메뉴 건너뛰기




Volumn 26, Issue 3, 2005, Pages 373-382

Endosome function and dysfunction in Alzheimer's disease and other neurodegenerative diseases

Author keywords

ALS; Amyloid; APP; Endosomes; Huntington disease; Lysosomes

Indexed keywords

AMYLOID PRECURSOR PROTEIN; PROTEIN DERIVATIVE;

EID: 11444267601     PISSN: 01974580     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neurobiolaging.2004.09.018     Document Type: Conference Paper
Times cited : (324)

References (137)
  • 1
    • 0029346911 scopus 로고
    • The abnormal isoform of the prion protein accumulates in late-endosome-like organelles in scrapie-infected mouse brain
    • J.E. Arnold, C. Tipler, L. Laszlo, J. Hope, M. Landon, and R.J. Mayer The abnormal isoform of the prion protein accumulates in late-endosome-like organelles in scrapie-infected mouse brain J Pathol 176 1995 403 411
    • (1995) J Pathol , vol.176 , pp. 403-411
    • Arnold, J.E.1    Tipler, C.2    Laszlo, L.3    Hope, J.4    Landon, M.5    Mayer, R.J.6
  • 2
    • 0028840239 scopus 로고
    • Paired helical filament tau (PHFtau) in Niemann-Pick type C disease is similar to PHFtau in Alzheimer's disease
    • I.A. Auer, M.L. Schmidt, V.M. Lee, B. Curry, K. Suzuki, and R.W. Shin Paired helical filament tau (PHFtau) in Niemann-Pick type C disease is similar to PHFtau in Alzheimer's disease Acta Neuropathol (Berl) 90 1995 547 551
    • (1995) Acta Neuropathol (Berl) , vol.90 , pp. 547-551
    • Auer, I.A.1    Schmidt, M.L.2    Lee, V.M.3    Curry, B.4    Suzuki, K.5    Shin, R.W.6
  • 3
    • 0041488656 scopus 로고    scopus 로고
    • Hrs regulates multivesicular body formation via ESCRT recruitment to endosomes
    • K.G. Bache, A. Brech, A. Mehlum, and H. Stenmark Hrs regulates multivesicular body formation via ESCRT recruitment to endosomes J Cell Biol 162 2003 435 442
    • (2003) J Cell Biol , vol.162 , pp. 435-442
    • Bache, K.G.1    Brech, A.2    Mehlum, A.3    Stenmark, H.4
  • 4
    • 0348147670 scopus 로고    scopus 로고
    • Dynamics of endosomal sorting
    • N.E. Bishop Dynamics of endosomal sorting Int Rev Cytol 232 2003 1 57
    • (2003) Int Rev Cytol , vol.232 , pp. 1-57
    • Bishop, N.E.1
  • 5
    • 0026519231 scopus 로고
    • Antigen processing and presentation: Close encounters in the endocytic pathway
    • F.M. Brodsky Antigen processing and presentation: close encounters in the endocytic pathway Trends Cell Biol 2 1992 109 115
    • (1992) Trends Cell Biol , vol.2 , pp. 109-115
    • Brodsky, F.M.1
  • 6
    • 0036703779 scopus 로고    scopus 로고
    • Deregulation of cdk5, hyperphosphorylation, and cytoskeletal pathology in the Niemann-Pick type C murine model
    • B. Bu, J. Li, P. Davies, and I. Vincent Deregulation of cdk5, hyperphosphorylation, and cytoskeletal pathology in the Niemann-Pick type C murine model J Neurosci 22 2002 6515 6525
    • (2002) J Neurosci , vol.22 , pp. 6515-6525
    • Bu, B.1    Li, J.2    Davies, P.3    Vincent, I.4
  • 7
    • 0026744303 scopus 로고
    • The small GTPase rab5 functions as a regulatory factor in the early endocytic pathway
    • C. Bucci, R.G. Parton, I.H. Mather, H. Stunnenberg, K. Simons, and B. Hoflack The small GTPase rab5 functions as a regulatory factor in the early endocytic pathway Cell 70 1992 715 728
    • (1992) Cell , vol.70 , pp. 715-728
    • Bucci, C.1    Parton, R.G.2    Mather, I.H.3    Stunnenberg, H.4    Simons, K.5    Hoflack, B.6
  • 8
    • 0025614352 scopus 로고
    • Evidence for decreased transport of tryptophan hydroxylase in Alzheimer's disease
    • W.J. Burke, D.H. Park, H.D. Chung, G.L. Marshall, J.H. Haring, and T.H. Joh Evidence for decreased transport of tryptophan hydroxylase in Alzheimer's disease Brain Res 537 1990 83 87
    • (1990) Brain Res , vol.537 , pp. 83-87
    • Burke, W.J.1    Park, D.H.2    Chung, H.D.3    Marshall, G.L.4    Haring, J.H.5    Joh, T.H.6
  • 9
    • 0038045571 scopus 로고    scopus 로고
    • Presenilin redistribution associated with aberrant cholesterol transport enhances beta-amyloid production in vivo
    • M. Burns, K. Gaynor, V. Olm, M. Mercken, J. LaFrancois, and L. Wang Presenilin redistribution associated with aberrant cholesterol transport enhances beta-amyloid production in vivo J Neurosci 23 2003 5645 5649
    • (2003) J Neurosci , vol.23 , pp. 5645-5649
    • Burns, M.1    Gaynor, K.2    Olm, V.3    Mercken, M.4    Lafrancois, J.5    Wang, L.6
  • 10
    • 0031915887 scopus 로고    scopus 로고
    • Rabphilin-3A: A multifunctional regulator of synaptic vesicle traffic
    • M.E. Burns, T. Sasaki, Y. Takai, and G.J. Augustine Rabphilin-3A: a multifunctional regulator of synaptic vesicle traffic J Gen Physiol 111 1998 243 255
    • (1998) J Gen Physiol , vol.111 , pp. 243-255
    • Burns, M.E.1    Sasaki, T.2    Takai, Y.3    Augustine, G.J.4
  • 11
    • 14444272986 scopus 로고    scopus 로고
    • Evidence that tumor necrosis factor alpha converting enzyme is involved in regulated alpha-secretase cleavage of the Alzheimer amyloid protein precursor
    • J.D. Buxbaum, K.N. Liu, Y. Luo, J.L. Slack, K.L. Stocking, and J.J. Peschon Evidence that tumor necrosis factor alpha converting enzyme is involved in regulated alpha-secretase cleavage of the Alzheimer amyloid protein precursor J Biol Chem 273 1998 27765 27767
    • (1998) J Biol Chem , vol.273 , pp. 27765-27767
    • Buxbaum, J.D.1    Liu, K.N.2    Luo, Y.3    Slack, J.L.4    Stocking, K.L.5    Peschon, J.J.6
  • 12
    • 0033783140 scopus 로고    scopus 로고
    • Presenilin-1 differentially facilitates endoproteolysis of the beta-amyloid precursor protein and Notch
    • A. Capell, H. Steiner, H. Romig, S. Keck, M. Baader, and M.G. Grim Presenilin-1 differentially facilitates endoproteolysis of the beta-amyloid precursor protein and Notch Nat Cell Biol 2 2000 205 211
    • (2000) Nat Cell Biol , vol.2 , pp. 205-211
    • Capell, A.1    Steiner, H.2    Romig, H.3    Keck, S.4    Baader, M.5    Grim, M.G.6
  • 13
  • 14
    • 0030836345 scopus 로고    scopus 로고
    • Increased neuronal endocytosis and protease delivery to early endosomes in sporadic Alzheimer's disease: Neuropathologic evidence for a mechanism of increased beta-amyloidogenesis
    • A.M. Cataldo, J.L. Barnett, C. Pieroni, and R.A. Nixon Increased neuronal endocytosis and protease delivery to early endosomes in sporadic Alzheimer's disease: neuropathologic evidence for a mechanism of increased beta-amyloidogenesis J Neurosci 17 1997 6142 6151
    • (1997) J Neurosci , vol.17 , pp. 6142-6151
    • Cataldo, A.M.1    Barnett, J.L.2    Pieroni, C.3    Nixon, R.A.4
  • 15
    • 0041632362 scopus 로고    scopus 로고
    • App gene dosage modulates endosomal abnormalities of Alzheimer's disease in a segmental trisomy 16 mouse model of Down syndrome
    • A.M. Cataldo, S. Petanceska, C.M. Peterhoff, N.B. Terio, C.J. Epstein, and A. Villar App gene dosage modulates endosomal abnormalities of Alzheimer's disease in a segmental trisomy 16 mouse model of Down syndrome J Neurosci 23 2003 6788 6792
    • (2003) J Neurosci , vol.23 , pp. 6788-6792
    • Cataldo, A.M.1    Petanceska, S.2    Peterhoff, C.M.3    Terio, N.B.4    Epstein, C.J.5    Villar, A.6
  • 16
    • 4644319713 scopus 로고    scopus 로고
    • Aβ localization in abnormal endosomes: Association with earliest Aβ elevations in AD and Down Syndrome
    • A.M. Cataldo, S. Petanceska, N.B. Terio, C.M. Peterhoff, R. Durham, and M. Mercken Aβ localization in abnormal endosomes: association with earliest Aβ elevations in AD and Down Syndrome Neurobiol Aging 25 2004 1263 1272
    • (2004) Neurobiol Aging , vol.25 , pp. 1263-1272
    • Cataldo, A.M.1    Petanceska, S.2    Terio, N.B.3    Peterhoff, C.M.4    Durham, R.5    Mercken, M.6
  • 17
    • 0033869715 scopus 로고    scopus 로고
    • Endocytic pathway abnormalities precede amyloid beta deposition in sporadic Alzheimer's disease and Down syndrome: Differential effects of APOE genotype and presenilin mutations
    • A.M. Cataldo, C.M. Peterhoff, J.C. Troncoso, T. Gomez-Isla, B.T. Hyman, and R.A. Nixon Endocytic pathway abnormalities precede amyloid beta deposition in sporadic Alzheimer's disease and Down syndrome: differential effects of APOE genotype and presenilin mutations Am J Pathol 157 2000 277 286
    • (2000) Am J Pathol , vol.157 , pp. 277-286
    • Cataldo, A.M.1    Peterhoff, C.M.2    Troncoso, J.C.3    Gomez-Isla, T.4    Hyman, B.T.5    Nixon, R.A.6
  • 18
    • 0037047287 scopus 로고    scopus 로고
    • (ALG-2-interacting protein X), a protein involved in apoptosis, binds to endophilins and induces cytoplasmic vacuolization
    • C. Chatellard-Causse, B. Blot, N. Cristina, S. Torch, M. Missotten, and R. Sadoul (ALG-2-interacting protein X), a protein involved in apoptosis, binds to endophilins and induces cytoplasmic vacuolization J Biol Chem 277 2002 29108 29115
    • (2002) J Biol Chem , vol.277 , pp. 29108-29115
    • Chatellard-Causse, C.1    Blot, B.2    Cristina, N.3    Torch, S.4    Missotten, M.5    Sadoul, R.6
  • 19
    • 0034705484 scopus 로고    scopus 로고
    • The glioma-associated protein SETA interacts with AIP1/Alix and ALG-2 and modulates apoptosis in astrocytes
    • B. Chen, S.C. Borinstein, J. Gillis, V.W. Sykes, and O. Bogler The glioma-associated protein SETA interacts with AIP1/Alix and ALG-2 and modulates apoptosis in astrocytes J Biol Chem 275 2000 19275 19281
    • (2000) J Biol Chem , vol.275 , pp. 19275-19281
    • Chen, B.1    Borinstein, S.C.2    Gillis, J.3    Sykes, V.W.4    Bogler, O.5
  • 20
    • 3442876436 scopus 로고    scopus 로고
    • Posttranslational modifications of tau-role in human tauopathies and modeling in transgenic animals
    • F. Chen, D. David, A. Ferrari, and J. Gotz Posttranslational modifications of tau-role in human tauopathies and modeling in transgenic animals Curr Drug Targets 5 2004 503 515
    • (2004) Curr Drug Targets , vol.5 , pp. 503-515
    • Chen, F.1    David, D.2    Ferrari, A.3    Gotz, J.4
  • 21
    • 2942591228 scopus 로고    scopus 로고
    • Failed retrograde transport of NGF in a mouse model of Down's syndrome: Reversal of cholinergic neurodegenerative phenotypes following NGF infusion
    • J.D. Cooper, A. Salehi, J.D. Delcroix, C.L. Howe, P.V. Belichenko, and J. Chua-Couzens Failed retrograde transport of NGF in a mouse model of Down's syndrome: reversal of cholinergic neurodegenerative phenotypes following NGF infusion Proc Natl Acad Sci USA 98 2001 10439 10444
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 10439-10444
    • Cooper, J.D.1    Salehi, A.2    Delcroix, J.D.3    Howe, C.L.4    Belichenko, P.V.5    Chua-Couzens, J.6
  • 22
    • 0030886261 scopus 로고    scopus 로고
    • The AP-3 adaptor complex is essential for cargo-selective transport to the yeast vacuole
    • C.R. Cowles, G. Odorizzi, G.S. Payne, and S.D. Emr The AP-3 adaptor complex is essential for cargo-selective transport to the yeast vacuole Cell 91 1997 109 118
    • (1997) Cell , vol.91 , pp. 109-118
    • Cowles, C.R.1    Odorizzi, G.2    Payne, G.S.3    Emr, S.D.4
  • 23
    • 0035921427 scopus 로고    scopus 로고
    • The discrepancy between presenilin subcellular localization and gamma-secretase processing of amyloid precursor protein
    • P. Cupers, M. Bentahir, K. Craessaerts, I. Orlans, H. Vanderstichele, and P. Saftig The discrepancy between presenilin subcellular localization and gamma-secretase processing of amyloid precursor protein J Cell Biol 154 2001 731 740
    • (2001) J Cell Biol , vol.154 , pp. 731-740
    • Cupers, P.1    Bentahir, M.2    Craessaerts, K.3    Orlans, I.4    Vanderstichele, H.5    Saftig, P.6
  • 25
    • 0033623888 scopus 로고    scopus 로고
    • APOE epsilon 4 influences the manifestation of Alzheimer's disease in adults with Down's syndrome
    • S. Deb, J. Braganza, N. Norton, H. Williams, P.G. Kehoe, and J. Williams APOE epsilon 4 influences the manifestation of Alzheimer's disease in adults with Down's syndrome Br J Psychiat 176 2000 468 472
    • (2000) Br J Psychiat , vol.176 , pp. 468-472
    • Deb, S.1    Braganza, J.2    Norton, N.3    Williams, H.4    Kehoe, P.G.5    Williams, J.6
  • 26
    • 0037899137 scopus 로고    scopus 로고
    • NGF signaling in sensory neurons: Evidence that early endosomes carry NGF retrograde signals
    • J.D. Delcroix, J.S. Valletta, C. Wu, S.J. Hunt, A.S. Kowal, and W.C. Mobley NGF signaling in sensory neurons: evidence that early endosomes carry NGF retrograde signals Neuron 39 2003 69 84
    • (2003) Neuron , vol.39 , pp. 69-84
    • Delcroix, J.D.1    Valletta, J.S.2    Wu, C.3    Hunt, S.J.4    Kowal, A.S.5    Mobley, W.C.6
  • 27
    • 0030752709 scopus 로고    scopus 로고
    • Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain
    • M. DiFiglia, E. Sapp, K.O. Chase, S.W. Davies, G.P. Bates, and J.P. Vonsattel Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain Science 277 1997 1990 1993
    • (1997) Science , vol.277 , pp. 1990-1993
    • Difiglia, M.1    Sapp, E.2    Chase, K.O.3    Davies, S.W.4    Bates, G.P.5    Vonsattel, J.P.6
  • 29
    • 0042025826 scopus 로고    scopus 로고
    • Understanding mental retardation in Down's syndrome using trisomy 16 mouse models
    • Z. Galdzicki, and R.J. Siarey Understanding mental retardation in Down's syndrome using trisomy 16 mouse models Genes Brain Behav 2 2003 167 178
    • (2003) Genes Brain Behav , vol.2 , pp. 167-178
    • Galdzicki, Z.1    Siarey, R.J.2
  • 30
    • 0035821438 scopus 로고    scopus 로고
    • Selective neurodegeneration, without neurofibrillary tangles, in a mouse model of Niemann-Pick C disease
    • D.C. German, E.M. Quintero, C.L. Liang, B. Ng, S. Punia, and C. Xie Selective neurodegeneration, without neurofibrillary tangles, in a mouse model of Niemann-Pick C disease J Comp Neurol 433 2001 415 425
    • (2001) J Comp Neurol , vol.433 , pp. 415-425
    • German, D.C.1    Quintero, E.M.2    Liang, C.L.3    Ng, B.4    Punia, S.5    Xie, C.6
  • 31
    • 0036173770 scopus 로고    scopus 로고
    • Recruitment and activation of caspase-8 by the Huntingtin-interacting protein Hip-1 and a novel partner Hippi
    • F.G. Gervais, R. Singaraja, S. Xanthoudakis, C.A. Gutekunst, B.R. Leavitt, and M. Metzler Recruitment and activation of caspase-8 by the Huntingtin-interacting protein Hip-1 and a novel partner Hippi Nat Cell Biol 4 2002 95 105
    • (2002) Nat Cell Biol , vol.4 , pp. 95-105
    • Gervais, F.G.1    Singaraja, R.2    Xanthoudakis, S.3    Gutekunst, C.A.4    Leavitt, B.R.5    Metzler, M.6
  • 32
    • 0037336348 scopus 로고    scopus 로고
    • Mannose 6-phosphate receptors: New twists in the tale
    • P. Ghosh, N.M. Dahms, and S. Kornfeld Mannose 6-phosphate receptors: new twists in the tale Nat Rev Mol Cell Biol 4 2003 202 212
    • (2003) Nat Rev Mol Cell Biol , vol.4 , pp. 202-212
    • Ghosh, P.1    Dahms, N.M.2    Kornfeld, S.3
  • 33
    • 1242316987 scopus 로고    scopus 로고
    • H2O2-dependent activation of GCLC-ARE4 reporter occurs by mitogen-activated protein kinase pathways without oxidation of cellular glutathione or thioredoxin-1
    • Y.M. Go, J.J. Gipp, R.T. Mulcahy, and D.P. Jones H2O2-dependent activation of GCLC-ARE4 reporter occurs by mitogen-activated protein kinase pathways without oxidation of cellular glutathione or thioredoxin-1 J Biol Chem 279 2004 5837 5845
    • (2004) J Biol Chem , vol.279 , pp. 5837-5845
    • Go, Y.M.1    Gipp, J.J.2    Mulcahy, R.T.3    Jones, D.P.4
  • 34
    • 0035896491 scopus 로고    scopus 로고
    • Transduction. When worlds collide - Trafficking in JNK
    • L.S. Goldstein Transduction. When worlds collide - trafficking in JNK Science 291 2001 2102 2103
    • (2001) Science , vol.291 , pp. 2102-2103
    • Goldstein, L.S.1
  • 35
    • 0025974686 scopus 로고
    • Rab5 controls early endosome fusion in vitro
    • J.P. Gorvel, P. Chavrier, M. Zerial, and J. Gruenberg rab5 controls early endosome fusion in vitro Cell 64 1991 915 925
    • (1991) Cell , vol.64 , pp. 915-925
    • Gorvel, J.P.1    Chavrier, P.2    Zerial, M.3    Gruenberg, J.4
  • 37
    • 0042733013 scopus 로고    scopus 로고
    • Rab5-stimulated up-regulation of the endocytic pathway increases intracellular beta-cleaved amyloid precursor protein carboxyl-terminal fragment levels and Abeta production
    • O.M. Grbovic, P.M. Mathews, Y. Jiang, S.D. Schmidt, R. Dinakar, and N.B. Summers-Terio Rab5-stimulated up-regulation of the endocytic pathway increases intracellular beta-cleaved amyloid precursor protein carboxyl-terminal fragment levels and Abeta production J Biol Chem 278 2003 31261 31268
    • (2003) J Biol Chem , vol.278 , pp. 31261-31268
    • Grbovic, O.M.1    Mathews, P.M.2    Jiang, Y.3    Schmidt, S.D.4    Dinakar, R.5    Summers-Terio, N.B.6
  • 38
    • 0025817708 scopus 로고
    • The arguments for pre-existing early and late endosomes
    • G. Griffiths, and J. Gruenberg The arguments for pre-existing early and late endosomes Trends Cell Biol 1 1991 5 9
    • (1991) Trends Cell Biol , vol.1 , pp. 5-9
    • Griffiths, G.1    Gruenberg, J.2
  • 39
    • 0033558032 scopus 로고    scopus 로고
    • The sec6/8 complex is located at neurite outgrowth and axonal synapse-assembly domains
    • C.D. Hazuka, D.L. Foletti, S.C. Hsu, Y. Kee, F.W. Hopf, and R.H. Scheller The sec6/8 complex is located at neurite outgrowth and axonal synapse-assembly domains J Neurosci 19 1999 1324 1334
    • (1999) J Neurosci , vol.19 , pp. 1324-1334
    • Hazuka, C.D.1    Foletti, D.L.2    Hsu, S.C.3    Kee, Y.4    Hopf, F.W.5    Scheller, R.H.6
  • 40
    • 0027419879 scopus 로고
    • Products of endocytosis and autophagy are retrieved from axons by regulated retrograde organelle transport
    • P.J. Hollenbeck Products of endocytosis and autophagy are retrieved from axons by regulated retrograde organelle transport J Cell Biol 121 1993 305 315
    • (1993) J Cell Biol , vol.121 , pp. 305-315
    • Hollenbeck, P.J.1
  • 42
    • 0035819073 scopus 로고    scopus 로고
    • NGF signaling from clathrin-coated vesicles: Evidence that signaling endosomes serve as a platform for the Ras-MAPK pathway
    • C.L. Howe, J.S. Valletta, A.S. Rusnak, and W.C. Mobley NGF signaling from clathrin-coated vesicles: evidence that signaling endosomes serve as a platform for the Ras-MAPK pathway Neuron 32 2001 801 814
    • (2001) Neuron , vol.32 , pp. 801-814
    • Howe, C.L.1    Valletta, J.S.2    Rusnak, A.S.3    Mobley, W.C.4
  • 43
    • 0028962046 scopus 로고
    • Neuropathological changes in Down's syndrome hippocampal formation. Effect of age and apolipoprotein e genotype
    • B.T. Hyman, H.L. West, G.W. Rebeck, F. Lai, and D.M. Mann Neuropathological changes in Down's syndrome hippocampal formation. Effect of age and apolipoprotein E genotype Arch Neurol 52 1995 373 378
    • (1995) Arch Neurol , vol.52 , pp. 373-378
    • Hyman, B.T.1    West, H.L.2    Rebeck, G.W.3    Lai, F.4    Mann, D.M.5
  • 44
    • 1242316263 scopus 로고    scopus 로고
    • Intracellular accumulation of amyloidogenic fragments of amyloid-beta precursor protein in neurons with Niemann-Pick type C defects is associated with endosomal abnormalities
    • L.W. Jin, I. Maezawa, I. Vincent, and T. Bird Intracellular accumulation of amyloidogenic fragments of amyloid-beta precursor protein in neurons with Niemann-Pick type C defects is associated with endosomal abnormalities Am J Pathol 164 2004 975 985
    • (2004) Am J Pathol , vol.164 , pp. 975-985
    • Jin, L.W.1    Maezawa, I.2    Vincent, I.3    Bird, T.4
  • 45
    • 0035818998 scopus 로고    scopus 로고
    • Kinesin-mediated axonal transport of a membrane compartment containing beta-secretase and presenilin-1 requires APP
    • A. Kamal, A. Almenar-Queralt, J.F. LeBlanc, E.A. Roberts, and L.S. Goldstein Kinesin-mediated axonal transport of a membrane compartment containing beta-secretase and presenilin-1 requires APP Nature 414 2001 643 648
    • (2001) Nature , vol.414 , pp. 643-648
    • Kamal, A.1    Almenar-Queralt, A.2    Leblanc, J.F.3    Roberts, E.A.4    Goldstein, L.S.5
  • 46
    • 0033636136 scopus 로고    scopus 로고
    • Axonal transport of amyloid precursor protein is mediated by direct binding to the kinesin light chain subunit of kinesin-I
    • A. Kamal, G.B. Stokin, Z. Yang, C.H. Xia, and L.S. Goldstein Axonal transport of amyloid precursor protein is mediated by direct binding to the kinesin light chain subunit of kinesin-I Neuron 28 2000 449 459
    • (2000) Neuron , vol.28 , pp. 449-459
    • Kamal, A.1    Stokin, G.B.2    Yang, Z.3    Xia, C.H.4    Goldstein, L.S.5
  • 47
    • 0037423184 scopus 로고    scopus 로고
    • Trafficking of cholesterol from cell bodies to distal axons in Niemann Pick C1-deficient neurons
    • B. Karten, D.E. Vance, R.B. Campenot, and J.E. Vance Trafficking of cholesterol from cell bodies to distal axons in Niemann Pick C1-deficient neurons J Biol Chem 278 2003 4168 4175
    • (2003) J Biol Chem , vol.278 , pp. 4168-4175
    • Karten, B.1    Vance, D.E.2    Campenot, R.B.3    Vance, J.E.4
  • 48
    • 0141643096 scopus 로고    scopus 로고
    • The ALG-2-interacting protein Alix associates with CHMP4b, a human homologue of yeast Snf7 that is involved in multivesicular body sorting
    • K. Katoh, H. Shibata, H. Suzuki, A. Nara, K. Ishidoh, and E. Kominami The ALG-2-interacting protein Alix associates with CHMP4b, a human homologue of yeast Snf7 that is involved in multivesicular body sorting J Biol Chem 278 2003 39104 39113
    • (2003) J Biol Chem , vol.278 , pp. 39104-39113
    • Katoh, K.1    Shibata, H.2    Suzuki, H.3    Nara, A.4    Ishidoh, K.5    Kominami, E.6
  • 49
    • 0035958546 scopus 로고    scopus 로고
    • Ubiquitin-dependent sorting into the multivesicular body pathway requires the function of a conserved endosomal protein sorting complex, ESCRT-I
    • D.J. Katzmann, M. Babst, and S.D. Emr Ubiquitin-dependent sorting into the multivesicular body pathway requires the function of a conserved endosomal protein sorting complex, ESCRT-I Cell 106 2001 145 155
    • (2001) Cell , vol.106 , pp. 145-155
    • Katzmann, D.J.1    Babst, M.2    Emr, S.D.3
  • 50
    • 0036902646 scopus 로고    scopus 로고
    • Receptor downregulation and multivesicular-body sorting
    • D.J. Katzmann, G. Odorizzi, and S.D. Emr Receptor downregulation and multivesicular-body sorting Nat Rev Mol Cell Biol 3 2002 893 905
    • (2002) Nat Rev Mol Cell Biol , vol.3 , pp. 893-905
    • Katzmann, D.J.1    Odorizzi, G.2    Emr, S.D.3
  • 51
    • 0242668337 scopus 로고    scopus 로고
    • Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis
    • R. Kayed, E. Head, J.L. Thompson, T.M. McIntire, S.C. Milton, and C.W. Cotman Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis Science 300 2003 486 489
    • (2003) Science , vol.300 , pp. 486-489
    • Kayed, R.1    Head, E.2    Thompson, J.L.3    McIntire, T.M.4    Milton, S.C.5    Cotman, C.W.6
  • 52
    • 0034307476 scopus 로고    scopus 로고
    • Huntingtin expression stimulates endosomal-lysosomal activity, endosome tubulation, and autophagy
    • K.B. Kegel, M. Kim, E. Sapp, C. McIntyre, J.G. Castano, and N. Aronin Huntingtin expression stimulates endosomal-lysosomal activity, endosome tubulation, and autophagy J Neurosci 20 2000 7268 7278
    • (2000) J Neurosci , vol.20 , pp. 7268-7278
    • Kegel, K.B.1    Kim, M.2    Sapp, E.3    McIntyre, C.4    Castano, J.G.5    Aronin, N.6
  • 53
    • 0036536713 scopus 로고    scopus 로고
    • MAP kinase cascade signaling and endocytic trafficking: A marriage of convenience?
    • B.N. Kholodenko MAP kinase cascade signaling and endocytic trafficking: a marriage of convenience? Trends Cell Biol 12 2002 173 177
    • (2002) Trends Cell Biol , vol.12 , pp. 173-177
    • Kholodenko, B.N.1
  • 55
    • 0028276801 scopus 로고
    • Evidence that production and release of amyloid beta-protein involves the endocytic pathway
    • E.H. Koo, and S.L. Squazzo Evidence that production and release of amyloid beta-protein involves the endocytic pathway J Biol Chem 269 1994 17386 17389
    • (1994) J Biol Chem , vol.269 , pp. 17386-17389
    • Koo, E.H.1    Squazzo, S.L.2
  • 56
    • 0032077286 scopus 로고    scopus 로고
    • Two distinct pools of synaptic vesicles in single presynaptic boutons in a temperature-sensitive Drosophila mutant, shibire
    • H. Kuromi, and Y. Kidokoro Two distinct pools of synaptic vesicles in single presynaptic boutons in a temperature-sensitive Drosophila mutant, shibire Neuron 20 1998 917 925
    • (1998) Neuron , vol.20 , pp. 917-925
    • Kuromi, H.1    Kidokoro, Y.2
  • 57
    • 0033595202 scopus 로고    scopus 로고
    • APOE genotype and gender effects on Alzheimer disease in 100 adults with Down syndrome
    • F. Lai, E. Kammann, G.W. Rebeck, A. Anderson, Y. Chen, and R.A. Nixon APOE genotype and gender effects on Alzheimer disease in 100 adults with Down syndrome Neurology 53 1999 331 336
    • (1999) Neurology , vol.53 , pp. 331-336
    • Lai, F.1    Kammann, E.2    Rebeck, G.W.3    Anderson, A.4    Chen, Y.5    Nixon, R.A.6
  • 58
    • 0024370171 scopus 로고
    • A prospective study of Alzheimer disease in Down syndrome
    • F. Lai, and R.S. Williams A prospective study of Alzheimer disease in Down syndrome Arch Neurol 46 1989 849 853
    • (1989) Arch Neurol , vol.46 , pp. 849-853
    • Lai, F.1    Williams, R.S.2
  • 59
    • 0016282331 scopus 로고
    • The retrograde intraaxonal transport of horseradish peroxidase in the chick visual system: A light and electron microscopic study
    • J.H. LaVail, and M.M. LaVail The retrograde intraaxonal transport of horseradish peroxidase in the chick visual system: a light and electron microscopic study J Comp Neurol 157 1974 303 357
    • (1974) J Comp Neurol , vol.157 , pp. 303-357
    • Lavail, J.H.1    Lavail, M.M.2
  • 60
    • 1842583789 scopus 로고    scopus 로고
    • Development by self-digestion; Molecular mechanisms and biological functions of autophagy
    • B. Levine, and D.J. Klionsky Development by self-digestion; molecular mechanisms and biological functions of autophagy Dev Cell 6 2004 463 477
    • (2004) Dev Cell , vol.6 , pp. 463-477
    • Levine, B.1    Klionsky, D.J.2
  • 61
    • 0037169336 scopus 로고    scopus 로고
    • Hrs regulates endosome membrane invagination and tyrosine kinase receptor signaling in Drosophila
    • T.E. Lloyd, R. Atkinson, M.N. Wu, Y. Zhou, G. Pennetta, and H.J. Bellen Hrs regulates endosome membrane invagination and tyrosine kinase receptor signaling in Drosophila Cell 108 2002 261 269
    • (2002) Cell , vol.108 , pp. 261-269
    • Lloyd, T.E.1    Atkinson, R.2    Wu, M.N.3    Zhou, Y.4    Pennetta, G.5    Bellen, H.J.6
  • 62
    • 0035089318 scopus 로고    scopus 로고
    • Constitutive alpha-secretase cleavage of the beta-amyloid precursor protein in the furin-deficient LoVo cell line: Involvement of the pro-hormone convertase 7 and the disintegrin metalloprotease ADAM10
    • E. Lopez-Perez, Y. Zhang, S.J. Frank, J. Creemers, N. Seidah, and F. Checler Constitutive alpha-secretase cleavage of the beta-amyloid precursor protein in the furin-deficient LoVo cell line: involvement of the pro-hormone convertase 7 and the disintegrin metalloprotease ADAM10 J Neurochem 76 2001 1532 1539
    • (2001) J Neurochem , vol.76 , pp. 1532-1539
    • Lopez-Perez, E.1    Zhang, Y.2    Frank, S.J.3    Creemers, J.4    Seidah, N.5    Checler, F.6
  • 63
    • 0028929548 scopus 로고
    • Neurofibrillary tangles in Niemann-Pick disease type C
    • S. Love, L.R. Bridges, and C.P. Case Neurofibrillary tangles in Niemann-Pick disease type C Brain 118 Pt 1 1995 119 129
    • (1995) Brain , vol.118 , Issue.1 , pp. 119-129
    • Love, S.1    Bridges, L.R.2    Case, C.P.3
  • 64
    • 0032888131 scopus 로고    scopus 로고
    • Soluble amyloid beta peptide concentration as a predictor of synaptic change in Alzheimer's disease
    • L.F. Lue, Y.M. Kuo, A.E. Roher, L. Brachova, Y. Shen, and L. Sue Soluble amyloid beta peptide concentration as a predictor of synaptic change in Alzheimer's disease Am J Pathol 155 1999 853 862
    • (1999) Am J Pathol , vol.155 , pp. 853-862
    • Lue, L.F.1    Kuo, Y.M.2    Roher, A.E.3    Brachova, L.4    Shen, Y.5    Sue, L.6
  • 65
    • 2542432265 scopus 로고    scopus 로고
    • The structure of the MAPK scaffold, MP1, bound to its partner, p14. A complex with a critical role in endosomal map kinase signalling
    • V.V. Lunin, C. Munger, J. Wagner, Z. Ye, M. Cygler, and M. Sacher The structure of the MAPK scaffold, MP1, bound to its partner, p14. A complex with a critical role in endosomal map kinase signalling J Biol Chem 279 2004 23422 23430
    • (2004) J Biol Chem , vol.279 , pp. 23422-23430
    • Lunin, V.V.1    Munger, C.2    Wagner, J.3    Ye, Z.4    Cygler, M.5    Sacher, M.6
  • 67
    • 0032851639 scopus 로고    scopus 로고
    • Endocytic vacuoles formed following a short pulse of K+-stimulation contain a plethora of presynaptic membrane proteins
    • M. Marxen, W. Volknandt, and H. Zimmermann Endocytic vacuoles formed following a short pulse of K+-stimulation contain a plethora of presynaptic membrane proteins Neuroscience 94 1999 985 996
    • (1999) Neuroscience , vol.94 , pp. 985-996
    • Marxen, M.1    Volknandt, W.2    Zimmermann, H.3
  • 68
    • 0037085458 scopus 로고    scopus 로고
    • Alzheimer's disease-related overexpression of the cation-dependent mannose 6-phosphate receptor increases Abeta secretion: Role for altered lysosomal hydrolase distribution in beta-amyloidogenesis
    • P.M. Mathews, C.B. Guerra, Y. Jiang, O.M. Grbovic, B.H. Kao, and S.D. Schmidt Alzheimer's disease-related overexpression of the cation-dependent mannose 6-phosphate receptor increases Abeta secretion: role for altered lysosomal hydrolase distribution in beta-amyloidogenesis J Biol Chem 277 2002 5299 5307
    • (2002) J Biol Chem , vol.277 , pp. 5299-5307
    • Mathews, P.M.1    Guerra, C.B.2    Jiang, Y.3    Grbovic, O.M.4    Kao, B.H.5    Schmidt, S.D.6
  • 69
    • 0037184127 scopus 로고    scopus 로고
    • Calpain activity regulates the cell surface distribution of amyloid precursor protein. Inhibition of calpains enhances endosomal generation of β-cleaved C-terminal APP fragments
    • P.M. Mathews, Y. Jiang, S.D. Schmidt, O.M. Grbovic, M. Mercken, and R.A. Nixon Calpain activity regulates the cell surface distribution of amyloid precursor protein. Inhibition of calpains enhances endosomal generation of β-cleaved C-terminal APP fragments J Biol. Chem. 277 2002 36415 36424
    • (2002) J Biol. Chem. , vol.277 , pp. 36415-36424
    • Mathews, P.M.1    Jiang, Y.2    Schmidt, S.D.3    Grbovic, O.M.4    Mercken, M.5    Nixon, R.A.6
  • 70
    • 0032590054 scopus 로고    scopus 로고
    • Soluble pool of Abeta amyloid as a determinant of severity of neurodegeneration in Alzheimer's disease
    • C.A. McLean, R.A. Cherny, F.W. Fraser, S.J. Fuller, M.J. Smith, and K. Beyreuther Soluble pool of Abeta amyloid as a determinant of severity of neurodegeneration in Alzheimer's disease Ann Neurol 46 1999 860 866
    • (1999) Ann Neurol , vol.46 , pp. 860-866
    • McLean, C.A.1    Cherny, R.A.2    Fraser, F.W.3    Fuller, S.J.4    Smith, M.J.5    Beyreuther, K.6
  • 71
    • 0038771182 scopus 로고    scopus 로고
    • RIPped out by presenilin-dependent gamma-secretase
    • M. Medina, and C.G. Dotti RIPped out by presenilin-dependent gamma-secretase Cell Signal 15 2003 829 841
    • (2003) Cell Signal , vol.15 , pp. 829-841
    • Medina, M.1    Dotti, C.G.2
  • 72
    • 0037926396 scopus 로고    scopus 로고
    • Disruption of the endocytic protein HIP1 results in neurological deficits and decreased AMPA receptor trafficking
    • M. Metzler, B. Li, L. Gan, J. Georgiou, C.A. Gutekunst, and Y. Wang Disruption of the endocytic protein HIP1 results in neurological deficits and decreased AMPA receptor trafficking Embo J 22 2003 3254 3266
    • (2003) Embo J , vol.22 , pp. 3254-3266
    • Metzler, M.1    Li, B.2    Gan, L.3    Georgiou, J.4    Gutekunst, C.A.5    Wang, Y.6
  • 73
    • 0033043513 scopus 로고    scopus 로고
    • Alix, a novel mouse protein undergoing calcium-dependent interaction with the apoptosis-linked-gene 2 (ALG-2) protein
    • M. Missotten, A. Nichols, K. Rieger, and R. Sadoul Alix, a novel mouse protein undergoing calcium-dependent interaction with the apoptosis-linked-gene 2 (ALG-2) protein Cell Death Differ 6 1999 124 129
    • (1999) Cell Death Differ , vol.6 , pp. 124-129
    • Missotten, M.1    Nichols, A.2    Rieger, K.3    Sadoul, R.4
  • 74
    • 0029942903 scopus 로고    scopus 로고
    • Origin of cholesterol in myelin
    • P. Morell, and H. Jurevics Origin of cholesterol in myelin Neurochem Res 21 1996 463 470
    • (1996) Neurochem Res , vol.21 , pp. 463-470
    • Morell, P.1    Jurevics, H.2
  • 75
    • 0025808286 scopus 로고
    • Maturation models for endosome and lysosome biogenesis
    • R.F. Murphy Maturation models for endosome and lysosome biogenesis Trends Cell Biol 1 1991 77 82
    • (1991) Trends Cell Biol , vol.1 , pp. 77-82
    • Murphy, R.F.1
  • 76
    • 0032473998 scopus 로고    scopus 로고
    • Synaptic vesicles retain their identity through the endocytic cycle
    • V.N. Murthy, and C.F. Stevens Synaptic vesicles retain their identity through the endocytic cycle Nature 392 1998 497 501
    • (1998) Nature , vol.392 , pp. 497-501
    • Murthy, V.N.1    Stevens, C.F.2
  • 77
    • 0037489514 scopus 로고    scopus 로고
    • Single-nucleotide polymorphisms in uncoding regions of ALS2 gene of Japanese patients with autosomal-recessive amyotrophic lateral sclerosis
    • I. Nagano, T. Murakami, M. Shiote, Y. Manabe, S. Hadano, and Y. Yanagisawa Single-nucleotide polymorphisms in uncoding regions of ALS2 gene of Japanese patients with autosomal-recessive amyotrophic lateral sclerosis Neurol Res 25 2003 505 509
    • (2003) Neurol Res , vol.25 , pp. 505-509
    • Nagano, I.1    Murakami, T.2    Shiote, M.3    Manabe, Y.4    Hadano, S.5    Yanagisawa, Y.6
  • 79
    • 1242316279 scopus 로고    scopus 로고
    • Niemann-Pick Type C disease and Alzheimer's disease: The APP-endosome connection fattens up
    • R.A. Nixon Niemann-Pick Type C disease and Alzheimer's disease: the APP-endosome connection fattens up Am J Pathol 164 2004 757 761
    • (2004) Am J Pathol , vol.164 , pp. 757-761
    • Nixon, R.A.1
  • 80
    • 0032479439 scopus 로고    scopus 로고
    • Topology of SREBP cleavage-activating protein, a polytopic membrane protein with a sterol-sensing domain
    • A. Nohturfft, M.S. Brown, and J.L. Goldstein Topology of SREBP cleavage-activating protein, a polytopic membrane protein with a sterol-sensing domain J Biol Chem 273 1998 17243 17250
    • (1998) J Biol Chem , vol.273 , pp. 17243-17250
    • Nohturfft, A.1    Brown, M.S.2    Goldstein, J.L.3
  • 81
    • 0037451783 scopus 로고    scopus 로고
    • Autophagy: A barrier or an adaptive response to cancer
    • E. Ogier-Denis, and P. Codogno Autophagy: a barrier or an adaptive response to cancer Biochim Biophys Acta 1603 2003 113 128
    • (2003) Biochim Biophys Acta , vol.1603 , pp. 113-128
    • Ogier-Denis, E.1    Codogno, P.2
  • 83
    • 0035031938 scopus 로고    scopus 로고
    • Re-localization of activated EGF receptor and its signal transducers to multivesicular compartments downstream of early endosomes in response to EGF
    • M.P. Oksvold, E. Skarpen, L. Wierod, R.E. Paulsen, and H.S. Huitfeldt Re-localization of activated EGF receptor and its signal transducers to multivesicular compartments downstream of early endosomes in response to EGF Eur J Cell Biol 80 2001 285 294
    • (2001) Eur J Cell Biol , vol.80 , pp. 285-294
    • Oksvold, M.P.1    Skarpen, E.2    Wierod, L.3    Paulsen, R.E.4    Huitfeldt, H.S.5
  • 84
    • 0041308082 scopus 로고    scopus 로고
    • ALS2, a novel guanine nucleotide exchange factor for the small GTPase Rab5, is implicated in endosomal dynamics
    • A. Otomo, S. Hadano, T. Okada, H. Mizumura, R. Kunita, and H. Nishijima ALS2, a novel guanine nucleotide exchange factor for the small GTPase Rab5, is implicated in endosomal dynamics Hum Mol Genet 12 2003 1671 1687
    • (2003) Hum Mol Genet , vol.12 , pp. 1671-1687
    • Otomo, A.1    Hadano, S.2    Okada, T.3    Mizumura, H.4    Kunita, R.5    Nishijima, H.6
  • 85
    • 0029813779 scopus 로고    scopus 로고
    • Dynamic organization of endocytic pathways in axons of cultured sympathetic neurons
    • C.C. Overly, and P.J. Hollenbeck Dynamic organization of endocytic pathways in axons of cultured sympathetic neurons J Neurosci 16 1996 6056 6064
    • (1996) J Neurosci , vol.16 , pp. 6056-6064
    • Overly, C.C.1    Hollenbeck, P.J.2
  • 86
    • 0028906375 scopus 로고
    • Quantitative measurement of intraorganelle pH in the endosomal-lysosomal pathway in neurons by using ratiometric imaging with pyranine
    • C.C. Overly, K.D. Lee, E. Berthiaume, and P.J. Hollenbeck Quantitative measurement of intraorganelle pH in the endosomal-lysosomal pathway in neurons by using ratiometric imaging with pyranine Proc Natl Acad Sci USA 92 1995 3156 3160
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 3156-3160
    • Overly, C.C.1    Lee, K.D.2    Berthiaume, E.3    Hollenbeck, P.J.4
  • 87
    • 0029948582 scopus 로고    scopus 로고
    • Organelle motility and metabolism in axons vs dendrites of cultured hippocampal neurons
    • C.C. Overly, H.I. Rieff, and P.J. Hollenbeck Organelle motility and metabolism in axons vs dendrites of cultured hippocampal neurons J Cell Sci 109 Pt 5 1996 971 980
    • (1996) J Cell Sci , vol.109 , Issue.5 , pp. 971-980
    • Overly, C.C.1    Rieff, H.I.2    Hollenbeck, P.J.3
  • 88
    • 0026779475 scopus 로고
    • Axonal and dendritic endocytic pathways in cultured neurons
    • R.G. Parton, K. Simons, and C.G. Dotti Axonal and dendritic endocytic pathways in cultured neurons J Cell Biol 119 1992 123 137
    • (1992) J Cell Biol , vol.119 , pp. 123-137
    • Parton, R.G.1    Simons, K.2    Dotti, C.G.3
  • 89
    • 0037698096 scopus 로고    scopus 로고
    • Presenilin-1, nicastrin, amyloid precursor protein, and gamma-secretase activity are co-localized in the lysosomal membrane
    • S.H. Pasternak, R.D. Bagshaw, M. Guiral, S. Zhang, C.A. Ackerley, and B.J. Pak Presenilin-1, nicastrin, amyloid precursor protein, and gamma-secretase activity are co-localized in the lysosomal membrane J Biol Chem 278 2003 26687 26694
    • (2003) J Biol Chem , vol.278 , pp. 26687-26694
    • Pasternak, S.H.1    Bagshaw, R.D.2    Guiral, M.3    Zhang, S.4    Ackerley, C.A.5    Pak, B.J.6
  • 90
    • 0000815355 scopus 로고
    • Neimann-Pick disease type C: A cellular cholesterol lipidosis
    • C. Scriver A. Beaudet W. Sly D. Valle McGraw Hill New York
    • P. Pentchev, M. Vanier, K. Suzuki, and M. Patterson Neimann-Pick disease type C: a cellular cholesterol lipidosis C. Scriver A. Beaudet W. Sly D. Valle The metabolic and molecular bases of inherited disease 1995 McGraw Hill New York 2625 2639
    • (1995) The Metabolic and Molecular Bases of Inherited Disease , pp. 2625-2639
    • Pentchev, P.1    Vanier, M.2    Suzuki, K.3    Patterson, M.4
  • 91
    • 0033516554 scopus 로고    scopus 로고
    • Mutagenesis identifies new signals for beta-amyloid precursor protein endocytosis, turnover, and the generation of secreted fragments, including Abeta42
    • R.G. Perez, S. Soriano, J.D. Hayes, B. Ostaszewski, W. Xia, and D.J. Selkoe Mutagenesis identifies new signals for beta-amyloid precursor protein endocytosis, turnover, and the generation of secreted fragments, including Abeta42 J Biol Chem 274 1999 18851 18856
    • (1999) J Biol Chem , vol.274 , pp. 18851-18856
    • Perez, R.G.1    Soriano, S.2    Hayes, J.D.3    Ostaszewski, B.4    Xia, W.5    Selkoe, D.J.6
  • 92
    • 0035252348 scopus 로고    scopus 로고
    • Trans-complex formation by proteolipid channels in the terminal phase of membrane fusion
    • C. Peters, M.J. Bayer, S. Buhler, J.S. Andersen, M. Mann, and A. Mayer Trans-complex formation by proteolipid channels in the terminal phase of membrane fusion Nature 409 2001 581 588
    • (2001) Nature , vol.409 , pp. 581-588
    • Peters, C.1    Bayer, M.J.2    Buhler, S.3    Andersen, J.S.4    Mann, M.5    Mayer, A.6
  • 95
    • 0034846497 scopus 로고    scopus 로고
    • Late endosomes: Sorting and partitioning in multivesicular bodies
    • R.C. Piper, and J.P. Luzio Late endosomes: sorting and partitioning in multivesicular bodies Traffic 2 2001 612 621
    • (2001) Traffic , vol.2 , pp. 612-621
    • Piper, R.C.1    Luzio, J.P.2
  • 98
    • 0037442526 scopus 로고    scopus 로고
    • D53 is a novel endosomal SNARE-binding protein that enhances interaction of syntaxin 1 with the synaptobrevin 2 complex in vitro
    • V. Proux-Gillardeaux, T. Galli, I. Callebaut, A. Mikhailik, G. Calothy, and M. Marx D53 is a novel endosomal SNARE-binding protein that enhances interaction of syntaxin 1 with the synaptobrevin 2 complex in vitro Biochem J 370 2003 213 221
    • (2003) Biochem J , vol.370 , pp. 213-221
    • Proux-Gillardeaux, V.1    Galli, T.2    Callebaut, I.3    Mikhailik, A.4    Calothy, G.5    Marx, M.6
  • 99
    • 0028132226 scopus 로고
    • Biology and genetics of prion diseases
    • S.B. Prusiner Biology and genetics of prion diseases Annu Rev Microbiol 48 1994 655 686
    • (1994) Annu Rev Microbiol , vol.48 , pp. 655-686
    • Prusiner, S.B.1
  • 100
    • 0842322740 scopus 로고    scopus 로고
    • Huntingtin bodies sequester vesicle-associated proteins by a polyproline-dependent interaction
    • Z.H. Qin, Y. Wang, E. Sapp, B. Cuiffo, E. Wanker, and M.R. Hayden Huntingtin bodies sequester vesicle-associated proteins by a polyproline-dependent interaction J Neurosci 24 2004 269 281
    • (2004) J Neurosci , vol.24 , pp. 269-281
    • Qin, Z.H.1    Wang, Y.2    Sapp, E.3    Cuiffo, B.4    Wanker, E.5    Hayden, M.R.6
  • 103
    • 0034474038 scopus 로고    scopus 로고
    • Loss of cation-independent mannose 6-phosphate receptor expression promotes the accumulation of lysobisphosphatidic acid in multilamellar bodies
    • B.J. Reaves, P.E. Row, N.A. Bright, J.P. Luzio, and H.W. Davidson Loss of cation-independent mannose 6-phosphate receptor expression promotes the accumulation of lysobisphosphatidic acid in multilamellar bodies J Cell Sci 113 Pt 22 2000 4099 4108
    • (2000) J Cell Sci , vol.113 , Issue.22 , pp. 4099-4108
    • Reaves, B.J.1    Row, P.E.2    Bright, N.A.3    Luzio, J.P.4    Davidson, H.W.5
  • 104
    • 0141642257 scopus 로고    scopus 로고
    • The hemicholinium-3 sensitive high affinity choline transporter is internalized by clathrin-mediated endocytosis and is present in endosomes and synaptic vesicles
    • F.M. Ribeiro, J. Alves-Silva, W. Volknandt, C. Martins-Silva, H. Mahmud, and A. Wilhelm The hemicholinium-3 sensitive high affinity choline transporter is internalized by clathrin-mediated endocytosis and is present in endosomes and synaptic vesicles J Neurochem 87 2003 136 146
    • (2003) J Neurochem , vol.87 , pp. 136-146
    • Ribeiro, F.M.1    Alves-Silva, J.2    Volknandt, W.3    Martins-Silva, C.4    Mahmud, H.5    Wilhelm, A.6
  • 105
    • 0033695839 scopus 로고    scopus 로고
    • Two endocytic recycling routes selectively fill two vesicle pools in frog motor nerve terminals
    • D.A. Richards, C. Guatimosim, and W.J. Betz Two endocytic recycling routes selectively fill two vesicle pools in frog motor nerve terminals Neuron 27 2000 551 559
    • (2000) Neuron , vol.27 , pp. 551-559
    • Richards, D.A.1    Guatimosim, C.2    Betz, W.J.3
  • 106
    • 0036715016 scopus 로고    scopus 로고
    • Niemann-Pick type C disease: Accelerated neurofibrillary tangle formation and amyloid beta deposition associated with apolipoprotein e epsilon 4 homozygosity
    • Y. Saito, K. Suzuki, E. Nanba, T. Yamamoto, K. Ohno, and S. Murayama Niemann-Pick type C disease: accelerated neurofibrillary tangle formation and amyloid beta deposition associated with apolipoprotein E epsilon 4 homozygosity Ann Neurol 52 2002 351 355
    • (2002) Ann Neurol , vol.52 , pp. 351-355
    • Saito, Y.1    Suzuki, K.2    Nanba, E.3    Yamamoto, T.4    Ohno, K.5    Murayama, S.6
  • 107
    • 0037340949 scopus 로고    scopus 로고
    • Promotion of tau phosphorylation by MAP kinase Erk1/2 is accompanied by reduced cholesterol level in detergent-insoluble membrane fraction in Niemann-Pick C1-deficient cells
    • N. Sawamura, J.S. Gong, T.Y. Chang, K. Yanagisawa, and M. Michikawa Promotion of tau phosphorylation by MAP kinase Erk1/2 is accompanied by reduced cholesterol level in detergent-insoluble membrane fraction in Niemann-Pick C1-deficient cells J Neurochem 84 2003 1086 1096
    • (2003) J Neurochem , vol.84 , pp. 1086-1096
    • Sawamura, N.1    Gong, J.S.2    Chang, T.Y.3    Yanagisawa, K.4    Michikawa, M.5
  • 108
    • 0035971218 scopus 로고    scopus 로고
    • Site-specific phosphorylation of tau accompanied by activation of mitogen-activated protein kinase (MAPK) in brains of Niemann-Pick type C mice
    • N. Sawamura, J.S. Gong, W.S. Garver, R.A. Heidenreich, H. Ninomiya, and K. Ohno Site-specific phosphorylation of tau accompanied by activation of mitogen-activated protein kinase (MAPK) in brains of Niemann-Pick type C mice J Biol Chem 276 2001 10314 10319
    • (2001) J Biol Chem , vol.276 , pp. 10314-10319
    • Sawamura, N.1    Gong, J.S.2    Garver, W.S.3    Heidenreich, R.A.4    Ninomiya, H.5    Ohno, K.6
  • 109
    • 0032786710 scopus 로고    scopus 로고
    • Spatial relationship of AMY protein deposits and different species of Abeta peptides in amyloid plaques of the Alzheimer disease brain
    • M.L. Schmidt, T.C. Saido, V.M. Lee, and J.Q. Trojanowski Spatial relationship of AMY protein deposits and different species of Abeta peptides in amyloid plaques of the Alzheimer disease brain J Neuropathol Exp Neurol 58 1999 1227 1233
    • (1999) J Neuropathol Exp Neurol , vol.58 , pp. 1227-1233
    • Schmidt, M.L.1    Saido, T.C.2    Lee, V.M.3    Trojanowski, J.Q.4
  • 110
    • 0036606805 scopus 로고    scopus 로고
    • When cell biology meets development: Endocytic regulation of signaling pathways
    • E.S. Seto, H.J. Bellen, and T.E. Lloyd When cell biology meets development: endocytic regulation of signaling pathways Genes Dev 16 2002 1314 1336
    • (2002) Genes Dev , vol.16 , pp. 1314-1336
    • Seto, E.S.1    Bellen, H.J.2    Lloyd, T.E.3
  • 111
    • 0032538838 scopus 로고    scopus 로고
    • Neuroendocrine synaptic vesicles are formed in vitro by both clathrin-dependent and clathrin-independent pathways
    • G. Shi, V. Faundez, J. Roos, E.C. Dell'Angelica, and R.B. Kelly Neuroendocrine synaptic vesicles are formed in vitro by both clathrin-dependent and clathrin-independent pathways J Cell Biol 143 1998 947 955
    • (1998) J Cell Biol , vol.143 , pp. 947-955
    • Shi, G.1    Faundez, V.2    Roos, J.3    Dell'Angelica, E.C.4    Kelly, R.B.5
  • 112
    • 0041827375 scopus 로고    scopus 로고
    • An essential role of Rab5 in uniformity of synaptic vesicle size
    • H. Shimizu, S. Kawamura, and K. Ozaki An essential role of Rab5 in uniformity of synaptic vesicle size J Cell Sci 116 2003 3583 3590
    • (2003) J Cell Sci , vol.116 , pp. 3583-3590
    • Shimizu, H.1    Kawamura, S.2    Ozaki, K.3
  • 113
    • 0034332917 scopus 로고    scopus 로고
    • Jamming the endosomal system: Lipid rafts and lysosomal storage diseases
    • K. Simons, and J. Gruenberg Jamming the endosomal system: lipid rafts and lysosomal storage diseases Trends Cell Biol 10 2000 459 462
    • (2000) Trends Cell Biol , vol.10 , pp. 459-462
    • Simons, K.1    Gruenberg, J.2
  • 114
    • 0036548070 scopus 로고    scopus 로고
    • Gamma-Secretase, Notch, Abeta and Alzheimer's disease: Where do the presenilins fit in?
    • S.S. Sisodia, and P.H. St George-Hyslop gamma-Secretase, Notch, Abeta and Alzheimer's disease: where do the presenilins fit in? Nat Rev Neurosci 3 2002 281 290
    • (2002) Nat Rev Neurosci , vol.3 , pp. 281-290
    • Sisodia, S.S.1    St George-Hyslop, P.H.2
  • 115
    • 0034941330 scopus 로고    scopus 로고
    • Nerve growth factor signaling, neuroprotection, and neural repair
    • M.V. Sofroniew, C.L. Howe, and W.C. Mobley Nerve growth factor signaling, neuroprotection, and neural repair Annu Rev Neurosci 24 2001 1217 1281
    • (2001) Annu Rev Neurosci , vol.24 , pp. 1217-1281
    • Sofroniew, M.V.1    Howe, C.L.2    Mobley, W.C.3
  • 116
    • 0033527744 scopus 로고    scopus 로고
    • Expression of beta-amyloid precursor protein-CD3gamma chimeras to demonstrate the selective generation of amyloid beta(1-40) and amyloid beta(1-42) peptides within secretory and endocytic compartments
    • S. Soriano, A.S. Chyung, X. Chen, G.B. Stokin, V.M. Lee, and E.H. Koo Expression of beta-amyloid precursor protein-CD3gamma chimeras to demonstrate the selective generation of amyloid beta(1-40) and amyloid beta(1-42) peptides within secretory and endocytic compartments J Biol Chem 274 1999 32295 32300
    • (1999) J Biol Chem , vol.274 , pp. 32295-32300
    • Soriano, S.1    Chyung, A.S.2    Chen, X.3    Stokin, G.B.4    Lee, V.M.5    Koo, E.H.6
  • 117
    • 0036341207 scopus 로고    scopus 로고
    • Signal transduction and endocytosis: Close encounters of many kinds
    • A. Sorkin, and M. Von Zastrow Signal transduction and endocytosis: close encounters of many kinds Nat Rev Mol Cell Biol 3 2002 600 614
    • (2002) Nat Rev Mol Cell Biol , vol.3 , pp. 600-614
    • Sorkin, A.1    Von Zastrow, M.2
  • 118
    • 0037075547 scopus 로고    scopus 로고
    • Cbl-CIN85-endophilin complex mediates ligand-induced downregulation of EGF receptors
    • P. Soubeyran, K. Kowanetz, I. Szymkiewicz, W.Y. Langdon, and I. Dikic Cbl-CIN85-endophilin complex mediates ligand-induced downregulation of EGF receptors Nature 416 2002 183 187
    • (2002) Nature , vol.416 , pp. 183-187
    • Soubeyran, P.1    Kowanetz, K.2    Szymkiewicz, I.3    Langdon, W.Y.4    Dikic, I.5
  • 119
    • 0033637985 scopus 로고    scopus 로고
    • The synaptic vesicle cycle revisited
    • T.C. Sudhof The synaptic vesicle cycle revisited Neuron 28 2000 317 320
    • (2000) Neuron , vol.28 , pp. 317-320
    • Sudhof, T.C.1
  • 120
    • 0035950188 scopus 로고    scopus 로고
    • New frontiers in Alzheimer's disease genetics
    • R.E. Tanzi, and L. Bertram New frontiers in Alzheimer's disease genetics Neuron 32 2001 181 184
    • (2001) Neuron , vol.32 , pp. 181-184
    • Tanzi, R.E.1    Bertram, L.2
  • 121
    • 0025373111 scopus 로고
    • Scrapie prion proteins accumulate in the cytoplasm of persistently infected cultured cells
    • A. Taraboulos, D. Serban, and S.B. Prusiner Scrapie prion proteins accumulate in the cytoplasm of persistently infected cultured cells J Cell Biol 110 1990 2117 2132
    • (1990) J Cell Biol , vol.110 , pp. 2117-2132
    • Taraboulos, A.1    Serban, D.2    Prusiner, S.B.3
  • 122
    • 0036047004 scopus 로고    scopus 로고
    • Axonal transport, tau protein, and neurodegeneration in Alzheimer's disease
    • D. Terwel, L. Dewachter, and F. Van Leuven Axonal transport, tau protein, and neurodegeneration in Alzheimer's disease Neuromolecular Med 2 2002 151 165
    • (2002) Neuromolecular Med , vol.2 , pp. 151-165
    • Terwel, D.1    Dewachter, L.2    Van Leuven, F.3
  • 124
    • 0028346560 scopus 로고
    • CD45: An emerging role as a protein tyrosine phosphatase required for lymphocyte activation and development
    • I.S. Trowbridge, and M.L. Thomas CD45: an emerging role as a protein tyrosine phosphatase required for lymphocyte activation and development Annu Rev Immunol 12 1994 85 116
    • (1994) Annu Rev Immunol , vol.12 , pp. 85-116
    • Trowbridge, I.S.1    Thomas, M.L.2
  • 125
    • 0141886877 scopus 로고    scopus 로고
    • Niemann-Pick disease type C
    • M.T. Vanier, and G. Millat Niemann-Pick disease type C Clin Genet 64 2003 269 281
    • (2003) Clin Genet , vol.64 , pp. 269-281
    • Vanier, M.T.1    Millat, G.2
  • 126
    • 0033595706 scopus 로고    scopus 로고
    • Beta-Secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE
    • R. Vassar, B.D. Bennett, S. Babu-Khan, S. Kahn, E.A. Mendiaz, and P. Denis Beta-Secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE Science 286 1999 735 741
    • (1999) Science , vol.286 , pp. 735-741
    • Vassar, R.1    Bennett, B.D.2    Babu-Khan, S.3    Kahn, S.4    Mendiaz, E.A.5    Denis, P.6
  • 127
    • 0037396865 scopus 로고    scopus 로고
    • Understanding Niemann-Pick type C disease: A fat problem
    • I. Vincent, B. Bu, and R.P. Erickson Understanding Niemann-Pick type C disease: a fat problem Curr Opin Neurol 16 2003 155 161
    • (2003) Curr Opin Neurol , vol.16 , pp. 155-161
    • Vincent, I.1    Bu, B.2    Erickson, R.P.3
  • 128
    • 0029671219 scopus 로고    scopus 로고
    • Interfering with apoptosis: Ca(2+)-binding protein ALG-2 and Alzheimer's disease gene ALG-3
    • P. Vito, E. Lacana, and L. D'Adamio Interfering with apoptosis: Ca(2+)-binding protein ALG-2 and Alzheimer's disease gene ALG-3 Science 271 1996 521 525
    • (1996) Science , vol.271 , pp. 521-525
    • Vito, P.1    Lacana, E.2    D'Adamio, L.3
  • 129
    • 0033556043 scopus 로고    scopus 로고
    • Cloning of AIP1, a novel protein that associates with the apoptosis-linked gene ALG-2 in a Ca2+-dependent reaction
    • P. Vito, L. Pellegrini, C. Guiet, and L. D'Adamio Cloning of AIP1, a novel protein that associates with the apoptosis-linked gene ALG-2 in a Ca2+-dependent reaction J Biol Chem 274 1999 1533 1540
    • (1999) J Biol Chem , vol.274 , pp. 1533-1540
    • Vito, P.1    Pellegrini, L.2    Guiet, C.3    D'Adamio, L.4
  • 131
    • 0035880457 scopus 로고    scopus 로고
    • The huntingtin interacting protein HIP1 is a clathrin and alpha-adaptin-binding protein involved in receptor-mediated endocytosis
    • S. Waelter, E. Scherzinger, R. Hasenbank, E. Nordhoff, R. Lurz, and H. Goehler The huntingtin interacting protein HIP1 is a clathrin and alpha-adaptin-binding protein involved in receptor-mediated endocytosis Hum Mol Genet 10 2001 1807 1817
    • (2001) Hum Mol Genet , vol.10 , pp. 1807-1817
    • Waelter, S.1    Scherzinger, E.2    Hasenbank, R.3    Nordhoff, E.4    Lurz, R.5    Goehler, H.6
  • 132
    • 0036669881 scopus 로고    scopus 로고
    • Amyloid-beta oligomers: Their production, toxicity and therapeutic inhibition
    • D.M. Walsh, I. Klyubin, J.V. Fadeeva, M.J. Rowan, and D.J. Selkoe Amyloid-beta oligomers: their production, toxicity and therapeutic inhibition Biochem Soc Trans 30 2002 552 557
    • (2002) Biochem Soc Trans , vol.30 , pp. 552-557
    • Walsh, D.M.1    Klyubin, I.2    Fadeeva, J.V.3    Rowan, M.J.4    Selkoe, D.J.5
  • 133
    • 0035805592 scopus 로고    scopus 로고
    • Phosphorylation regulates intracellular trafficking of beta-secretase
    • J. Walter, R. Fluhrer, B. Hartung, M. Willem, C. Kaether, and A. Capell Phosphorylation regulates intracellular trafficking of beta-secretase J Biol Chem 276 2001 14634 14641
    • (2001) J Biol Chem , vol.276 , pp. 14634-14641
    • Walter, J.1    Fluhrer, R.2    Hartung, B.3    Willem, M.4    Kaether, C.5    Capell, A.6
  • 135
    • 0029792928 scopus 로고    scopus 로고
    • New clues to Alzheimer's disease: Unraveling the roles of amyloid and tau
    • B.A. Yankner New clues to Alzheimer's disease: unraveling the roles of amyloid and tau Nat Med 2 1996 850 852
    • (1996) Nat Med , vol.2 , pp. 850-852
    • Yankner, B.A.1
  • 136
    • 4344689871 scopus 로고    scopus 로고
    • Autophagic vacuoles are enriched in amyloid precursor protein-secretase activities: Implications for b-amyloid peptide over-production and localization in Alzheimer's disease
    • Yu WH, Kumar A, Peterhoff CM, Shapiro-Kulnane L, Uchiyama Y, Lamb BT, et al. Autophagic vacuoles are enriched in amyloid precursor protein-secretase activities: implications for b-amyloid peptide over-production and localization in Alzheimer's disease. Int J Biochem Cell Biol 2004;36:2531-40.
    • (2004) Int J Biochem Cell Biol , vol.36 , pp. 2531-2540
    • Yu, W.H.1    Kumar, A.2    Peterhoff, C.M.3    Shapiro-Kulnane, L.4    Uchiyama, Y.5    Lamb, B.T.6
  • 137
    • 0035142802 scopus 로고    scopus 로고
    • Neurons in Niemann-Pick disease type C accumulate gangliosides as well as unesterified cholesterol and undergo dendritic and axonal alterations
    • M. Zervas, K. Dobrenis, and S.U. Walkley Neurons in Niemann-Pick disease type C accumulate gangliosides as well as unesterified cholesterol and undergo dendritic and axonal alterations J Neuropathol Exp Neurol 60 2001 49 64
    • (2001) J Neuropathol Exp Neurol , vol.60 , pp. 49-64
    • Zervas, M.1    Dobrenis, K.2    Walkley, S.U.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.