Aβ and tau form soluble complexes that may promote self aggregation of both into the insoluble forms in Alzheimer's diseases

Proceedings of the National Academy of Sciences of the United States of America

Volumn 103, Issue 6, 2006, Pages 1953-1958

  Guo, Jian Ping ^a   Arai, Tetsuaki ^b   Miklossy, Judit ^a   McGeer, Patrick L ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE   (Japan)

Author keywords

Immunochemistry; Neurofibrillary tangles; Senile plaques; Surface plasmon resonance

Indexed keywords

AMYLOID BETA PROTEIN; GLYCOGEN SYNTHASE KINASE 3BETA; SERINE; TAU PROTEIN; THREONINE; MULTIPROTEIN COMPLEX;

AGED; ALZHEIMER DISEASE; ARTICLE; BINDING AFFINITY; COMPLEX FORMATION; CONFOCAL MICROSCOPY; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; NEUROFIBRILLARY TANGLE; PATHOGENESIS; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; SENILE PLAQUE; SURFACE PLASMON RESONANCE; WESTERN BLOTTING; AMINO ACID SEQUENCE; CELL MEMBRANE; CHEMISTRY; METABOLISM; MOLECULAR GENETICS; PATHOLOGY; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN MICROARRAY; SOLUBILITY;

AGED; AGED, 80 AND OVER; ALZHEIMER DISEASE; AMINO ACID SEQUENCE; AMYLOID BETA-PROTEIN; CELL MEMBRANE; ENZYME-LINKED IMMUNOSORBENT ASSAY; HUMANS; IMMUNOHISTOCHEMISTRY; MOLECULAR SEQUENCE DATA; MULTIPROTEIN COMPLEXES; PHOSPHORYLATION; PROTEIN ARRAY ANALYSIS; PROTEIN BINDING; SOLUBILITY; SURFACE PLASMON RESONANCE; TAU PROTEINS;

EID: 32444432146     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0509386103     Document Type: Article

References (33)

1. Iqbal, K., Alonso Adel, C., Chen, S., Cholan, M. O., El-Akkad, E., Gong, C. X., Khatoon, S., Li, B., Liu, F., Rahman, A., et al. (2005) Biochim. Biophys. Acta 1739, 198-210.
2. Hardy, J. A. & Higgins, G. A. (1992) Science 256, 184-185.
3. Hardy, J. & Selkoe, D. J. (2002) Science 297, 353-356.
4. Hutton, M. (2002) Movement Disorders 17, 1402-1403.
5. Goedert, M. & Jakes, R. (2005) Biochim. Biophys. Acta 1739, 240-250.
6. Arai, T., Guo, J. P. & McGeer, P. L. (2005) J. Biol. Chem. 280, 5145-5153.
7. Guo, J. P., Petric, M., Campbell, W. & McGeer, P. L. (2004) Virology 324, 251-256.
8. Jonsson, U., Fagerstam, L., Ivarsson, B., Johnsson, B., Karlsson, R., Lundh, K., Lofas, S., Persson, B.. Roos, H., Ronnberg, I., et al. (1991) BioTechniques 11, 620-627.
9. Hasegawa, K., Ono, K., Yamada, M. & Naiki, H. (2002) Biochemistry 41, 13489-13498.
10. Rank, K. B., Pauley, A. M., Bhattacharya, K., Wang, Z., Evans, D. B., Fleck, T. J., Johnston, J. A. & Sharma, S. K. (2002) FEBS Lett. 514, 263-268.
11. Kang, J., Lemaire, H. G., Unterbeck, A., Salbaum, J. M., Masters, C. L., Grzeschik, K. H., Multhaup, G., Beyreuther, K. & Muller-Hill, B. (1987) Nature 325, 733-736.
12. McGeer, P. L., Akiyama, H., Kawamata, T., Yamada, T., Walker, D. G. & Ishii, T. (1992) J. Neurosci. Res. 31, 428-442.
13. Benowitz, L. I., Rodriguez, W., Paskevich, P., Mufson, E. J., Schenk, D. & Neve, R. L. (1989) Exp. Neurol. 106, 237-250.
14. Cole, G. M., Masliah, E., Shelton, E. R., Chan, H. W., Terry, R. D. & Saitoh, T. (1991) Neurobiol. Aging 12, 85-91.
15. Card, J. P., Meade, R. P. & Davis, L. G. (1988) Neuron 1, 835-846.
16. Shivers, B. D., Hilbich, C., Multhaup, G., Salbaum, M., Beyreuther, K. & Seeburg, P. H. (1988) EMBO J. 7, 1365-1370.
17. D'Andrea, M. R., Nagele, R. G., Wang, H. Y., Peterson, P. A. & Lee, D. H. (2001) Histopathology 38, 120-134.
18. Greenfield, J. P., Tsai, J., Gouras, G. K., Hai, B., Thinakaran, G., Checler, F., Sisodia, S. S., Greengard, P. & Xu, H. (1999) Proc. Natl. Acad. Sci. USA 96, 742-747.
19. Takahashi, R. H., Milner, T. A., Li, F., Nam, E. E., Edgar, M. A., Yamaguchi, H., Beal, M. F., Xu, H., Greengard, P. & Gouras, G. K. (2002) Am. J. Pathol. 161, 1869-1879.
20. Gouras, G. K., Tsai, J., Naslund, J., Vincent, B., Edgar, M., Checler, F., Greenfield, J. F., Haroutunian, V., Buxbaum, J. D., Xu, H., et al. (2000) Am. J. Pathol. 156, 15-20.
21. Gyure, K. A., Durham, R., Stewart, W. F., Smialek, J. E. & Troncoso, J. C. (2001) Arch. Pathol. Lab. Med. 125, 489-492.
22. Xu, H., Sweeney, D., Wang, R., Thinakaran, G., Lo, A. C., Sisodia, S. S., Greengard, P. & Gandy, S. (1997) Proc. Natl. Acad. Sci. USA 94, 3748-3752.
23. Skovronsky, D. M., Doms, R. W. & Lee, V. M. (1998) J. Cell Biol. 141, 1031-1039.
24. Cook, D. G., Forman, M. S., Sung, J. C., Leight, S., Kolson, D. L., Iwatsubo, T., Lee, V. M. & Doms, R. W. (1997) Nat. Med. 3, 1021-1023.
25. Wild-Bode, C., Yamazaki, T., Capell, A., Leimer, U., Steiner, H., Ihara, Y. & Haass, C. (1997) J. Biol. Chem. 272, 16085-16088.
26. Hartmann, T., Bieger, S. C., Bruhl, B., Tienari, P. J., Ida, N., Allsop, D., Roberts, G. W., Masters, C. L., Dotti, C. G., Unsicker, K., et al. (1997) Nat. Med. 3, 1016-1020.
27. Piccini, A., Russo, C., Gliozzi, A., Relini, A., Vitali, A., Borghi, R., Giliberto, L., Armirotti, A., D'Arrigo, C., Bachi, A., et al. (2005) J. Biol. Chem. 280, 34186-34192.
28. Tabaton, M. & Piccini, A. (2005) Int. J. Exp. Pathol. 86, 139-145.
29. Lue, F., Kuo, Y., Roher, A. E., Brachova L., Shen, Y., Sue, L., Beach, T., Kurth, J. H., Rydel, R. E. & Rogers, J. (1999) Am. J. Pathol. 155, 853-862.
30. LaFerla, F. M., Troncoso, J. C., Strickland, D. K., Kawas, C. H. & Jay, G. (1997) J. Clin. Invest. 100, 310-320.
31. Grundke-Iqbal, I., Iqbal, K., George, L., Tung, Y. C, Kim, K. S. & Wisniewski, H. M. (1989) Proc. Natl Acad. Sci. USA. 86, 2853-2857.
32. Giasson, B. I., Forman, M. S., Higuchi, M., Golbe, L. I., Graves, C. L., Kotzbauer, P. T., Trojanowski, J. Q. & Lee, V. M. (2003) Science 300, 636-640.
33. Gotz, J., Chen, F., vanDorpe, J. & Nitsch, R. M. (2001) Science 293, 1446-1447.