Gene-mediated restoration of cartilage matrix by combination insulin-like growth factor-I/interleukin-1 receptor antagonist therapy

Gene Therapy

Volumn 12, Issue 2, 2005, Pages 177-186

  Nixon, A J ^a   Haupt, J L ^a   Frisbie, D D ^b   Morisset, S S ^b   McIlwraith, C W ^b   Robbins, P D ^c   Evans, C H ^d   Ghivizzani, S ^d  

^a Department of Obstetrics Gynecology   (United States)

^b Department of Environmental and Radiological Health Sciences   (United States)

^c UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^d HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Cartilage; Growth factor; IGF I; IL 1Ra; Repair

Indexed keywords

ADENOVIRUS VECTOR; COLLAGEN TYPE 2; COLLAGENASE 3; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; MESSENGER RNA; PROTEOGLYCAN; SOMATOMEDIN C;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BIOSYNTHESIS; CARTILAGE DEGENERATION; CARTILAGE MATRIX; CELL CULTURE; COCULTURE; CONTROLLED STUDY; CYTOMEGALOVIRUS; DISEASE ASSOCIATION; DRUG MECHANISM; EXPLANT; GENE EXPRESSION; HOMEOSTASIS; HORSE; IN VITRO STUDY; KNEE OSTEOARTHRITIS; MONOLAYER CULTURE; NONHUMAN; NORTHERN BLOTTING; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DEPLETION; PROTEIN EXPRESSION; SYNOVIOCYTE; SYNOVITIS; SYNOVIUM; TRANSGENE; VIRAL GENE DELIVERY SYSTEM;

ADENOVIRIDAE; ANIMALS; CARTILAGE; GENE EXPRESSION; GENE THERAPY; GENETIC VECTORS; HORSES; INSULIN-LIKE GROWTH FACTOR I; INTERLEUKIN 1 RECEPTOR ANTAGONIST PROTEIN; MODELS, ANIMAL; OSTEOARTHRITIS; SIALOGLYCOPROTEINS; SYNOVITIS; TISSUE CULTURE TECHNIQUES; TRANSDUCTION, GENETIC;

ADENOVIRIDAE; CUCUMBER MOSAIC VIRUS; CYTOMEGALOVIRUS;

EID: 13244269894     PISSN: 09697128     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.gt.3302396     Document Type: Article

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