, vol.355
, pp. 2452-2466
-
-
Campbell, P.J.1
Green, A.R.2
-
11
-
-
20244369569
-
Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis
-
Levine R.L., Wadleigh M., Cools J., et al. Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis. Cancer Cell 7 (2005) 387-397
-
(2005)
Cancer Cell
, vol.7
, pp. 387-397
-
-
Levine, R.L.1
Wadleigh, M.2
Cools, J.3
-
12
-
-
17644424955
-
A gain-of-function mutation of JAK2 in myeloproliferative disorders
-
Kralovics R., Passamonti F., Buser A.S., et al. A gain-of-function mutation of JAK2 in myeloproliferative disorders. N Engl J Med 352 (2005) 1779-1790
-
(2005)
N Engl J Med
, vol.352
, pp. 1779-1790
-
-
Kralovics, R.1
Passamonti, F.2
Buser, A.S.3
-
13
-
-
17844383458
-
A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera
-
James C., Ugo V., Le Couedic J.P., et al. A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera. Nature 434 (2005) 1144-1148
-
(2005)
Nature
, vol.434
, pp. 1144-1148
-
-
James, C.1
Ugo, V.2
Le Couedic, J.P.3
-
14
-
-
33745713168
-
Activating alleles of JAK3 in acute megakaryoblastic leukemia
-
Walters D.K., Mercher T., Gu T.L., et al. Activating alleles of JAK3 in acute megakaryoblastic leukemia. Cancer Cell 10 (2006) 65-75
-
(2006)
Cancer Cell
, vol.10
, pp. 65-75
-
-
Walters, D.K.1
Mercher, T.2
Gu, T.L.3
-
15
-
-
34547946210
-
Analysis of JAK3, JAK2, and C-MPL mutations in transient myeloproliferative disorder and myeloid leukemia of Down syndrome blasts in children with Down syndrome
-
Norton A., Fisher C., Liu H., et al. Analysis of JAK3, JAK2, and C-MPL mutations in transient myeloproliferative disorder and myeloid leukemia of Down syndrome blasts in children with Down syndrome. Blood 110 (2007) 1077-1079
-
(2007)
Blood
, vol.110
, pp. 1077-1079
-
-
Norton, A.1
Fisher, C.2
Liu, H.3
-
16
-
-
34548807675
-
Stat5 is essential for early B cell development but not for B cell maturation and function
-
Dai X., Chen Y., Di L., et al. Stat5 is essential for early B cell development but not for B cell maturation and function. J Immunol 179 (2007) 1068-1079
-
(2007)
J Immunol
, vol.179
, pp. 1068-1079
-
-
Dai, X.1
Chen, Y.2
Di, L.3
-
17
-
-
15444339209
-
A TEL-JAK2 fusion protein with constitutive kinase activity in human leukemia
-
Lacronique V., Boureux A., Valle V.D., et al. A TEL-JAK2 fusion protein with constitutive kinase activity in human leukemia. Science 278 (1997) 1309-1312
-
(1997)
Science
, vol.278
, pp. 1309-1312
-
-
Lacronique, V.1
Boureux, A.2
Valle, V.D.3
-
18
-
-
33847393317
-
Novel activating JAK2 mutation in a patient with Down syndrome and B-cell precursor acute lymphoblastic leukemia
-
Malinge S., Ben-Abdelali R., Settegrana C., et al. Novel activating JAK2 mutation in a patient with Down syndrome and B-cell precursor acute lymphoblastic leukemia. Blood 109 (2007) 2202-2224
-
(2007)
Blood
, vol.109
, pp. 2202-2224
-
-
Malinge, S.1
Ben-Abdelali, R.2
Settegrana, C.3
-
19
-
-
0242266952
-
Denaturing high-performance liquid chromatography for the detection of mutations and polymorphisms in UBE3A
-
Bercovich D., and Beaudet A.L. Denaturing high-performance liquid chromatography for the detection of mutations and polymorphisms in UBE3A. Genet Test 7 (2003) 189-194
-
(2003)
Genet Test
, vol.7
, pp. 189-194
-
-
Bercovich, D.1
Beaudet, A.L.2
-
20
-
-
0026063514
-
The cytoplasmic region of the erythropoietin receptor contains nonoverlapping positive and negative growth-regulatory domains
-
D'Andrea A.D., Yoshimura A., Youssoufian H., Zon L.I., Koo J.W., and Lodish H.F. The cytoplasmic region of the erythropoietin receptor contains nonoverlapping positive and negative growth-regulatory domains. Mol Cell Biol 11 (1991) 1980-1987
-
(1991)
Mol Cell Biol
, vol.11
, pp. 1980-1987
-
-
D'Andrea, A.D.1
Yoshimura, A.2
Youssoufian, H.3
Zon, L.I.4
Koo, J.W.5
Lodish, H.F.6
-
21
-
-
2542445427
-
ConSurf: identification of functional regions in proteins by surface-mapping of phylogenetic information
-
Glaser F., Pupko T., Paz I., et al. ConSurf: identification of functional regions in proteins by surface-mapping of phylogenetic information. Bioinformatics 19 (2003) 163-164
-
(2003)
Bioinformatics
, vol.19
, pp. 163-164
-
-
Glaser, F.1
Pupko, T.2
Paz, I.3
-
23
-
-
30044437118
-
Expression of a homodimeric type I cytokine receptor is required for JAK2V617F-mediated transformation
-
Lu X., Levine R., Tong W., et al. Expression of a homodimeric type I cytokine receptor is required for JAK2V617F-mediated transformation. Proc Natl Acad Sci USA 102 (2005) 18962-18967
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 18962-18967
-
-
Lu, X.1
Levine, R.2
Tong, W.3
-
25
-
-
34547203007
-
Trisomy of chromosome 21 in leukemogenesis
-
Izraeli S., Rainis L., Hertzberg L., Smooha G., and Birger Y. Trisomy of chromosome 21 in leukemogenesis. Blood Cells Mol Dis 39 (2007) 156-159
-
(2007)
Blood Cells Mol Dis
, vol.39
, pp. 156-159
-
-
Izraeli, S.1
Rainis, L.2
Hertzberg, L.3
Smooha, G.4
Birger, Y.5
-
26
-
-
0035979262
-
An inherited p53 mutation that contributes in a tissue-specific manner to pediatric adrenal cortical carcinoma
-
Ribeiro R.C., Sandrini F., Figueiredo B., et al. An inherited p53 mutation that contributes in a tissue-specific manner to pediatric adrenal cortical carcinoma. Proc Natl Acad Sci USA 98 (2001) 9330-9335
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 9330-9335
-
-
Ribeiro, R.C.1
Sandrini, F.2
Figueiredo, B.3
-
27
-
-
0036762867
-
Prediction of the structure of human Janus kinase 2 (JAK2) comprising JAK homology domains 1 through 7
-
Giordanetto F., and Kroemer R.T. Prediction of the structure of human Janus kinase 2 (JAK2) comprising JAK homology domains 1 through 7. Protein Eng 15 (2002) 727-737
-
(2002)
Protein Eng
, vol.15
, pp. 727-737
-
-
Giordanetto, F.1
Kroemer, R.T.2
-
28
-
-
38349053791
-
JAK2 inhibitor therapy in myeloproliferative disorders: rationale, preclinical studies and ongoing clinical trials
-
Pardanani A. JAK2 inhibitor therapy in myeloproliferative disorders: rationale, preclinical studies and ongoing clinical trials. Leukemia 22 (2008) 23-30
-
(2008)
Leukemia
, vol.22
, pp. 23-30
-
-
Pardanani, A.1
-
29
-
-
42249091014
-
Somatically acquired JAK1 mutations in adult acute lymphoblastic leukemia
-
Flex E., Petrangeli V., Stella L., et al. Somatically acquired JAK1 mutations in adult acute lymphoblastic leukemia. J Exp Med 205 (2008) 751-758
-
(2008)
J Exp Med
, vol.205
, pp. 751-758
-
-
Flex, E.1
Petrangeli, V.2
Stella, L.3
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