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Volumn 123, Issue 7, 2013, Pages 3099-3111

Integrated genetic and epigenetic analysis of childhood acute lymphoblastic leukemia

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CYTOSINE;

EID: 84879634027     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI66203     Document Type: Article
Times cited : (114)

References (75)
  • 1
    • 40749150603 scopus 로고    scopus 로고
    • Acute lymphoblastic leukaemia
    • DOI 10.1016/S0140-6736(08)60457-2, PII S0140673608604572
    • Pui CH, Robison LL, Look AT. Acute lymphoblastic leukaemia. Lancet. 2008;371(9617):1030-1043. (Pubitemid 351389536)
    • (2008) The Lancet , vol.371 , Issue.9617 , pp. 1030-1043
    • Pui, C.-H.1    Robison, L.L.2    Look, A.T.3
  • 2
    • 79952078495 scopus 로고    scopus 로고
    • Biology, risk stratification, and therapy of pediatric acute leukemias: An update
    • Pui CH, Carroll WL, Meshinchi S, Arceci RJ. Biology, risk stratification, and therapy of pediatric acute leukemias: an update. J Clin Oncol . 2011; 29(5):551-565.
    • (2011) J Clin Oncol , vol.29 , Issue.5 , pp. 551-565
    • Pui, C.H.1    Carroll, W.L.2    Meshinchi, S.3    Arceci, R.J.4
  • 3
    • 19044399684 scopus 로고    scopus 로고
    • Classification, subtype discovery, and prediction of outcome in pediatric acute lymphoblastic leukemia by gene expression profiling
    • Yeoh EJ, et al. Classification, subtype discovery, and prediction of outcome in pediatric acute lymphoblastic leukemia by gene expression profiling. Cancer Cell. 2002;1(2):133-143.
    • (2002) Cancer Cell , vol.1 , Issue.2 , pp. 133-143
    • Yeoh, E.J.1
  • 4
    • 0033178875 scopus 로고    scopus 로고
    • Protracted and variable latency of acute lymphoblastic leukemia after TEL-AML1 gene fusion in utero
    • Wiemels JL, Ford AM, Van Wering ER, Postma A, Greaves M. Protracted and variable latency of acute lymphoblastic leukemia after TEL-AML1 gene fusion in utero. Blood. 1999;94(3):1057-1062. (Pubitemid 29361838)
    • (1999) Blood , vol.94 , Issue.3 , pp. 1057-1062
    • Wiemels, J.L.1    Ford, A.M.2    Van Wering, E.R.3    Postma, A.4    Greaves, M.5
  • 5
    • 58149095544 scopus 로고    scopus 로고
    • Cytogenetics of paediatric and adolescent acute lymphoblastic leukaemia
    • Harrison CJ. Cytogenetics of paediatric and adolescent acute lymphoblastic leukaemia. Br J Haematol. 2009;144(2):147-156.
    • (2009) Br J Haematol , vol.144 , Issue.2 , pp. 147-156
    • Harrison, C.J.1
  • 6
    • 57549097632 scopus 로고    scopus 로고
    • Global genomic characterization of acute lymphoblastic leukemia
    • Mullighan CG, Downing JR. Global genomic characterization of acute lymphoblastic leukemia. Semin Hematol. 2009;46(1):3-15.
    • (2009) Semin Hematol. , vol.46 , Issue.1 , pp. 3-15
    • Mullighan, C.G.1    Downing, J.R.2
  • 8
    • 58749109707 scopus 로고    scopus 로고
    • Deletion of IKZF1 and prognosis in acute lymphoblastic leukemia
    • Mullighan CG, et al. Deletion of IKZF1 and prognosis in acute lymphoblastic leukemia. N Engl J Med. 2009;360(5):470-480.
    • (2009) N Engl J Med. , vol.360 , Issue.5 , pp. 470-480
    • Mullighan, C.G.1
  • 9
    • 70449719091 scopus 로고    scopus 로고
    • IKZF1 (Ikaros) deletions in BCR-ABL1- positive acute lymphoblastic leukemia are associated with short disease-free survival and high rate of cumulative incidence of relapse: A GIMEMA AL WP report
    • Martinelli G, et al. IKZF1 (Ikaros) deletions in BCR-ABL1- positive acute lymphoblastic leukemia are associated with short disease-free survival and high rate of cumulative incidence of relapse: a GIMEMA AL WP report. J Clin Oncol. 2009;27(31):5202-5207.
    • (2009) J Clin Oncol. , vol.27 , Issue.31 , pp. 5202-5207
    • Martinelli, G.1
  • 10
    • 73649110641 scopus 로고    scopus 로고
    • DNA methylation signatures identify biologically distinct subtypes in acute myeloid leukemia
    • Figueroa ME, et al. DNA methylation signatures identify biologically distinct subtypes in acute myeloid leukemia. Cancer Cell. 2010;17(1):27.
    • (2010) Cancer Cell. , vol.17 , Issue.1 , pp. 27
    • Figueroa, M.E.1
  • 11
    • 78650019179 scopus 로고    scopus 로고
    • Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation
    • Figueroa ME, et al. Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation. Cancer Cell. 2010;18(6):553-567.
    • (2010) Cancer Cell. , vol.18 , Issue.6 , pp. 553-567
    • Figueroa, M.E.1
  • 12
    • 0031035406 scopus 로고    scopus 로고
    • Frequent and selective methylation of p15 and deletion of both p15 and p16 in T-cell acute lymphoblastic leukemia
    • Batova A, et al. Frequent and selective methylation of p15 and deletion of both p15 and p16 in T-cell acute lymphoblastic leukemia. Cancer Res. 1997; 57(5):832-836. (Pubitemid 27098004)
    • (1997) Cancer Research , vol.57 , Issue.5 , pp. 832-836
    • Batova, A.1    Diccianni, M.B.2    Yu, J.C.3    Nobori, T.4    Link, M.P.5    Pullen, J.6    Yu, A.L.7
  • 13
    • 0037455720 scopus 로고    scopus 로고
    • Methylation of CpG dinucleotides and/or CCWGG motifs at the promoter of TP53 correlates with decreased gene expression in a subset of acute lymphoblastic leukemia patients
    • DOI 10.1038/sj.onc.1206236
    • Agirre X, Vizmanos JL, Calasanz MJ, Garcia-Delgado M, Larrayoz MJ, Novo FJ. Methylation of CpG dinucleotides and/or CCWGG motifs at the promoter of TP53 correlates with decreased gene expression in a subset of acute lymphoblastic leukemia patients. Oncogene. 2003;22(7):1070-1072. (Pubitemid 36313150)
    • (2003) Oncogene , vol.22 , Issue.7 , pp. 1070-1072
    • Agirre, X.1    Vizmanos, J.L.2    Calasanz, M.J.3    Garcia-Delgado, M.4    Larrayoz, M.J.5    Novo, F.J.6
  • 15
    • 1542615070 scopus 로고    scopus 로고
    • Hypermethylation of the 5 2 CpG Island of the FHIT Gene Is Associated with Hyperdiploid and Translocation-Negative Subtypes of Pediatric Leukemia
    • DOI 10.1158/0008-5472.CAN-03-2387
    • Zheng S, et al. Hypermethylation of the 5 2 CpG island of the FHIT gene is associated with hyperdiploid and translocation-negative subtypes of pediatric leukemia. Cancer Res. 2004;64(6):2000-2006. (Pubitemid 38339446)
    • (2004) Cancer Research , vol.64 , Issue.6 , pp. 2000-2006
    • Zheng, S.1    Ma, X.2    Zhang, L.3    Gunn, L.4    Smith, M.T.5    Wiemels, J.L.6    Leung, K.7    Buffler, P.A.8    Wiencke, J.K.9
  • 18
    • 27244438584 scopus 로고    scopus 로고
    • Lack of CpG island methylator phenotype defines a clinical subtype of T-cell acute lymphoblastic leukemia associated with good prognosis
    • Roman-Gomez J, Jimenez-Velasco A, Agirre X, Prosper F, Heiniger A, Torres A. Lack of CpG island methylator phenotype defines a clinical subtype of T-cell acute lymphoblastic leukemia associated with good prognosis. J Clin Oncol. 2005;23(28):7043-7049.
    • (2005) J Clin Oncol , vol.23 , Issue.28 , pp. 7043-7049
    • Roman-Gomez, J.1    Jimenez-Velasco, A.2    Agirre, X.3    Prosper, F.4    Heiniger, A.5    Torres, A.6
  • 19
    • 34548734299 scopus 로고    scopus 로고
    • Ultradeep bisulfite sequencing analysis of DNA methylation patterns in multiple gene promoters by 454 sequencing
    • DOI 10.1158/0008-5472.CAN-07-1016
    • Taylor KH, et al. Ultradeep bisulfite sequencing analysis of DNA methylation patterns in multiple gene promoters by 454 sequencing. Cancer Res. 2007; 67(18):8511-8518. (Pubitemid 47437425)
    • (2007) Cancer Research , vol.67 , Issue.18 , pp. 8511-8518
    • Taylor, K.H.1    Kramer, R.S.2    Davis, J.W.3    Guo, J.4    Duff, D.J.5    Xu, D.6    Caldwell, C.W.7    Shi, H.8
  • 20
    • 76249112147 scopus 로고    scopus 로고
    • Specific promoter methylation identifies different subgroups of MLL-rearranged infant acute lymphoblastic leukemia, influences clinical outcome, and provides therapeutic options
    • Stumpel DJ, et al. Specific promoter methylation identifies different subgroups of MLL-rearranged infant acute lymphoblastic leukemia, influences clinical outcome, and provides therapeutic options. Blood. 2009;114(27):5490- 5498.
    • (2009) Blood , vol.114 , Issue.27 , pp. 5490-5498
    • Stumpel, D.J.1
  • 21
    • 77954721993 scopus 로고    scopus 로고
    • Promoter hypermethylation in MLL-r infant acute lymphoblastic leukemia: Biology and therapeutic targeting
    • Schafer E, et al. Promoter hypermethylation in MLL-r infant acute lymphoblastic leukemia: biology and therapeutic targeting. Blood . 2010; 115(23):4798-4809.
    • (2010) Blood , vol.115 , Issue.23 , pp. 4798-4809
    • Schafer, E.1
  • 22
    • 70349988272 scopus 로고    scopus 로고
    • The DNA methylome of pediatric acute lymphoblastic leukemia
    • Davidsson J, et al. The DNA methylome of pediatric acute lymphoblastic leukemia. Hum Mol Genet. 2009;18(21):4054-4065.
    • (2009) Hum Mol Genet , vol.18 , Issue.21 , pp. 4054-4065
    • Davidsson, J.1
  • 23
    • 77949536178 scopus 로고    scopus 로고
    • DNA methylation for subtype classification and prediction of treatment outcome in patients with childhood acute lymphoblastic leukemia
    • Milani L, et al. DNA methylation for subtype classification and prediction of treatment outcome in patients with childhood acute lymphoblastic leukemia. Blood. 2010;115(6):1214-1225.\
    • (2010) Blood , vol.115 , Issue.6 , pp. 1214-1225
    • Milani, L.1
  • 24
    • 0035532141 scopus 로고    scopus 로고
    • Estimating the number of data clusters via the gap statistic
    • Tibshirani R, Walther G, Hastie T. Estimating the number of data clusters via the gap statistic. J R Statist Soc. B. 2001;63(2):411-423.
    • (2001) J R Statist Soc. B. , vol.63 , Issue.2 , pp. 411-423
    • Tibshirani, R.1    Walther, G.2    Hastie, T.3
  • 25
    • 36749055295 scopus 로고    scopus 로고
    • Determining the number of clusters using the weighted gap statistic
    • DOI 10.1111/j.1541-0420.2007.00784.x
    • Yan M, Ye K. Determining the number of clusters using the weighted gap statistic. Biometrics . 2007; 63(4):1031-1037. (Pubitemid 350212562)
    • (2007) Biometrics , vol.63 , Issue.4 , pp. 1031-1037
    • Yan, M.1    Ye, K.2
  • 26
    • 0000008146 scopus 로고
    • Comparing partitions
    • Hubert L, Arabie P. Comparing partitions. J Classif. 1985;2(1):193-218.
    • (1985) J Classif , vol.2 , Issue.1 , pp. 193-218
    • Hubert, L.1    Arabie, P.2
  • 27
    • 4544341015 scopus 로고    scopus 로고
    • Linear models and empirical Bayes methods for assessing differential expression in microarray experiments
    • Smyth G. Linear models and empirical Bayes methods for assessing differential expression in microarray experiments. Stat Appl Genet Mol Biol. 2004;3:Article 3.
    • (2004) Stat Appl Genet Mol Biol , vol.3 , pp. 3
    • Smyth, G.1
  • 28
    • 67249146555 scopus 로고    scopus 로고
    • JAK mutations in high-risk childhood acute lymphoblastic leukemia
    • Mullighan CG, et al. JAK mutations in high-risk childhood acute lymphoblastic leukemia. Proc Natl Acad Sci U S A. 2009;106(23):9414-9418.
    • (2009) Proc Natl Acad Sci U S a , vol.106 , Issue.23 , pp. 9414-9418
    • Mullighan, C.G.1
  • 29
    • 70350519430 scopus 로고    scopus 로고
    • Deregulated expression of cytokine receptor gene, CRLF2, is involved in lymphoid transformation in B-cell precursor acute lymphoblastic leukemia
    • Russell LJ, et al. Deregulated expression of cytokine receptor gene, CRLF2, is involved in lymphoid transformation in B-cell precursor acute lymphoblastic leukemia. Blood. 2009;114(13):2688-2698.
    • (2009) Blood , vol.114 , Issue.13 , pp. 2688-2698
    • Russell, L.J.1
  • 32
    • 49449117541 scopus 로고    scopus 로고
    • Genome-wide identification of aberrantly methylated promoter associated CpG islands in acute lymphocytic leukemia
    • Kuang SQ, et al. Genome-wide identification of aberrantly methylated promoter associated CpG islands in acute lymphocytic leukemia. Leukemia . 2008;22(8):1529-1538.
    • (2008) Leukemia , vol.22 , Issue.8 , pp. 1529-1538
    • Kuang, S.Q.1
  • 33
    • 77954126563 scopus 로고    scopus 로고
    • Large-scale analysis of DNA methylation in chronic lymphocytic leukemia
    • Arthur GL, et al. Large-scale analysis of DNA methylation in chronic lymphocytic leukemia. Epigenomics. 2009;1(1):39-61.
    • (2009) Epigenomics , vol.1 , Issue.1 , pp. 39-61
    • Arthur, G.L.1
  • 34
    • 77957370748 scopus 로고    scopus 로고
    • Genome-wide DNA methylation profiling of chronic lymphocytic leukemia allows identification of epigenetically repressed molecular pathways with clinical impact
    • Tong W-G, et al. Genome-wide DNA methylation profiling of chronic lymphocytic leukemia allows identification of epigenetically repressed molecular pathways with clinical impact. Epigenetics. 2010; 5(6):499-508.
    • (2010) Epigenetics , vol.5 , Issue.6 , pp. 499-508
    • Tong, W.-G.1
  • 35
    • 77957928566 scopus 로고    scopus 로고
    • DNA methylation profiles and their relationship with cytogenetic status in adult acute myeloid leukemia
    • Alvarez S, et al. DNA methylation profiles and their relationship with cytogenetic status in adult acute myeloid leukemia. PLoS One. 2010;5(8):e12197.
    • (2010) PLoS One , vol.5 , Issue.8
    • Alvarez, S.1
  • 36
    • 77449157068 scopus 로고    scopus 로고
    • Quantitative DNA-methylation predicts survival in adult acute myeloid leukemia
    • Bullinger L, et al. Quantitative DNA-methylation predicts survival in adult acute myeloid leukemia. Blood. 2010;115(3):636-642.
    • (2010) Blood , vol.115 , Issue.3 , pp. 636-642
    • Bullinger, L.1
  • 37
    • 70350720044 scopus 로고    scopus 로고
    • MDS and secondary AML display unique patterns and abundance of aberrant DNA methylation
    • Figueroa ME, et al. MDS and secondary AML display unique patterns and abundance of aberrant DNA methylation. Blood. 2009;114(16):3448-3458.
    • (2009) Blood , vol.114 , Issue.16 , pp. 3448-3458
    • Figueroa, M.E.1
  • 38
    • 60849089645 scopus 로고    scopus 로고
    • Aberrant DNA methylation is a dominant mechanism in MDS progression to AML
    • Jiang Y, et al. Aberrant DNA methylation is a dominant mechanism in MDS progression to AML. Blood. 2008;113(6):1315-1325.
    • (2008) Blood , vol.113 , Issue.6 , pp. 1315-1325
    • Jiang, Y.1
  • 39
    • 61849117834 scopus 로고    scopus 로고
    • Residual DNA methylation at remission is prognostic in adult Philadelphia chromo-some-negative acute lymphocytic leukemia
    • Yang H, et al. Residual DNA methylation at remission is prognostic in adult Philadelphia chromo-some-negative acute lymphocytic leukemia. Blood. 2009;113(9):1892-1898.
    • (2009) Blood , vol.113 , Issue.9 , pp. 1892-1898
    • Yang, H.1
  • 40
    • 70350654370 scopus 로고    scopus 로고
    • DNA methylation protects hematopoietic stem cell multipotency from myeloerythroid restriction
    • Broske A-M, et al. DNA methylation protects hematopoietic stem cell multipotency from myeloerythroid restriction. Nat Genet. 2009;41(11):1207-1215.
    • (2009) Nat Genet. , vol.41 , Issue.11 , pp. 1207-1215
    • Broske, A.-M.1
  • 41
    • 0036494563 scopus 로고    scopus 로고
    • Min/+ Dnmt1-hypomorphic mice
    • Eads CA, Nickel AE, Laird PW. Complete genetic suppression of polyp formation and reduction of CpG-island hypermethylation in Apc(Min/+) Dnmt1-hypomorphic mice. Cancer Res . 2002; 62(5):1296-1299. (Pubitemid 34407781)
    • (2002) Cancer Research , vol.62 , Issue.5 , pp. 1296-1299
    • Eads, C.A.1    Nickel, A.E.2    Laird, P.W.3
  • 42
    • 0036232616 scopus 로고    scopus 로고
    • DNA methyltransferase deficiency modifies cancer susceptibility in mice lacking DNA mismatch repair
    • DOI 10.1128/MCB.22.9.2906-2917.2002
    • Trinh BN, Long TI, Nickel AE, Shibata D, Laird PW. DNA Methyltransferase deficiency modifies cancer susceptibility in mice lacking DNA mismatch repair. Mol Cell Biol. 2002;22(9):2906-2917. (Pubitemid 34437450)
    • (2002) Molecular and Cellular Biology , vol.22 , Issue.9 , pp. 2906-2917
    • Trinh, B.N.1    Long, T.I.2    Nickel, A.E.3    Shibata, D.4    Laird, P.W.5
  • 43
    • 77956902023 scopus 로고    scopus 로고
    • Comprehensive methylome map of lineage commitment from haematopoietic progenitors
    • Ji H, et al. Comprehensive methylome map of lineage commitment from haematopoietic progenitors. Nature. 2010;467(7313):338-342.
    • (2010) Nature , vol.467 , Issue.7313 , pp. 338-342
    • Ji, H.1
  • 45
    • 0036463950 scopus 로고    scopus 로고
    • Expression of a conditional AML1-ETO oncogene bypasses embryonic lethality and establishes a murine model of human t(8;21) acute myeloid leukemia
    • DOI 10.1016/S1535-6108(02)00016-8
    • Higuchi M, O'Brien D, Kumaravelu P, Lenny N, Yeoh EJ, Downing JR. Expression of a conditional AML1-ETO oncogene bypasses embryonic lethality and establishes a murine model of human t(8;21) acute myeloid leukemia. Cancer Cell. 2002;1(1):63-74. (Pubitemid 41039177)
    • (2002) Cancer Cell , vol.1 , Issue.1 , pp. 63-74
    • Higuchi, M.1    O'Brien, D.2    Kumaravelu, P.3    Lenny, N.4    Yeoh, E.-J.5    Downing, J.R.6
  • 46
    • 77951443641 scopus 로고    scopus 로고
    • The cytoplasmic NPM mutant induces myeloproliferation in a transgenic mouse model
    • Cheng K, et al. The cytoplasmic NPM mutant induces myeloproliferation in a transgenic mouse model. Blood. 2010;115(16):3341-3345.
    • (2010) Blood , vol.115 , Issue.16 , pp. 3341-3345
    • Cheng, K.1
  • 47
    • 2342512105 scopus 로고    scopus 로고
    • TEL-AML1 promotes development of specific hematopoietic lineages consistent with preleukemic activity
    • DOI 10.1182/blood-2003-10-3695
    • Morrow M, Horton S, Kioussis D, Brady HJ, Williams O. TEL-AML1 promotes development of specific hematopoietic lineages consistent with preleukemic activity. Blood. 2004;103(10):3890-3896. (Pubitemid 38596310)
    • (2004) Blood , vol.103 , Issue.10 , pp. 3890-3896
    • Morrow, M.1    Horton, S.2    Kioussis, D.3    Brady, H.J.M.4    Williams, O.5
  • 49
    • 0027184079 scopus 로고
    • Chimeric homeobox gene E2A-PBX1 induces proliferation, apoptosis, and malignant lymphomas in transgenic mice
    • DOI 10.1016/0092-8674(93)90463-Z
    • Dedera DA, et al. Chimeric homeobox gene E2APBX1 induces proliferation, apoptosis, and malignant lymphomas in transgenic mice. Cell . 1993; 74(5):833-843. (Pubitemid 23270603)
    • (1993) Cell , vol.74 , Issue.5 , pp. 833-843
    • Dedera, D.A.1    Waller, E.K.2    LeBrun, D.P.3    Sen-Majumdar, A.4    Stevens, M.E.5    Barsh, G.S.6    Cleary, M.L.7
  • 50
    • 0027434620 scopus 로고
    • E2A-Pbx1, the t(1;19) translocation protein of human pre-B-cell acute lymphocytic leukemia, causes acute myeloid leukemia in mice
    • Kamps MP, Baltimore D. E2A-Pbx1, the t(1;19) translocation protein of human pre-B-cell acute lymphocytic leukemia, causes acute myeloid leukemia in mice. Mol Cell Biol. 1993;13(1):351-357. (Pubitemid 23006912)
    • (1993) Molecular and Cellular Biology , vol.13 , Issue.1 , pp. 351-357
    • Kamps, M.P.1    Baltimore, D.2
  • 51
    • 79958046078 scopus 로고    scopus 로고
    • Gene expression and single nucleotide polymorphism array analyses of spindle cell lipomas and conventional lipomas with 13q14 deletion
    • Bartuma H, et al. Gene expression and single nucleotide polymorphism array analyses of spindle cell lipomas and conventional lipomas with 13q14 deletion. Genes Chromosomes Cancer . 2011; 50(8):619-632.
    • (2011) Genes Chromosomes Cancer , vol.50 , Issue.8 , pp. 619-632
    • Bartuma, H.1
  • 52
    • 0037818296 scopus 로고    scopus 로고
    • L, induces a caspase-independent autophagic cell death
    • DOI 10.1038/sj.cdd.4401246
    • Yanagisawa H, Miyashita T, Nakano Y, Yamamoto D. HSpin1, a transmembrane protein interacting with Bcl-2/Bcl-xL, induces a caspase-independent autophagic cell death. Cell Death Differ . 2003; 10(7):798-807. (Pubitemid 36850241)
    • (2003) Cell Death and Differentiation , vol.10 , Issue.7 , pp. 798-807
    • Yanagisawa, H.1    Miyashita, T.2    Nakano, Y.3    Yamamoto, D.4
  • 53
    • 34548131144 scopus 로고    scopus 로고
    • CDKN2B methylation status and isolated chromosome 7 abnormalities predict responses to treatment with 5-azacytidine
    • DOI 10.1038/sj.leu.2404796, PII 2404796
    • Raj K, et al. CDKN2B methylation status and isolated chromosome 7 abnormalities predict responses to treatment with 5-azacytidine. Leukemia . 2007;21(9):1937-1944. (Pubitemid 47299967)
    • (2007) Leukemia , vol.21 , Issue.9 , pp. 1937-1944
    • Raj, K.1    John, A.2    Ho, A.3    Chronis, C.4    Khan, S.5    Samuel, J.6    Pomplun, S.7    Thomas, N.S.B.8    Mufti, G.J.9
  • 55
    • 76749138468 scopus 로고    scopus 로고
    • Long-term results of St Jude Total Therapy Studies 11, 12, 13A, 13B, and 14 for childhood acute lymphoblastic leukemia
    • Pui CH, et al. Long-term results of St Jude Total Therapy Studies 11, 12, 13A, 13B, and 14 for childhood acute lymphoblastic leukemia. Leukemia. 2010; 24(2):371-382.
    • (2010) Leukemia , vol.24 , Issue.2 , pp. 371-382
    • Pui, C.H.1
  • 56
    • 67649410242 scopus 로고    scopus 로고
    • Treating childhood acute lymphoblastic leukemia without cranial irradiation
    • Pui CH, et al. Treating childhood acute lymphoblastic leukemia without cranial irradiation. N Engl J Med. 2009;360(26):2730-2741.
    • (2009) N Engl J Med , vol.360 , Issue.26 , pp. 2730-2741
    • Pui, C.H.1
  • 58
    • 70350680415 scopus 로고    scopus 로고
    • Rearrangement of CRLF2 in B-progenitor- and Down syndrome-associated acute lymphoblastic leukemia
    • Mullighan CG, et al. Rearrangement of CRLF2 in B-progenitor- and Down syndrome-associated acute lymphoblastic leukemia. Nature Genetics. 2009; 41(11):1243-1246.
    • (2009) Nature Genetics , vol.41 , Issue.11 , pp. 1243-1246
    • Mullighan, C.G.1
  • 59
    • 57549119069 scopus 로고    scopus 로고
    • ERG deletions define a novel subtype of B-progenitor acute lymphoblastic leukemia
    • Mullighan CG, et al. ERG deletions define a novel subtype of B-progenitor acute lymphoblastic leukemia. Blood. 2007;110:691.
    • (2007) Blood , vol.110 , pp. 691
    • Mullighan, C.G.1
  • 60
    • 58749095816 scopus 로고    scopus 로고
    • Early T-cell precursor leukaemia: A subtype of very high-risk acute lymphoblastic leukaemia
    • Coustan-Smith E, et al. Early T-cell precursor leukaemia: a subtype of very high-risk acute lymphoblastic leukaemia. Lancet Oncol. 2009;10(2):147-156.
    • (2009) Lancet Oncol , vol.10 , Issue.2 , pp. 147-156
    • Coustan-Smith, E.1
  • 61
    • 84862907593 scopus 로고    scopus 로고
    • The genetic basis of early T-cell precursor acute lymphoblastic leukaemia
    • Zhang J, et al. The genetic basis of early T-cell precursor acute lymphoblastic leukaemia. Nature. 2012; 481(7380):157-163.
    • (2012) Nature , vol.481 , Issue.7380 , pp. 157-163
    • Zhang, J.1
  • 64
    • 65649104706 scopus 로고    scopus 로고
    • Genome-wide determination of DNA methylation by Hpa II tiny fragment enrichment by ligation-mediated PCR (HELP) for the study of acute leukemias
    • Figueroa ME, Melnick A, Greally JM. Genome-wide determination of DNA methylation by Hpa II tiny fragment enrichment by ligation-mediated PCR (HELP) for the study of acute leukemias. Methods Mol Biol. 2009;538:395-407.
    • (2009) Methods Mol Biol , vol.538 , pp. 395-407
    • Figueroa, M.E.1    Melnick, A.2    Greally, J.M.3
  • 66
    • 46749153406 scopus 로고    scopus 로고
    • An integrative genomic and epigenomic approach for the study of transcriptional regulation
    • Figueroa ME, et al. An integrative genomic and epigenomic approach for the study of transcriptional regulation. PLoS One. 2008;3(3):e1882.
    • (2008) PLoS One , vol.3 , Issue.3
    • Figueroa, M.E.1
  • 67
    • 42649129709 scopus 로고    scopus 로고
    • An analytical pipeline for genomic representations used for cytosine methylation studies
    • Thompson RF RM. An analytical pipeline for genomic representations used for cytosine methylation studies. Bioinformatics. 2008;24(9):1161-1167.
    • (2008) Bioinformatics , vol.24 , Issue.9 , pp. 1161-1167
    • Thompson, R.F.R.M.1
  • 69
    • 28744458859 scopus 로고    scopus 로고
    • Bioconductor: Open software development for computational biology and bioinformatics
    • Gentleman R, et al. Bioconductor: open software development for computational biology and bioinformatics. Genome Biol. 2004;5(10):R80.
    • (2004) Genome Biol , vol.5 , Issue.10
    • Gentleman, R.1
  • 70
    • 20444406724 scopus 로고    scopus 로고
    • The ade4 package - I: One-table methods
    • Chessel D, Dufour AB, Thioulouse J. The ade4 package - I: One-table methods. R News. 2004;4:5-10.
    • (2004) R News , vol.4 , pp. 5-10
    • Chessel, D.1    Dufour, A.B.2    Thioulouse, J.3
  • 71
    • 0001677717 scopus 로고
    • Controlling the False Discovery Rate: A practical and powerful approach to multiple testing
    • Benjamini Y HY. Controlling the False Discovery Rate: A practical and powerful approach to multiple testing. J R Stat Soc Ser B. 1995;57(1):289-300.
    • (1995) J R Stat Soc Ser B , vol.57 , Issue.1 , pp. 289-300
    • Benjamini, Y.H.Y.1
  • 72
    • 61449172037 scopus 로고    scopus 로고
    • Systemic and integrative analysis of large gene lists using DAVID Bioinformatics Resources
    • Huang DW, Sherman BT, Lempicki RA. Systemic and integrative analysis of large gene lists using DAVID Bioinformatics Resources. Nat Protoc. 2009; 4(1):44-57.
    • (2009) Nat Protoc , vol.4 , Issue.1 , pp. 44-57
    • Huang, D.W.1    Sherman, B.T.2    Lempicki, R.A.3
  • 73
    • 58549112996 scopus 로고    scopus 로고
    • Bioinformatics enrichment tools: Paths toward the comprehensive functional analysis of large gene lists
    • Huang DW, Sherman BT, Lempicki RA. Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists. Nucleic Acids Res. 2009;37(1):1-13.
    • (2009) Nucleic Acids Res , vol.37 , Issue.1 , pp. 1-13
    • Huang, D.W.1    Sherman, B.T.2    Lempicki, R.A.3
  • 74
    • 58149178579 scopus 로고    scopus 로고
    • NCBI Reference Sequences: Current status, policy and new initiatives
    • Pruitt KD, Tatusova T, Klimke W, Maglott DR. NCBI Reference Sequences: current status, policy and new initiatives. Nucleic Acids Res. 2009; 37(Database issue):D32-D36.
    • (2009) Nucleic Acids Res , vol.37 , Issue.DATABASE ISSUE
    • Pruitt, K.D.1    Tatusova, T.2    Klimke, W.3    Maglott, D.R.4
  • 75
    • 0036081355 scopus 로고    scopus 로고
    • Gene Expression Omnibus: NCBI gene expression and hybridization array data repository
    • Edgar R, Domrachev M, Lash AE. Gene Expression Omnibus: NCBI gene expression and hybridization array data repository. Nucl Acids Res . 2002; 30(1):207-210. (Pubitemid 34679544)
    • (2002) Nucleic Acids Research , vol.30 , Issue.1 , pp. 207-210
    • Edgar, R.1    Domrachev, M.2    Lash, A.E.3


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