-
1
-
-
0141920503
-
Burden of major musculoskeletal conditions
-
Woolf AD, Pfleger B. Burden of major musculoskeletal conditions. Bull World Health Organ 2003; 81: 646-656.
-
(2003)
Bull World Health Organ
, vol.81
, pp. 646-656
-
-
Woolf, A.D.1
Pfleger, B.2
-
2
-
-
84883356204
-
The global economic cost of osteoarthritis: how the UK compares
-
Chen A, Gupte C, Akhtar K, et al. The global economic cost of osteoarthritis: how the UK compares. Arthritis 2012; 2012: 698709-698714.
-
(2012)
Arthritis
, vol.2012
, pp. 698709-698714
-
-
Chen, A.1
Gupte, C.2
Akhtar, K.3
-
3
-
-
29244433028
-
Financial cost of osteoarthritis in France. The 'COART' France study
-
Le Pen C, Reygrobellet C, Gerentes I. Financial cost of osteoarthritis in France. The 'COART' France study. Joint Bone Spine 2005; 72: 567-570.
-
(2005)
Joint Bone Spine
, vol.72
, pp. 567-570
-
-
Le Pen, C.1
Reygrobellet, C.2
Gerentes, I.3
-
5
-
-
77950021805
-
OARSI recommendations for the management of hip and knee osteoarthritis: part III: changes in evidence following systematic cumulative update of research published through January 2009
-
Zhang W, Nuki G, Moskowitz RW, et al. OARSI recommendations for the management of hip and knee osteoarthritis: part III: changes in evidence following systematic cumulative update of research published through January 2009. Osteoarthritis Cartilage 2010; 18: 476-499.
-
(2010)
Osteoarthritis Cartilage
, vol.18
, pp. 476-499
-
-
Zhang, W.1
Nuki, G.2
Moskowitz, R.W.3
-
6
-
-
58849159153
-
Clinical responses to gene therapy in joints of two subjects with rheumatoid arthritis
-
Wehling P, Reinecke J, Baltzer AW, et al. Clinical responses to gene therapy in joints of two subjects with rheumatoid arthritis. Hum Gene Ther 2009; 20: 97-101.
-
(2009)
Hum Gene Ther
, vol.20
, pp. 97-101
-
-
Wehling, P.1
Reinecke, J.2
Baltzer, A.W.3
-
7
-
-
84862934902
-
Initial phase I safety of retrovirally transduced human chondrocytes expressing transforming growth factor-beta-1 in degenerative arthritis patients
-
Ha CW, Noh MJ, Choi KB, et al. Initial phase I safety of retrovirally transduced human chondrocytes expressing transforming growth factor-beta-1 in degenerative arthritis patients. Cytotherapy 2012; 14: 247-256.
-
(2012)
Cytotherapy
, vol.14
, pp. 247-256
-
-
Ha, C.W.1
Noh, M.J.2
Choi, K.B.3
-
8
-
-
0034041974
-
Gene delivery to human chondrocytes by an adeno-associated virus vector
-
Arai Y, Kubo T, Fushiki S, et al. Gene delivery to human chondrocytes by an adeno-associated virus vector. J Rheumatol 2000; 27: 979-982.
-
(2000)
J Rheumatol
, vol.27
, pp. 979-982
-
-
Arai, Y.1
Kubo, T.2
Fushiki, S.3
-
9
-
-
0037338160
-
Efficient and persistent gene transfer into articular cartilage using recombinant adeno-associated virus vectors in vitro and in vivo
-
Madry H, Cucchiarini M, Terwilliger EF, et al. Efficient and persistent gene transfer into articular cartilage using recombinant adeno-associated virus vectors in vitro and in vivo. Human Gene Ther 2003; 14: 393-402.
-
(2003)
Human Gene Ther
, vol.14
, pp. 393-402
-
-
Madry, H.1
Cucchiarini, M.2
Terwilliger, E.F.3
-
10
-
-
84868657138
-
Chondrogenesis, chondrocyte differentiation, and articular cartilage metabolism in health and osteoarthritis
-
Goldring MB. Chondrogenesis, chondrocyte differentiation, and articular cartilage metabolism in health and osteoarthritis. Ther Adv Musculoskelet Dis 2012; 4: 269-285.
-
(2012)
Ther Adv Musculoskelet Dis
, vol.4
, pp. 269-285
-
-
Goldring, M.B.1
-
11
-
-
78650983649
-
Role of proinflammatory cytokines in the pathophysiology of osteoarthritis
-
Kapoor M, Martel-Pelletier J, Lajeunesse D, et al. Role of proinflammatory cytokines in the pathophysiology of osteoarthritis. Nat Rev Rheumatol 2010; 7: 33-42.
-
(2010)
Nat Rev Rheumatol
, vol.7
, pp. 33-42
-
-
Kapoor, M.1
Martel-Pelletier, J.2
Lajeunesse, D.3
-
13
-
-
84856620553
-
Aetiology of osteoarthritis: genetics and synovial joint development
-
Sandell LJ. Aetiology of osteoarthritis: genetics and synovial joint development. Nat Rev Rheumatol 2012; 8: 77-89.
-
(2012)
Nat Rev Rheumatol
, vol.8
, pp. 77-89
-
-
Sandell, L.J.1
-
14
-
-
78650977864
-
Genetic epidemiology of hip and knee osteoarthritis
-
Valdes AM, Spector TD. Genetic epidemiology of hip and knee osteoarthritis. Nat Rev Rheumatol 2011; 7: 23-32.
-
(2011)
Nat Rev Rheumatol
, vol.7
, pp. 23-32
-
-
Valdes, A.M.1
Spector, T.D.2
-
15
-
-
84855993582
-
Biomechanical factors in osteoarthritis
-
Guilak F. Biomechanical factors in osteoarthritis. Best Pract Res Clin Rheumatol 2012; 25: 815-823.
-
(2012)
Best Pract Res Clin Rheumatol
, vol.25
, pp. 815-823
-
-
Guilak, F.1
-
17
-
-
84861994775
-
Effects of ageing on articular cartilage homeostasis
-
Lotz M, Loeser RF. Effects of ageing on articular cartilage homeostasis. Bone 2012; 51: 241-248.
-
(2012)
Bone
, vol.51
, pp. 241-248
-
-
Lotz, M.1
Loeser, R.F.2
-
18
-
-
79952814836
-
Osteoarthritis year 2010 in review: pathomechanisms
-
van den Berg WB. Osteoarthritis year 2010 in review: pathomechanisms. Osteoarthritis Cartilage 2011; 19: 338-341.
-
(2011)
Osteoarthritis Cartilage
, vol.19
, pp. 338-341
-
-
van den Berg, W.B.1
-
19
-
-
84856667040
-
Epigenomic and microRNA-mediated regulation in cartilage development, homeostasis, and osteoarthritis
-
Goldring MB, Marcu KB. Epigenomic and microRNA-mediated regulation in cartilage development, homeostasis, and osteoarthritis. Trends Mol Med 2011; 18: 109-118.
-
(2011)
Trends Mol Med
, vol.18
, pp. 109-118
-
-
Goldring, M.B.1
Marcu, K.B.2
-
20
-
-
70249083400
-
The elusive path to cartilage regeneration
-
Hunziker EB. The elusive path to cartilage regeneration. Adv Mater 2009; 21: 3419-3424.
-
(2009)
Adv Mater
, vol.21
, pp. 3419-3424
-
-
Hunziker, E.B.1
-
21
-
-
72949105817
-
Remodelling of human osteoarthritic cartilage by FGF-2, alone or combined with Sox9 via rAAV gene transfer
-
Cucchiarini M, Terwilliger EF, Kohn D, et al. Remodelling of human osteoarthritic cartilage by FGF-2, alone or combined with Sox9 via rAAV gene transfer. J Cell Mol Med 2009; 13: 2476-2488.
-
(2009)
J Cell Mol Med
, vol.13
, pp. 2476-2488
-
-
Cucchiarini, M.1
Terwilliger, E.F.2
Kohn, D.3
-
22
-
-
33846208305
-
Restoration of the extracellular matrix in human osteoarthritic articular cartilage by overexpression of the transcription factor SOX9
-
Cucchiarini M, Thurn T, Weimer A, et al. Restoration of the extracellular matrix in human osteoarthritic articular cartilage by overexpression of the transcription factor SOX9. Arthritis Rheum 2007; 56: 158-167.
-
(2007)
Arthritis Rheum
, vol.56
, pp. 158-167
-
-
Cucchiarini, M.1
Thurn, T.2
Weimer, A.3
-
23
-
-
84860467045
-
Benefits of rAAV-mediated IGF-I overexpression for the long term reconstruction of human osteoarthritic cartilage by modulation of the IGF-I axis
-
Weimer A, Madry H, Venkatesan JK, et al. Benefits of rAAV-mediated IGF-I overexpression for the long term reconstruction of human osteoarthritic cartilage by modulation of the IGF-I axis. Mol Med 2012; 18: 346-358.
-
(2012)
Mol Med
, vol.18
, pp. 346-358
-
-
Weimer, A.1
Madry, H.2
Venkatesan, J.K.3
-
24
-
-
84875186059
-
Arthritis gene therapy and its tortuous path into the clinic
-
Evans CH, Ghivizzani SC, Robbins PD. Arthritis gene therapy and its tortuous path into the clinic. Transl Res 2013; 161: 205-216.
-
(2013)
Transl Res
, vol.161
, pp. 205-216
-
-
Evans, C.H.1
Ghivizzani, S.C.2
Robbins, P.D.3
-
25
-
-
0028031550
-
Treatment of deep cartilage defects in the knee with autologous chondrocyte transplantation
-
Brittberg M, Lindahl A, Nilsson A, et al. Treatment of deep cartilage defects in the knee with autologous chondrocyte transplantation. N Engl J Med 1994; 331: 889-895.
-
(1994)
N Engl J Med
, vol.331
, pp. 889-895
-
-
Brittberg, M.1
Lindahl, A.2
Nilsson, A.3
-
26
-
-
80051921186
-
Clinical potential and challenges of using genetically modified cells for articular cartilage repair
-
Madry H, Cucchiarini M. Clinical potential and challenges of using genetically modified cells for articular cartilage repair. Croat Med J 2011; 52: 245-261.
-
(2011)
Croat Med J
, vol.52
, pp. 245-261
-
-
Madry, H.1
Cucchiarini, M.2
-
27
-
-
29744465669
-
Gene therapy for cartilage defects
-
Cucchiarini M, Madry H. Gene therapy for cartilage defects. J Gene Med 2005; 7: 1495-1509.
-
(2005)
J Gene Med
, vol.7
, pp. 1495-1509
-
-
Cucchiarini, M.1
Madry, H.2
-
28
-
-
84867858047
-
Failed cartilage repair for early osteoarthritis defects: a biochemical, histological and immunohistochemical analysis of the repair tissue after treatment with marrow-stimulation techniques
-
Kaul G, Cucchiarini M, Remberger K, et al. Failed cartilage repair for early osteoarthritis defects: a biochemical, histological and immunohistochemical analysis of the repair tissue after treatment with marrow-stimulation techniques. Knee Surg Sports Traumatol Arthrosc 2012; 20: 2315-2324.
-
(2012)
Knee Surg Sports Traumatol Arthrosc
, vol.20
, pp. 2315-2324
-
-
Kaul, G.1
Cucchiarini, M.2
Remberger, K.3
-
30
-
-
0016819815
-
Maturation of the adrenal medulla-IV. Effects of morphine
-
Anderson TR, Slotkin TA. Maturation of the adrenal medulla-IV. Effects of morphine. Biochem Pharmacol 1975; 24: 1469-1474.
-
(1975)
Biochem Pharmacol
, vol.24
, pp. 1469-1474
-
-
Anderson, T.R.1
Slotkin, T.A.2
-
31
-
-
0035915777
-
Direct adenovirus-mediated insulin-like growth factor I gene transfer enhances transplant chondrocyte function
-
Brower-Toland BD, Saxer RA, Goodrich LR, et al. Direct adenovirus-mediated insulin-like growth factor I gene transfer enhances transplant chondrocyte function. Hum Gene Ther 2001; 12: 117-129.
-
(2001)
Hum Gene Ther
, vol.12
, pp. 117-129
-
-
Brower-Toland, B.D.1
Saxer, R.A.2
Goodrich, L.R.3
-
32
-
-
0033925453
-
Adhesion of transplanted chondrocytes onto cartilage in vitro and in vivo
-
Doherty PJ, Zhang H, Manolopoulos V, et al. Adhesion of transplanted chondrocytes onto cartilage in vitro and in vivo. J Rheumatol 2000; 27: 1725-1731.
-
(2000)
J Rheumatol
, vol.27
, pp. 1725-1731
-
-
Doherty, P.J.1
Zhang, H.2
Manolopoulos, V.3
-
33
-
-
0032076306
-
Resurfacing of articular cartilage explants with genetically modified human chondrocytes in vitro
-
Doherty PJ, Zhang H, Tremblay L, et al. Resurfacing of articular cartilage explants with genetically modified human chondrocytes in vitro. Osteoarthritis Cartilage 1998; 6: 153-159.
-
(1998)
Osteoarthritis Cartilage
, vol.6
, pp. 153-159
-
-
Doherty, P.J.1
Zhang, H.2
Tremblay, L.3
-
35
-
-
0033862014
-
Gene therapy for meniscal injury: enhanced synthesis of proteoglycan and collagen by meniscal cells transduced with a TGFbeta(1)gene
-
Goto H, Shuler FD, Niyibizi C, et al. Gene therapy for meniscal injury: enhanced synthesis of proteoglycan and collagen by meniscal cells transduced with a TGFbeta(1)gene. Osteoarthritis Cartilage 2000; 8: 266-271.
-
(2000)
Osteoarthritis Cartilage
, vol.8
, pp. 266-271
-
-
Goto, H.1
Shuler, F.D.2
Niyibizi, C.3
-
36
-
-
0036226899
-
In vivo gene delivery to synovium by lentiviral vectors
-
Gouze E, Pawliuk R, Pilapil C, et al. In vivo gene delivery to synovium by lentiviral vectors. Mol Ther 2002; 5: 397-404.
-
(2002)
Mol Ther
, vol.5
, pp. 397-404
-
-
Gouze, E.1
Pawliuk, R.2
Pilapil, C.3
-
37
-
-
2342505985
-
A comparative study of the inhibitory effects of interleukin-1 receptor antagonist following administration as a recombinant protein or by gene transfer
-
Gouze JN, Gouze E, Palmer GD, et al. A comparative study of the inhibitory effects of interleukin-1 receptor antagonist following administration as a recombinant protein or by gene transfer. Arthritis Res Ther 2003; 5: R301-R309.
-
(2003)
Arthritis Res Ther
, vol.5
-
-
Gouze, J.N.1
Gouze, E.2
Palmer, G.D.3
-
38
-
-
0033016094
-
Early expression of marker genes in the rabbit medial collateral and anterior cruciate ligaments: the use of different viral vectors and the effects of injury
-
Hildebrand KA, Deie M, Allen CR, et al. Early expression of marker genes in the rabbit medial collateral and anterior cruciate ligaments: the use of different viral vectors and the effects of injury. J Orthop Res 1999; 17: 37-42.
-
(1999)
J Orthop Res
, vol.17
, pp. 37-42
-
-
Hildebrand, K.A.1
Deie, M.2
Allen, C.R.3
-
39
-
-
8444233948
-
The combination of SOX5, SOX6, and SOX9 (the SOX trio) provides signals sufficient for induction of permanent cartilage
-
Ikeda T, Kamekura S, Mabuchi A, et al. The combination of SOX5, SOX6, and SOX9 (the SOX trio) provides signals sufficient for induction of permanent cartilage. Arthritis Rheum 2004; 50: 3561-3573.
-
(2004)
Arthritis Rheum
, vol.50
, pp. 3561-3573
-
-
Ikeda, T.1
Kamekura, S.2
Mabuchi, A.3
-
40
-
-
2342511482
-
Transduction of passaged human articular chondrocytes with adenoviral, retroviral, and lentiviral vectors and the effects of enhanced expression of SOX9
-
Li Y, Tew SR, Russell AM, et al. Transduction of passaged human articular chondrocytes with adenoviral, retroviral, and lentiviral vectors and the effects of enhanced expression of SOX9. Tissue Eng 2004; 10: 575-584.
-
(2004)
Tissue Eng
, vol.10
, pp. 575-584
-
-
Li, Y.1
Tew, S.R.2
Russell, A.M.3
-
41
-
-
4644244444
-
Overexpression of human fibroblast growth factor 2 stimulates cell proliferation in an ex vivo model of articular chondrocyte transplantation
-
Madry H, Emkey G, Zurakowski D, et al. Overexpression of human fibroblast growth factor 2 stimulates cell proliferation in an ex vivo model of articular chondrocyte transplantation. J Gene Med 2004; 6: 238-245.
-
(2004)
J Gene Med
, vol.6
, pp. 238-245
-
-
Madry, H.1
Emkey, G.2
Zurakowski, D.3
-
42
-
-
0034782732
-
Overexpression of human insulin-like growth factor-I promotes new tissue formation in an ex vivo model of articular chondrocyte transplantation
-
Madry H, Zurakowski D, Trippel SB. Overexpression of human insulin-like growth factor-I promotes new tissue formation in an ex vivo model of articular chondrocyte transplantation. Gene Ther 2001; 8: 1443-1449.
-
(2001)
Gene Ther
, vol.8
, pp. 1443-1449
-
-
Madry, H.1
Zurakowski, D.2
Trippel, S.B.3
-
43
-
-
0033779509
-
Cartilage and bone regeneration using gene-enhanced tissue engineering
-
Mason JM, Breitbart AS, Barcia M, et al. Cartilage and bone regeneration using gene-enhanced tissue engineering. Clin Orthop Relat Res 2000; 379(Suppl): S171-S178.
-
(2000)
Clin Orthop Relat Res
, vol.379
, Issue.SUPPL
-
-
Mason, J.M.1
Breitbart, A.S.2
Barcia, M.3
-
44
-
-
0029874283
-
Direct gene delivery to synovium. An evaluation of potential vectors in vitro and in vivo
-
Nita I, Ghivizzani SC, Galea-Lauri J, et al. Direct gene delivery to synovium. An evaluation of potential vectors in vitro and in vivo. Arthritis Rheum 1996; 39: 820-828.
-
(1996)
Arthritis Rheum
, vol.39
, pp. 820-828
-
-
Nita, I.1
Ghivizzani, S.C.2
Galea-Lauri, J.3
-
45
-
-
13244269894
-
Gene-mediated restoration of cartilage matrix by combination insulin-like growth factor-I/interleukin-1 receptor antagonist therapy
-
Nixon AJ, Haupt JL, Frisbie DD, et al. Gene-mediated restoration of cartilage matrix by combination insulin-like growth factor-I/interleukin-1 receptor antagonist therapy. Gene Ther 2005; 12: 177-186.
-
(2005)
Gene Ther
, vol.12
, pp. 177-186
-
-
Nixon, A.J.1
Haupt, J.L.2
Frisbie, D.D.3
-
46
-
-
0030961873
-
In vivo suppression of early experimental osteoarthritis by interleukin-1 receptor antagonist using gene therapy
-
Pelletier JP, Caron JP, Evans C, et al. In vivo suppression of early experimental osteoarthritis by interleukin-1 receptor antagonist using gene therapy. Arthritis Rheum 1997; 40: 1012-1019.
-
(1997)
Arthritis Rheum
, vol.40
, pp. 1012-1019
-
-
Pelletier, J.P.1
Caron, J.P.2
Evans, C.3
-
47
-
-
0037423736
-
Chondrogenesis enhanced by overexpression of sox9 gene in mouse bone marrow-derived mesenchymal stem cells
-
Tsuchiya H, Kitoh H, Sugiura F, et al. Chondrogenesis enhanced by overexpression of sox9 gene in mouse bone marrow-derived mesenchymal stem cells. Biochem Biophys Res Commun 2003; 301: 338-343.
-
(2003)
Biochem Biophys Res Commun
, vol.301
, pp. 338-343
-
-
Tsuchiya, H.1
Kitoh, H.2
Sugiura, F.3
-
48
-
-
70449529723
-
Treating human meniscal fibrochondrocytes with hIGF-1 gene by liposome
-
Zhang HN, Leng P, Wang YZ, et al. Treating human meniscal fibrochondrocytes with hIGF-1 gene by liposome. Clin Orthop Relat Res 2009; 467: 3175-3182.
-
(2009)
Clin Orthop Relat Res
, vol.467
, pp. 3175-3182
-
-
Zhang, H.N.1
Leng, P.2
Wang, Y.Z.3
-
49
-
-
2942555576
-
Suppression of early experimental osteoarthritis by gene transfer of interleukin-1 receptor antagonist and interleukin-10
-
Zhang X, Mao Z, Yu C. Suppression of early experimental osteoarthritis by gene transfer of interleukin-1 receptor antagonist and interleukin-10. J Orthop Res 2004; 22: 742-750.
-
(2004)
J Orthop Res
, vol.22
, pp. 742-750
-
-
Zhang, X.1
Mao, Z.2
Yu, C.3
-
50
-
-
0343618533
-
Empirical advantages of adeno-associated viral vectors in vivo gene therapy for arthritis
-
Goater J, Muller R, Kollias G, et al. Empirical advantages of adeno-associated viral vectors in vivo gene therapy for arthritis. J Rheumatol 2000; 27: 983-989.
-
(2000)
J Rheumatol
, vol.27
, pp. 983-989
-
-
Goater, J.1
Muller, R.2
Kollias, G.3
-
51
-
-
1642514749
-
Light-activated gene transduction of recombinant adeno-associated virus in human mesenchymal stem cells
-
Ito H, Goater JJ, Tiyapatanaputi P, et al. Light-activated gene transduction of recombinant adeno-associated virus in human mesenchymal stem cells. Gene Ther 2004; 11: 34-41.
-
(2004)
Gene Ther
, vol.11
, pp. 34-41
-
-
Ito, H.1
Goater, J.J.2
Tiyapatanaputi, P.3
-
52
-
-
20144387650
-
Remodelling of cortical bone allografts mediated by adherent rAAV-RANKL and VEGF gene therapy
-
Ito H, Koefoed M, Tiyapatanaputi P, et al. Remodelling of cortical bone allografts mediated by adherent rAAV-RANKL and VEGF gene therapy. Nat Med 2005; 11: 291-297.
-
(2005)
Nat Med
, vol.11
, pp. 291-297
-
-
Ito, H.1
Koefoed, M.2
Tiyapatanaputi, P.3
-
53
-
-
34248181957
-
Adeno-associated viral gene transfer of transforming growth factor-beta1 to human mesenchymal stem cells improves cartilage repair
-
Pagnotto MR, Wang Z, Karpie JC, et al. Adeno-associated viral gene transfer of transforming growth factor-beta1 to human mesenchymal stem cells improves cartilage repair. Gene Ther 2007; 14: 804-813.
-
(2007)
Gene Ther
, vol.14
, pp. 804-813
-
-
Pagnotto, M.R.1
Wang, Z.2
Karpie, J.C.3
-
54
-
-
34249987137
-
Adeno-associated viral vector transduction of human mesenchymal stem cells
-
Stender S, Murphy M, O'Brien T, et al. Adeno-associated viral vector transduction of human mesenchymal stem cells. Eur Cell Mater 2007; 13: 93-99.
-
(2007)
Eur Cell Mater
, vol.13
, pp. 93-99
-
-
Stender, S.1
Murphy, M.2
O'Brien, T.3
-
55
-
-
28444460380
-
Adeno-associated vector mediated gene transfer of transforming growth factor-beta1 to normal and osteoarthritic human chondrocytes stimulates cartilage anabolism
-
Ulrich-Vinther M, Stengaard C, Schwarz EM, et al. Adeno-associated vector mediated gene transfer of transforming growth factor-beta1 to normal and osteoarthritic human chondrocytes stimulates cartilage anabolism. Eur Cell Mater 2005; 10: 40-50.
-
(2005)
Eur Cell Mater
, vol.10
, pp. 40-50
-
-
Ulrich-Vinther, M.1
Stengaard, C.2
Schwarz, E.M.3
-
56
-
-
84864767326
-
SOX9 gene transfer via safe, stable, replication-defective recombinant adeno-associated virus vectors as a novel, powerful tool to enhance the chondrogenic potential of human mesenchymal stem cells
-
Venkatesan JK, Ekici M, Madry H, et al. SOX9 gene transfer via safe, stable, replication-defective recombinant adeno-associated virus vectors as a novel, powerful tool to enhance the chondrogenic potential of human mesenchymal stem cells. Stem Cell Res Ther 2012; 3: 22-36.
-
(2012)
Stem Cell Res Ther
, vol.3
, pp. 22-36
-
-
Venkatesan, J.K.1
Ekici, M.2
Madry, H.3
-
57
-
-
9244245810
-
Menisci are efficiently transduced by recombinant adeno-associated virus vectors in vitro and in vivo
-
Madry H, Cucchiarini M, Kaul G, et al. Menisci are efficiently transduced by recombinant adeno-associated virus vectors in vitro and in vivo. Am J Sports Med 2004; 32: 1860-1865.
-
(2004)
Am J Sports Med
, vol.32
, pp. 1860-1865
-
-
Madry, H.1
Cucchiarini, M.2
Kaul, G.3
-
58
-
-
84885901252
-
Recombinant adeno-associated virus vectors efficiently transduce human menisci
-
Madry H, Cucchiarini M, Kohn D, et al. Recombinant adeno-associated virus vectors efficiently transduce human menisci. Trans Orthop Res Soc 2002; 48: 0274.
-
(2002)
Trans Orthop Res Soc
, vol.48
, pp. 0274
-
-
Madry, H.1
Cucchiarini, M.2
Kohn, D.3
-
59
-
-
79960793071
-
Metabolic activities and chondrogenic differentiation of human mesenchymal stem cells following recombinant adeno-associated virus-mediated gene transfer and overexpression of fibroblast growth factor 2
-
Cucchiarini M, Ekici M, Schetting S, et al. Metabolic activities and chondrogenic differentiation of human mesenchymal stem cells following recombinant adeno-associated virus-mediated gene transfer and overexpression of fibroblast growth factor 2. Tissue Eng Part A 2011; 17: 1921-1933.
-
(2011)
Tissue Eng Part A
, vol.17
, pp. 1921-1933
-
-
Cucchiarini, M.1
Ekici, M.2
Schetting, S.3
-
60
-
-
70449720789
-
rAAV-mediated overexpression of FGF-2 promotes cell proliferation, survival, and alpha-SMA expression in human meniscal lesions
-
Cucchiarini M, Schetting S, Terwilliger EF, et al. rAAV-mediated overexpression of FGF-2 promotes cell proliferation, survival, and alpha-SMA expression in human meniscal lesions. Gene Ther 2009; 16: 1363-1372.
-
(2009)
Gene Ther
, vol.16
, pp. 1363-1372
-
-
Cucchiarini, M.1
Schetting, S.2
Terwilliger, E.F.3
-
61
-
-
22644436809
-
Improved tissue repair in articular cartilage defects in vivo by rAAV-mediated overexpression of human fibroblast growth factor 2
-
Cucchiarini M, Madry H, Ma C, et al. Improved tissue repair in articular cartilage defects in vivo by rAAV-mediated overexpression of human fibroblast growth factor 2. Mol Ther 2005; 12: 229-238.
-
(2005)
Mol Ther
, vol.12
, pp. 229-238
-
-
Cucchiarini, M.1
Madry, H.2
Ma, C.3
-
62
-
-
31644440253
-
Local stimulation of articular cartilage repair by transplantation of encapsulated chondrocytes overexpressing human fibroblast growth factor 2 (FGF-2) in vivo
-
Kaul G, Cucchiarini M, Arntzen D, et al. Local stimulation of articular cartilage repair by transplantation of encapsulated chondrocytes overexpressing human fibroblast growth factor 2 (FGF-2) in vivo. J Gene Med 2006; 8: 100-111.
-
(2006)
J Gene Med
, vol.8
, pp. 100-111
-
-
Kaul, G.1
Cucchiarini, M.2
Arntzen, D.3
-
63
-
-
22944436822
-
Stimulation of chondrocytes in vitro by gene transfer with plasmids coding for epidermal growth factor (hEGF) and basic fibroblast growth factor (bFGF)
-
Schmal H, Mehlhorn AT, Zwingmann J, et al. Stimulation of chondrocytes in vitro by gene transfer with plasmids coding for epidermal growth factor (hEGF) and basic fibroblast growth factor (bFGF). Cytotherapy 2005; 7: 292-300.
-
(2005)
Cytotherapy
, vol.7
, pp. 292-300
-
-
Schmal, H.1
Mehlhorn, A.T.2
Zwingmann, J.3
-
64
-
-
0036187950
-
Increased life span of human osteoarthritic chondrocytes by exogenous expression of telomerase
-
Piera-Velazquez S, Jimenez SA, Stokes D. Increased life span of human osteoarthritic chondrocytes by exogenous expression of telomerase. Arthritis Rheum 2002; 46: 683-693.
-
(2002)
Arthritis Rheum
, vol.46
, pp. 683-693
-
-
Piera-Velazquez, S.1
Jimenez, S.A.2
Stokes, D.3
-
65
-
-
84873693621
-
Growth factor transgenes interactively regulate articular chondrocytes
-
Shi S, Mercer S, Eckert GJ, et al. Growth factor transgenes interactively regulate articular chondrocytes. J Cell Biochem 2012; 114: 908-919.
-
(2012)
J Cell Biochem
, vol.114
, pp. 908-919
-
-
Shi, S.1
Mercer, S.2
Eckert, G.J.3
-
66
-
-
33845764391
-
Anti-apoptotic Bcl-2 gene transfection of human articular chondrocytes protects against nitric oxide-induced apoptosis
-
Surendran S, Kim SH, Jee BK, et al. Anti-apoptotic Bcl-2 gene transfection of human articular chondrocytes protects against nitric oxide-induced apoptosis. J Bone Joint Surg Br 2006; 88: 1660-1665.
-
(2006)
J Bone Joint Surg Br
, vol.88
, pp. 1660-1665
-
-
Surendran, S.1
Kim, S.H.2
Jee, B.K.3
-
67
-
-
30744436362
-
Gene transfer with HSP 70 in rat chondrocytes confers cytoprotection in vitro and during experimental osteoarthritis
-
Grossin L, Cournil-Henrionnet C, Pinzano A, et al. Gene transfer with HSP 70 in rat chondrocytes confers cytoprotection in vitro and during experimental osteoarthritis. FASEB J 2006; 20: 65-75.
-
(2006)
FASEB J
, vol.20
, pp. 65-75
-
-
Grossin, L.1
Cournil-Henrionnet, C.2
Pinzano, A.3
-
68
-
-
34347239641
-
Recombinant adeno-associated virus vector hybrids efficiently target different skeletal cells
-
Dai J, Rabie AB. Recombinant adeno-associated virus vector hybrids efficiently target different skeletal cells. Front Biosci 2007; 12: 4280-4287.
-
(2007)
Front Biosci
, vol.12
, pp. 4280-4287
-
-
Dai, J.1
Rabie, A.B.2
-
69
-
-
33749587067
-
Adenoviral gene transfer into osteoarthritis synovial cells using the endogenous inhibitor IkappaBalpha reveals that most, but not all, inflammatory and destructive mediators are NFkappaB dependent
-
Amos N, Lauder S, Evans A, et al. Adenoviral gene transfer into osteoarthritis synovial cells using the endogenous inhibitor IkappaBalpha reveals that most, but not all, inflammatory and destructive mediators are NFkappaB dependent. Rheumatology (Oxford) 2006; 45: 1201-1209.
-
(2006)
Rheumatology (Oxford)
, vol.45
, pp. 1201-1209
-
-
Amos, N.1
Lauder, S.2
Evans, A.3
-
70
-
-
79959502791
-
Elevated Dickkopf-2 levels contribute to the abnormal phenotype of human osteoarthritic osteoblasts
-
Chan TF, Couchourel D, Abed E, et al. Elevated Dickkopf-2 levels contribute to the abnormal phenotype of human osteoarthritic osteoblasts. J Bone Miner Res 2011; 26: 1399-1410.
-
(2011)
J Bone Miner Res
, vol.26
, pp. 1399-1410
-
-
Chan, T.F.1
Couchourel, D.2
Abed, E.3
-
71
-
-
84864470588
-
Dkk-1 expression in chondrocytes inhibits experimental osteoarthritic cartilage destruction in mice
-
Oh H, Chun CH, Chun JS. Dkk-1 expression in chondrocytes inhibits experimental osteoarthritic cartilage destruction in mice. Arthritis Rheum 2012; 64: 2568-2578.
-
(2012)
Arthritis Rheum
, vol.64
, pp. 2568-2578
-
-
Oh, H.1
Chun, C.H.2
Chun, J.S.3
-
72
-
-
84859517028
-
alpha-Catenin inhibits beta-catenin-T-cell factor/lymphoid enhancing factor transcriptional activity and collagen type II expression in articular chondrocytes through formation of Gli3R.alpha-catenin.beta-catenin ternary complex
-
Rhee J, Ryu JH, Kim JH, et al. alpha-Catenin inhibits beta-catenin-T-cell factor/lymphoid enhancing factor transcriptional activity and collagen type II expression in articular chondrocytes through formation of Gli3R.alpha-catenin.beta-catenin ternary complex. J Biol Chem 2012; 287: 11751-11760.
-
(2012)
J Biol Chem
, vol.287
, pp. 11751-11760
-
-
Rhee, J.1
Ryu, J.H.2
Kim, J.H.3
-
73
-
-
11144240780
-
Stimulation of proteoglycan synthesis by glucuronosyltransferase-I gene delivery: a strategy to promote cartilage repair
-
Venkatesan N, Barre L, Benani A, et al. Stimulation of proteoglycan synthesis by glucuronosyltransferase-I gene delivery: a strategy to promote cartilage repair. Proc Natl Acad Sci U S A 2004; 101: 18087-18092.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 18087-18092
-
-
Venkatesan, N.1
Barre, L.2
Benani, A.3
-
74
-
-
0035915777
-
Direct adenovirus-mediated insulin-like growth factor I gene transfer enhances transplant chondrocyte function
-
Brower-Toland BD, Saxer RA, Goodrich LR, et al. Direct adenovirus-mediated insulin-like growth factor I gene transfer enhances transplant chondrocyte function. Hum Gene Ther 2001; 12: 117-129.
-
(2001)
Hum Gene Ther
, vol.12
, pp. 117-129
-
-
Brower-Toland, B.D.1
Saxer, R.A.2
Goodrich, L.R.3
-
75
-
-
78149265290
-
Effects of adenovirus-mediated bFGF, IL-1Ra and IGF-1 gene transfer on human osteoarthritic chondrocytes and osteoarthritis in rabbits
-
Chen B, Qin J, Wang H, et al. Effects of adenovirus-mediated bFGF, IL-1Ra and IGF-1 gene transfer on human osteoarthritic chondrocytes and osteoarthritis in rabbits. Exp Mol Med 2010; 42: 684-695.
-
(2010)
Exp Mol Med
, vol.42
, pp. 684-695
-
-
Chen, B.1
Qin, J.2
Wang, H.3
-
76
-
-
11044221899
-
Dual transduction of insulin-like growth factor-I and interleukin-1 receptor antagonist protein controls cartilage degradation in an osteoarthritic culture model
-
Haupt JL, Frisbie DD, McIlwraith CW, et al. Dual transduction of insulin-like growth factor-I and interleukin-1 receptor antagonist protein controls cartilage degradation in an osteoarthritic culture model. J Orthop Res 2005; 23: 118-126.
-
(2005)
J Orthop Res
, vol.23
, pp. 118-126
-
-
Haupt, J.L.1
Frisbie, D.D.2
McIlwraith, C.W.3
-
77
-
-
20244375123
-
Continuous transforming growth factor beta1 secretion by cell-mediated gene therapy maintains chondrocyte redifferentiation
-
Lee DK, Choi KB, Oh IS, et al. Continuous transforming growth factor beta1 secretion by cell-mediated gene therapy maintains chondrocyte redifferentiation. Tissue Eng 2005; 11: 310-318.
-
(2005)
Tissue Eng
, vol.11
, pp. 310-318
-
-
Lee, D.K.1
Choi, K.B.2
Oh, I.S.3
-
78
-
-
4644244444
-
Overexpression of human fibroblast growth factor 2 stimulates cell proliferation in an ex vivo model of articular chondrocyte transplantation
-
Madry H, Emkey G, Zurakowski D, et al. Overexpression of human fibroblast growth factor 2 stimulates cell proliferation in an ex vivo model of articular chondrocyte transplantation. J Gene Med 2004; 6: 238-245.
-
(2004)
J Gene Med
, vol.6
, pp. 238-245
-
-
Madry, H.1
Emkey, G.2
Zurakowski, D.3
-
79
-
-
0035036445
-
Efficacy of cationic-liposome mediated gene transfer to mesangial cells in vitro and in vivo
-
Madry H, Reszka R, Bohlender J, et al. Efficacy of cationic-liposome mediated gene transfer to mesangial cells in vitro and in vivo. J Mol Med 2001; 79: 184-189.
-
(2001)
J Mol Med
, vol.79
, pp. 184-189
-
-
Madry, H.1
Reszka, R.2
Bohlender, J.3
-
80
-
-
0033779712
-
Insulin-like growth factor-I gene therapy applications for cartilage repair
-
Nixon AJ, Brower-Toland BD, Bent SJ, et al. Insulin-like growth factor-I gene therapy applications for cartilage repair. Clin Orthop Relat Res 2000; 43: S201-213.
-
(2000)
Clin Orthop Relat Res
, vol.43
-
-
Nixon, A.J.1
Brower-Toland, B.D.2
Bent, S.J.3
-
81
-
-
0034871638
-
Gene mediated insulin-like growth factor-I delivery to the synovium
-
Saxer RA, Bent SJ, Brower-Toland BD, et al. Gene mediated insulin-like growth factor-I delivery to the synovium. J Orthop Res 2001; 19: 759-767.
-
(2001)
J Orthop Res
, vol.19
, pp. 759-767
-
-
Saxer, R.A.1
Bent, S.J.2
Brower-Toland, B.D.3
-
82
-
-
0034232660
-
Increased matrix synthesis following adenoviral transfer of a transforming growth factor beta1 gene into articular chondrocytes
-
Shuler FD, Georgescu HI, Niyibizi C, et al. Increased matrix synthesis following adenoviral transfer of a transforming growth factor beta1 gene into articular chondrocytes. J Orthop Res 2000; 18: 585-592.
-
(2000)
J Orthop Res
, vol.18
, pp. 585-592
-
-
Shuler, F.D.1
Georgescu, H.I.2
Niyibizi, C.3
-
83
-
-
0034091315
-
Genetic enhancement of matrix synthesis by articular chondrocytes
-
Smith P, Shuler FD, Georgescu HI, et al. Genetic enhancement of matrix synthesis by articular chondrocytes. J Rheumatol 2000; 43: 1156-1164.
-
(2000)
J Rheumatol
, vol.43
, pp. 1156-1164
-
-
Smith, P.1
Shuler, F.D.2
Georgescu, H.I.3
-
84
-
-
28444460380
-
Adeno-associated vector mediated gene transfer of transforming growth factor-beta1 to normal and osteoarthritic human chondrocytes stimulates cartilage anabolism
-
Ulrich-Vinther M, Stengaard C, Schwarz EM, et al. Adeno-associated vector mediated gene transfer of transforming growth factor-beta1 to normal and osteoarthritic human chondrocytes stimulates cartilage anabolism. Eur Cell Mater 2005; 10: 40-59.
-
(2005)
Eur Cell Mater
, vol.10
, pp. 40-59
-
-
Ulrich-Vinther, M.1
Stengaard, C.2
Schwarz, E.M.3
-
85
-
-
0033763544
-
Adenovirus-mediated gene transfer of insulin-like growth factor 1 stimulates proteoglycan synthesis in rabbit joints
-
Mi Z, Ghivizzani SC, Lechman ER, et al. Adenovirus-mediated gene transfer of insulin-like growth factor 1 stimulates proteoglycan synthesis in rabbit joints. Arthritis Rheum 2000; 43: 2563-2570.
-
(2000)
Arthritis Rheum
, vol.43
, pp. 2563-2570
-
-
Mi, Z.1
Ghivizzani, S.C.2
Lechman, E.R.3
-
86
-
-
22644444720
-
Gene-induced chondrogenesis of primary mesenchymal stem cells in vitro
-
Palmer GD, Steinert A, Pascher A, et al. Gene-induced chondrogenesis of primary mesenchymal stem cells in vitro. Mol Ther 2005; 12: 219-228.
-
(2005)
Mol Ther
, vol.12
, pp. 219-228
-
-
Palmer, G.D.1
Steinert, A.2
Pascher, A.3
-
87
-
-
84861098549
-
Regulation of articular chondrocyte aggrecan and collagen gene expression by multiple growth factor gene transfer
-
Shi S, Mercer S, Eckert GJ, et al. Regulation of articular chondrocyte aggrecan and collagen gene expression by multiple growth factor gene transfer. J Orthop Res 2011; 30: 1026-1031.
-
(2011)
J Orthop Res
, vol.30
, pp. 1026-1031
-
-
Shi, S.1
Mercer, S.2
Eckert, G.J.3
-
88
-
-
12144276564
-
Retroviral transduction with SOX9 enhances re-expression of the chondrocyte phenotype in passaged osteoarthritic human articular chondrocytes
-
Tew SR, Li Y, Pothacharoen P, et al. Retroviral transduction with SOX9 enhances re-expression of the chondrocyte phenotype in passaged osteoarthritic human articular chondrocytes. Osteoarthritis Cartilage 2005; 13: 80-89.
-
(2005)
Osteoarthritis Cartilage
, vol.13
, pp. 80-89
-
-
Tew, S.R.1
Li, Y.2
Pothacharoen, P.3
-
89
-
-
0037423736
-
Chondrogenesis enhanced by overexpression of sox9 gene in mouse bone marrow-derived mesenchymal stem cells
-
Tsuchiya H, Kitoh H, Sugiura F, et al. Chondrogenesis enhanced by overexpression of sox9 gene in mouse bone marrow-derived mesenchymal stem cells. Biochem Biophys Res Commun 2003; 301: 338-343.
-
(2003)
Biochem Biophys Res Commun
, vol.301
, pp. 338-343
-
-
Tsuchiya, H.1
Kitoh, H.2
Sugiura, F.3
-
90
-
-
84855750914
-
SOX trio-co-transduced adipose stem cells in fibrin gel to enhance cartilage repair and delay the progression of osteoarthritis in the rat
-
Lee JM, Im GI. SOX trio-co-transduced adipose stem cells in fibrin gel to enhance cartilage repair and delay the progression of osteoarthritis in the rat. Biomaterials 2012; 33: 2016-2024.
-
(2012)
Biomaterials
, vol.33
, pp. 2016-2024
-
-
Lee, J.M.1
Im, G.I.2
-
91
-
-
84862877054
-
Molecular mechanism of hypoxia-induced chondrogenesis and its application in in vivo cartilage tissue engineering
-
Duval E, Bauge C, Andriamanalijaona R, et al. Molecular mechanism of hypoxia-induced chondrogenesis and its application in in vivo cartilage tissue engineering. Biomaterials 2012; 33: 6042-6051.
-
(2012)
Biomaterials
, vol.33
, pp. 6042-6051
-
-
Duval, E.1
Bauge, C.2
Andriamanalijaona, R.3
-
92
-
-
61849173539
-
The identification of differentially expressed microRNA in osteoarthritic tissue that modulate the production of TNF-alpha and MMP13
-
Jones SW, Watkins G, Le Good N, et al. The identification of differentially expressed microRNA in osteoarthritic tissue that modulate the production of TNF-alpha and MMP13. Osteoarthritis Cartilage 2009; 17: 464-472.
-
(2009)
Osteoarthritis Cartilage
, vol.17
, pp. 464-472
-
-
Jones, S.W.1
Watkins, G.2
Le Good, N.3
-
93
-
-
73649139221
-
Regulation of the IGFBP-5 and MMP-13 genes by the microRNAs miR-140 and miR-27a in human osteoarthritic chondrocytes
-
Tardif G, Hum D, Pelletier JP, et al. Regulation of the IGFBP-5 and MMP-13 genes by the microRNAs miR-140 and miR-27a in human osteoarthritic chondrocytes. BMC Musculoskelet Disord 2009; 10: 148-158.
-
(2009)
BMC Musculoskelet Disord
, vol.10
, pp. 148-158
-
-
Tardif, G.1
Hum, D.2
Pelletier, J.P.3
-
94
-
-
77953067173
-
MicroRNA-140 plays dual roles in both cartilage development and homeostasis
-
Miyaki S, Sato T, Inoue A, et al. MicroRNA-140 plays dual roles in both cartilage development and homeostasis. Genes Dev 2010; 24: 1173-1185.
-
(2010)
Genes Dev
, vol.24
, pp. 1173-1185
-
-
Miyaki, S.1
Sato, T.2
Inoue, A.3
-
95
-
-
77955283528
-
Type II collagen expression is regulated by tissue-specific miR-675 in human articular chondrocytes
-
Dudek KA, Lafont JE, Martinez-Sanchez A, et al. Type II collagen expression is regulated by tissue-specific miR-675 in human articular chondrocytes. J Biol Chem 2010; 285: 24381-24387.
-
(2010)
J Biol Chem
, vol.285
, pp. 24381-24387
-
-
Dudek, K.A.1
Lafont, J.E.2
Martinez-Sanchez, A.3
-
96
-
-
61349159991
-
Regulation of cartilage-specific gene expression in human chondrocytes by SirT1 and nicotinamide phosphoribosyltransferase
-
Dvir-Ginzberg M, Gagarina V, Lee EJ, et al. Regulation of cartilage-specific gene expression in human chondrocytes by SirT1 and nicotinamide phosphoribosyltransferase. J Biol Chem 2008; 283: 36300-36310.
-
(2008)
J Biol Chem
, vol.283
, pp. 36300-36310
-
-
Dvir-Ginzberg, M.1
Gagarina, V.2
Lee, E.J.3
-
97
-
-
20244384369
-
Inhibition of cartilage degradation: a combined tissue engineering and gene therapy approach
-
Kafienah W, Al-Fayez F, Hollander AP, et al. Inhibition of cartilage degradation: a combined tissue engineering and gene therapy approach. Arthritis Rheum 2003; 48: 709-718.
-
(2003)
Arthritis Rheum
, vol.48
, pp. 709-718
-
-
Kafienah, W.1
Al-Fayez, F.2
Hollander, A.P.3
-
98
-
-
0029133070
-
Inhibition of interleukin-1-induced effects in synoviocytes transduced with the human IL-1 receptor antagonist cDNA using an adenoviral vector
-
Roessler BJ, Hartman JW, Vallance DK, et al. Inhibition of interleukin-1-induced effects in synoviocytes transduced with the human IL-1 receptor antagonist cDNA using an adenoviral vector. Hum Gene Ther 1995; 6: 307-316.
-
(1995)
Hum Gene Ther
, vol.6
, pp. 307-316
-
-
Roessler, B.J.1
Hartman, J.W.2
Vallance, D.K.3
-
99
-
-
0028799826
-
Transplantation of transduced chondrocytes protects articular cartilage from interleukin 1-induced extracellular matrix degradation
-
Baragi VM, Renkiewicz RR, Jordan H, et al. Transplantation of transduced chondrocytes protects articular cartilage from interleukin 1-induced extracellular matrix degradation. J Clin Invest 1995; 96: 2454-2460.
-
(1995)
J Clin Invest
, vol.96
, pp. 2454-2460
-
-
Baragi, V.M.1
Renkiewicz, R.R.2
Jordan, H.3
-
100
-
-
30944445959
-
Direct chitosan-mediated gene delivery to the rabbit knee joints in vitro and in vivo
-
Zhang X, Yu C, Xu S, et al. Direct chitosan-mediated gene delivery to the rabbit knee joints in vitro and in vivo. Biochem Biophys Res Commun 2006; 341: 202-208.
-
(2006)
Biochem Biophys Res Commun
, vol.341
, pp. 202-208
-
-
Zhang, X.1
Yu, C.2
Xu, S.3
-
101
-
-
85047697321
-
Treatment of experimental equine osteoarthritis by in vivo delivery of the equine interleukin-1 receptor antagonist gene
-
Frisbie DD, Ghivizzani SC, Robbins PD, et al. Treatment of experimental equine osteoarthritis by in vivo delivery of the equine interleukin-1 receptor antagonist gene. Gene Ther 2002; 9: 12-20.
-
(2002)
Gene Ther
, vol.9
, pp. 12-20
-
-
Frisbie, D.D.1
Ghivizzani, S.C.2
Robbins, P.D.3
-
102
-
-
84878834158
-
Optimization of scAAVIL-1ra in vitro and in vivo to deliver high levels of therapeutic protein for treatment of osteoarthritis
-
Goodrich LR, Phillips JN, McIlwraith CW, et al. Optimization of scAAVIL-1ra in vitro and in vivo to deliver high levels of therapeutic protein for treatment of osteoarthritis. Mol Ther Nucleic Acids 2013; 2: e70-e79.
-
(2013)
Mol Ther Nucleic Acids
, vol.2
-
-
Goodrich, L.R.1
Phillips, J.N.2
McIlwraith, C.W.3
-
104
-
-
0035284837
-
Effective treatment of established murine collagen-induced arthritis by systemic administration of dendritic cells genetically modified to express IL-4
-
Kim SH, Kim S, Evans CH, et al. Effective treatment of established murine collagen-induced arthritis by systemic administration of dendritic cells genetically modified to express IL-4. J Immunol 2001; 166: 3499-3505.
-
(2001)
J Immunol
, vol.166
, pp. 3499-3505
-
-
Kim, S.H.1
Kim, S.2
Evans, C.H.3
-
105
-
-
0242606953
-
Adenoviral overexpression of Smad-7 and Smad-6 differentially regulates TGF-beta-mediated chondrocyte proliferation and proteoglycan synthesis
-
Scharstuhl A, Diepens R, Lensen J, et al. Adenoviral overexpression of Smad-7 and Smad-6 differentially regulates TGF-beta-mediated chondrocyte proliferation and proteoglycan synthesis. Osteoarthritis Cartilage 2003; 11: 773-782.
-
(2003)
Osteoarthritis Cartilage
, vol.11
, pp. 773-782
-
-
Scharstuhl, A.1
Diepens, R.2
Lensen, J.3
-
106
-
-
0032924502
-
In vivo transfer of interleukin-1 receptor antagonist gene in osteoarthritic rabbit knee joints: prevention of osteoarthritis progression
-
Fernandes J, Tardif G, Martel-Pelletier J, et al. In vivo transfer of interleukin-1 receptor antagonist gene in osteoarthritic rabbit knee joints: prevention of osteoarthritis progression. Am J Pathol 1999; 154: 1159-1169.
-
(1999)
Am J Pathol
, vol.154
, pp. 1159-1169
-
-
Fernandes, J.1
Tardif, G.2
Martel-Pelletier, J.3
-
107
-
-
77957201321
-
Intraarticular gene transfer of thrombospondin-1 suppresses the disease progression of experimental osteoarthritis
-
Hsieh JL, Shen PC, Shiau AL, et al. Intraarticular gene transfer of thrombospondin-1 suppresses the disease progression of experimental osteoarthritis. J Orthop Res 2010; 28: 1300-1306.
-
(2010)
J Orthop Res
, vol.28
, pp. 1300-1306
-
-
Hsieh, J.L.1
Shen, P.C.2
Shiau, A.L.3
-
108
-
-
66049129631
-
Cartilage repair in a rat model of osteoarthritis through intraarticular transplantation of muscle-derived stem cells expressing bone morphogenetic protein 4 and soluble Flt-1
-
Matsumoto T, Cooper GM, Gharaibeh B, et al. Cartilage repair in a rat model of osteoarthritis through intraarticular transplantation of muscle-derived stem cells expressing bone morphogenetic protein 4 and soluble Flt-1. Arthritis Rheum 2009; 60: 1390-1405.
-
(2009)
Arthritis Rheum
, vol.60
, pp. 1390-1405
-
-
Matsumoto, T.1
Cooper, G.M.2
Gharaibeh, B.3
-
109
-
-
84855750914
-
SOX trio-co-transduced adipose stem cells in fibrin gel to enhance cartilage repair and delay the progression of osteoarthritis in the rat
-
Lee JM, Im GI. SOX trio-co-transduced adipose stem cells in fibrin gel to enhance cartilage repair and delay the progression of osteoarthritis in the rat. Biomaterials 2011; 33: 2016-2024.
-
(2011)
Biomaterials
, vol.33
, pp. 2016-2024
-
-
Lee, J.M.1
Im, G.I.2
-
110
-
-
81155137913
-
Transplanted articular chondrocytes co-overexpressing IGF-I and FGF-2 stimulate cartilage repair in vivo
-
Orth P, Kaul G, Cucchiarini M, et al. Transplanted articular chondrocytes co-overexpressing IGF-I and FGF-2 stimulate cartilage repair in vivo. Knee Surg Sports Traumatol Arthrosc 2011; 19: 2119-2130.
-
(2011)
Knee Surg Sports Traumatol Arthrosc
, vol.19
, pp. 2119-2130
-
-
Orth, P.1
Kaul, G.2
Cucchiarini, M.3
-
111
-
-
84862778885
-
Co-delivery of SOX9 genes and anti-Cbfa-1 siRNA coated onto PLGA nanoparticles for chondrogenesis of human MSCs
-
Jeon SY, Park JS, Yang HN, et al. Co-delivery of SOX9 genes and anti-Cbfa-1 siRNA coated onto PLGA nanoparticles for chondrogenesis of human MSCs. Biomaterials 2012; 33: 4413-4423.
-
(2012)
Biomaterials
, vol.33
, pp. 4413-4423
-
-
Jeon, S.Y.1
Park, J.S.2
Yang, H.N.3
-
112
-
-
84941600568
-
Co-transduction of lentiviral and adenoviral vectors for co-delivery of growth factor and shRNA genes in mesenchymal stem cells-based chondrogenic system
-
doi:10.1002/term.1656.
-
Zhang F, Yao Y, Su K, et al. Co-transduction of lentiviral and adenoviral vectors for co-delivery of growth factor and shRNA genes in mesenchymal stem cells-based chondrogenic system. J Tissue Eng Regen Med 2012. doi:10.1002/term.1656.
-
(2012)
J Tissue Eng Regen Med
-
-
Zhang, F.1
Yao, Y.2
Su, K.3
-
114
-
-
0033994254
-
Efficient lipid-mediated gene transfer to articular chondrocytes
-
Madry H, Trippel SB. Efficient lipid-mediated gene transfer to articular chondrocytes. Gene Ther 2000; 7: 286-291.
-
(2000)
Gene Ther
, vol.7
, pp. 286-291
-
-
Madry, H.1
Trippel, S.B.2
-
115
-
-
84864317336
-
Effective, safe nonviral gene transfer to preserve the chondrogenic differentiation potential of human mesenchymal stem cells
-
Elsler S, Schetting S, Schmitt G, et al. Effective, safe nonviral gene transfer to preserve the chondrogenic differentiation potential of human mesenchymal stem cells. J Gene Med 2012; 14: 501-511.
-
(2012)
J Gene Med
, vol.14
, pp. 501-511
-
-
Elsler, S.1
Schetting, S.2
Schmitt, G.3
-
116
-
-
0031786744
-
Adenovirus mediated gene delivery to the joints of guinea pigs
-
Ikeda T, Kubo T, Arai Y, et al. Adenovirus mediated gene delivery to the joints of guinea pigs. J Rheumatol 1998; 25: 1666-1673.
-
(1998)
J Rheumatol
, vol.25
, pp. 1666-1673
-
-
Ikeda, T.1
Kubo, T.2
Arai, Y.3
-
117
-
-
0030823167
-
LacZ and interleukin-3 expression in vivo after retroviral transduction of marrow-derived human osteogenic mesenchymal progenitors
-
Allay JA, Dennis JE, Haynesworth SE, et al. LacZ and interleukin-3 expression in vivo after retroviral transduction of marrow-derived human osteogenic mesenchymal progenitors. Hum Gene Ther 1997; 8: 1417-1427.
-
(1997)
Hum Gene Ther
, vol.8
, pp. 1417-1427
-
-
Allay, J.A.1
Dennis, J.E.2
Haynesworth, S.E.3
-
118
-
-
0036226899
-
In vivo gene delivery to synovium by lentiviral vectors
-
Gouze E, Pawliuk R, Pilapil C, et al. In vivo gene delivery to synovium by lentiviral vectors. Mol Ther 2002; 5: 397-404.
-
(2002)
Mol Ther
, vol.5
, pp. 397-404
-
-
Gouze, E.1
Pawliuk, R.2
Pilapil, C.3
-
119
-
-
55049118090
-
Lentiviral-transduced human mesenchymal stem cells persistently express therapeutic levels of enzyme in a xenotransplantation model of human disease
-
Meyerrose TE, Roberts M, Ohlemiller KK, et al. Lentiviral-transduced human mesenchymal stem cells persistently express therapeutic levels of enzyme in a xenotransplantation model of human disease. Stem Cells 2008; 26: 1713-1722.
-
(2008)
Stem Cells
, vol.26
, pp. 1713-1722
-
-
Meyerrose, T.E.1
Roberts, M.2
Ohlemiller, K.K.3
-
120
-
-
34249987137
-
Adeno-associated viral vector transduction of human mesenchymal stem cells
-
Stender S, Murphy M, O'Brien T, et al. Adeno-associated viral vector transduction of human mesenchymal stem cells. Eur Cell Mater 2007; 13: 93-99.
-
(2007)
Eur Cell Mater
, vol.13
, pp. 93-99
-
-
Stender, S.1
Murphy, M.2
O'Brien, T.3
-
121
-
-
0034882826
-
Self-complementary recombinant adeno-associated virus (scAAV) vectors promote efficient transduction independently of DNA synthesis
-
McCarty DM, Monahan PE, Samulski RJ. Self-complementary recombinant adeno-associated virus (scAAV) vectors promote efficient transduction independently of DNA synthesis. Gene Ther 2001; 8: 1248-1254.
-
(2001)
Gene Ther
, vol.8
, pp. 1248-1254
-
-
McCarty, D.M.1
Monahan, P.E.2
Samulski, R.J.3
-
122
-
-
82955198421
-
Effective reduction of the interleukin-1beta transcript in osteoarthritis-prone guinea pig chondrocytes via short hairpin RNA mediated RNA interference influences gene expression of mediators implicated in disease pathogenesis
-
Santangelo KS, Bertone AL. Effective reduction of the interleukin-1beta transcript in osteoarthritis-prone guinea pig chondrocytes via short hairpin RNA mediated RNA interference influences gene expression of mediators implicated in disease pathogenesis. Osteoarthritis Cartilage 2011; 19: 1449-1457.
-
(2011)
Osteoarthritis Cartilage
, vol.19
, pp. 1449-1457
-
-
Santangelo, K.S.1
Bertone, A.L.2
-
123
-
-
84882288958
-
scAAV-mediated gene transfer of interleukin-1-receptor antagonist to synovium and articular cartilage in large mammalian joints
-
Watson RS, Broome TA, Levings PP, et al. scAAV-mediated gene transfer of interleukin-1-receptor antagonist to synovium and articular cartilage in large mammalian joints. Gene Ther 2013; 20: 670-677.
-
(2013)
Gene Ther
, vol.20
, pp. 670-677
-
-
Watson, R.S.1
Broome, T.A.2
Levings, P.P.3
-
124
-
-
84859440283
-
The AAV vector toolkit: poised at the clinical crossroads
-
Asokan A, Schaffer DV, Samulski RJ. The AAV vector toolkit: poised at the clinical crossroads. Mol Ther 2012; 20: 699-708.
-
(2012)
Mol Ther
, vol.20
, pp. 699-708
-
-
Asokan, A.1
Schaffer, D.V.2
Samulski, R.J.3
-
125
-
-
84857602982
-
Adeno-associated virus vectorology, manufacturing, and clinical applications
-
Grieger JC, Samulski RJ. Adeno-associated virus vectorology, manufacturing, and clinical applications. Methods Enzymol 2012; 507: 229-254.
-
(2012)
Methods Enzymol
, vol.507
, pp. 229-254
-
-
Grieger, J.C.1
Samulski, R.J.2
-
126
-
-
79954622209
-
Therapeutic in vivo gene transfer for genetic disease using AAV: progress and challenges
-
Mingozzi F, High KA. Therapeutic in vivo gene transfer for genetic disease using AAV: progress and challenges. Nat Rev Genet 2011; 12: 341-355.
-
(2011)
Nat Rev Genet
, vol.12
, pp. 341-355
-
-
Mingozzi, F.1
High, K.A.2
-
127
-
-
0033774634
-
Evaluation of gene therapy as a treatment for equine traumatic arthritis and osteoarthritis
-
Frisbie DD, McIlwraith CW. Evaluation of gene therapy as a treatment for equine traumatic arthritis and osteoarthritis. Clin Orthop Relat Res 2000; 379(Suppl): S273-S287.
-
(2000)
Clin Orthop Relat Res
, vol.379
, Issue.SUPPL
-
-
Frisbie, D.D.1
McIlwraith, C.W.2
-
128
-
-
84867863259
-
In vivo reduction or blockade of interleukin-1beta in primary osteoarthritis influences expression of mediators implicated in pathogenesis
-
Santangelo KS, Nuovo GJ, Bertone AL. In vivo reduction or blockade of interleukin-1beta in primary osteoarthritis influences expression of mediators implicated in pathogenesis. Osteoarthritis Cartilage 2012; 20: 1610-1618.
-
(2012)
Osteoarthritis Cartilage
, vol.20
, pp. 1610-1618
-
-
Santangelo, K.S.1
Nuovo, G.J.2
Bertone, A.L.3
-
129
-
-
38949205532
-
Suppression of early experimental osteoarthritis by in vivo delivery of the adenoviral vector-mediated NF-kappaBp65-specific siRNA
-
Chen LX, Lin L, Wang HJ, et al. Suppression of early experimental osteoarthritis by in vivo delivery of the adenoviral vector-mediated NF-kappaBp65-specific siRNA. Osteoarthritis Cartilage 2008; 16: 174-184.
-
(2008)
Osteoarthritis Cartilage
, vol.16
, pp. 174-184
-
-
Chen, L.X.1
Lin, L.2
Wang, H.J.3
-
130
-
-
79953199101
-
Inhibition of cartilage damage by pro-opiomelanocortin prohormone overexpression in a rat model of osteoarthritis
-
Shen PC, Shiau AL, Jou IM, et al. Inhibition of cartilage damage by pro-opiomelanocortin prohormone overexpression in a rat model of osteoarthritis. Exp Biol Med (Maywood) 2011; 236: 334-340.
-
(2011)
Exp Biol Med (Maywood)
, vol.236
, pp. 334-340
-
-
Shen, P.C.1
Shiau, A.L.2
Jou, I.M.3
-
131
-
-
70349795944
-
Transfection of rat cells with proopiomeranocortin gene, precursor of endogenous endorphin, using radial shock waves suppresses inflammatory pain
-
Yamashita M, Yamauchi K, Suzuki M, et al. Transfection of rat cells with proopiomeranocortin gene, precursor of endogenous endorphin, using radial shock waves suppresses inflammatory pain. Spine (Phila Pa 1976) 2009; 34: 2270-2277.
-
(2009)
Spine (Phila Pa 1976)
, vol.34
, pp. 2270-2277
-
-
Yamashita, M.1
Yamauchi, K.2
Suzuki, M.3
-
132
-
-
66549095444
-
TGF beta-induced cartilage repair is maintained but fibrosis is blocked in the presence of Smad7
-
Blaney Davidson EN, Vitters EL, van den Berg WB, et al. TGF beta-induced cartilage repair is maintained but fibrosis is blocked in the presence of Smad7. Arthritis Res Ther 2006; 8: R65-R72.
-
(2006)
Arthritis Res Ther
, vol.8
-
-
Blaney Davidson, E.N.1
Vitters, E.L.2
van den Berg, W.B.3
-
133
-
-
0346220031
-
Reduction of osteophyte formation and synovial thickening by adenoviral overexpression of transforming growth factor beta/bone morphogenetic protein inhibitors during experimental osteoarthritis
-
Scharstuhl A, Vitters EL, van der Kraan PM, et al. Reduction of osteophyte formation and synovial thickening by adenoviral overexpression of transforming growth factor beta/bone morphogenetic protein inhibitors during experimental osteoarthritis. Arthritis Rheum 2003; 48: 3442-3451.
-
(2003)
Arthritis Rheum
, vol.48
, pp. 3442-3451
-
-
Scharstuhl, A.1
Vitters, E.L.2
van der Kraan, P.M.3
-
134
-
-
58849111311
-
Adenovirus-mediated kallistatin gene transfer ameliorates disease progression in a rat model of osteoarthritis induced by anterior cruciate ligament transection
-
Hsieh JL, Shen PC, Shiau AL, et al. Adenovirus-mediated kallistatin gene transfer ameliorates disease progression in a rat model of osteoarthritis induced by anterior cruciate ligament transection. Hum Gene Ther 2009; 20: 147-158.
-
(2009)
Hum Gene Ther
, vol.20
, pp. 147-158
-
-
Hsieh, J.L.1
Shen, P.C.2
Shiau, A.L.3
-
135
-
-
0027435633
-
Intraarticular expression of biologically active interleukin 1-receptor-antagonist protein by ex vivo gene transfer
-
Bandara G, Mueller GM, Galea-Lauri J, et al. Intraarticular expression of biologically active interleukin 1-receptor-antagonist protein by ex vivo gene transfer. Proc Natl Acad Sci U S A 1993; 90: 10764-10768.
-
(1993)
Proc Natl Acad Sci U S A
, vol.90
, pp. 10764-10768
-
-
Bandara, G.1
Mueller, G.M.2
Galea-Lauri, J.3
-
136
-
-
2942555576
-
Suppression of early experimental osteoarthritis by gene transfer of interleukin-1 receptor antagonist and interleukin-10
-
Zhang X, Mao Z, Yu C. Suppression of early experimental osteoarthritis by gene transfer of interleukin-1 receptor antagonist and interleukin-10. J Orthop Res 2004; 22: 742-750.
-
(2004)
J Orthop Res
, vol.22
, pp. 742-750
-
-
Zhang, X.1
Mao, Z.2
Yu, C.3
-
138
-
-
19144364120
-
Clinical trial to assess the safety, feasibility, and efficacy of transferring a potentially anti-arthritic cytokine gene to human joints with rheumatoid arthritis
-
Evans CH, Robbins PD, Ghivizzani SC, et al. Clinical trial to assess the safety, feasibility, and efficacy of transferring a potentially anti-arthritic cytokine gene to human joints with rheumatoid arthritis. Hum Gene Ther 1996; 7: 1261-1280.
-
(1996)
Hum Gene Ther
, vol.7
, pp. 1261-1280
-
-
Evans, C.H.1
Robbins, P.D.2
Ghivizzani, S.C.3
-
139
-
-
2142640339
-
Gene therapies for osteoarthritis
-
Evans CH. Gene therapies for osteoarthritis. Curr Rheumatol Rep 2004; 6: 31-40.
-
(2004)
Curr Rheumatol Rep
, vol.6
, pp. 31-40
-
-
Evans, C.H.1
-
147
-
-
67749084439
-
Local delivery of a recombinant adeno-associated vector containing a tumour necrosis factor alpha antagonist gene in inflammatory arthritis: a phase 1 dose-escalation safety and tolerability study
-
Mease PJ, Hobbs K, Chalmers A, et al. Local delivery of a recombinant adeno-associated vector containing a tumour necrosis factor alpha antagonist gene in inflammatory arthritis: a phase 1 dose-escalation safety and tolerability study. Ann Rheum Dis 2009; 68: 1247-1254.
-
(2009)
Ann Rheum Dis
, vol.68
, pp. 1247-1254
-
-
Mease, P.J.1
Hobbs, K.2
Chalmers, A.3
-
148
-
-
77950657693
-
Safety, tolerability, and clinical outcomes after intraarticular injection of a recombinant adeno-associated vector containing a tumour necrosis factor antagonist gene: results of a phase 1/2 Study
-
Mease PJ, Wei N, Fudman EJ, et al. Safety, tolerability, and clinical outcomes after intraarticular injection of a recombinant adeno-associated vector containing a tumour necrosis factor antagonist gene: results of a phase 1/2 Study. J Rheumatol 2011; 37: 692-703.
-
(2011)
J Rheumatol
, vol.37
, pp. 692-703
-
-
Mease, P.J.1
Wei, N.2
Fudman, E.J.3
-
149
-
-
67650497832
-
Investigation of the cause of death in a gene-therapy trial
-
Frank KM, Hogarth DK, Miller JL, et al. Investigation of the cause of death in a gene-therapy trial. N Engl J Med 2009; 361: 161-169.
-
(2009)
N Engl J Med
, vol.361
, pp. 161-169
-
-
Frank, K.M.1
Hogarth, D.K.2
Miller, J.L.3
-
150
-
-
77956903435
-
The OARSI histopathology initiative - recommendations for histological assessments of osteoarthritis in the rat
-
Gerwin N, Bendele AM, Glasson S, et al. The OARSI histopathology initiative - recommendations for histological assessments of osteoarthritis in the rat. Osteoarthritis Cartilage 2010; 18(Suppl 3): S24-S34.
-
(2010)
Osteoarthritis Cartilage
, vol.18
, Issue.SUPPL 3
-
-
Gerwin, N.1
Bendele, A.M.2
Glasson, S.3
-
151
-
-
77956937521
-
The OARSI histopathology initiative - recommendations for histological assessments of osteoarthritis in the guinea pig
-
Kraus VB, Huebner JL, DeGroot J, et al. The OARSI histopathology initiative - recommendations for histological assessments of osteoarthritis in the guinea pig. Osteoarthritis Cartilage 2010; 18(Suppl 3): S35-S52.
-
(2010)
Osteoarthritis Cartilage
, vol.18
, Issue.SUPPL 3
-
-
Kraus, V.B.1
Huebner, J.L.2
DeGroot, J.3
-
152
-
-
77956924858
-
The OARSI histopathology initiative - recommendations for histological assessments of osteoarthritis in the mouse
-
Glasson SS, Chambers MG, van den Berg WB, et al. The OARSI histopathology initiative - recommendations for histological assessments of osteoarthritis in the mouse. Osteoarthritis Cartilage 2010; 18(Suppl 3): S17-S23.
-
(2010)
Osteoarthritis Cartilage
, vol.18
, Issue.SUPPL 3
-
-
Glasson, S.S.1
Chambers, M.G.2
van den Berg, W.B.3
-
153
-
-
77956908666
-
The OARSI histopathology initiative - recommendations for histological assessments of osteoarthritis in the rabbit
-
Laverty S, Girard CA, Williams JM, et al. The OARSI histopathology initiative - recommendations for histological assessments of osteoarthritis in the rabbit. Osteoarthritis Cartilage 2010; 18(Suppl 3): S53-S65.
-
(2010)
Osteoarthritis Cartilage
, vol.18
, Issue.SUPPL 3
-
-
Laverty, S.1
Girard, C.A.2
Williams, J.M.3
-
154
-
-
16544368753
-
Hindlimb loading, morphology and biochemistry of articular cartilage in the ACL-deficient cat knee
-
Herzog W, Adams ME, Matyas JR, et al. Hindlimb loading, morphology and biochemistry of articular cartilage in the ACL-deficient cat knee. Osteoarthritis Cartilage 1993; 1: 243-251.
-
(1993)
Osteoarthritis Cartilage
, vol.1
, pp. 243-251
-
-
Herzog, W.1
Adams, M.E.2
Matyas, J.R.3
-
155
-
-
77953699197
-
The OARSI histopathology initiative - recommendations for histological assessments of osteoarthritis in the dog
-
Cook JL, Kuroki K, Visco D, et al. The OARSI histopathology initiative - recommendations for histological assessments of osteoarthritis in the dog. Osteoarthritis Cartilage 2010; 18(Suppl 3): S66-S79.
-
(2010)
Osteoarthritis Cartilage
, vol.18
, Issue.SUPPL 3
-
-
Cook, J.L.1
Kuroki, K.2
Visco, D.3
-
156
-
-
14044279349
-
Long-term periarticular bone adaptation in a feline knee injury model for post-traumatic experimental osteoarthritis
-
Boyd SK, Muller R, Leonard T, et al. Long-term periarticular bone adaptation in a feline knee injury model for post-traumatic experimental osteoarthritis. Osteoarthritis Cartilage 2005; 13: 235-242.
-
(2005)
Osteoarthritis Cartilage
, vol.13
, pp. 235-242
-
-
Boyd, S.K.1
Muller, R.2
Leonard, T.3
-
157
-
-
84878111948
-
Examination of osteoarthritis and subchondral bone alterations within the stifle joint of an ovariectomised ovine model
-
Holland JC, Brennan O, Kennedy OD, et al. Examination of osteoarthritis and subchondral bone alterations within the stifle joint of an ovariectomised ovine model. J Anat 2013; 222: 588-597.
-
(2013)
J Anat
, vol.222
, pp. 588-597
-
-
Holland, J.C.1
Brennan, O.2
Kennedy, O.D.3
-
158
-
-
77956936940
-
Histopathology atlas of animal model systems - overview of guiding principles
-
Aigner T, Cook JL, Gerwin N, et al. Histopathology atlas of animal model systems - overview of guiding principles. Osteoarthritis Cartilage 2010; 18(Suppl 3): S2-S6.
-
(2010)
Osteoarthritis Cartilage
, vol.18
, Issue.SUPPL 3
-
-
Aigner, T.1
Cook, J.L.2
Gerwin, N.3
-
159
-
-
77956903436
-
Recommendations for the use of preclinical models in the study and treatment of osteoarthritis
-
Poole R, Blake S, Buschmann M, et al. Recommendations for the use of preclinical models in the study and treatment of osteoarthritis. Osteoarthritis Cartilage 2010; 18(Suppl 3): S10-S16.
-
(2010)
Osteoarthritis Cartilage
, vol.18
, Issue.SUPPL 3
-
-
Poole, R.1
Blake, S.2
Buschmann, M.3
|