-
1
-
-
77954215796
-
The infrapatellar fat pad should be considered as an active osteoarthritic joint tissue: a narrative review
-
Clockaerts S., Bastiaansen-Jenniskens Y.M., Runhaar J., van Osch G.J., van Offel J.F., Verhaar J.A., et al. The infrapatellar fat pad should be considered as an active osteoarthritic joint tissue: a narrative review. Osteoarthritis Cartilage 2010, 18:876-882.
-
(2010)
Osteoarthritis Cartilage
, vol.18
, pp. 876-882
-
-
Clockaerts, S.1
Bastiaansen-Jenniskens, Y.M.2
Runhaar, J.3
van Osch, G.J.4
van Offel, J.F.5
Verhaar, J.A.6
-
2
-
-
77953183739
-
Hypoxia inducible factor-2α is a catabolic regulator of osteoarthritic cartilage destruction
-
Yang S., Kim J., Ryu J.H., Oh H., Chun C.H., Kim B.J., et al. Hypoxia inducible factor-2α is a catabolic regulator of osteoarthritic cartilage destruction. Nat Med 2010, 16:687-694.
-
(2010)
Nat Med
, vol.16
, pp. 687-694
-
-
Yang, S.1
Kim, J.2
Ryu, J.H.3
Oh, H.4
Chun, C.H.5
Kim, B.J.6
-
3
-
-
77953208836
-
Transcriptional regulation of endochondral ossification by HIF-2α during skeletal growth and osteoarthritis development
-
Saito T., Fukai A., Mabuchi A., Ikeda T., Yano F., Ohba S., et al. Transcriptional regulation of endochondral ossification by HIF-2α during skeletal growth and osteoarthritis development. Nat Med 2010, 16:678-686.
-
(2010)
Nat Med
, vol.16
, pp. 678-686
-
-
Saito, T.1
Fukai, A.2
Mabuchi, A.3
Ikeda, T.4
Yano, F.5
Ohba, S.6
-
4
-
-
70349144133
-
Transcription factor NFAT1 deficiency causes osteoarthritis through dysfunction of adult articular chondrocytes
-
Wang J., Gardner B.M., Lu Q., Rodova M., Woodbury B.G., Yost J.G., et al. Transcription factor NFAT1 deficiency causes osteoarthritis through dysfunction of adult articular chondrocytes. J Pathol 2009, 219:163-172.
-
(2009)
J Pathol
, vol.219
, pp. 163-172
-
-
Wang, J.1
Gardner, B.M.2
Lu, Q.3
Rodova, M.4
Woodbury, B.G.5
Yost, J.G.6
-
5
-
-
77649128750
-
Autophagy is a protective mechanism in normal cartilage and its aging-related loss is linked with cell death and osteoarthritis
-
Carames B., Taniguchi N., Otsuki S., Blanco F.J., Lotz M. Autophagy is a protective mechanism in normal cartilage and its aging-related loss is linked with cell death and osteoarthritis. Arthritis Rheum 2010, 62:791-801.
-
(2010)
Arthritis Rheum
, vol.62
, pp. 791-801
-
-
Carames, B.1
Taniguchi, N.2
Otsuki, S.3
Blanco, F.J.4
Lotz, M.5
-
6
-
-
66049155861
-
Regulation of autophagy in human and murine cartilage: HIF2 suppresses chondrocyte autophagy
-
Bohensky J., Terkhorn S.P., Freeman T.A., Adams C.S., Garcia J.A., Shapiro I.M., et al. Regulation of autophagy in human and murine cartilage: HIF2 suppresses chondrocyte autophagy. Arthritis Rheum 2009, 60:1406-1415.
-
(2009)
Arthritis Rheum
, vol.60
, pp. 1406-1415
-
-
Bohensky, J.1
Terkhorn, S.P.2
Freeman, T.A.3
Adams, C.S.4
Garcia, J.A.5
Shapiro, I.M.6
-
7
-
-
0035165385
-
Postnatal expression in hyaline cartilage of constitutively active human collagenase-3 (MMP-13) induces osteoarthritis in mice
-
Neuhold L.A., Killar L., Zhao W., Sung M.L., Warner L., Kulik, et al. Postnatal expression in hyaline cartilage of constitutively active human collagenase-3 (MMP-13) induces osteoarthritis in mice. J Clin Invest 2001, 107:35-44.
-
(2001)
J Clin Invest
, vol.107
, pp. 35-44
-
-
Neuhold, L.A.1
Killar, L.2
Zhao, W.3
Sung, M.L.4
Warner, L.5
Kulik6
-
8
-
-
73249137617
-
Murine metalloproteinase 13-deficient mice are resistant to osteoarthritic cartilage erosion but not chondrocyte hypertrophy or osteophyte development
-
Little C.B., Barai A., Burkhardt D., Smith S.M., Fosang A.J., Werb Z., et al. Murine metalloproteinase 13-deficient mice are resistant to osteoarthritic cartilage erosion but not chondrocyte hypertrophy or osteophyte development. Arthritis Rheum 2009, 60:3723-3733.
-
(2009)
Arthritis Rheum
, vol.60
, pp. 3723-3733
-
-
Little, C.B.1
Barai, A.2
Burkhardt, D.3
Smith, S.M.4
Fosang, A.J.5
Werb, Z.6
-
9
-
-
15844413814
-
Deletion of ADAMTS5 prevents cartilage degradation in a murine model of osteoarthritis
-
Glasson S.S., Askew R., Sheppard B., Carito B., Blanchet T., Ma H.L., et al. Deletion of ADAMTS5 prevents cartilage degradation in a murine model of osteoarthritis. Nature 2005, 434:644-648.
-
(2005)
Nature
, vol.434
, pp. 644-648
-
-
Glasson, S.S.1
Askew, R.2
Sheppard, B.3
Carito, B.4
Blanchet, T.5
Ma, H.L.6
-
10
-
-
77956369628
-
Attenuation of osteoarthritis progression by reduction of discoidin domain receptor 2 in mice
-
Xu L., Servais J., Polur I., Kim D., Lee P.L., Chung K., et al. Attenuation of osteoarthritis progression by reduction of discoidin domain receptor 2 in mice. Arthritis Rheum 2010, 62:2736-2744.
-
(2010)
Arthritis Rheum
, vol.62
, pp. 2736-2744
-
-
Xu, L.1
Servais, J.2
Polur, I.3
Kim, D.4
Lee, P.L.5
Chung, K.6
-
11
-
-
69949118870
-
Syndecan-4 regulates ADAMTS-5 activation and cartilage breakdown in osteoarthritis
-
Echtermeyer F., Bertrand J., Dreier R., Meinecke I., Neugebauer K., Fuerst M., et al. Syndecan-4 regulates ADAMTS-5 activation and cartilage breakdown in osteoarthritis. Nat Med 2009, 15:1072-1077.
-
(2009)
Nat Med
, vol.15
, pp. 1072-1077
-
-
Echtermeyer, F.1
Bertrand, J.2
Dreier, R.3
Meinecke, I.4
Neugebauer, K.5
Fuerst, M.6
-
12
-
-
68049103239
-
Accelerated development of aging-associated and instability-induced osteoarthritis in osteopontin-deficient mice
-
Matsui Y., Iwasaki N., Kon S., Takahashi D., Morimoto J., Matsui Y., et al. Accelerated development of aging-associated and instability-induced osteoarthritis in osteopontin-deficient mice. Arthritis Rheum 2009, 60:2362-2371.
-
(2009)
Arthritis Rheum
, vol.60
, pp. 2362-2371
-
-
Matsui, Y.1
Iwasaki, N.2
Kon, S.3
Takahashi, D.4
Morimoto, J.5
Matsui, Y.6
-
13
-
-
38749144385
-
Syndecan-4 protects against osteopontin-mediated acute hepatic injury by masking functional domains of osteopontin
-
Kon S., Ikesue M., Kimura C., Aoki M., Nakayama Y., Saito Y., et al. Syndecan-4 protects against osteopontin-mediated acute hepatic injury by masking functional domains of osteopontin. J exp Med 2008, 205:25-33.
-
(2008)
J exp Med
, vol.205
, pp. 25-33
-
-
Kon, S.1
Ikesue, M.2
Kimura, C.3
Aoki, M.4
Nakayama, Y.5
Saito, Y.6
-
14
-
-
0033986279
-
OA-like changes in the murine knee joint resulting from intra-articular TGFβ injections
-
Van Beuningen H.M., Glansbeek H.L., van der Kraan P.M., van den Berg W.B. OA-like changes in the murine knee joint resulting from intra-articular TGFβ injections. Osteoarthritis Cartilage 2000, 8:25-33.
-
(2000)
Osteoarthritis Cartilage
, vol.8
, pp. 25-33
-
-
Van Beuningen, H.M.1
Glansbeek, H.L.2
van der Kraan, P.M.3
van den Berg, W.B.4
-
15
-
-
0036644328
-
Inhibition of endogenous TGFβ during experimental OA prevents osteophyte formation and impairs cartilage repair
-
Scharstuhl A., Glansbeek H.L., van Beuningen H.M., Vitters E.L., van der Kraan P.M., van den Berg W.B. Inhibition of endogenous TGFβ during experimental OA prevents osteophyte formation and impairs cartilage repair. J Immunol 2002, 169:507-514.
-
(2002)
J Immunol
, vol.169
, pp. 507-514
-
-
Scharstuhl, A.1
Glansbeek, H.L.2
van Beuningen, H.M.3
Vitters, E.L.4
van der Kraan, P.M.5
van den Berg, W.B.6
-
16
-
-
67649216115
-
Increase in ALK1/ALK5 ratio as a cause for elevated MMP-13 expression in osteoarthritis in humans and mice
-
Blaney Davidson E.N., Remst D.F., Vitters E.L., van Beuningen H.M., Blom A.B., Goumans M.J., et al. Increase in ALK1/ALK5 ratio as a cause for elevated MMP-13 expression in osteoarthritis in humans and mice. J Immunol 2009, 182:7937-7945.
-
(2009)
J Immunol
, vol.182
, pp. 7937-7945
-
-
Blaney Davidson, E.N.1
Remst, D.F.2
Vitters, E.L.3
van Beuningen, H.M.4
Blom, A.B.5
Goumans, M.J.6
-
17
-
-
77955411535
-
Aberrant hypertrophy in Smad3-deficient murine chondrocytes is rescued by restoring TGFβ-activated kinase 1/activating transcription factor 2 signaling: a potential clinical implication for osteoarthritis
-
Li T.F., Gao L., Sheu T.J., Sampson E.R., Flick L.M., Konttinen Y.T., et al. Aberrant hypertrophy in Smad3-deficient murine chondrocytes is rescued by restoring TGFβ-activated kinase 1/activating transcription factor 2 signaling: a potential clinical implication for osteoarthritis. Arthritis Rheum 2010, 62:2359-2369.
-
(2010)
Arthritis Rheum
, vol.62
, pp. 2359-2369
-
-
Li, T.F.1
Gao, L.2
Sheu, T.J.3
Sampson, E.R.4
Flick, L.M.5
Konttinen, Y.T.6
-
18
-
-
77955365705
-
Genetic variation in the SMAD3 gene is associated with hip and knee osteoarthritis
-
Valdes A.M., Spector T.D., Tamm A., Kisand K., Doherty S.A., Dennison E.M., et al. Genetic variation in the SMAD3 gene is associated with hip and knee osteoarthritis. Arthritis Rheum 2010, 62:2347-2352.
-
(2010)
Arthritis Rheum
, vol.62
, pp. 2347-2352
-
-
Valdes, A.M.1
Spector, T.D.2
Tamm, A.3
Kisand, K.4
Doherty, S.A.5
Dennison, E.M.6
-
19
-
-
34948900275
-
Mrp8 and Mrp14 are endogenous activators of TLR4, promoting lethal, endotoxin-induced shock
-
Vogl T., Tenbrock K., Ludwig S., Leukert N., Ehrhardt C., van Zoelen M.A., et al. Mrp8 and Mrp14 are endogenous activators of TLR4, promoting lethal, endotoxin-induced shock. Nat Med 2007, 13:1042-1049.
-
(2007)
Nat Med
, vol.13
, pp. 1042-1049
-
-
Vogl, T.1
Tenbrock, K.2
Ludwig, S.3
Leukert, N.4
Ehrhardt, C.5
van Zoelen, M.A.6
-
20
-
-
56749164528
-
Myeloid related proteins S100A8/S100A9 regulate joint inflammation and cartilage destruction during antigen induced arthritis
-
Van lent P.L., Grevers L., Blom A.B., Sloetjes A., Mort J.S., Volgl T., et al. Myeloid related proteins S100A8/S100A9 regulate joint inflammation and cartilage destruction during antigen induced arthritis. Ann Rheum Dis 2008, 67:1750-1758.
-
(2008)
Ann Rheum Dis
, vol.67
, pp. 1750-1758
-
-
Van lent, P.L.1
Grevers, L.2
Blom, A.B.3
Sloetjes, A.4
Mort, J.S.5
Volgl, T.6
-
21
-
-
57349090741
-
Simulation of chrondrocyte mediated cartilage destruction by S100A8 in experimental murine arthritis
-
Van Lent P.L., Grevers L.C., Blom A.B., Arntz O.J., van de Loo F.A., van der Kraan P.M., et al. Simulation of chrondrocyte mediated cartilage destruction by S100A8 in experimental murine arthritis. Arthritis Rheum 2008, 58:3776-3787.
-
(2008)
Arthritis Rheum
, vol.58
, pp. 3776-3787
-
-
Van Lent, P.L.1
Grevers, L.C.2
Blom, A.B.3
Arntz, O.J.4
van de Loo, F.A.5
van der Kraan, P.M.6
-
22
-
-
77649277920
-
S100A8 and S100A9 in experimental osteoarthritis
-
R16
-
Zreiqat H., Belluoccio D., Smith M.M., Wilson R., Rowley L.A., Jones K., et al. S100A8 and S100A9 in experimental osteoarthritis. Arthritis Res Ther 2010, 12. R16.
-
(2010)
Arthritis Res Ther
, vol.12
-
-
Zreiqat, H.1
Belluoccio, D.2
Smith, M.M.3
Wilson, R.4
Rowley, L.A.5
Jones, K.6
-
23
-
-
58149097603
-
Activation of β-catenin signaling in articular chondrocytes leads to OA-like phenotype in adult β-catenin conditional activation mice
-
Zhu M., Tang D., Wu Q., Hao S., Chen M., Xie C., et al. Activation of β-catenin signaling in articular chondrocytes leads to OA-like phenotype in adult β-catenin conditional activation mice. J Bone Min Res 2009, 24:12-21.
-
(2009)
J Bone Min Res
, vol.24
, pp. 12-21
-
-
Zhu, M.1
Tang, D.2
Wu, Q.3
Hao, S.4
Chen, M.5
Xie, C.6
-
24
-
-
77950664529
-
Beta-catenin, cartilage and osteoarthritis
-
Wu Q., Zhu M., Rosier R.N., Zuscik M.J., O'Keefe R.J., Chen D. Beta-catenin, cartilage and osteoarthritis. Ann N Y Acad Sci 2010, 1192:344-350.
-
(2010)
Ann N Y Acad Sci
, vol.1192
, pp. 344-350
-
-
Wu, Q.1
Zhu, M.2
Rosier, R.N.3
Zuscik, M.J.4
O'Keefe, R.J.5
Chen, D.6
-
25
-
-
77951073232
-
To seek shelter from the WNT in osteoarthritis? WNT-signaling as a target for osteoarthritis therapy
-
Blom A.B., van Lent P.L., van der Kraan P.M., van den Berg W.B. To seek shelter from the WNT in osteoarthritis? WNT-signaling as a target for osteoarthritis therapy. Curr Drug Targets 2010, 11:620-629.
-
(2010)
Curr Drug Targets
, vol.11
, pp. 620-629
-
-
Blom, A.B.1
van Lent, P.L.2
van der Kraan, P.M.3
van den Berg, W.B.4
|