-
1
-
-
0031856463
-
Articular cartilage repair and transplantation
-
Buckwalter, J.A., and Mankin, H.J. Articular cartilage repair and transplantation. Arthritis Rheum 41, 1331, 1998.
-
(1998)
Arthritis Rheum
, vol.41
, pp. 1331
-
-
Buckwalter, J.A.1
Mankin, H.J.2
-
2
-
-
0032425951
-
The healing and regeneration of articular cartilage
-
O'Driscoll, S.W. The healing and regeneration of articular cartilage. J Bone Joint Surg Am 80, 1795, 1998.
-
(1998)
J Bone Joint Surg Am
, vol.80
, pp. 1795
-
-
O'Driscoll, S.W.1
-
3
-
-
0031728565
-
Chondrogenic differentiation of cultured human mesenchymal stem cells from marrow
-
Mackay, A.M., Beck, S.C., Murphy, J.M., Barry, F.P., Chichester, C.O., and Pittenger, M.F. Chondrogenic differentiation of cultured human mesenchymal stem cells from marrow. Tissue Eng 4, 415, 1998.
-
(1998)
Tissue Eng
, vol.4
, pp. 415
-
-
MacKay, A.M.1
Beck, S.C.2
Murphy, J.M.3
Barry, F.P.4
Chichester, C.O.5
Pittenger, M.F.6
-
4
-
-
0032425950
-
The chondrogenic potential of human bone-marrow-derived mesenchymal progenitor cells
-
Yoo, J.U., Barther, T.S., Nishimura, K., Solchaga, L., Caplan, A.I., Goldberg, V.M., and Johnstone, B. The chondrogenic potential of human bone-marrow-derived mesenchymal progenitor cells. J Bone Joint Surg Am 80, 1745, 1998.
-
(1998)
J Bone Joint Surg Am
, vol.80
, pp. 1745
-
-
Yoo, J.U.1
Barther, T.S.2
Nishimura, K.3
Solchaga, L.4
Caplan, A.I.5
Goldberg, V.M.6
Johnstone, B.7
-
5
-
-
0033515827
-
Multilineage potential of adult human mesenchymal stem cells
-
Pittenger, M.F., Mackay, A.M., Beck, S.C., Jaiswal, R.K., Douglas, R., Mosca, J.D., Moorman, M.A., Simonetti, D.W., Craig, S., and Marshak, D.R. Multilineage potential of adult human mesenchymal stem cells. Science 284, 143, 1999.
-
(1999)
Science
, vol.284
, pp. 143
-
-
Pittenger, M.F.1
MacKay, A.M.2
Beck, S.C.3
Jaiswal, R.K.4
Douglas, R.5
Mosca, J.D.6
Moorman, M.A.7
Simonetti, D.W.8
Craig, S.9
Marshak, D.R.10
-
6
-
-
0035882056
-
Chondrogenic differentiation of mesenchymal stem cells from bone marrow: Differentiation-dependent gene expression of matrix components
-
Barry, F., Boynton, R.E., Liu, B., and Murphy, J.M. Chondrogenic differentiation of mesenchymal stem cells from bone marrow: differentiation- dependent gene expression of matrix components. Exp Cell Res 268, 189, 2001.
-
(2001)
Exp Cell Res
, vol.268
, pp. 189
-
-
Barry, F.1
Boynton, R.E.2
Liu, B.3
Murphy, J.M.4
-
7
-
-
0033775224
-
Using gene therapy to protect and restore cartilage
-
Evans, C.H., Ghivizzani, S.C., Smith, P., Shuler, F.D., Mi, Z., and Robbins, P.D. Using gene therapy to protect and restore cartilage. Clin Orthop Relat Res 379 Suppl, S214, 2000.
-
(2000)
Clin Orthop Relat Res
, vol.379
, Issue.SUPPL.
-
-
Evans, C.H.1
Ghivizzani, S.C.2
Smith, P.3
Shuler, F.D.4
Mi, Z.5
Robbins, P.D.6
-
8
-
-
0017355018
-
The progeny of rabbit articular chondrocytes synthesize collagen types i and III and type i trimer, but not type II. Verifications by cyanogen bromide peptide analysis
-
Benya, P.D., Padilla, S.R., and Nimni, M.E. The progeny of rabbit articular chondrocytes synthesize collagen types I and III and type I trimer, but not type II. Verifications by cyanogen bromide peptide analysis. Biochemistry 16, 865, 1977.
-
(1977)
Biochemistry
, vol.16
, pp. 865
-
-
Benya, P.D.1
Padilla, S.R.2
Nimni, M.E.3
-
9
-
-
0017723046
-
Relationship between cell shape and type of collagen synthesised as chondrocytes lose their cartilage phenotype in culture
-
von der Mark, K., Gauss, V., von der Mark, H., and Muller, P. Relationship between cell shape and type of collagen synthesised as chondrocytes lose their cartilage phenotype in culture. Nature 267, 531, 1977.
-
(1977)
Nature
, vol.267
, pp. 531
-
-
Von Der Mark, K.1
Gauss, V.2
Von Der Mark, H.3
Muller, P.4
-
10
-
-
33750289940
-
Stemming cartilage degeneration: Adult mesenchymal stem cells as a cell source for articular cartilage tissue engineering
-
Tuan, R.S. Stemming cartilage degeneration: adult mesenchymal stem cells as a cell source for articular cartilage tissue engineering. Arthritis Rheum 54, 3075, 2006.
-
(2006)
Arthritis Rheum
, vol.54
, pp. 3075
-
-
Tuan, R.S.1
-
11
-
-
34250196490
-
Major biological obstacles for persistent cell-based regeneration of articular cartilage
-
Steinert, A.F., Ghivizzani, S.C., Rethwilm, A., Tuan, R.S., Evans, C.H., and Nö th, U. Major biological obstacles for persistent cell-based regeneration of articular cartilage. Arthritis Res Ther 9, 213, 2007.
-
(2007)
Arthritis Res Ther
, vol.9
, pp. 213
-
-
Steinert, A.F.1
Ghivizzani, S.C.2
Rethwilm, A.3
Tuan, R.S.4
Evans, C.H.5
Nö Th, U.6
-
12
-
-
43949115205
-
Functional characterization of hypertrophy in chondrogenesis of human mesenchymal stem cells
-
Mueller, M.B., and Tuan, R.S. Functional characterization of hypertrophy in chondrogenesis of human mesenchymal stem cells. Arthritis Rheum 58, 1377, 2008.
-
(2008)
Arthritis Rheum
, vol.58
, pp. 1377
-
-
Mueller, M.B.1
Tuan, R.S.2
-
13
-
-
39749185584
-
The use ofmesenchymal stem cells for chondrogenesis
-
Pelttari, K., Steck, E., and Richter,W. The use ofmesenchymal stem cells for chondrogenesis. Injury 39 Suppl 1, S58, 2008.
-
(2008)
Injury
, vol.39
, Issue.SUPPL.1
-
-
Pelttari, K.1
Steck, E.2
Richter, W.3
-
14
-
-
29744465669
-
Gene therapy for cartilage defects
-
Cucchiarini, M., and Madry, H. Gene therapy for cartilage defects. J Gene Med 7, 1495, 2005.
-
(2005)
J Gene Med
, vol.7
, pp. 1495
-
-
Cucchiarini, M.1
Madry, H.2
-
15
-
-
0037297421
-
In vitro chondrogenesis of human bone marrow-derived mesenchymal progenitor cells in monolayer culture: Activation by transfection with TGF-beta2
-
Wang, W.G., Lou, S.Q., Ju, X.D., Xia, K., and Xia, J.H. In vitro chondrogenesis of human bone marrow-derived mesenchymal progenitor cells in monolayer culture: activation by transfection with TGF-beta2. Tissue Cell 35, 69, 2003.
-
(2003)
Tissue Cell
, vol.35
, pp. 69
-
-
Wang, W.G.1
Lou, S.Q.2
Ju, X.D.3
Xia, K.4
Xia, J.H.5
-
16
-
-
22144463885
-
Adenoviral-mediated transfer of TGF-beta1 but not IGF-1 induces chondrogenic differentiation of human mesenchymal stem cells in pellet cultures
-
Kawamura, K., Chu, C.R., Sobajima, S., Robbins, P.D., Fu, F.H., Izzo, N.J., and Niyibizi, C. Adenoviral-mediated transfer of TGF-beta1 but not IGF-1 induces chondrogenic differentiation of human mesenchymal stem cells in pellet cultures. Exp Hematol 33, 865, 2005.
-
(2005)
Exp Hematol
, vol.33
, pp. 865
-
-
Kawamura, K.1
Chu, C.R.2
Sobajima, S.3
Robbins, P.D.4
Fu, F.H.5
Izzo, N.J.6
Niyibizi, C.7
-
17
-
-
22644444720
-
Gene-induced chondrogenesis of primary mesenchymal stem cells in vitro
-
Palmer, G.D., Steinert, A., Pascher, A., Gouze, E., Gouze, J.N., Betz, O., Johnsotne, B., Evans, C.H., and Ghivizzani, S.C. Gene-induced chondrogenesis of primary mesenchymal stem cells in vitro. Mol Ther 12, 219, 2005.
-
(2005)
Mol Ther
, vol.12
, pp. 219
-
-
Palmer, G.D.1
Steinert, A.2
Pascher, A.3
Gouze, E.4
Gouze, J.N.5
Betz, O.6
Johnsotne, B.7
Evans, C.H.8
Ghivizzani, S.C.9
-
18
-
-
34248181957
-
Adeno-associated viral gene transfer of transforming growth factor-beta1 to human mesenchymal stem cells improves cartilage repair
-
Pagnotto, M.R., Wang, Z., Karpie, J.C., Ferretti, M., Xiao, X., and Chu, C.R. Adeno-associated viral gene transfer of transforming growth factor-beta1 to human mesenchymal stem cells improves cartilage repair. Gene Ther 14, 804, 2007.
-
(2007)
Gene Ther
, vol.14
, pp. 804
-
-
Pagnotto, M.R.1
Wang, Z.2
Karpie, J.C.3
Ferretti, M.4
Xiao, X.5
Chu, C.R.6
-
19
-
-
66249107073
-
Enhanced in vitro chondrogenesis of primary mesenchymal stem cells by combined gene transfer
-
Steinert, A.F., Palmer, G.D., Pilipil, C., Nö th, U., Evans, C.H., and Ghivizzani, S.C. Enhanced in vitro chondrogenesis of primary mesenchymal stem cells by combined gene transfer. Tissue Eng Part A 15, 1127, 2009.
-
(2009)
Tissue Eng Part A
, vol.15
, pp. 1127
-
-
Steinert, A.F.1
Palmer, G.D.2
Pilipil, C.3
Nö Th, U.4
Evans, C.H.5
Ghivizzani, S.C.6
-
20
-
-
31644434203
-
Transgene-activated mesenchymal cells for articular cartilage repair: A comparison of primary bone marrow-, perichondrium/periosteum-and fat-derived cells
-
Park, J., Gelse, K., Frank, S., von der Mark, K., Aigner, T., and Schneider, H. Transgene-activated mesenchymal cells for articular cartilage repair: a comparison of primary bone marrow-, perichondrium/periosteum-and fat-derived cells. J Gene Med 8, 112, 2006.
-
(2006)
J Gene Med
, vol.8
, pp. 112
-
-
Park, J.1
Gelse, K.2
Frank, S.3
Von Der Mark, K.4
Aigner, T.5
Schneider, H.6
-
21
-
-
75749116750
-
Impact of growth factors and PTHrP on early and late chondrogenic differentiation of human mesenchymal stem cells
-
Weiss, S., Hennig, T., Bock, R., Steck, E., and Richter, W. Impact of growth factors and PTHrP on early and late chondrogenic differentiation of human mesenchymal stem cells. J Cell Physiol 223, 84, 2010.
-
(2010)
J Cell Physiol
, vol.223
, pp. 84
-
-
Weiss, S.1
Hennig, T.2
Bock, R.3
Steck, E.4
Richter, W.5
-
22
-
-
33645337383
-
Effect of IGF-I in the chondrogenesis of bone marrow mesenchymal stem cells in the presence or absence of TGF-beta signaling
-
Longobardi, L., O'Rear, L., Aakula, S., Johnstone, B., Shimer, K., Chytil, A., Horton, W.A., Moses, H.L., and Spagnoli, A. Effect of IGF-I in the chondrogenesis of bone marrow mesenchymal stem cells in the presence or absence of TGF-beta signaling. J Bone Miner Res 21, 626, 2006.
-
(2006)
J Bone Miner Res
, vol.21
, pp. 626
-
-
Longobardi, L.1
O'Rear, L.2
Aakula, S.3
Johnstone, B.4
Shimer, K.5
Chytil, A.6
Horton, W.A.7
Moses, H.L.8
Spagnoli, A.9
-
23
-
-
0035955303
-
Retention of multilineage differentiation potential of mesenchymal cells during proliferation in response to FGF
-
Tsutsumi, S., Shimazu, A., Miyazaki, K., Pan, H., Koike, C., Yoshida, E., Takagishi, K., and Kato, Y. Retention of multilineage differentiation potential of mesenchymal cells during proliferation in response to FGF. Biochem Biophys Res Commun 288, 413, 2001.
-
(2001)
Biochem Biophys Res Commun
, vol.288
, pp. 413
-
-
Tsutsumi, S.1
Shimazu, A.2
Miyazaki, K.3
Pan, H.4
Koike, C.5
Yoshida, E.6
Takagishi, K.7
Kato, Y.8
-
24
-
-
18144391965
-
FGF signaling in the developing endochondral skeleton
-
Ornitz, D.M. FGF signaling in the developing endochondral skeleton. Cytokine Growth Factor Rev 16, 205, 2005.
-
(2005)
Cytokine Growth Factor Rev
, vol.16
, pp. 205
-
-
Ornitz, D.M.1
-
25
-
-
16344377055
-
FGF-2 enhances the mitotic and chondrogenic potentials of human adult bone marrow-derived mesenchymal stem cells
-
Solchaga, L.A., Penick, K., Goldberg, V.M., Caplan, A.I., and Welter, J.F. FGF-2 enhances the mitotic and chondrogenic potentials of human adult bone marrow-derived mesenchymal stem cells. J Cell Physiol 203, 398, 2005.
-
(2005)
J Cell Physiol
, vol.203
, pp. 398
-
-
Solchaga, L.A.1
Penick, K.2
Goldberg, V.M.3
Caplan, A.I.4
Welter, J.F.5
-
26
-
-
77649243276
-
Fibroblast growth factor-2 enhances proliferation and delays loss of chondrogenic potential in human adult bone-marrow-derived mesenchymal stem cells
-
Solchaga, L.A., Penick, K., Goldberg, V.M., Caplan, A.I., and Welter, J.F. Fibroblast growth factor-2 enhances proliferation and delays loss of chondrogenic potential in human adult bone-marrow-derived mesenchymal stem cells. Tissue Eng Part A 16, 1009, 2010.
-
(2010)
Tissue Eng Part A
, vol.16
, pp. 1009
-
-
Solchaga, L.A.1
Penick, K.2
Goldberg, V.M.3
Caplan, A.I.4
Welter, J.F.5
-
27
-
-
0037423736
-
Chondrogenesis enhanced by overexpression of sox9 gene in mouse bone marrow-derived mesenchymal stem cells
-
Tsuchiya, H., Kitoh, H., Sugiura, F., and Ishiguro, N. Chondrogenesis enhanced by overexpression of sox9 gene in mouse bone marrow-derived mesenchymal stem cells. Biochem Biophys Res Commun 301, 338, 2003.
-
(2003)
Biochem Biophys Res Commun
, vol.301
, pp. 338
-
-
Tsuchiya, H.1
Kitoh, H.2
Sugiura, F.3
Ishiguro, N.4
-
28
-
-
8444233948
-
The combination of SOX5, SOX6, and SOX9 (the SOX trio) provides signals sufficient for induction of permanent cartilage
-
Ikeda, T., Kamekura, S., Mabuchi, A., Seki, S., Takato, T., Nakamura, K., Kawaguchi, H., Ikegawa, S., and Chung, U.I. The combination of SOX5, SOX6, and SOX9 (the SOX trio) provides signals sufficient for induction of permanent cartilage. Arthritis Rheum 50, 3561, 2004.
-
(2004)
Arthritis Rheum
, vol.50
, pp. 3561
-
-
Ikeda, T.1
Kamekura, S.2
Mabuchi, A.3
Seki, S.4
Takato, T.5
Nakamura, K.6
Kawaguchi, H.7
Ikegawa, S.8
Chung, U.I.9
-
29
-
-
35348942941
-
Genetic manipulation of human mesenchymal progenitors to promote chondrogenesis using "beadin-bead" polysaccharide capsules
-
Babister, J.C., Tare, R.S., Green, D.W., Inglis, S., Mann, S., and Oreffo, R.O. Genetic manipulation of human mesenchymal progenitors to promote chondrogenesis using "beadin-bead" polysaccharide capsules. Biomaterials 29, 58, 2008.
-
(2008)
Biomaterials
, vol.29
, pp. 58
-
-
Babister, J.C.1
Tare, R.S.2
Green, D.W.3
Inglis, S.4
Mann, S.5
Oreffo, R.O.6
-
30
-
-
77953351772
-
Improving chondrogenesis: Potential and limitations of SOX9 gene transfer and mechanical stimulation for cartilage tissue engineering
-
Kupcsik, L., Stoddart, M.J., Li, Z., Benneker, L.M., and Alini, M. Improving chondrogenesis: potential and limitations of SOX9 gene transfer and mechanical stimulation for cartilage tissue engineering. Tissue Eng Part A 16, 1845, 2010.
-
(2010)
Tissue Eng Part A
, vol.16
, pp. 1845
-
-
Kupcsik, L.1
Stoddart, M.J.2
Li, Z.3
Benneker, L.M.4
Alini, M.5
-
31
-
-
0035984714
-
Telomerase expression extends the proliferative life-span and maintains the osteogenic potential of human bone marrow stromal cells
-
Simonsen, J.L., Rosada, C., Serakinci, N., Justesen, J., Stenderup, K., Rattan, S.I., Jensen, T.G., and Kassem, M. Telomerase expression extends the proliferative life-span and maintains the osteogenic potential of human bone marrow stromal cells. Nat Biotechnol 20, 592, 2002.
-
(2002)
Nat Biotechnol
, vol.20
, pp. 592
-
-
Simonsen, J.L.1
Rosada, C.2
Serakinci, N.3
Justesen, J.4
Stenderup, K.5
Rattan, S.I.6
Jensen, T.G.7
Kassem, M.8
-
32
-
-
77649217768
-
Enhanced treatment of articular cartilage defect of the knee by intra-articular injection of Bcl-xL-engineered mesenchymal stem cells in rabbit model
-
Hu, B., Ren, J.L., Zhang, J.R., Ma, Q., Liu, Y.P., and Mao, T.Q. Enhanced treatment of articular cartilage defect of the knee by intra-articular injection of Bcl-xL-engineered mesenchymal stem cells in rabbit model. J Tissue Eng Regen Med 4, 105, 2010.
-
(2010)
J Tissue Eng Regen Med
, vol.4
, pp. 105
-
-
Hu, B.1
Ren, J.L.2
Zhang, J.R.3
Ma, Q.4
Liu, Y.P.5
Mao, T.Q.6
-
33
-
-
10744222737
-
Gene targeting in stem cells from individuals with osteogenesis imperfecta
-
Chamberlain, J.R., Schwarze, U., Wang, P.R., Hirata, R.K., Hankeson, K.D., Pace, J.M., Underwood, R.A., Song, K.M., Sussman, M., Byers, P.H., and Russell, D.W. Gene targeting in stem cells from individuals with osteogenesis imperfecta. Science 303, 1198, 2004.
-
(2004)
Science
, vol.303
, pp. 1198
-
-
Chamberlain, J.R.1
Schwarze, U.2
Wang, P.R.3
Hirata, R.K.4
Hankeson, K.D.5
Pace, J.M.6
Underwood, R.A.7
Song, K.M.8
Sussman, M.9
Byers, P.H.10
Russell, D.W.11
-
34
-
-
34249987137
-
Adeno-associated viral vector transduction of human mesenchymal stem cells
-
Stender, S., Murphy, M., O'Brien, T., Stengaard, C., Ulrich-Vinther, M., Soballe, K., and Barry, F. Adeno-associated viral vector transduction of human mesenchymal stem cells. Eur Cell Mater 13, 93, 2007.
-
(2007)
Eur Cell Mater
, vol.13
, pp. 93
-
-
Stender, S.1
Murphy, M.2
O'Brien, T.3
Stengaard, C.4
Ulrich-Vinther, M.5
Soballe, K.6
Barry, F.7
-
35
-
-
0001592496
-
Adenovirus-associated defective virus particles
-
Atchison, R.W., Casto, B.C., and Hammon, W.M. Adenovirus-associated defective virus particles. Science 149, 754, 1965.
-
(1965)
Science
, vol.149
, pp. 754
-
-
Atchison, R.W.1
Casto, B.C.2
Hammon, W.M.3
-
36
-
-
0034241592
-
Adeno-associated virus mediates longterm gene transfer and delivery of chondroprotective IL-4 to murine synovium
-
Watanabe, S., Imagawa, T., Boivin, G.P., Gao, G., Wilson, J.M., and Hirsch, R. Adeno-associated virus mediates longterm gene transfer and delivery of chondroprotective IL-4 to murine synovium. Mol Ther 2, 147, 2000.
-
(2000)
Mol Ther
, vol.2
, pp. 147
-
-
Watanabe, S.1
Imagawa, T.2
Boivin, G.P.3
Gao, G.4
Wilson, J.M.5
Hirsch, R.6
-
37
-
-
22644436809
-
Improved tissue repair in articular cartilage defects in vivo by rAAV-mediated overexpression of human fibroblast growth factor 2
-
Cucchiarini, M., Madry, H., Ma, C., Thurn, T., Zurakowski, D., Menger, M.D., Kohn, D., Trippel, S.B., and Terwilliger, E.F. Improved tissue repair in articular cartilage defects in vivo by rAAV-mediated overexpression of human fibroblast growth factor 2. Mol Ther 12, 229, 2005.
-
(2005)
Mol Ther
, vol.12
, pp. 229
-
-
Cucchiarini, M.1
Madry, H.2
Ma, C.3
Thurn, T.4
Zurakowski, D.5
Menger, M.D.6
Kohn, D.7
Trippel, S.B.8
Terwilliger, E.F.9
-
38
-
-
29244437207
-
Repair of articular cartilage defect by intraarticular administration of basic fibroblast growth factor gene, using adeno-associated virus vector
-
Hiraide, A., Yokoo, N., Xin, K.Q., Okuda, K., Mizukami, H., Ozawa, K., and Saito, T. Repair of articular cartilage defect by intraarticular administration of basic fibroblast growth factor gene, using adeno-associated virus vector. Hum Gene Ther 16, 1413, 2005.
-
(2005)
Hum Gene Ther
, vol.16
, pp. 1413
-
-
Hiraide, A.1
Yokoo, N.2
Xin, K.Q.3
Okuda, K.4
Mizukami, H.5
Ozawa, K.6
Saito, T.7
-
39
-
-
20144387650
-
Remodeling of cortical bone allografts mediated by adherent rAAV-RANKL and VEGF gene therapy
-
Ito, H., Koefed, M., Tiyapatanaputi, P., Gromov, K., Goater, J.J., Carmouche, J., Zhang, X., Rubery, P.T., Rabinowitz, J., Samulski, R.J., Nakamura, T., Soballe, K., O'Keefe, R.J., Boyce, B.F., and Schwartz, E.M. Remodeling of cortical bone allografts mediated by adherent rAAV-RANKL and VEGF gene therapy. Nat Med 11, 291, 2005.
-
(2005)
Nat Med
, vol.11
, pp. 291
-
-
Ito, H.1
Koefed, M.2
Tiyapatanaputi, P.3
Gromov, K.4
Goater, J.J.5
Carmouche, J.6
Zhang, X.7
Rubery, P.T.8
Rabinowitz, J.9
Samulski, R.J.10
Nakamura, T.11
Soballe, K.12
O'Keefe, R.J.13
Boyce, B.F.14
Schwartz, E.M.15
-
40
-
-
68949205604
-
Intraarticular gene delivery and expression of interleukin-1Ra mediated by self-complementary adeno-associated virus
-
Kay, J.D., Gouze, E., Oligino, J., Gouze, J.N., Watson, R.S., Levings, P.P., Bush, M.L., Dacanay, A., Nickerson, D.M., Robbins, P.D., Evans, C.H., and Ghivizzani, S.C. Intraarticular gene delivery and expression of interleukin-1Ra mediated by self-complementary adeno-associated virus. J Gene Med 11, 605, 2009.
-
(2009)
J Gene Med
, vol.11
, pp. 605
-
-
Kay, J.D.1
Gouze, E.2
Oligino, J.3
Gouze, J.N.4
Watson, R.S.5
Levings, P.P.6
Bush, M.L.7
Dacanay, A.8
Nickerson, D.M.9
Robbins, P.D.10
Evans, C.H.11
Ghivizzani, S.C.12
-
41
-
-
77649121784
-
Adeno-associated virus type 5-mediated intraarticular administration of tumor necrosis factor small interfering RNA improves collagen-induced arthritis
-
Khoury, M., Courties, G., Fabre, S., Bouffi, C., Seemayer, C.A., Vervoordeldonk, M.J., Tak, P.P., Jorgensen, C., and Apparailly, F. Adeno-associated virus type 5-mediated intraarticular administration of tumor necrosis factor small interfering RNA improves collagen-induced arthritis. Arthritis Rheum 62, 765, 2010.
-
(2010)
Arthritis Rheum
, vol.62
, pp. 765
-
-
Khoury, M.1
Courties, G.2
Fabre, S.3
Bouffi, C.4
Seemayer, C.A.5
Vervoordeldonk, M.J.6
Tak, P.P.7
Jorgensen, C.8
Apparailly, F.9
-
42
-
-
77950657693
-
Safety, tolerability, and clinical outcomes after intraarticular injection of a recombinant adeno-associated vector containing a tumor necrosis factor antagonist gene: Results of a phase 1/2 study
-
Mease, P.J., Wei, N., Fudman, E.J., Kivitz, A.J., Schechtman, J., Trapp, R.G., Hobbs, K.F., Greenwald, M., Hou, A., Bookbinder, S.A., Grahma, G.E., Wiesenhutter, C.W., Willis, L., Ruderman, E.M., Forstot, J.Z., Maricic, M.J., Dao, K.H., Pritchard, C.H., Fiske, D.N., Burch, F.X., Prupas, H.M., Anklesaria, P., and Heald A.E. Safety, tolerability, and clinical outcomes after intraarticular injection of a recombinant adeno-associated vector containing a tumor necrosis factor antagonist gene: results of a phase 1/2 study. J Rheumatol 37, 692, 2010.
-
(2010)
J Rheumatol
, vol.37
, pp. 692
-
-
Mease, P.J.1
Wei, N.2
Fudman, E.J.3
Kivitz, A.J.4
Schechtman, J.5
Trapp, R.G.6
Hobbs, K.F.7
Greenwald, M.8
Hou, A.9
Bookbinder, S.A.10
Grahma, G.E.11
Wiesenhutter, C.W.12
Willis, L.13
Ruderman, E.M.14
Forstot, J.Z.15
Maricic, M.J.16
Dao, K.H.17
Pritchard, C.H.18
Fiske, D.N.19
Burch, F.X.20
Prupas, H.M.21
Anklesaria, P.22
Heald, A.E.23
more..
-
43
-
-
0025253540
-
Fibroblast growth factor is an inhibitor of chondrocyte terminal differentiation
-
Kato, Y., and Iwamoto, M. Fibroblast growth factor is an inhibitor of chondrocyte terminal differentiation. J Biol Chem 265, 5903, 1990.
-
(1990)
J Biol Chem
, vol.265
, pp. 5903
-
-
Kato, Y.1
Iwamoto, M.2
-
44
-
-
0028918872
-
Regulation of proliferation and osteochondrogenic differentiation of periosteum-derived cells by transforming growth factor-beta and basic fibroblast growth factor
-
Iwasaki, M., Nakahara, H., Nakata, K., Nakase, T., Kimura, T., and Ono, K. Regulation of proliferation and osteochondrogenic differentiation of periosteum-derived cells by transforming growth factor-beta and basic fibroblast growth factor. J Bone Joint Surg Am 77, 543, 1995.
-
(1995)
J Bone Joint Surg Am
, vol.77
, pp. 543
-
-
Iwasaki, M.1
Nakahara, H.2
Nakata, K.3
Nakase, T.4
Kimura, T.5
Ono, K.6
-
45
-
-
0028914213
-
In vitro effects of growth factors and dexamethasone on rat marrow stromal cells
-
Locklin, R.M., Williamson, M.C., Beresford, J.N., Triffitt, J.T., and Owen, M.E. In vitro effects of growth factors and dexamethasone on rat marrow stromal cells. Clin Orthop Relat Res 313, 27, 1995.
-
(1995)
Clin Orthop Relat Res
, vol.313
, pp. 27
-
-
Locklin, R.M.1
Williamson, M.C.2
Beresford, J.N.3
Triffitt, J.T.4
Owen, M.E.5
-
46
-
-
0033084169
-
Effects of TGFbeta and bFGF on the differentiation of human bone marrow stromal fibroblasts
-
Locklin, R.M., Oreffo, R.O., and Triffitt, J.T. Effects of TGFbeta and bFGF on the differentiation of human bone marrow stromal fibroblasts. Cell Biol Int 23, 185, 1999.
-
(1999)
Cell Biol Int
, vol.23
, pp. 185
-
-
Locklin, R.M.1
Oreffo, R.O.2
Triffitt, J.T.3
-
47
-
-
0025017687
-
Rapid onset synovial inflammation and hyperplasia induced by transforming growth factor beta
-
Allen, J.B., Manthey, C.L., Hand, A.R., Ohura, K., Ellingsworth, L., and Wahl, S.M. Rapid onset synovial inflammation and hyperplasia induced by transforming growth factor beta. J Exp Med 171, 231, 1990.
-
(1990)
J Exp Med
, vol.171
, pp. 231
-
-
Allen, J.B.1
Manthey, C.L.2
Hand, A.R.3
Ohura, K.4
Ellingsworth, L.5
Wahl, S.M.6
-
48
-
-
0028169834
-
Transforming growth factor-beta 1 stimulates articular chondrocyte proteoglycan synthesis and induces osteophyte formation in the murine knee joint
-
van Beuningen, H.M., van der Kraan, P.M., Arntz, O.J., and van den Berg, W.B. Transforming growth factor-beta 1 stimulates articular chondrocyte proteoglycan synthesis and induces osteophyte formation in the murine knee joint. Lab Invest 71, 279, 1994.
-
(1994)
Lab Invest
, vol.71
, pp. 279
-
-
Van Beuningen, H.M.1
Van Der Kraan, P.M.2
Arntz, O.J.3
Van Den Berg, W.B.4
-
49
-
-
0034790822
-
Chondrogenesis in cartilage repair is induced by members of the transforming growth factor-beta superfamily
-
Hunziker, E.B., Driesang, I.M., and Morris, E.A. Chondrogenesis in cartilage repair is induced by members of the transforming growth factor-beta superfamily. Clin Orthop Relat Res 391 Suppl, S171, 2001.
-
(2001)
Clin Orthop Relat Res
, vol.391
, Issue.SUPPL.
-
-
Hunziker, E.B.1
Driesang, I.M.2
Morris, E.A.3
-
50
-
-
0042622575
-
Adverse effects of adenovirusmediated gene transfer of human transforming growth factor beta 1 into rabbit knees
-
Mi, Z., Ghivizzani, S.C., Lechman, E., Glorioso, J.C., Evans, C.H., and Robbins, P.D. Adverse effects of adenovirusmediated gene transfer of human transforming growth factor beta 1 into rabbit knees. Arthritis Res Ther 5, R132, 2003.
-
(2003)
Arthritis Res Ther
, vol.5
-
-
Mi, Z.1
Ghivizzani, S.C.2
Lechman, E.3
Glorioso, J.C.4
Evans, C.H.5
Robbins, P.D.6
-
51
-
-
0023216839
-
A recombinant plasmid from which an infectious adeno-associated virus genome can be excised in vitro and its use to study viral replication
-
Samulski, R.J., Chang, L.S., and Shenk, T. A recombinant plasmid from which an infectious adeno-associated virus genome can be excised in vitro and its use to study viral replication. J Virol 61, 3096, 1987.
-
(1987)
J Virol
, vol.61
, pp. 3096
-
-
Samulski, R.J.1
Chang, L.S.2
Shenk, T.3
-
52
-
-
0024311525
-
Helper-free stocks of recombinant adeno-associated viruses: Normal integration does not require viral gene expression
-
Samulski, R.J., Chang, L.S., and Shenk, T. Helper-free stocks of recombinant adeno-associated viruses: normal integration does not require viral gene expression. J Virol 63, 3822, 1989.
-
(1989)
J Virol
, vol.63
, pp. 3822
-
-
Samulski, R.J.1
Chang, L.S.2
Shenk, T.3
-
53
-
-
0012296395
-
Selective gene expression in brain microglia mediated via adeno-associated virus type 2 and type 5 vectors
-
Cucchiarini, M., Ren, X.L., Perides, G., and Terwilliger, E.F. Selective gene expression in brain microglia mediated via adeno-associated virus type 2 and type 5 vectors. Gene Ther 10, 657, 2003.
-
(2003)
Gene Ther
, vol.10
, pp. 657
-
-
Cucchiarini, M.1
Ren, X.L.2
Perides, G.3
Terwilliger, E.F.4
-
54
-
-
0037338160
-
Recombinant adeno-associated virus vectors efficiently and persistently transduce chondrocytes in normal and osteoarthritic human articular cartilage
-
Madry, H., Cucchiarini, M., Terwilliger, E.F., and Trippel, S.B. Recombinant adeno-associated virus vectors efficiently and persistently transduce chondrocytes in normal and osteoarthritic human articular cartilage. Hum Gene Ther 14, 393, 2003.
-
(2003)
Hum Gene Ther
, vol.14
, pp. 393
-
-
Madry, H.1
Cucchiarini, M.2
Terwilliger, E.F.3
Trippel, S.B.4
-
55
-
-
33846208305
-
Restoration of the extracellular matrix in human osteoarthritic articular cartilage by overexpression of the transcription factor SOX9
-
Cucchiarini, M., Thurn, T., Weimer, A., Kohn, D., Terwilliger, E.F., and Madry, H. Restoration of the extracellular matrix in human osteoarthritic articular cartilage by overexpression of the transcription factor SOX9. Arthritis Rheum 56, 158, 2007.
-
(2007)
Arthritis Rheum
, vol.56
, pp. 158
-
-
Cucchiarini, M.1
Thurn, T.2
Weimer, A.3
Kohn, D.4
Terwilliger, E.F.5
Madry, H.6
-
56
-
-
72949105817
-
Remodelling of human osteoarthritic cartilage by FGF-2, alone or combined with Sox9 via rAAV gene transfer
-
Cucchiarini, M., Terwilliger, E.F., Kohn, D., and Madry, H. Remodelling of human osteoarthritic cartilage by FGF-2, alone or combined with Sox9 via rAAV gene transfer. J Cell Mol Med 13, 2476, 2009.
-
(2009)
J Cell Mol Med
, vol.13
, pp. 2476
-
-
Cucchiarini, M.1
Terwilliger, E.F.2
Kohn, D.3
Madry, H.4
-
57
-
-
70449720789
-
RAAV-mediated overexpression of FGF-2 promotes cell proliferation, survival, and alpha-SMA expression in human meniscal lesions
-
Cucchiarini, M., Schetting, S., Terwilliger, E.F., Kohn, D., and Madry, H. rAAV-mediated overexpression of FGF-2 promotes cell proliferation, survival, and alpha-SMA expression in human meniscal lesions. Gene Ther 16, 1363, 2009.
-
(2009)
Gene Ther
, vol.16
, pp. 1363
-
-
Cucchiarini, M.1
Schetting, S.2
Terwilliger, E.F.3
Kohn, D.4
Madry, H.5
-
58
-
-
75649099043
-
Hypertrophy is induced during the in vitro chondrogenic differentiation of human mesenchymal stem cells by bone morphogenetic protein-2 and bone morphogenetic protein-4 gene transfer
-
Steinert, A.F., Proffen, B., Kunz, M., Hendrich, C., Ghivizzani, S.C., Nö th, U., Rethwilm, A., Eulert, J., and Evans, C.H. Hypertrophy is induced during the in vitro chondrogenic differentiation of human mesenchymal stem cells by bone morphogenetic protein-2 and bone morphogenetic protein-4 gene transfer. Arthritis Res Ther 11, R148, 2009.
-
(2009)
Arthritis Res Ther
, vol.11
-
-
Steinert, A.F.1
Proffen, B.2
Kunz, M.3
Hendrich, C.4
Ghivizzani, S.C.5
Nö Th, U.6
Rethwilm, A.7
Eulert, J.8
Evans, C.H.9
-
59
-
-
67649565425
-
Gene and protein expression profile of naive and osteo-chondrogenically differentiated rat bone marrow-derived mesenchymal progenitor cells
-
Grä ssel, S., Ahmed, N., Gottl, C., and Grifka, J. Gene and protein expression profile of naive and osteo-chondrogenically differentiated rat bone marrow-derived mesenchymal progenitor cells. Int J MolMed 23, 745, 2009.
-
(2009)
Int J MolMed
, vol.23
, pp. 745
-
-
Grä Ssel, S.1
Ahmed, N.2
Gottl, C.3
Grifka, J.4
-
60
-
-
61649106341
-
Interleukin-1beta and tumor necrosis factor alpha inhibit chondrogenesis by human mesenchymal stem cells through NF-kappaBdependent pathways
-
Wehling, N., Palmer, G.D., Pilapil, C., Liu, F., Wells, J.W., Mü ller, P.E., Evans, C.H., and Porter, R.M. Interleukin-1beta and tumor necrosis factor alpha inhibit chondrogenesis by human mesenchymal stem cells through NF-kappaBdependent pathways. Arthritis Rheum 60, 801, 2009.
-
(2009)
Arthritis Rheum
, vol.60
, pp. 801
-
-
Wehling, N.1
Palmer, G.D.2
Pilapil, C.3
Liu, F.4
Wells, J.W.5
Mü Ller, P.E.6
Evans, C.H.7
Porter, R.M.8
-
61
-
-
0027467887
-
Regulation of growthplate chondrocytes by insulin-like growth-factor i and basic fibroblast growth factor
-
Trippel, S.B., Wroblewski, J., Makower, A.M., Whelan, M.C., Schoenfeld, D., and Doctrow, S.R. Regulation of growthplate chondrocytes by insulin-like growth-factor I and basic fibroblast growth factor. J Bone Joint Surg Am 75, 177, 1993.
-
(1993)
J Bone Joint Surg Am
, vol.75
, pp. 177
-
-
Trippel, S.B.1
Wroblewski, J.2
Makower, A.M.3
Whelan, M.C.4
Schoenfeld, D.5
Doctrow, S.R.6
-
62
-
-
0028914071
-
Inhibitory effects of basic fibroblast growth factor on chondrocyte differentiation
-
Wroblewski, J., and Edwall-Arvidsson, C. Inhibitory effects of basic fibroblast growth factor on chondrocyte differentiation. J Bone Miner Res 10, 735, 1995.
-
(1995)
J Bone Miner Res
, vol.10
, pp. 735
-
-
Wroblewski, J.1
Edwall-Arvidsson, C.2
-
63
-
-
77049109633
-
Fibroblast growth factor receptors in in vitro and in vivo chondrogenesis: Relating tissue engineering using adult mesenchymal stem cells to embryonic development
-
Hellingman, C.A., Koevoet, W., Kops, N., Farrell, E., Jahr, H., Liu, W., Baatenburg de Jong, R.J., Frenz, D.A., and von Osch, G.J. Fibroblast growth factor receptors in in vitro and in vivo chondrogenesis: relating tissue engineering using adult mesenchymal stem cells to embryonic development. Tissue Eng Part A 16, 545, 2010.
-
(2010)
Tissue Eng Part A
, vol.16
, pp. 545
-
-
Hellingman, C.A.1
Koevoet, W.2
Kops, N.3
Farrell, E.4
Jahr, H.5
Liu, W.6
Baatenburg De Jong, R.J.7
Frenz, D.A.8
Von Osch, G.J.9
-
64
-
-
0030678549
-
Osf2/Cbfa1: A transcriptional activator of osteoblast differentiation
-
Ducy, P., Zhang, R., Geoffroy, V., Ridall, A.L., and Karsenty, G. Osf2/Cbfa1: a transcriptional activator of osteoblast differentiation. Cell 89, 747, 1997.
-
(1997)
Cell
, vol.89
, pp. 747
-
-
Ducy, P.1
Zhang, R.2
Geoffroy, V.3
Ridall, A.L.4
Karsenty, G.5
-
65
-
-
4344628054
-
Repair of articular cartilage defects in rabbits using CDMP1 gene-transfected autologous mesenchymal cells derived from bone marrow
-
Katayama, R., Wakitani, S., Tsumaki, N., Morita, Y., Matsushita, I., Gejo, R., and Kimura, T. Repair of articular cartilage defects in rabbits using CDMP1 gene-transfected autologous mesenchymal cells derived from bone marrow. Rheumatology 43, 980, 2004.
-
(2004)
Rheumatology
, vol.43
, pp. 980
-
-
Katayama, R.1
Wakitani, S.2
Tsumaki, N.3
Morita, Y.4
Matsushita, I.5
Gejo, R.6
Kimura, T.7
-
66
-
-
77953811664
-
In vivo restoration of full-thickness cartilage defects by poly(lactide-co-glycolide) sponges filled with fibrin gel, bone marrow mesenchymal stem cells and DNA complexes
-
Wang, W., Li, B., Li, Y., Jiang, Y., Ouyang, H., and Gao, C. In vivo restoration of full-thickness cartilage defects by poly(lactide-co-glycolide) sponges filled with fibrin gel, bone marrow mesenchymal stem cells and DNA complexes. Biomaterials 31, 5953, 2010.
-
(2010)
Biomaterials
, vol.31
, pp. 5953
-
-
Wang, W.1
Li, B.2
Li, Y.3
Jiang, Y.4
Ouyang, H.5
Gao, C.6
-
67
-
-
28244498360
-
Determination of osteoprogenitor-specific promoter activity in mouse mesenchymal stem cells by recombinant adeno-associated virus transduction
-
Kumar, S., Mahendra, G., and Ponnazhagan, S. Determination of osteoprogenitor-specific promoter activity in mouse mesenchymal stem cells by recombinant adeno-associated virus transduction. Biochim Biophys Acta 1731, 95, 2005.
-
(2005)
Biochim Biophys Acta
, vol.1731
, pp. 95
-
-
Kumar, S.1
Mahendra, G.2
Ponnazhagan, S.3
-
68
-
-
0033779509
-
Cartilage and bone regeneration using gene-enhanced tissue engineering
-
Mason, J.M., Breitbart, A.S., Barcia, M., Porti, D., Pergolizzi, R.G., and Grande, D.A. Cartilage and bone regeneration using gene-enhanced tissue engineering. Clin Orthop Relat Res 379 Suppl, S171, 2000.
-
(2000)
Clin Orthop Relat Res
, vol.379
, Issue.SUPPL.
-
-
Mason, J.M.1
Breitbart, A.S.2
Barcia, M.3
Porti, D.4
Pergolizzi, R.G.5
Grande, D.A.6
-
69
-
-
0037331874
-
Articular cartilage repair by gene therapy using growth factor-producing mesenchymal cells
-
Gelse, K., von der Mark, K., Aigner, T., Park, J., and Schneider, H. Articular cartilage repair by gene therapy using growth factor-producing mesenchymal cells. Arthritis Rheum 48, 430, 2003.
-
(2003)
Arthritis Rheum
, vol.48
, pp. 430
-
-
Gelse, K.1
Von Der Mark, K.2
Aigner, T.3
Park, J.4
Schneider, H.5
-
70
-
-
23744467071
-
Enhanced repair of articular cartilage defects in vivo by transplanted chondrocytes overexpressing insulin-like growth factor i (IGF-I)
-
Madry, H., Kaul, G., Cucchiarini, M., Stein, U., Zurakowski, D., Remberger, K., Menger, M.D., Kohn, D., and Trippel, S.B. Enhanced repair of articular cartilage defects in vivo by transplanted chondrocytes overexpressing insulin-like growth factor I (IGF-I). Gene Ther 12, 1171, 2005.
-
(2005)
Gene Ther
, vol.12
, pp. 1171
-
-
Madry, H.1
Kaul, G.2
Cucchiarini, M.3
Stein, U.4
Zurakowski, D.5
Remberger, K.6
Menger, M.D.7
Kohn, D.8
Trippel, S.B.9
-
71
-
-
32444449516
-
Cartilage repair using bone morphogenetic protein 4 and muscle-derived stem cells
-
Kuroda, R., Usas, A., Kubo, S., Corsi, K., Peng, H., Rose, T., Cummins, J., Fu, F.H., and Huard, J. Cartilage repair using bone morphogenetic protein 4 and muscle-derived stem cells. Arthritis Rheum 54, 433, 2006.
-
(2006)
Arthritis Rheum
, vol.54
, pp. 433
-
-
Kuroda, R.1
Usas, A.2
Kubo, S.3
Corsi, K.4
Peng, H.5
Rose, T.6
Cummins, J.7
Fu, F.H.8
Huard, J.9
-
72
-
-
34250699624
-
Genetic modification of chondrocytes with insulin-like growth factor-1 enhances cartilage healing in an equine model
-
Goodrich, L.R., Hidaka, C., Robbins, P.D., Evans, C.H., and Nixon, A.J. Genetic modification of chondrocytes with insulin-like growth factor-1 enhances cartilage healing in an equine model. J Bone Joint Surg Br 89, 672, 2007.
-
(2007)
J Bone Joint Surg Br
, vol.89
, pp. 672
-
-
Goodrich, L.R.1
Hidaka, C.2
Robbins, P.D.3
Evans, C.H.4
Nixon, A.J.5
-
73
-
-
77953476884
-
Articular cartilage repair by genetically modified bone marrow aspirate in sheep
-
Ivkovic, A., Pascher, A., Hudetz, D., Maticic, D., Jelic, M., Dickinson, S., Loparic, M., Haspl, M., Windhagen, R., and Pecina, M. Articular cartilage repair by genetically modified bone marrow aspirate in sheep. Gene 17, 779, 2010.
-
(2010)
Gene
, vol.17
, pp. 779
-
-
Ivkovic, A.1
Pascher, A.2
Hudetz, D.3
Maticic, D.4
Jelic, M.5
Dickinson, S.6
Loparic, M.7
Haspl, M.8
Windhagen, R.9
Pecina, M.10
-
74
-
-
33744489059
-
Regional gene therapy for full-thickness articular cartilage lesions using naked DNA with a collagen matrix
-
Di Cesare, P.E., Frenkel, S.R., Carlson, C.S., Fang, C., and Liu, C. Regional gene therapy for full-thickness articular cartilage lesions using naked DNA with a collagen matrix. J Orthop Res 24, 1118, 2006.
-
(2006)
J Orthop Res
, vol.24
, pp. 1118
-
-
Di Cesare, P.E.1
Frenkel, S.R.2
Carlson, C.S.3
Fang, C.4
Liu, C.5
-
75
-
-
34548382159
-
IL-1ra/IGF-1 gene therapy modulates repair of microfractured chondral defects
-
Morisset, S., Frisbie, D.D., Robbins, P.D., Nixon, A.J., and McIlwraith, C.W. IL-1ra/IGF-1 gene therapy modulates repair of microfractured chondral defects. Clin Orthop Relat Res 462, 221, 2007.
-
(2007)
Clin Orthop Relat Res
, vol.462
, pp. 221
-
-
Morisset, S.1
Frisbie, D.D.2
Robbins, P.D.3
Nixon, A.J.4
McIlwraith, C.W.5
|