Untangling the role of tau in Alzheimer's disease: A unifying hypothesis

Translational Neuroscience

Volumn 4, Issue 2, 2013, Pages 115-133

  Bhatia, Neha ^a   Hall, Garth F ^a  

^a UNIVERSITY OF MASSACHUSETTS LOWELL   (United States)

Author keywords

Alzheimer's disease pathogenesis; Neurodegeneration; Secretion; Tau lesion spread; Tauopathy; Tauopathy hypothesis; Tauopathy models

Indexed keywords

AMYLOID; AMYLOID BETA PROTEIN; BETA SECRETASE; GAMMA SECRETASE; MEMBRANE PROTEIN; PRESENILIN 1; PRESENILIN 2; TAU PROTEIN; AMYLOID PRECURSOR PROTEIN;

ALZHEIMER DISEASE; AMINO TERMINAL SEQUENCE; AMYLOID CASCADE HYPOTHESIS; AXONAL INJURY; BINDING AFFINITY; CARBOXY TERMINAL SEQUENCE; CELL CYCLE; CELL CYCLE REGULATION; CELL LEVEL; CELL LOSS; CELL MEMBRANE; CELL MIGRATION; CELL POLARITY; CELL TRANSFER; CONCEPTUAL FRAMEWORK; CYTOPATHOLOGY; DEGENERATIVE DISEASE; DENDRITIC SPINE; DISEASE ACTIVITY; DISEASE ASSOCIATION; DOWN SYNDROME; ENVIRONMENTAL FACTOR; EXON; GENE MUTATION; GENETIC ANALYSIS; GENETIC RISK; HEAD INJURY; HUMAN; HYPOTHESIS; INTRON; MEDICAL RESEARCH; MOLECULAR MECHANICS; NERVE CELL DEGENERATION; NERVE CELL DIFFERENTIATION; NEUROFIBRILLARY TANGLE; NEUROTOXICITY; NEUROTRANSMISSION; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN BLOOD LEVEL; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PROTEIN SECRETION; PROTEIN TRANSPORT; REVIEW; RISK ASSESSMENT; RISK FACTOR; SIGNAL TRANSDUCTION; TAUOPATHY; TRANSCYTOSIS; AGING; APOPTOSIS; ARTICLE; BRAIN INJURY; CELL DEDIFFERENTIATION; CHROMOSOME 21; CYTOTOXICITY; DENDRITE; DISEASE COURSE; ENDOCYTOSIS; GENE DOSAGE; MICROTUBULE; NERVE DEGENERATION; NERVE FIBER; NERVE FIBER TRANSECTION; NEUROPATHOLOGY; OLIGOMERIZATION; POINT MUTATION; PRION; PRION DISEASE; PROTEIN PROTEIN INTERACTION; SPORT INJURY; SYNAPSE;

EID: 84885045781     PISSN: 20813856     EISSN: 20816936     Source Type: Journal    
DOI: 10.2478/s13380-013-0114-5     Document Type: Review

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