Dual transduction of insulin-like growth factor-I and interleukin-1 receptor antagonist protein controls cartilage degradation in an osteoarthritic culture model

Journal of Orthopaedic Research

Volumn 23, Issue 1, 2005, Pages 118-126

  Haupt, Jennifer L ^a   Frisbie, David D ^b   McIlwraith, C Wayne ^b   Robbins, Paul D ^c   Ghivizzani, Steve ^d   Evans, Chris H ^d   Nixon, Alan J ^a  

^a Department of Obstetrics Gynecology   (United States)

^b Department of Environmental and Radiological Health Sciences   (United States)

^c UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^d HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Cartilage repair; Gene therapy; IGF I; IL 1Ra; Synovium

Indexed keywords

ADENOVIRUS VECTOR; COLLAGEN TYPE 2; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; MATRIX METALLOPROTEINASE; PROTEOGLYCAN; RECOMBINANT INTERLEUKIN 1BETA; RNA; SOMATOMEDIN C; TOLONIUM CHLORIDE;

ANIMAL TISSUE; ARTICLE; CARTILAGE DEGENERATION; CELL CULTURE; CONTROLLED STUDY; DNA DETERMINATION; GENE THERAPY; HORSE; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; NONHUMAN; OSTEOARTHRITIS; PRIORITY JOURNAL; PROTEIN CONTENT; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN SECRETION; PROTEIN SYNTHESIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SYNOVIOCYTE; SYNOVIUM; WOUND HEALING;

ANIMALS; CARTILAGE; DNA; GENE THERAPY; HORSES; INSULIN-LIKE GROWTH FACTOR I; INTERLEUKIN 1 RECEPTOR ANTAGONIST PROTEIN; OSTEOARTHRITIS; PROTEOGLYCANS; RNA, MESSENGER; SIALOGLYCOPROTEINS; TISSUE CULTURE TECHNIQUES;

EID: 11044221899     PISSN: 07360266     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.orthres.2004.06.020     Document Type: Article

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