Effects of adenovirus-mediated bFGF, IL-1Ra and IGF-1 gene transfer on human osteoarthritic chondrocytes and osteoarthritis in rabbits

Experimental and Molecular Medicine

Volumn 42, Issue 10, 2010, Pages 684-695

  Chen, Biao ^a   Qin, Jun ^a   Wang, Hui ^b   Magdalou, Jacques ^c   Chen, Liaobin ^a  

^a WUHAN UNIVERSITY   (China)

^b WUHAN UNIVERSITY   (China)

^c UNIVERSITÉ DE LORRAINE   (France)

Author keywords

Chondrocytes; Fibroblast growth factor 2; Gene therapy; Genetic; Insulin like growth factor i; Interleukin 1 receptor antagonist protein; Osteoarthritis; Transduction

Indexed keywords

ADENOVIRUS VECTOR; AGGRECANASE 2; BASIC FIBROBLAST GROWTH FACTOR; COLLAGEN TYPE 2; COLLAGENASE 3; GLYCOSAMINOGLYCAN; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; SOMATOMEDIN C; STROMELYSIN; TISSUE INHIBITOR OF METALLOPROTEINASE 1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTERIOR CRUCIATE LIGAMENT INJURY; ARTICLE; CARTILAGE CELL; CELL PROLIFERATION; COLLAGEN SYNTHESIS; CONTROLLED STUDY; DISEASE MODEL; DRUG EFFICACY; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; IN VIVO STUDY; NONHUMAN; OSTEOARTHRITIS; PROTEIN EXPRESSION; RABBIT; SUPERNATANT; SYNOVIAL FLUID; TREATMENT OUTCOME; VIRAL GENE DELIVERY SYSTEM;

ADENOVIRIDAE; ORYCTOLAGUS CUNICULUS;

EID: 78149265290     PISSN: 12263613     EISSN: 20926413     Source Type: Journal    
DOI: 10.3858/emm.2010.42.10.067     Document Type: Article

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