Molecular mechanism of hypoxia-induced chondrogenesis and its application in in vivo cartilage tissue engineering

Biomaterials

Volumn 33, Issue 26, 2012, Pages 6042-6051

  Duval, Elise ^a   Baugé, Catherine ^a   Andriamanalijaona, Rina ^a   Bénateau, Hervé ^a,b   Leclercq, Sylvain ^a,c   Dutoit, Soizic ^a   Poulain, Laurent ^a   Galéra, Philippe ^a   Boumédiene, Karim ^a  

^a UNIVERSITÉ DE CAEN   (France)

^b CAEN UNIVERSITY HOSPITAL   (France)

^c Clinique Saint Martin   (France)

Author keywords

Cartilage repair; Chondrocytes; HIF 1; Hypoxia; Mesenchymal stem cells; Tissue engineering

Indexed keywords

CARTILAGE REPAIR; CHONDROCYTES; HIF-1; HYPOXIA; MESENCHYMAL STEM CELL;

BODY FLUIDS; CELL CULTURE; PEPTIDES; STEM CELLS; TISSUE; TISSUE ENGINEERING; TRANSCRIPTION FACTORS;

CARTILAGE;

COLLAGEN TYPE 10; COLLAGEN TYPE 2; HYPOXIA INDUCIBLE FACTOR 1ALPHA; TRANSCRIPTION FACTOR RUNX2; TRANSCRIPTION FACTOR SOX; TRANSCRIPTION FACTOR SOX5; TRANSCRIPTION FACTOR SOX6; TRANSCRIPTION FACTOR SOX9;

ADULT; AGED; ANIMAL EXPERIMENT; ARTICLE; CARTILAGE; CHONDROGENESIS; HISTOLOGY; HUMAN; HUMAN CELL; HYPOXIA; IN VIVO STUDY; LOSS OF FUNCTION MUTATION; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; TISSUE ENGINEERING;

AGED; ANIMALS; BLOTTING, WESTERN; CARTILAGE; CELL DIFFERENTIATION; CELL HYPOXIA; CELLS, CULTURED; CHONDROGENESIS; ELECTROPHORETIC MOBILITY SHIFT ASSAY; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; MESENCHYMAL STEM CELLS; MICE; MICE, NUDE; MIDDLE AGED; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TISSUE ENGINEERING;

MUS;

EID: 84862877054     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2012.04.061     Document Type: Article

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