The OARSI histopathology initiative - recommendations for histological assessments of osteoarthritis in the rat

Osteoarthritis and Cartilage

Volumn 18, Issue SUPPL. 3, 2010, Pages

  Gerwin, N ^a   Bendele, A M ^b   Glasson, S ^c   Carlson, C S ^d  

^a NOVARTIS PHARMA AG   (Switzerland)

^b UNIVERSITY OF COLORADO   (United States)

^c PFIZER INC   (United States)

^d UNIVERSITY OF MINNESOTA   (United States)

Author keywords

Cartilage; Chondrocyte; Degeneration; Score; Sectioning; Staining

Indexed keywords

ANTERIOR CRUCIATE LIGAMENT; ARTICLE; BONE LESION; CALCIFICATION; CARTILAGE DEGENERATION; DISEASE MODEL; HISTOPATHOLOGY; JOINT CAPSULE; KNEE LIGAMENT; KNEE MENISCUS; KNEE OSTEOARTHRITIS; MICROSCOPY; NONHUMAN; OSTEOPHYTE; PRIORITY JOURNAL; RAT; RELIABILITY; REPRODUCIBILITY; SCORING SYSTEM; STAINING; STANDARDIZATION; SYNOVIUM; TISSUE FIXATION; TISSUE SECTION;

ANIMALS; ARTHRITIS, EXPERIMENTAL; CARTILAGE, ARTICULAR; DISEASE MODELS, ANIMAL; HUMANS; JOINTS; OBSERVER VARIATION; OSTEOARTHRITIS; RATS; REPRODUCIBILITY OF RESULTS; SEVERITY OF ILLNESS INDEX; SYNOVIAL MEMBRANE;

EID: 77956903435     PISSN: 10634584     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.joca.2010.05.030     Document Type: Article

References (37)

1. Gyarmati J., Foldes I., Kern M., Kiss I. Morphological studies on the articular cartilage of old rats. Acta Morphol Hung 1987, 35(3-4):111-124.
2. Smale G., Bendele A., Horton W.R.J. Comparison of age-associated degeneration of articular cartilage in Wistar and Fischer 344 rats. Lab Anim Sci 1995, 45(2):191-194.
3. Bendele A.M. Animal models of osteoarthritis. J Musculoskelet Neuronal Interact 2001, 1(4):363-376.
4. Janusz M.J., Bendele A.M., Brown K.K., Taiwo Y.O., Hsieh L., Heitmeyer S.A. Induction of osteoarthritis in the rat by surgical tear of the meniscus: inhibition of joint damage by a matrix metalloproteinase inhibitor. Osteoarthritis and Cartilage 2002, 10(10):785-791.
5. Moore E.E., Bendele A.M., Thompson D.L., Littau A., Waggie K.S., Reardon B., et al. Fibroblast growth factor-18 stimulates chondrogenesis and cartilage repair in a rat model of injury-induced osteoarthritis. Osteoarthritis and Cartilage 2005, 13(7):623-631.
6. Williams J.M., Felten D.L., Peterson R.G., O'Connor B.L. Effects of surgically induced instability on rat knee articular cartilage. J Anat 1982, 134(Pt 1):103-109.
7. Stoop R., Buma P., van der Kraan P.M., Hollander A.P., Billinghurst R.C., Poole A.R., et al. Differences in type II collagen degradation between peripheral and central cartilage of rat stifle joints after cranial cruciate ligament transection. Arthritis Rheum 2000, 43(9):2121-2131.
8. Karahan S., Kincaid S.A., Kammermann J.R., Wright J.C. Evaluation of the rat stifle joint after transection of the cranial cruciate ligament and partial medial meniscectomy. Comp Med 2001, 51(6):504-512.
9. Hayami T., Pickarski M., Zhuo Y., Wesolowski G.A., Rodan G.A., Duong L.T. Characterization of articular cartilage and subchondral bone changes in the rat anterior cruciate ligament transection and meniscectomized models of osteoarthritis. Bone 2006, 38(2):234-243.
10. Appleton C.T., McErlain D.D., Pitelka V., Schwartz N., Bernier S.M., Henry J.L., et al. Forced mobilization accelerates pathogenesis: characterization of a pre-clinical surgical model of osteoarthritis. Arthritis Res Ther 2007, 9(1):R13.
11. Lozoya K.A., Flores J.B. A novel rat osteoarthrosis model to assess apoptosis and matrix degradation. Pathol Res Pract 2000, 196(11):729-745.
12. Galois L., Etienne S., Grossin L., Watrin-Pinzano A., Cournil-Henrionnet C., Loeuille D., et al. Dose-response relationship for exercise on severity of experimental osteoarthritis in rats: a pilot study. Osteoarthritis and Cartilage 2004, 12(10):779-786.
13. Kalbhen D.A. Chemical model of osteoarthritis-a pharmacological evaluation. J Rheumatol 1987, 14(Suppl 14). :130-131.
14. Guingamp C., Gegout-Pottie P., Philippe L., Terlain B., Netter P., Gillet P. Mono-iodoacetate-induced experimental osteoarthritis: a dose-response study of loss of mobility, morphology, and biochemistry. Arthritis Rheum 1997, 40(9):1670-1679.
15. Guzman R.E., Evans M.G., Bove S., Morenko B., Kilgore K. Mono-iodoacetate-induced histologic changes in subchondral bone and articular cartilage of rat femorotibial joints: an animal model of osteoarthritis. Toxicol Pathol 2003, 31(6):619-624.
16. Janusz M.J., Little C.B., King L.E., Hookfin E.B., Brown K.K., Heitmeyer S.A., et al. Detection of aggrecanase- and MMP-generated catabolic neoepitopes in the rat iodoacetate model of cartilage degeneration. Osteoarthritis and Cartilage 2004, 12(9):720-728.
17. Gelse K., von der Mark K., Aigner T., Park J., Schneider H. Articular cartilage repair by gene therapy using growth factor-producing mesenchymal cells. Arthritis Rheum 2003, 48(2):430-441.
18. Ikeda T., Kubo T., Nakanishi T., Arai Y., Kobayashi K., Mazda O., et al. Ex vivo gene delivery using an adenovirus vector in treatment for cartilage defects. J Rheumatol 2000, 27(4):990-996.
19. Kuroda R., Usas A., Kubo S., Corsi K., Peng H., Rose T., et al. Cartilage repair using bone morphogenetic protein 4 and muscle-derived stem cells. Arthritis Rheum 2006, 54(2):433-442.
20. Nishida T., Kubota S., Kojima S., Kuboki T., Nakao K., Kushibiki T., et al. Regeneration of defects in articular cartilage in rat knee joints by CCN2 (Connective Tissue Growth Factor). J Bone Miner Res 2004, 19(8):1308-1319.
21. Hoegh-Andersen P., Tanko L., Andersen T., Lundberg C., Mo J., Heegaard A.M., et al. Ovariectomized rats as a model of postmenopausal osteoarthritis: validation and application. Arthritis Res Ther 2004, 6(2):R169-R180.
22. Ekenstedt K.J., Sonntag W.E., Loeser R.F., Lindgren B.R., Carlson C.S. Effects of chronic growth hormone and insulin-like growth factor 1 deficiency on osteoarthritis severity in rat knee joints. Arthritis Rheum 2006, 54(12):3850-3858.
23. Baragi V.M., Becher G., Bendele A.M., Biesinger R., Bluhm H., Boer J., et al. A new class of potent matrix metalloproteinase 13 inhibitors for potential treatment of osteoarthritis: evidence of histologic and clinical efficacy without musculoskeletal toxicity in rat models. Arthritis Rheum 2009, 60(7):2008-2018.
24. Fernihough J., Gentry C., Malcangio M., Fox A., Rediske J., Pellas T., et al. Pain related behaviour in two models of osteoarthritis in the rat knee. Pain 2004, 112(1-2):83-93.
25. Bove S.E., Laemont K.D., Brooker R.M., Osborn M.N., Sanchez B.M., Guzman R.E., et al. Surgically induced osteoarthritis in the rat results in the development of both osteoarthritis-like joint pain and secondary hyperalgesia. Osteoarthritis and Cartilage 2006, 14(10):1041-1048.
26. Hayami T., Pickarski M., Wesolowski G.A., McLane J., Bone A., Destefano J., et al. The role of subchondral bone remodeling in osteoarthritis: reduction of cartilage degeneration and prevention of osteophyte formation by alendronate in the rat anterior cruciate ligament transection model. Arthritis Rheum 2004, 50(4):1193-1206.
27. Hyllested J.L., Veje K., Ostergaard K. Histochemical studies of the extracellular matrix of human articular cartilage-a review. Osteoarthritis and Cartilage 2002, 10(5):333-343.
28. Mankin H.J., Dorfman H.A., Lippiello L., Zarins A. Biochemical and metabolic abnormalities in articular cartilage from osteo-arthritic human hips: II. Correlation of morphology with biochemical and metabolic data. J Bone Joint Surg Am 1971, 53(3):523-537.
29. Flannery C., Zollner R., Corcoran C., Jones A., Root A., Rivera-Bermúdez M., et al. Prevention of cartilage degeneration in a rat model of osteoarthritis by intraarticular treatment with recombinant lubricin. Arthritis Rheum 2009, 60(3):840-847.
30. Yorimitsu M., Nishida K., Shimizu A., Doi H., Miyazawa S., Komiyama T., et al. Intra-articular injection of interleukin-4 decreases nitric oxide production by chondrocytes and ameliorates subsequent destruction of cartilage in instability-induced osteoarthritis in rat knee joints. Osteoarthritis and Cartilage 2008, 16(7):764-771.
31. Pritzker K.P.H., Gay S., Jimenez S.A., Ostergaard K., Pelletier J.P., Revell P.A., et al. Osteoarthritis cartilage histopathology: grading and staging. Osteoarthritis and Cartilage 2006, 14(1):13-29.
32. Wancket L.M., Baragi V., Bove S., Kilgore K., Korytko P.J., Guzman R.E. Anatomical localization of cartilage degradation markers in a surgically induced rat osteoarthritis Model. Toxicol Pathol 2005, 33(4):484-489.
33. Glasson S, Bendele AM, Sum P-E, Tam S, Tajeda J, Rivera-Bermúdez M, et al. Selective aggrecanase inhibition is disease modifying and pain alleviating in a rat meniscal tear model of osteoarthritis. Osteoarthritis and Cartilage 2009;17(Suppl.1); S56. Ref Type: Abstract.
34. Jean Y.H., Wen Z.H., Chang Y.C., Hsieh S.P., Tang C.C., Wang Y.H., et al. Intra-articular injection of the cyclooxygenase-2 inhibitor parecoxib attenuates osteoarthritis progression in anterior cruciate ligament-transected knee in rats: role of excitatory amino acids. Osteoarthritis and Cartilage 2007, 15(6):638-645.
35. Lin Y.S., Huang M.H., Chai C.Y. Effects of helium-neon laser on the mucopolysaccharide induction in experimental osteoarthritic cartilage. Osteoarthritis and Cartilage 2006, 14(4):377-383.
36. Yeh T., Wen Z., Lee H., Lee C., Yang Z., Jean Y., et al. Intra-articular injection of collagenase induced experimental osteoarthritis of the lumbar facet joint in rats. Eur Spine J 2008, 17(5):734-742.
37. Salo PT, Hogervorst T, Seerattan R, Rucker D, Bray RC Selective joint denervation promotes knee osteoarthritis in the aging rat. J Ortho Res 2002, 20(6):1256-1264.