Oncogenic IL7R gain-of-function mutations in childhood T-cell acute lymphoblastic leukemia

Nature Genetics

Volumn 43, Issue 10, 2011, Pages 932-941

  Zenatti, Priscila P ^a   Ribeiro, Daniel ^b   Li, Wenqing ^c   Zuurbier, Linda ^d   Silva, Milene C ^b   Paganin, Maddalena ^e   Tritapoe, Julia ^c   Hixon, Julie A ^c   Silveira, André B ^a   Cardoso, Bruno A ^b   Sarmento, Leonor M ^b   Correia, Nádia ^b   Toribio, Maria L ^f   Kobarg, Jörg ^g   Horstmann, Martin ^h,i   Pieters, Rob ^d   Brandalise, Silvia R ^a,j   Ferrando, Adolfo A ^e   Meijerink, Jules P ^d   Durum, Scott K ^c   Yunes, J Andrés ^a,j   Barata, João T ^b   more..

^a CENTRO INFANTIL BOLDRINI   (Brazil)

^b INSTITUTO DE MEDICINA MOLECULAR   (Portugal)

^c NATIONAL CANCER INSTITUTE   (United States)

^d SOPHIA CHILDREN S HOSPITAL   (Netherlands)

^e NewYork Presbyterian Hospital   (United States)

^f UNIVERSIDAD AUTÓNOMA DE MADRID   (Spain)

^g BRAZILIAN CENTER FOR RESEARCH IN ENERGY AND MATERIALS CNPEM   (Brazil)

^h German Cooperative Study Group for Childhood Acute Lymphoblastic Leukemia (COALL)   (Germany)

ⁱ UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

^j UNIVERSITY OF CAMPINAS   (Brazil)

more..

Author keywords

[No Author keywords available]

Indexed keywords

CYSTEINE; INTERKEUKIN 17 GAMMA C; INTERLEUKIN 17; INTERLEUKIN 17 RECEPTOR; INTERLEUKIN 17 RECEPTOR ALPHA; INTERLEUKIN RECEPTOR; JANUS KINASE 1; JANUS KINASE 3; UNCLASSIFIED DRUG;

ARTICLE; CELL TRANSFORMATION; CHILDHOOD LEUKEMIA; DISULFIDE BOND; EXON; EXTRACELLULAR SPACE; GAIN OF FUNCTION MUTATION; GENE ACTIVATION; GENE EXPRESSION; GENE MUTATION; LEUKEMOGENESIS; NUCLEOTIDE SEQUENCE; ONCOGENE; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; T CELL ACUTE LYMPHOBLASTIC LEUKEMIA;

ANIMALS; CELL CYCLE; CELL LINE; CELL SURVIVAL; CHILD; CYSTEINE; DNA MUTATIONAL ANALYSIS; EXONS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, LEUKEMIC; HOMEODOMAIN PROTEINS; HUMANS; INTERLEUKIN-7; JANUS KINASE 1; JANUS KINASE 3; MICE; MICE, KNOCKOUT; MUTATION; ONCOGENES; PRECURSOR T-CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA; RECEPTORS, INTERLEUKIN-7; RNA, SMALL INTERFERING; SEQUENCE ANALYSIS, DNA; SIGNAL TRANSDUCTION; T-LYMPHOCYTES; TRANSFECTION; TUMOR CELLS, CULTURED;

EID: 80053385665     PISSN: 10614036     EISSN: 15461718     Source Type: Journal    
DOI: 10.1038/ng.924     Document Type: Article

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