Removal of pattern-breaking sequences in microtubule binding repeats produces instantaneous tau aggregation and toxicity

Journal of Biological Chemistry

Volumn 281, Issue 48, 2006, Pages 37195-37204

  Iliev, Asparouh Iliev ^a   Ganesan, Sundar ^a   Bunt, Gertrude ^b   Wouters, Fred Silvester ^a  

^a EUROPEAN NEUROSCIENCE INSTITUTE   (Germany)

^b MAX PLANCK INSTITUTE OF EXPERIMENTAL MEDICINE   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AGGLOMERATION; AMINO ACIDS; CELLS; CONFORMATIONS; DISEASES; MUTAGENESIS; PATHOLOGY; TOXICITY;

ALZHEIMER'S DISEASE (AD); CONFORMATIONAL EPITOPES; CYTOTOXICITY; MICROTUBULES; PHOSPHORYLATED TAU PROTEIN;

PROTEINS;

EPITOPE; MUTANT PROTEIN; SERINE; TAU PROTEIN;

ARTICLE; CELL DAMAGE; CYTOTOXICITY; FLUORESCENCE RECOVERY AFTER PHOTOBLEACHING; MICROTUBULE; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN MODIFICATION; PROTEIN PHOSPHORYLATION;

AMINO ACID SEQUENCE; ANIMALS; CELL LINE, TUMOR; CHO CELLS; CRICETINAE; EPITOPES; HIPPOCAMPUS; HUMANS; MICE; MICE, INBRED C57BL; MICROTUBULES; MOLECULAR SEQUENCE DATA; NEURONS; PHOSPHORYLATION; SEQUENCE HOMOLOGY, AMINO ACID; TAU PROTEINS;

EID: 33845974450     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M604863200     Document Type: Article

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