-
1
-
-
15844390942
-
Pathogenesis and management of pain in osteoarthritis
-
Dieppe, P. A. & Lohmander, L. S. Pathogenesis and management of pain in osteoarthritis. Lancet 365, 965-973 (2005).
-
(2005)
Lancet
, vol.365
, pp. 965-973
-
-
Dieppe, P.A.1
Lohmander, L.S.2
-
2
-
-
38149052992
-
Estimates of the prevalence of arthritis and other rheumatic conditions in the United States. Part II
-
Lawrence, R. C. et al. Estimates of the prevalence of arthritis and other rheumatic conditions in the United States. Part II. Arthritis Rheum. 58, 26-35 (2008).
-
(2008)
Arthritis Rheum.
, vol.58
, pp. 26-35
-
-
Lawrence, R.C.1
-
3
-
-
32544454827
-
Total joint replacement in osteoarthritis
-
Katz, J. N. Total joint replacement in osteoarthritis. Best Pract. Res. Clin. Rheumatol. 20, 145-153 (2006).
-
(2006)
Best Pract. Res. Clin. Rheumatol.
, vol.20
, pp. 145-153
-
-
Katz, J.N.1
-
4
-
-
84924833491
-
Osteoarthritis of the hip: A study of the nature and evolution of the disease
-
Harrison, M. H., Shajowicz, F. & Trueta, J. Osteoarthritis of the hip: a study of the nature and evolution of the disease. J. Bone Joint Surg. Br. 35B, 598-626 (1953).
-
(1953)
J. Bone Joint Surg. Br.
, vol.35 B
, pp. 598-626
-
-
Harrison, M.H.1
Shajowicz, F.2
Trueta, J.3
-
5
-
-
58849145676
-
Finding genes underlying human disease
-
Stein, C. M. & Elston, R. C. Finding genes underlying human disease. Clin. Genet. 75, 101-106 (2009).
-
(2009)
Clin. Genet.
, vol.75
, pp. 101-106
-
-
Stein, C.M.1
Elston, R.C.2
-
6
-
-
77956361934
-
Involvement of different risk factors are involved in clinically severe large joint osteoarthritis according to the presence of hand interphalangeal nodes
-
Valdes, A. M. et al. Involvement of different risk factors are involved in clinically severe large joint osteoarthritis according to the presence of hand interphalangeal nodes. Arthritis Rheum. 62, 2688-2695 (2010).
-
(2010)
Arthritis Rheum.
, vol.62
, pp. 2688-2695
-
-
Valdes, A.M.1
-
7
-
-
59649093445
-
A functional polymorphism in the catechol-O-methyltransferase gene is associated with osteoarthritis-related pain
-
van Meurs, J. B. et al. A functional polymorphism in the catechol-O-methyltransferase gene is associated with osteoarthritis-related pain. Arthritis Rheum. 60, 628-629 (2009).
-
(2009)
Arthritis Rheum.
, vol.60
, pp. 628-629
-
-
Van Meurs, J.B.1
-
8
-
-
75749110202
-
A genome-wide association study identifies an osteoarthritis susceptibility locus on chromosome 7q22
-
Kerkhof, H. J. et al. A genome-wide association study identifies an osteoarthritis susceptibility locus on chromosome 7q22. Arthritis Rheum. 62, 499-510 (2010).
-
(2010)
Arthritis Rheum.
, vol.62
, pp. 499-510
-
-
Kerkhof, H.J.1
-
9
-
-
54949138784
-
Polymorphisms in the interleukin-1 receptor antagonist and interleukin-6 genes affect risk of osteolysis in patients with total hip arthroplasty
-
Gordon, A., Kiss-Toth, E., Stockley, I., Eastell, R. & Wilkinson, J. M. Polymorphisms in the interleukin-1 receptor antagonist and interleukin-6 genes affect risk of osteolysis in patients with total hip arthroplasty. Arthritis Rheum. 58, 3157-3165 (2008).
-
(2008)
Arthritis Rheum.
, vol.58
, pp. 3157-3165
-
-
Gordon, A.1
Kiss-Toth, E.2
Stockley, I.3
Eastell, R.4
Wilkinson, J.M.5
-
10
-
-
77951758095
-
Report of the American College of Rheumatology Pain Management Task Force
-
Borenstein, D. et al. Report of the American College of Rheumatology Pain Management Task Force. Arthritis Care Res. 62, 590-599 (2010).
-
(2010)
Arthritis Care Res.
, vol.62
, pp. 590-599
-
-
Borenstein, D.1
-
11
-
-
62349115224
-
Radiologic markers of osteoarthritis progression
-
Hunter, D. J., Le Graverand, M. P. & Eckstein, F. Radiologic markers of osteoarthritis progression. Curr. Opin. Rheumatol. 21, 110-117 (2009).
-
(2009)
Curr. Opin. Rheumatol.
, vol.21
, pp. 110-117
-
-
Hunter, D.J.1
Le Graverand, M.P.2
Eckstein, F.3
-
12
-
-
77950429077
-
Pain perception is altered by a nucleotide polymorphism in SCN9A
-
Reimann, F. et al. Pain perception is altered by a nucleotide polymorphism in SCN9A. Proc. Natl Acad. Sci. USA 107, 5148-5153 (2010).
-
(2010)
Proc. Natl Acad. Sci. USA
, vol.107
, pp. 5148-5153
-
-
Reimann, F.1
-
13
-
-
0344237255
-
Genetic contribution to cartilage volume in women: A classical twin study
-
Hunter, D. J., Snieder, H., March, L. & Sambrook, P. N. Genetic contribution to cartilage volume in women: a classical twin study. Rheumatology (Oxford) 42, 1495-1500 (2003).
-
(2003)
Rheumatology (Oxford)
, vol.42
, pp. 1495-1500
-
-
Hunter, D.J.1
Snieder, H.2
March, L.3
Sambrook, P.N.4
-
14
-
-
25444491939
-
The genetic contribution to longitudinal changes in knee structure and muscle strength: A sibpair study
-
Zhai, G., Ding, C., Stankovich, J., Cicuttini, F. & Jones, G. The genetic contribution to longitudinal changes in knee structure and muscle strength: a sibpair study. Arthritis Rheum. 52, 2830-2834 (2005).
-
(2005)
Arthritis Rheum.
, vol.52
, pp. 2830-2834
-
-
Zhai, G.1
Ding, C.2
Stankovich, J.3
Cicuttini, F.4
Jones, G.5
-
15
-
-
33846401119
-
Genetic influence on the progression of radiographic knee osteoarthritis, a longitudinal twin study
-
Zhai, G., Hart, D. J., Kato, B. S., MacGregor, A. & Spector, T. D. Genetic influence on the progression of radiographic knee osteoarthritis, a longitudinal twin study. Osteoarthritis Cartilage 15, 222-225 (2007).
-
(2007)
Osteoarthritis Cartilage
, vol.15
, pp. 222-225
-
-
Zhai, G.1
Hart, D.J.2
Kato, B.S.3
MacGregor, A.4
Spector, T.D.5
-
16
-
-
0034638651
-
Assessment of a genetic contribution to osteoarthritis of the hip: Sibling study
-
Lanyon, P., Muir, K., Doherty, S. & Doherty, M. Assessment of a genetic contribution to osteoarthritis of the hip: sibling study. BMJ 321, 1179-1183 (2000).
-
(2000)
BMJ
, vol.321
, pp. 1179-1183
-
-
Lanyon, P.1
Muir, K.2
Doherty, S.3
Doherty, M.4
-
17
-
-
4344697342
-
Genetic risk of knee osteoarthritis, a sibling study
-
Neame, R. L., Muir, K., Doherty, S. & Doherty, M. Genetic risk of knee osteoarthritis, a sibling study. Ann. Rheum. Dis. 63, 1022-1027 (2004).
-
(2004)
Ann. Rheum. Dis.
, vol.63
, pp. 1022-1027
-
-
Neame, R.L.1
Muir, K.2
Doherty, S.3
Doherty, M.4
-
18
-
-
0030786608
-
Genetic influences in end-stage osteoarthritis. Sibling risks of hip and knee replacement for idiopathic osteoarthritis
-
Chitnavis, J. et al. Genetic influences in end-stage osteoarthritis. Sibling risks of hip and knee replacement for idiopathic osteoarthritis. J. Bone Joint Surg. Br. 79, 660-664 (1997).
-
(1997)
J. Bone Joint Surg. Br.
, vol.79
, pp. 660-664
-
-
Chitnavis, J.1
-
19
-
-
35848934474
-
Hip joint replacement surgery for idiopathic osteoarthritis aggregates in families
-
Bukulmez, H. et al. Hip joint replacement surgery for idiopathic osteoarthritis aggregates in families. Arthritis Res. Ther. 8, R25 (2006).
-
(2006)
Arthritis Res. Ther.
, vol.8
-
-
Bukulmez, H.1
-
20
-
-
34548213205
-
Genetic influences in the aetiology of anteromedial osteoarthritis of the knee
-
McDonnell, S. M., Sinsheimer, J., Price, A. J. & Carr, A. J. Genetic influences in the aetiology of anteromedial osteoarthritis of the knee. J. Bone Joint Surg. Br. 89, 901-903 (2007).
-
(2007)
J. Bone Joint Surg. Br.
, vol.89
, pp. 901-903
-
-
McDonnell, S.M.1
Sinsheimer, J.2
Price, A.J.3
Carr, A.J.4
-
21
-
-
33748685243
-
Osteoarthritis susceptibility loci defined by genome scan meta-analysis
-
Lee, Y. H., Rho, Y. H., Choi, S. J., Ji, J. D. & Song, G. G. Osteoarthritis susceptibility loci defined by genome scan meta-analysis. Rheumatol. Int. 26, 996-1000 (2006).
-
(2006)
Rheumatol. Int.
, vol.26
, pp. 996-1000
-
-
Lee, Y.H.1
Rho, Y.H.2
Choi, S.J.3
Ji, J.D.4
Song, G.G.5
-
22
-
-
44849113821
-
Identification of DIO2 as a new susceptibility locus for symptomatic osteoarthritis
-
Meulenbelt, I. et al. Identification of DIO2 as a new susceptibility locus for symptomatic osteoarthritis. Hum. Mol. Genet. 17, 1867-1875 (2008).
-
(2008)
Hum. Mol. Genet.
, vol.17
, pp. 1867-1875
-
-
Meulenbelt, I.1
-
24
-
-
77951237955
-
Genetics in neuroendocrine immunology: Implications for rheumatoid arthritis and osteoarthritis
-
Stark, K., Straub, R. H., Blazicková, S., Hengstenberg, C. & Rovenský, J. Genetics in neuroendocrine immunology: implications for rheumatoid arthritis and osteoarthritis. Ann. NY Acad. Sci. 1193, 10-14 (2010).
-
Ann. NY Acad. Sci.
, vol.1193
, pp. 10-14
-
-
Stark, K.1
Straub, R.H.2
Blazicková, S.3
Hengstenberg, C.4
Rovenský, J.5
-
25
-
-
64349091037
-
SNP imputation in association studies
-
Halperin, E. & Stephan, D. A. SNP imputation in association studies. Nat. Biotechnol. 27, 349-351 (2009).
-
(2009)
Nat. Biotechnol.
, vol.27
, pp. 349-351
-
-
Halperin, E.1
Stephan, D.A.2
-
26
-
-
60549083544
-
An open access database of genome-wide association results
-
Johnson, A. D. & ODonnell, C. J. An open access database of genome-wide association results. BMC Med. Genet. 10, 6 (2009).
-
(2009)
BMC Med. Genet.
, vol.10
, pp. 6
-
-
Johnson, A.D.1
Odonnell, C.J.2
-
27
-
-
77951702343
-
Genetic heterogeneity in human disease
-
McClellan, J. & King, M. C. Genetic heterogeneity in human disease. Cell 141, 210-217 (2010).
-
(2010)
Cell
, vol.141
, pp. 210-217
-
-
McClellan, J.1
King, M.C.2
-
30
-
-
59949097546
-
-
HuGE Navigator [online]
-
HuGE literature finder. HuGE Navigator [online], http://hugenavigator. net/HuGENavigator/ startPagePubLit.do (2010)
-
(2010)
HuGE Literature Finder
-
-
-
31
-
-
51449114435
-
Calibration of credibility of agnostic genome-wide associations
-
Ioannidis, J. P. Calibration of credibility of agnostic genome-wide associations. Am. J. Med. Genet. B Neuropsychiatr. Genet. 147B, 964-972 (2008).
-
(2008)
Am. J. Med. Genet. B Neuropsychiatr. Genet.
, vol.147 B
, pp. 964-972
-
-
Ioannidis, J.P.1
-
32
-
-
42949118331
-
Joint homeostasis, restoration, and remodeling in osteoarthritis
-
Lories, R. J. Joint homeostasis, restoration, and remodeling in osteoarthritis. Best Pract. Res. Clin. Rheumatol. 22, 209-220 (2008).
-
(2008)
Best Pract. Res. Clin. Rheumatol.
, vol.22
, pp. 209-220
-
-
Lories, R.J.1
-
33
-
-
0032905901
-
Mechanisms of GDF-5 action during skeletal development
-
Francis-West, P. H. et al. Mechanisms of GDF-5 action during skeletal development. Development 126, 1305-1315 (1999).
-
(1999)
Development
, vol.126
, pp. 1305-1315
-
-
Francis-West, P.H.1
-
34
-
-
34047103363
-
A functional polymorphism in the 5′ UTR of GDF5 is associated with susceptibility to osteoarthritis
-
Miyamoto, Y. et al. A functional polymorphism in the 5′ UTR of GDF5 is associated with susceptibility to osteoarthritis. Nat. Genet. 39, 529-533 (2007).
-
(2007)
Nat. Genet.
, vol.39
, pp. 529-533
-
-
Miyamoto, Y.1
-
35
-
-
67650074525
-
Functional analysis of the osteoarthritis susceptibility-associated GDF5 regulatory polymorphism
-
Egli, R. J. et al. Functional analysis of the osteoarthritis susceptibility-associated GDF5 regulatory polymorphism. Arthritis Rheum. 60, 2055-2064 (2009).
-
(2009)
Arthritis Rheum.
, vol.60
, pp. 2055-2064
-
-
Egli, R.J.1
-
36
-
-
72249115093
-
Association of the DVWA and GDF5 polymorphisms with osteoarthritis in UK populations
-
Valdes, A. M. et al. Association of the DVWA and GDF5 polymorphisms with osteoarthritis in UK populations. Ann. Rheum. Dis. 68, 1916-1920 (2009).
-
(2009)
Ann. Rheum. Dis.
, vol.68
, pp. 1916-1920
-
-
Valdes, A.M.1
-
37
-
-
66449089103
-
Large-scale analysis of association between GDF5 and FRZB variants and osteoarthritis of the hip, knee, and hand
-
Evangelou, E. et al. Large-scale analysis of association between GDF5 and FRZB variants and osteoarthritis of the hip, knee, and hand. Arthritis Rheum. 60, 1710-1721 (2009).
-
(2009)
Arthritis Rheum.
, vol.60
, pp. 1710-1721
-
-
Evangelou, E.1
-
38
-
-
43049122786
-
A meta-analysis of European and Asian cohorts reveals a global role of a functional SNP in the 5′ UTR of GDF5 with osteoarthritis susceptibility
-
Chapman, K. et al. A meta-analysis of European and Asian cohorts reveals a global role of a functional SNP in the 5′ UTR of GDF5 with osteoarthritis susceptibility. Hum. Mol. Genet. 17, 1497-1504 (2008).
-
(2008)
Hum. Mol. Genet.
, vol.17
, pp. 1497-1504
-
-
Chapman, K.1
-
39
-
-
70449729925
-
Genetic variation in the GDF5 region is associated with osteoarthritis, height, hip axis length and fracture risk: The Rotterdam study
-
Vaes, R. B. et al. Genetic variation in the GDF5 region is associated with osteoarthritis, height, hip axis length and fracture risk: the Rotterdam study. Ann. Rheum. Dis. 68, 1754-1760 (2009).
-
(2009)
Ann. Rheum. Dis.
, vol.68
, pp. 1754-1760
-
-
Vaes, R.B.1
-
40
-
-
78650988509
-
The GDF5 rs143383 polymorphism is associated with osteoarthritis of the knee with genome-wide statistical significance
-
doi:10.1136/ard.2010.134155
-
Valdes, A. M. et al. The GDF5 rs143383 polymorphism is associated with osteoarthritis of the knee with genome-wide statistical significance. Ann. Rheum. Dis. doi:10.1136/ ard.2010.134155.
-
Ann. Rheum. Dis.
-
-
Valdes, A.M.1
-
41
-
-
44949190537
-
Lessons from animal models of osteoarthritis
-
van den Berg, W. B. Lessons from animal models of osteoarthritis. Curr. Rheumatol. Rep. 10, 26-29 (2008).
-
(2008)
Curr. Rheumatol. Rep.
, vol.10
, pp. 26-29
-
-
Van Den Berg, W.B.1
-
42
-
-
13944259791
-
An aspartic acid repeat polymorphism in asporin inhibits chondrogenesis and increases susceptibility to osteoarthritis
-
Kizawa, H. et al. An aspartic acid repeat polymorphism in asporin inhibits chondrogenesis and increases susceptibility to osteoarthritis. Nat. Genet. 37, 138-144 (2005).
-
(2005)
Nat. Genet.
, vol.37
, pp. 138-144
-
-
Kizawa, H.1
-
43
-
-
33751300226
-
Replication of the association of the aspartic acid repeat polymorphism in the asporin gene with knee-osteoarthritis susceptibility in Han Chinese
-
Jiang, Q. et al. Replication of the association of the aspartic acid repeat polymorphism in the asporin gene with knee-osteoarthritis susceptibility in Han Chinese. J. Hum. Genet. 51, 1068-1072 (2006).
-
(2006)
J. Hum. Genet.
, vol.51
, pp. 1068-1072
-
-
Jiang, Q.1
-
44
-
-
34547093391
-
Association of the aspartic acidrepeat polymorphism in the asporin gene with age at onset of knee osteoarthritis in Han Chinese population
-
Shi, D. et al. Association of the aspartic acidrepeat polymorphism in the asporin gene with age at onset of knee osteoarthritis in Han Chinese population. J. Hum. Genet. 52, 664-667 (2007).
-
(2007)
J. Hum. Genet.
, vol.52
, pp. 664-667
-
-
Shi, D.1
-
45
-
-
42749087329
-
Aspartic acid repeat polymorphism of the asporin gene with susceptibility to osteoarthritis of the knee in a Korean population
-
Song, J. H. et al. Aspartic acid repeat polymorphism of the asporin gene with susceptibility to osteoarthritis of the knee in a Korean population. Knee 15, 191-195 (2008).
-
(2008)
Knee
, vol.15
, pp. 191-195
-
-
Song, J.H.1
-
46
-
-
50949126590
-
Absence of association of asporin polymorphisms and osteoarthritis susceptibility in US Caucasians
-
Atif, U. et al. Absence of association of asporin polymorphisms and osteoarthritis susceptibility in US Caucasians. Osteoarthritis Cartilage 16, 1174-1177 (2008).
-
(2008)
Osteoarthritis Cartilage
, vol.16
, pp. 1174-1177
-
-
Atif, U.1
-
47
-
-
34547790324
-
Meta-analysis of association between the ASPN D-repeat and osteoarthritis
-
Nakamura, T. et al. Meta-analysis of association between the ASPN D-repeat and osteoarthritis. Hum. Mol. Genet. 16, 1676-1681 (2007).
-
(2007)
Hum. Mol. Genet.
, vol.16
, pp. 1676-1681
-
-
Nakamura, T.1
-
48
-
-
0035795409
-
TGF-α/Smad3 signals repress chondrocyte hypertrophic differentiation and are required for maintaining articular cartilage
-
Yang, X. et al. TGF-α/Smad3 signals repress chondrocyte hypertrophic differentiation and are required for maintaining articular cartilage. J. Cell Biol. 153, 35-46 (2001).
-
(2001)
J. Cell Biol.
, vol.153
, pp. 35-46
-
-
Yang, X.1
-
49
-
-
77955365705
-
Genetic variation in the SMAD3 gene is associated with hip and knee osteoarthritis
-
Valdes, A. M. et al. Genetic variation in the SMAD3 gene is associated with hip and knee osteoarthritis. Arthritis Rheum. 62, 2347-2352 (2010).
-
(2010)
Arthritis Rheum.
, vol.62
, pp. 2347-2352
-
-
Valdes, A.M.1
-
50
-
-
29644432280
-
Smad3-deficient chondrocytes have enhanced BMP signaling and accelerated differentiation
-
Li, T. F. et al. Smad3-deficient chondrocytes have enhanced BMP signaling and accelerated differentiation. J. Bone Miner. Res. 21, 4-16 (2006).
-
(2006)
J. Bone Miner. Res.
, vol.21
, pp. 4-16
-
-
Li, T.F.1
-
51
-
-
59649110626
-
TSH-based protocol, tablet instability, and absorption effects on L-T4 bioequivalence
-
Eisenberg, M. & Distefano, J. J. TSH-based protocol, tablet instability, and absorption effects on L-T4 bioequivalence. Thyroid 19, 103-110 (2009).
-
(2009)
Thyroid
, vol.19
, pp. 103-110
-
-
Eisenberg, M.1
Distefano, J.J.2
-
52
-
-
78650667173
-
Meta-analyses of genes modulating intracellular T3 bio-availability reveal a possible role for the DIO3 gene in osteoarthritis susceptibility
-
doi:10.1136/ard.2010.133660
-
Meulenbelt, I. et al. Meta-analyses of genes modulating intracellular T3 bio-availability reveal a possible role for the DIO3 gene in osteoarthritis susceptibility. Ann. Rheum. Dis. doi:10.1136/ard.2010.133660.
-
Ann. Rheum. Dis.
-
-
Meulenbelt, I.1
-
53
-
-
27744597628
-
Extracellular superoxide dismutase and oxidant damage in osteoarthritis
-
Regan, E. et al. Extracellular superoxide dismutase and oxidant damage in osteoarthritis. Arthritis Rheum. 52, 3479-3491 (2005).
-
(2005)
Arthritis Rheum.
, vol.52
, pp. 3479-3491
-
-
Regan, E.1
-
54
-
-
33847194975
-
Cell death and apoptosis in osteoarthritic cartilage
-
Kim, H. A. & Blanco, F. J. Cell death and apoptosis in osteoarthritic cartilage. Curr. Drug Targets 8, 333-345 (2007).
-
(2007)
Curr. Drug Targets
, vol.8
, pp. 333-345
-
-
Kim, H.A.1
Blanco, F.J.2
-
55
-
-
67650065023
-
Variation at the ANP32A gene is associated with risk of hip osteoarthritis in women
-
Valdes, A. M. et al. Variation at the ANP32A gene is associated with risk of hip osteoarthritis in women. Arthritis Rheum. 60, 2046-2054 (2009).
-
(2009)
Arthritis Rheum.
, vol.60
, pp. 2046-2054
-
-
Valdes, A.M.1
-
56
-
-
73449139779
-
The role of European mtDNA haplogroups in the prevalence of hip osteoarthritis in Galicia, Northern Spain
-
Rego, I. et al. The role of European mtDNA haplogroups in the prevalence of hip osteoarthritis in Galicia, Northern Spain. Ann. Rheum. Dis. 69, 210-213 (2010).
-
(2010)
Ann. Rheum. Dis.
, vol.69
, pp. 210-213
-
-
Rego, I.1
-
57
-
-
49449096411
-
Mitochondrial DNA haplogroups, role in the prevalence and severity of knee osteoarthritis
-
Rego-Pérez, I., Fernández-Moreno, M., Fernández- Lpez, C., Arenas, J. & Blanco, F. J. Mitochondrial DNA haplogroups, role in the prevalence and severity of knee osteoarthritis. Arthritis Rheum. 58, 2387-2396 (2008).
-
(2008)
Arthritis Rheum.
, vol.58
, pp. 2387-2396
-
-
Rego-Pérez, I.1
Fernández-Moreno, M.2
Fernández-Lpez, C.3
Arenas, J.4
Blanco, F.J.5
-
58
-
-
77954411692
-
A COL2A1 gene polymorphism is related with advanced stages of osteoarthritis of the knee in Mexican Mestizo population
-
Gálvez-Rosas, A. et al. A COL2A1 gene polymorphism is related with advanced stages of osteoarthritis of the knee in Mexican Mestizo population. Rheumatol. Int. 30, 1035-1039 (2010)
-
(2010)
Rheumatol. Int.
, vol.30
, pp. 1035-1039
-
-
Gálvez-Rosas, A.1
-
59
-
-
77957263965
-
Large-scale gene expression in bone marrow mesenchymal stem cells: A putative role for COL10A1 in osteoarthritis
-
Lamas, J. R. et al. Large-scale gene expression in bone marrow mesenchymal stem cells: a putative role for COL10A1 in osteoarthritis. Ann. Rheum. Dis. 69, 1880-1885 (2010).
-
(2010)
Ann. Rheum. Dis.
, vol.69
, pp. 1880-1885
-
-
Lamas, J.R.1
-
60
-
-
69949143486
-
The knee osteoarthritis susceptibility locus DVWA on chromosome 3p24.3 is the 5′ part of the split COL6A4 gene
-
Wagener, R., Gara, S. K., Kobbe, B., Paulsson, M. & Zaucke, F. The knee osteoarthritis susceptibility locus DVWA on chromosome 3p24.3 is the 5′ part of the split COL6A4 gene. Matrix Biol. 28, 307-310 (2009).
-
(2009)
Matrix Biol.
, vol.28
, pp. 307-310
-
-
Wagener, R.1
Gara, S.K.2
Kobbe, B.3
Paulsson, M.4
Zaucke, F.5
-
61
-
-
48349105759
-
Common variants in DVWA on chromosome 3p24.3 are associated with susceptibility to knee osteoarthritis
-
Miyamoto, Y. et al. Common variants in DVWA on chromosome 3p24.3 are associated with susceptibility to knee osteoarthritis. Nat. Genet. 40, 994-998 (2008).
-
(2008)
Nat. Genet.
, vol.40
, pp. 994-998
-
-
Miyamoto, Y.1
-
62
-
-
64549151355
-
Large replication study and meta-analyses of DVWA as an osteoarthritis susceptibility locus in European and Asian populations
-
Meulenbelt, I. et al. Large replication study and meta-analyses of DVWA as an osteoarthritis susceptibility locus in European and Asian populations. Hum. Mol. Genet. 18, 1518-1523 (2009).
-
(2009)
Hum. Mol. Genet.
, vol.18
, pp. 1518-1523
-
-
Meulenbelt, I.1
-
63
-
-
66149180583
-
Developments in the scientific understanding of osteoarthritis
-
Abramson, S. B. & Attur, M. Developments in the scientific understanding of osteoarthritis. Arthritis Res. Ther. 11, 227 (2009).
-
(2009)
Arthritis Res. Ther.
, vol.11
, pp. 227
-
-
Abramson, S.B.1
Attur, M.2
-
64
-
-
57049092882
-
The contribution of genes to osteoarthritis
-
Valdes, A. M. & Spector, T. D. The contribution of genes to osteoarthritis. Med. Clin. North Am. 93, 45-66 (2009).
-
(2009)
Med. Clin. North Am.
, vol.93
, pp. 45-66
-
-
Valdes, A.M.1
Spector, T.D.2
-
65
-
-
77952551250
-
A meta-analysis of interleukin-6 promoter polymorphisms on risk of hip and knee osteoarthritis
-
Valdes, A. M. et al. A meta-analysis of interleukin-6 promoter polymorphisms on risk of hip and knee osteoarthritis. Osteoarthritis Cartilage 18, 699-704 (2010).
-
(2010)
Osteoarthritis Cartilage
, vol.18
, pp. 699-704
-
-
Valdes, A.M.1
-
66
-
-
77951590246
-
Radiographic severity of knee osteoarthritis is conditional on interleukin 1 receptor antagonist gene variations
-
Attur, M. et al. Radiographic severity of knee osteoarthritis is conditional on interleukin 1 receptor antagonist gene variations. Ann. Rheum. Dis. 69, 856-861 (2010).
-
(2010)
Ann. Rheum. Dis.
, vol.69
, pp. 856-861
-
-
Attur, M.1
-
67
-
-
35148849760
-
Lack of association polymorphisms of the IL1RN, IL1A, and IL1B genes with knee osteoarthritis in Turkish patients
-
Sezgin, M. et al. Lack of association polymorphisms of the IL1RN, IL1A, and IL1B genes with knee osteoarthritis in Turkish patients. Clin. Invest. Med. 30, E86-E92 (2007).
-
(2007)
Clin. Invest. Med.
, vol.30
-
-
Sezgin, M.1
-
68
-
-
41849104564
-
Interleukin-1beta gene polymorphism associated with radiographic signs of osteoarthritis of the knee
-
Kanoh, T. et al. Interleukin-1beta gene polymorphism associated with radiographic signs of osteoarthritis of the knee. J. Orthop. Sci. 13, 97-100 (2008).
-
(2008)
J. Orthop. Sci.
, vol.13
, pp. 97-100
-
-
Kanoh, T.1
-
69
-
-
69049113951
-
Genetic polymorphisms of interleukin-1beta (-511C/T) and interleukin-1 receptor antagonist (86-bpVNTR) in susceptibility to knee osteoarthritis in a Chinese Han population
-
Ni, H. et al. Genetic polymorphisms of interleukin-1beta (-511C/T) and interleukin-1 receptor antagonist (86-bpVNTR) in susceptibility to knee osteoarthritis in a Chinese Han population. Rheumatol. Int. 29, 1301-1305 (2009).
-
(2009)
Rheumatol. Int.
, vol.29
, pp. 1301-1305
-
-
Ni, H.1
-
70
-
-
44449153906
-
Genome-wide association scan identifies a prostaglandin-endoperoxide synthase 2 variant involved in risk of knee osteoarthritis
-
Valdes, A. M. et al. Genome-wide association scan identifies a prostaglandin-endoperoxide synthase 2 variant involved in risk of knee osteoarthritis. Am. J. Hum. Genet. 82, 1231-1240 (2008).
-
(2008)
Am. J. Hum. Genet.
, vol.82
, pp. 1231-1240
-
-
Valdes, A.M.1
-
71
-
-
78650968063
-
The (-765 G-> C) promoter variant of the COX-2/PTGS2 gene is associated with a lower risk for end-stage hip and knee osteoarthritis
-
doi:10.1136/ard.2009.124040
-
Schneider, E. M. et al. The (-765 G->C) promoter variant of the COX-2/PTGS2 gene is associated with a lower risk for end-stage hip and knee osteoarthritis. Ann. Rheum. Dis. doi:10.1136/ard.2009.124040.
-
Ann. Rheum. Dis.
-
-
Schneider, E.M.1
-
72
-
-
78149408549
-
New sequence variants in HLA class II/III region associated with susceptibility to knee osteoarthritis identified by genome-wide association study
-
Nakajima, M. et al. New sequence variants in HLA class II/III region associated with susceptibility to knee osteoarthritis identified by genome-wide association study. PLoS ONE 5, e9723 (2010).
-
(2010)
PLoS ONE
, vol.5
-
-
Nakajima, M.1
-
73
-
-
33847059993
-
The role of T cells in the pathogenesis of osteoarthritis
-
Sakkas, L. I. & Platsoucas, C. D. The role of T cells in the pathogenesis of osteoarthritis. Arthritis Rheum. 56, 409-424 (2007).
-
(2007)
Arthritis Rheum.
, vol.56
, pp. 409-424
-
-
Sakkas, L.I.1
Platsoucas, C.D.2
-
74
-
-
78149489455
-
Serum C reactive protein levels and genetic variation in the CRP gene are not associated with the prevalence, incidence or progression of osteoarthritis independent of body mass index
-
doi:10.1136/ard.2009.125260
-
Kerkhof, H. J. et al. Serum C reactive protein levels and genetic variation in the CRP gene are not associated with the prevalence, incidence or progression of osteoarthritis independent of body mass index. Ann. Rheum. Dis. doi:10.1136/ard.2009.125260.
-
Ann. Rheum. Dis.
-
-
Kerkhof, H.J.1
-
75
-
-
57249115817
-
Tumour necrosis factor alpha -308G/A gene polymorphism: Lack of association with knee osteoarthritis in a Turkish population
-
Sezgin, M. et al. Tumour necrosis factor alpha -308G/A gene polymorphism: lack of association with knee osteoarthritis in a Turkish population. Clin. Exp. Rheumatol. 26, 763-768 (2008).
-
(2008)
Clin. Exp. Rheumatol.
, vol.26
, pp. 763-768
-
-
Sezgin, M.1
-
76
-
-
0033864484
-
Dual roles of Wnt signaling during chondrogenesis in the chicken limb
-
Hartmann, C. & Tabin, C. J. Dual roles of Wnt signaling during chondrogenesis in the chicken limb. Development 127, 3141-3159 (2000).
-
(2000)
Development
, vol.127
, pp. 3141-3159
-
-
Hartmann, C.1
Tabin, C.J.2
-
77
-
-
53849125461
-
Wnt-beta-catenin signaling in the pathogenesis of osteoarthritis
-
Corr, M. Wnt-beta-catenin signaling in the pathogenesis of osteoarthritis. Nat. Clin. Pract. Rheumatol. 4, 550-556 (2008).
-
(2008)
Nat. Clin. Pract. Rheumatol.
, vol.4
, pp. 550-556
-
-
Corr, M.1
-
78
-
-
20944450269
-
Haplotypes of the lowdensity lipoprotein receptor-related protein 5 (LRP5) gene: Are they a risk factor in osteoarthritis?
-
Smith, A. J. et al. Haplotypes of the lowdensity lipoprotein receptor-related protein 5 (LRP5) gene: are they a risk factor in osteoarthritis? Osteoarthritis Cartilage 13, 608-613 (2005).
-
(2005)
Osteoarthritis Cartilage
, vol.13
, pp. 608-613
-
-
Smith, A.J.1
-
79
-
-
48349084103
-
Radiographic osteoarthritis at three joint sites and FRZB, LRP5, and LRP6 polymorphisms in two population-based cohorts
-
Kerkhof, J. M. et al. Radiographic osteoarthritis at three joint sites and FRZB, LRP5, and LRP6 polymorphisms in two population-based cohorts. Osteoarthritis Cartilage 16, 1141-1149 (2008).
-
(2008)
Osteoarthritis Cartilage
, vol.16
, pp. 1141-1149
-
-
Kerkhof, J.M.1
-
80
-
-
33646372430
-
Frizzled-related protein variants are risk factors for hip osteoarthritis
-
Lane, N. E. et al. Frizzled-related protein variants are risk factors for hip osteoarthritis. Arthritis Rheum. 54, 1246-1254 (2006).
-
(2006)
Arthritis Rheum.
, vol.54
, pp. 1246-1254
-
-
Lane, N.E.1
-
81
-
-
33846236311
-
Sex and ethnic differences in the association of ASPN, CALM1, COL2A1, COMP, and FRZB with genetic susceptibility to osteoarthritis of the knee
-
Valdes, A. M. et al. Sex and ethnic differences in the association of ASPN, CALM1, COL2A1, COMP, and FRZB with genetic susceptibility to osteoarthritis of the knee. Arthritis Rheum. 56, 137-146 (2007).
-
(2007)
Arthritis Rheum.
, vol.56
, pp. 137-146
-
-
Valdes, A.M.1
-
82
-
-
0348111255
-
The usual suspects: Verdict not guilty?
-
Tortorella, M. D. & Malfait, A. M. The usual suspects: verdict not guilty? Arthritis Rheum. 48, 3304-3307 (2003).
-
(2003)
Arthritis Rheum.
, vol.48
, pp. 3304-3307
-
-
Tortorella, M.D.1
Malfait, A.M.2
-
83
-
-
15844384854
-
ADAMTS5 is the major aggrecanase in mouse cartilage in vivo and in vitro
-
Stanton, H. et al. ADAMTS5 is the major aggrecanase in mouse cartilage in vivo and in vitro. Nature 434, 648-652 (2005).
-
(2005)
Nature
, vol.434
, pp. 648-652
-
-
Stanton, H.1
-
84
-
-
39749178970
-
Genetic variation including nonsynonymous polymorphisms of a major aggrecanase, ADAMTS-5, in susceptibility to osteoarthritis
-
Rodriguez-Lopez, J. et al. Genetic variation including nonsynonymous polymorphisms of a major aggrecanase, ADAMTS-5, in susceptibility to osteoarthritis. Arthritis Rheum. 58, 435-441 (2008).
-
(2008)
Arthritis Rheum.
, vol.58
, pp. 435-441
-
-
Rodriguez-Lopez, J.1
-
85
-
-
60249087668
-
Association of a nsSNP in ADAMTS14 to some osteoarthritis phenotypes
-
Rodriguez-Lopez, J. et al. Association of a nsSNP in ADAMTS14 to some osteoarthritis phenotypes. Osteoarthritis Cartilage 17, 321-327 (2009).
-
(2009)
Osteoarthritis Cartilage
, vol.17
, pp. 321-327
-
-
Rodriguez-Lopez, J.1
-
86
-
-
59449104607
-
Association of (-1, 607) 1G/2G polymorphism of matrix metalloproteinase-1 gene with knee osteoarthritis in the Turkish population (knee osteoarthritis and MMPs gene polymorphisms)
-
Barlas, I. O. et al. Association of (-1,607) 1G/2G polymorphism of matrix metalloproteinase-1 gene with knee osteoarthritis in the Turkish population (knee osteoarthritis and MMPs gene polymorphisms). Rheumatol. Int. 29, 383-388 (2009).
-
(2009)
Rheumatol. Int.
, Issue.29
, pp. 383-388
-
-
Barlas, I.O.1
-
87
-
-
67650407473
-
Missense single nucleotide polymorphism of the ADAM12 gene is associated with radiographic knee osteoarthritis in middle-aged Estonian cohort
-
Kerna, I. et al. Missense single nucleotide polymorphism of the ADAM12 gene is associated with radiographic knee osteoarthritis in middle-aged Estonian cohort. Osteoarthritis Cartilage 17, 1093-1098 (2009).
-
(2009)
Osteoarthritis Cartilage
, vol.17
, pp. 1093-1098
-
-
Kerna, I.1
-
88
-
-
32444433647
-
Reproducible genetic associations between candidate genes and clinical knee osteoarthritis in men and women
-
Valdes, A. M. et al. Reproducible genetic associations between candidate genes and clinical knee osteoarthritis in men and women. Arthritis Rheum. 54, 533-539 (2006).
-
(2006)
Arthritis Rheum.
, vol.54
, pp. 533-539
-
-
Valdes, A.M.1
-
89
-
-
17044364069
-
Estrogen receptor-alpha gene haplotype is associated with primary knee osteoarthritis in Korean population
-
Jin, S. Y. et al. Estrogen receptor-alpha gene haplotype is associated with primary knee osteoarthritis in Korean population. Arthritis Res. Ther. 6, R415-R421 (2004).
-
(2004)
Arthritis Res. Ther.
, vol.6
-
-
Jin, S.Y.1
-
91
-
-
34547676850
-
Estrogen receptor alpha genotype is associated with a reduced prevalence of radiographic hip osteoarthritis in elderly Caucasian women
-
Lian, K. et al. Estrogen receptor alpha genotype is associated with a reduced prevalence of radiographic hip osteoarthritis in elderly Caucasian women. Osteoarthritis Cartilage 15, 972-978 (2007).
-
(2007)
Osteoarthritis Cartilage
, vol.15
, pp. 972-978
-
-
Lian, K.1
-
92
-
-
67349122665
-
Attempt to replicate published genetic associations in a large, welldefined osteoarthritis case-control population (the GOAL study)
-
Limer, K. L. et al. Attempt to replicate published genetic associations in a large, welldefined osteoarthritis case-control population (the GOAL study). Osteoarthritis Cartilage 17, 782-789 (2009).
-
(2009)
Osteoarthritis Cartilage
, vol.17
, pp. 782-789
-
-
Limer, K.L.1
-
93
-
-
44849087738
-
A functional SNP in EDG2 increases susceptibility to knee osteoarthritis in Japanese
-
Mototani, H. et al. A functional SNP in EDG2 increases susceptibility to knee osteoarthritis in Japanese. Hum. Mol. Genet. 17, 1790-1797 (2008).
-
(2008)
Hum. Mol. Genet.
, vol.17
, pp. 1790-1797
-
-
Mototani, H.1
-
94
-
-
67449128720
-
Testing the druggable endothelial differentiation gene 2 knee osteoarthritis genetic factor for replication in a wide range of sample collections
-
Dieguez-Gonzalez, R. et al. Testing the druggable endothelial differentiation gene 2 knee osteoarthritis genetic factor for replication in a wide range of sample collections. Ann. Rheum. Dis. 68, 1017-1021 (2009).
-
(2009)
Ann. Rheum. Dis.
, vol.68
, pp. 1017-1021
-
-
Dieguez-Gonzalez, R.1
-
95
-
-
55449101697
-
Association of KLOTHO gene polymorphisms with knee osteoarthritis in Greek population
-
Tsezou, A. et al. Association of KLOTHO gene polymorphisms with knee osteoarthritis in Greek population. J. Orthop. Res. 26, 1466-1470 (2008).
-
(2008)
J. Orthop. Res.
, vol.26
, pp. 1466-1470
-
-
Tsezou, A.1
-
96
-
-
34548400346
-
New emerging role of pitx1 transcription factor in osteoarthritis pathogenesis
-
Picard, C., Azeddine, B., Moldovan, F., Martel- Pelletier, J. & Moreau, A. New emerging role of pitx1 transcription factor in osteoarthritis pathogenesis. Clin. Orthop. Relat. Res. 462, 59-66 (2007).
-
(2007)
Clin. Orthop. Relat. Res.
, vol.462
, pp. 59-66
-
-
Picard, C.1
Azeddine, B.2
Moldovan, F.3
Martel- Pelletier, J.4
Moreau, A.5
-
97
-
-
78650977422
-
Genetic polymorphism of PITX1 in susceptibility to knee osteoarthritis in a Chinese Han population: A case-control study
-
doi:10.1007/s00296-009-1341-5
-
Fan, J. et al. Genetic polymorphism of PITX1 in susceptibility to knee osteoarthritis in a Chinese Han population: a case-control study. Rheumatol. Int. doi:10.1007/s00296-009- 1341-5.
-
Rheumatol. Int.
-
-
Fan, J.1
-
98
-
-
20244378239
-
A functional single nucleotide polymorphism in the core promoter region of CALM1 is associated with hip osteoarthritis in Japanese
-
Mototani, H. et al. A functional single nucleotide polymorphism in the core promoter region of CALM1 is associated with hip osteoarthritis in Japanese. Hum. Mol. Genet. 14, 1009-1017 (2005).
-
(2005)
Hum. Mol. Genet.
, vol.14
, pp. 1009-1017
-
-
Mototani, H.1
-
99
-
-
45549102864
-
Association of the CALM1 core promoter polymorphism with knee osteoarthritis in patients of Greek origin
-
Poulou, M. et al. Association of the CALM1 core promoter polymorphism with knee osteoarthritis in patients of Greek origin. Genet. Test. 12, 263-265 (2008).
-
(2008)
Genet. Test.
, vol.12
, pp. 263-265
-
-
Poulou, M.1
-
100
-
-
55349091075
-
Lack of association between the CALM1 core promoter polymorphism (-16C/T) and susceptibility to knee osteoarthritis in a Chinese Han population
-
Shi, D. et al. Lack of association between the CALM1 core promoter polymorphism (-16C/T) and susceptibility to knee osteoarthritis in a Chinese Han population. BMC Med. Genet. 9, 91 (2008).
-
(2008)
BMC Med. Genet.
, vol.9
, pp. 91
-
-
Shi, D.1
-
101
-
-
77956929106
-
Identification of sequence polymorphisms in CALM2 and analysis of association with hip osteoarthritis in a Japanese population
-
Mototani, H., Iida, A., Nakamura, Y. & Ikegawa, S. Identification of sequence polymorphisms in CALM2 and analysis of association with hip osteoarthritis in a Japanese population. J. Bone Miner. Metab. 28, 547-553 (2010).
-
(2010)
J. Bone Miner. Metab.
, vol.28
, pp. 547-553
-
-
Mototani, H.1
Iida, A.2
Nakamura, Y.3
Ikegawa, S.4
-
102
-
-
0037927980
-
Angiotensin converting enzyme gene polymorphism in Korean patients with primary knee osteoarthritis
-
Hong, S. J. et al. Angiotensin converting enzyme gene polymorphism in Korean patients with primary knee osteoarthritis. Exp. Mol. Med. 35, 189-195 (2003).
-
(2003)
Exp. Mol. Med.
, vol.35
, pp. 189-195
-
-
Hong, S.J.1
-
103
-
-
79951577923
-
DD genotype of ace gene I/D polymorphism is associated in a Turkish study population with osteoarthritis
-
doi:10.1007/s11033-010-0284-y
-
Bayram, B. et al. DD genotype of ace gene I/D polymorphism is associated in a Turkish study population with osteoarthritis. Mol. Biol. Rep. doi:10.1007/s11033-010-0284-y.
-
Mol. Biol. Rep.
-
-
Bayram, B.1
-
104
-
-
43349083503
-
Prevalence of angiotensinconverting enzyme gene insertion-deletion polymorphism in patients with primary knee osteoarthritis
-
Shehab, D. K. et al. Prevalence of angiotensinconverting enzyme gene insertion-deletion polymorphism in patients with primary knee osteoarthritis. Clin. Exp. Rheumatol. 26, 305-310 (2008).
-
(2008)
Clin. Exp. Rheumatol.
, vol.26
, pp. 305-310
-
-
Shehab, D.K.1
-
105
-
-
36549027898
-
Calcitonin affects both bone and cartilage: A dual action treatment for osteoarthritis?
-
Karsdal, M. A. et al. Calcitonin affects both bone and cartilage: a dual action treatment for osteoarthritis? Ann. NY Acad. Sci. 1117, 181-195 (2007).
-
(2007)
Ann. NY Acad. Sci.
, vol.1117
, pp. 181-195
-
-
Karsdal, M.A.1
-
106
-
-
75149135554
-
Association of the calcitonin gene (CA) polymorphism with osteoarthritis of the knee in a Mexican mestizo population
-
Magaña, J. J. et al. Association of the calcitonin gene (CA) polymorphism with osteoarthritis of the knee in a Mexican mestizo population. Knee 17, 157-160 (2010).
-
(2010)
Knee
, vol.17
, pp. 157-160
-
-
Magaña, J.J.1
-
107
-
-
77955176134
-
Getting to the heart of the matter: Osteoarthritis takes its place as part of the metabolic syndrome
-
Katz, J. D., Agrawal, S. & Velasquez, M. Getting to the heart of the matter: osteoarthritis takes its place as part of the metabolic syndrome. Curr. Opin. Rheumatol. 22, 512-519 (2010)
-
(2010)
Curr. Opin. Rheumatol.
, vol.22
, pp. 512-519
-
-
Katz, J.D.1
Agrawal, S.2
Velasquez, M.3
-
108
-
-
77955176027
-
Local leptin production in osteoarthritis subchondral osteoblasts may be responsible for their abnormal phenotypic expression
-
Mutabaruka, M. S., Aoulad Aissa, M., Delalandre, A., Lavigne, M. & Lajeunesse, D. Local leptin production in osteoarthritis subchondral osteoblasts may be responsible for their abnormal phenotypic expression. Arthritis Res. Ther. 12, R20 (2010).
-
(2010)
Arthritis Res. Ther.
, vol.12
-
-
Mutabaruka, M.S.1
Aoulad Aissa, M.2
Delalandre, A.3
Lavigne, M.4
Lajeunesse, D.5
-
109
-
-
78049293809
-
Association of the leptin gene with knee osteoarthritis susceptibility in a Han Chinese population: A case-control study
-
doi:10.1038/jhg.2010.86
-
Qin, J. et al. Association of the leptin gene with knee osteoarthritis susceptibility in a Han Chinese population: a case-control study. J. Hum. Genet. doi:10.1038/jhg.2010.86.
-
J. Hum. Genet.
-
-
Qin, J.1
-
110
-
-
53149094308
-
Increase levels of apo-A1 and apo B are associated in knee osteoarthritis: Lack of association with VEGF -460 T/C and +405 C/G polymorphisms
-
Sánchez-Enrquez, S. et al. Increase levels of apo-A1 and apo B are associated in knee osteoarthritis: lack of association with VEGF -460 T/C and +405 C/G polymorphisms. Rheumatol. Int. 29, 63-68 (2008)
-
(2008)
Rheumatol. Int.
, vol.29
, pp. 63-68
-
-
Sánchez-Enrquez, S.1
-
111
-
-
44449135139
-
Association of single-nucleotide polymorphisms in RHOB and TXNDC3 with knee osteoarthritis susceptibility: Two case-control studies in East Asian populations and a metaanalysis
-
Shi, D. et al. Association of single-nucleotide polymorphisms in RHOB and TXNDC3 with knee osteoarthritis susceptibility: two case-control studies in East Asian populations and a metaanalysis. Arthritis Res. Ther. 10, R54 (2008).
-
(2008)
Arthritis Res. Ther.
, vol.10
-
-
Shi, D.1
-
112
-
-
38549178090
-
Lack of association of single nucleotide polymorphism in LRCH1 with knee osteoarthritis susceptibility
-
Jiang, Q. et al. Lack of association of single nucleotide polymorphism in LRCH1 with knee osteoarthritis susceptibility. J. Hum. Genet. 53, 42-47 (2008).
-
(2008)
J. Hum. Genet.
, vol.53
, pp. 42-47
-
-
Jiang, Q.1
-
113
-
-
78751703383
-
Meta-analysis of genomewide association studies confirms a susceptibility locus for knee osteoarthritis on chromosome 7q22
-
in press
-
Evangelou, E. et al. Meta-analysis of genomewide association studies confirms a susceptibility locus for knee osteoarthritis on chromosome 7q22. Ann. Rheum. Dis. (in press).
-
Ann. Rheum. Dis.
-
-
Evangelou, E.1
-
114
-
-
77952557918
-
Missing heritability and strategies for finding the underlying causes of complex disease
-
Eichler, E. E. et al. Missing heritability and strategies for finding the underlying causes of complex disease. Nat. Rev. Genet. 11, 446-450 (2010).
-
(2010)
Nat. Rev. Genet.
, vol.11
, pp. 446-450
-
-
Eichler, E.E.1
-
115
-
-
37749024290
-
The additive effect of individual genes in predicting risk of knee osteoarthritis
-
Valdes, A. M., Doherty, M. & Spector, T. D. The additive effect of individual genes in predicting risk of knee osteoarthritis. Ann. Rheum. Dis. 67, 124-127 (2008).
-
(2008)
Ann. Rheum. Dis.
, vol.67
, pp. 124-127
-
-
Valdes, A.M.1
Doherty, M.2
Spector, T.D.3
-
116
-
-
77957728949
-
Prediction model for knee osteoarthritis based on genetic and clinical information
-
Takahashi, H. et al. Prediction model for knee osteoarthritis based on genetic and clinical information. Arthritis Res. Ther. 12, R187 (2010).
-
(2010)
Arthritis Res. Ther.
, vol.12
-
-
Takahashi, H.1
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