-
1
-
-
0018344553
-
Memory deficits associated with senescence a neurophysiological and behavioral study in the rat
-
Barnes CA (1979) Memory deficits associated with senescence: a neurophysiological and behavioral study in the rat. J Comp Physiol Psychol 93:74-104.
-
(1979)
J Comp Physiol Psychol
, vol.93
, pp. 74-104
-
-
Barnes, C.A.1
-
2
-
-
14644442872
-
Intraneuronal Abeta causes the onset of early Alzheimer's disease-related cognitive deficits in transgenic mice
-
Billings LM, Oddo S, Green KN, McGaugh JL, LaFerla FM (2005) Intraneuronal Abeta causes the onset of early Alzheimer's disease-related cognitive deficits in transgenic mice. Neuron 45:675-688.
-
(2005)
Neuron
, vol.45
, pp. 675-688
-
-
Billings, L.M.1
Oddo, S.2
Green, K.N.3
McGaugh, J.L.4
Laferla, F.M.5
-
3
-
-
33750200403
-
Estradiol-induced modulation of estrogen receptor-beta and GABA within the adult neocortex a potential transsynaptic mechanism for estrogen modulation of BDNF
-
Blurton-Jones M, Tuszynski MH (2006) Estradiol-induced modulation of estrogen receptor-beta and GABA within the adult neocortex: a potential transsynaptic mechanism for estrogen modulation of BDNF. J Comp Neurol 499:603-612.
-
(2006)
J Comp Neurol
, vol.499
, pp. 603-612
-
-
Blurton-Jones, M.1
Tuszynski, M.H.2
-
4
-
-
34548738209
-
Age-dependent sexual dimorphism in cognition and stress response in the 3xTg-AD mice
-
DOI 10.1016/j.nbd.2007.06.013, PII S0969996107001350
-
Clinton LK, Billings LM, Green KN, Caccamo A, Ngo J, Oddo S, McGaugh JL, LaFerla FM (2007) Age-dependent sexual dimorphism in cognition and stress response in the 3xTg-AD mice. Neurobiol Dis 28:76-82. (Pubitemid 47429975)
-
(2007)
Neurobiology of Disease
, vol.28
, Issue.1
, pp. 76-82
-
-
Clinton, L.K.1
Billings, L.M.2
Green, K.N.3
Caccamo, A.4
Ngo, J.5
Oddo, S.6
McGaugh, J.L.7
Laferla, F.M.8
-
5
-
-
0027528829
-
The Lewy-body variant of Alzheimer's disease. Clinical and pathological findings
-
Förstl H, Burns A, Luthert P, Cairns N, Levy R (1993) The Lewy-body variant of Alzheimer's disease. Clinical and pathological findings. Br J Psychiatry 162:385-392. (Pubitemid 23070204)
-
(1993)
British Journal of Psychiatry
, vol.162
, Issue.MAR
, pp. 385-392
-
-
Forstl, H.1
Burns, A.2
Luthert, P.3
Cairns, N.4
Levy, R.5
-
6
-
-
14844311246
-
Tau phosphorylation increases in symptomatic mice overexpressing A30P alpha-synuclein
-
DOI 10.1016/j.expneurol.2004.07.016
-
Frasier M, Walzer M, McCarthy L, Magnuson D, Lee JM, Haas C, Kahle P, Wolozin B (2005) Tau phosphorylation increases in symptomatic mice overexpressing A30P alpha-synuclein. Exp Neurol 192:274-287. (Pubitemid 40347257)
-
(2005)
Experimental Neurology
, vol.192
, Issue.2
, pp. 274-287
-
-
Frasier, M.1
Walzer, M.2
McCarthy, L.3
Magnuson, D.4
Lee, J.M.5
Haas, C.6
Kahle, P.7
Wolozin, B.8
-
7
-
-
34447570901
-
Age-dependent cognitive decline and amygdala pathology in alpha-synuclein transgenic mice
-
DOI 10.1016/j.neurobiolaging.2006.06.013, PII S0197458006002235
-
Freichel C, Neumann M, Ballard T, Müller V, Woolley M, Ozmen L, Borroni E, Kretzschmar HA, Haass C, Spooren W, Kahle PJ (2007) Age-dependent cognitive decline and amygdala pathology in alpha-synuclein transgenic mice. Neurobiol Aging 28:1421-1435. (Pubitemid 47081234)
-
(2007)
Neurobiology of Aging
, vol.28
, Issue.9
, pp. 1421-1435
-
-
Freichel, C.1
Neumann, M.2
Ballard, T.3
Muller, V.4
Woolley, M.5
Ozmen, L.6
Borroni, E.7
Kretzschmar, H.A.8
Haass, C.9
Spooren, W.10
Kahle, P.J.11
-
8
-
-
0036174010
-
Alpha-Synuclein is phosphorylated in synucleinopathy lesions
-
Fujiwara H, Hasegawa M, Dohmae N, Kawashima A, Masliah E, Goldberg MS, Shen J, Takio K, Iwatsubo T (2002) alpha-Synuclein is phosphorylated in synucleinopathy lesions. Nat Cell Biol 4:160-164.
-
(2002)
Nat Cell Biol
, vol.4
, pp. 160-164
-
-
Fujiwara, H.1
Hasegawa, M.2
Dohmae, N.3
Kawashima, A.4
Masliah, E.5
Goldberg, M.S.6
Shen, J.7
Takio, K.8
Iwatsubo, T.9
-
9
-
-
0037118259
-
Neuronal alpha-synucleinopathy with severe movement disorder in mice expressing A53T human alpha-synuclein
-
Giasson BI, Duda JE, Quinn SM, Zhang B, Trojanowski JQ, Lee VM (2002) Neuronal alpha-synucleinopathy with severe movement disorder in mice expressing A53T human alpha-synuclein. Neuron 34:521-533.
-
(2002)
Neuron
, vol.34
, pp. 521-533
-
-
Giasson, B.I.1
Duda, J.E.2
Quinn, S.M.3
Zhang, B.4
Trojanowski, J.Q.5
Lee, V.M.6
-
10
-
-
0037466656
-
Initiation and synergistic fibrillization of tau and alpha-synuclein
-
Giasson BI, Forman MS, Higuchi M, Golbe LI, Graves CL, Kotzbauer PT, Trojanowski JQ, Lee VM (2003) Initiation and synergistic fibrillization of tau and alpha-synuclein. Science 300:636-640.
-
(2003)
Science
, vol.300
, pp. 636-640
-
-
Giasson, B.I.1
Forman, M.S.2
Higuchi, M.3
Golbe, L.I.4
Graves, C.L.5
Kotzbauer, P.T.6
Trojanowski, J.Q.7
Lee, V.M.8
-
11
-
-
0033919992
-
Lewy bodies in Alzheimer's disease: A neuropathological review of 145 cases using alpha-synuclein immunohistochemistry
-
Hamilton RL (2000) Lewy bodies in Alzheimer's disease: a neuropathological review of 145 cases using alpha-synuclein immunohistochemistry. Brain Pathol 10:378-384.
-
(2000)
Brain Pathol
, vol.10
, pp. 378-384
-
-
Hamilton, R.L.1
-
12
-
-
0025061059
-
The Lewy body variant of Alzheimer's disease: A clinical and pathologic entity
-
Hansen L, Salmon D, Galasko D, Masliah E, Katzman R, DeTeresa R, Thal L, Pay MM, Hofstetter R, Klauber M, Rice V, Butters N, Alford M (1990) The Lewy body variant of Alzheimer's disease: a clinical and pathologic entity. Neurology 40:1-8.
-
(1990)
Neurology
, vol.40
, pp. 1-8
-
-
Hansen, L.1
Salmon, D.2
Galasko, D.3
Masliah, E.4
Katzman, R.5
Deteresa, R.6
Thal, L.7
Pay, M.M.8
Hofstetter, R.9
Klauber, M.10
Rice, V.11
Butters, N.12
Alford, M.13
-
13
-
-
0027258525
-
The carboxy terminus of the beta amyloid protein is critical for the seeding of amyloid formation: Implications for the pathogenesis of Alzheimer's disease
-
Jarrett JT, Berger EP, Lansbury PT Jr (1993) The carboxy terminus of the beta amyloid protein is critical for the seeding of amyloid formation: implications for the pathogenesis of Alzheimer's disease. Biochemistry 32:4693-4697.
-
(1993)
Biochemistry
, vol.32
, pp. 4693-4697
-
-
Jarrett, J.T.1
Berger, E.P.2
Lansbury Jr., P.T.3
-
14
-
-
2342556414
-
Fibrillization of alpha-synuclein and tau in familial Parkinson's disease caused by the A53T alpha-synuclein mutation
-
Kotzbauer PT, Giasson BI, Kravitz AV, Golbe LI, Mark MH, Trojanowski JQ, Lee VM (2004) Fibrillization of alpha-synuclein and tau in familial Parkinson's disease caused by the A53T alpha-synuclein mutation. Exp Neurol 187:279-288.
-
(2004)
Exp Neurol
, vol.187
, pp. 279-288
-
-
Kotzbauer, P.T.1
Giasson, B.I.2
Kravitz, A.V.3
Golbe, L.I.4
Mark, M.H.5
Trojanowski, J.Q.6
Lee, V.M.7
-
15
-
-
21144441564
-
Cognitive differences in dementia patients with autopsy-verified AD, Lewy body pathology, or both
-
Kraybill ML, Larson EB, Tsuang DW, Teri L, McCormick WC, Bowen JD, Kukull WA, Leverenz JB, Cherrier MM (2005) Cognitive differences in dementia patients with autopsy-verified AD, Lewy body pathology, or both. Neurology 64:2069-2073.
-
(2005)
Neurology
, vol.64
, pp. 2069-2073
-
-
Kraybill, M.L.1
Larson, E.B.2
Tsuang, D.W.3
Teri, L.4
McCormick, W.C.5
Bowen, J.D.6
Kukull, W.A.7
Leverenz, J.B.8
Cherrier, M.M.9
-
16
-
-
0027500963
-
Neurotransmitters in basal ganglia and cortex of Alzheimer's disease with and without Lewy bodies
-
Langlais PJ, Thal L, Hansen L, Galasko D, Alford M, Masliah E (1993) Neurotransmitters in basal ganglia and cortex of Alzheimer's disease with and without Lewy bodies. Neurology 43:1927-1934. (Pubitemid 23318857)
-
(1993)
Neurology
, vol.43
, Issue.10
, pp. 1927-1934
-
-
Langlais, P.J.1
Thal, L.2
Hansen, L.3
Galasko, D.4
Alford, M.5
Masliah, E.6
-
17
-
-
21344456506
-
Intravesicular localization and exocytosis of α-synuclein and its aggregates
-
Lee HJ, Patel S, Lee SJ (2005) Intravesicular localization and exocytosis of α-synuclein and its aggregates. J Neurosci 25:6016-6024.
-
(2005)
J Neurosci
, vol.25
, pp. 6016-6024
-
-
Lee, H.J.1
Patel, S.2
Lee, S.J.3
-
18
-
-
1342321775
-
More than just two peas in a pod: Common amyloidogenic properties of tau and alpha-synuclein in neurodegenerative diseases
-
Lee VM, Giasson BI, Trojanowski JQ (2004) More than just two peas in a pod: common amyloidogenic properties of tau and alpha-synuclein in neurodegenerative diseases. Trends Neurosci 27:129-134.
-
(2004)
Trends Neurosci
, vol.27
, pp. 129-134
-
-
Lee, V.M.1
Giasson, B.I.2
Trojanowski, J.Q.3
-
19
-
-
10744233138
-
Genetic background regulates beta-amyloid precursor protein processing and beta-amyloid deposition in the mouse
-
Lehman EJ, Kulnane LS, Gao Y, Petriello MC, Pimpis KM, Younkin L, Dolios G, Wang R, Younkin SG, Lamb BT (2003) Genetic background regulates beta-amyloid precursor protein processing and beta-amyloid deposition in the mouse. Hum Mol Genet 12:2949-2956.
-
(2003)
Hum Mol Genet
, vol.12
, pp. 2949-2956
-
-
Lehman, E.J.1
Kulnane, L.S.2
Gao, Y.3
Petriello, M.C.4
Pimpis, K.M.5
Younkin, L.6
Dolios, G.7
Wang, R.8
Younkin, S.G.9
Lamb, B.T.10
-
20
-
-
33748584602
-
Interaction between Abeta peptide and alpha synuclein: Molecular mechanisms in overlapping pathology of Alzheimer's and Parkinson's in dementia with Lewy body disease
-
Mandal PK, Pettegrew JW, Masliah E, Hamilton RL, Mandal R (2006) Interaction between Abeta peptide and alpha synuclein: molecular mechanisms in overlapping pathology of Alzheimer's and Parkinson's in dementia with Lewy body disease. Neurochem Res 31:1153-1162.
-
(2006)
Neurochem Res
, vol.31
, pp. 1153-1162
-
-
Mandal, P.K.1
Pettegrew, J.W.2
Masliah, E.3
Hamilton, R.L.4
Mandal, R.5
-
21
-
-
0035834076
-
β-Amyloid peptides enhance α-synuclein accumulation and neuronal deficits in a transgenic mouse model linking Alzheimer's disease and Parkinson's disease
-
Masliah E, Rockenstein E, Veinbergs I, Sagara Y, Mallory M, Hashimoto M, Mucke L (2001) β-Amyloid peptides enhance α-synuclein accumulation and neuronal deficits in a transgenic mouse model linking Alzheimer's disease and Parkinson's disease. Proc Natl Acad Sci U S A 98:12245-12250.
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 12245-12250
-
-
Masliah, E.1
Rockenstein, E.2
Veinbergs, I.3
Sagara, Y.4
Mallory, M.5
Hashimoto, M.6
Mucke, L.7
-
22
-
-
0042697305
-
Triple-transgenic model of Alzheimer's disease with plaques and tangles: Intracellular Abeta and synaptic dysfunction
-
Oddo S, Caccamo A, Shepherd JD, Murphy MP, Golde TE, Kayed R, Metherate R, Mattson MP, Akbari Y, LaFerla FM (2003) Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular Abeta and synaptic dysfunction. Neuron 39:409-421.
-
(2003)
Neuron
, vol.39
, pp. 409-421
-
-
Oddo, S.1
Caccamo, A.2
Shepherd, J.D.3
Murphy, M.P.4
Golde, T.E.5
Kayed, R.6
Metherate, R.7
Mattson, M.P.8
Akbari, Y.9
LaFerla, F.M.10
-
23
-
-
4043167747
-
Abeta immunotherapy leads to clearance of early, but not late, hyperphosphorylated tau aggregates via the proteasome
-
Oddo S, Billings L, Kesslak JP, Cribbs DH, LaFerla FM (2004) Abeta immunotherapy leads to clearance of early, but not late, hyperphosphorylated tau aggregates via the proteasome. Neuron 43:321-332.
-
(2004)
Neuron
, vol.43
, pp. 321-332
-
-
Oddo, S.1
Billings, L.2
Kesslak, J.P.3
Cribbs, D.H.4
LaFerla, F.M.5
-
24
-
-
33144487701
-
Temporal profile of amyloid-beta (Abeta) oligomerization in an in vivo model of Alzheimer disease. a link between Abeta and tau pathology
-
Oddo S, Caccamo A, Tran L, Lambert MP, Glabe CG, Klein WL, LaFerla FM (2006) Temporal profile of amyloid-beta (Abeta) oligomerization in an in vivo model of Alzheimer disease. A link between Abeta and tau pathology. J Biol Chem 281:1599-1604.
-
(2006)
J Biol Chem
, vol.281
, pp. 1599-1604
-
-
Oddo, S.1
Caccamo, A.2
Tran, L.3
Lambert, M.P.4
Glabe, C.G.5
Klein, W.L.6
LaFerla, F.M.7
-
25
-
-
0034614415
-
Constitutive phosphorylation of the Parkinson's disease associated alpha-synuclein
-
Okochi M, Walter J, Koyama A, Nakajo S, Baba M, Iwatsubo T, Meijer L, Kahle PJ, Haass C (2000) Constitutive phosphorylation of the Parkinson's disease associated alpha-synuclein. J Biol Chem 275:390-397.
-
(2000)
J Biol Chem
, vol.275
, pp. 390-397
-
-
Okochi, M.1
Walter, J.2
Koyama, A.3
Nakajo, S.4
Baba, M.5
Iwatsubo, T.6
Meijer, L.7
Kahle, P.J.8
Haass, C.9
-
26
-
-
0031722580
-
Cognitive decline is faster in Lewy body variant than in Alzheimer's disease
-
Olichney JM, Galasko D, Salmon DP, Hofstetter CR, Hansen LA, Katzman R, Thal LJ (1998) Cognitive decline is faster in Lewy body variant than in Alzheimer's disease. Neurology 51:351-357. (Pubitemid 28406305)
-
(1998)
Neurology
, vol.51
, Issue.2
, pp. 351-357
-
-
Olichney, J.M.1
Galasko, D.2
Salmon, D.P.3
Hofstetter, C.R.4
Hansen, L.A.5
Katzman, R.6
Thal, L.J.7
-
27
-
-
42149165496
-
A closer look at alpha-secretase
-
Postina R (2008) A closer look at alpha-secretase. Curr Alzheimer Res 5:179-186.
-
(2008)
Curr Alzheimer Res
, vol.5
, pp. 179-186
-
-
Postina, R.1
-
28
-
-
0027535896
-
Detection of Lewy bodies in trisomy 21 (Down's syndrome)
-
Raghavan R, Khin-Nu C, Brown A, Irving D, Ince PG, Day K, Tyrer SP, Perry RH (1993) Detection of Lewy bodies in trisomy 21 (Down's syndrome). Can J Neurol Sci 20:48-51.
-
(1993)
Can J Neurol Sci
, vol.20
, pp. 48-51
-
-
Raghavan, R.1
Khin-Nu, C.2
Brown, A.3
Irving, D.4
Ince, P.G.5
Day, K.6
Tyrer, S.P.7
Perry, R.H.8
-
29
-
-
20444416315
-
α-Synuclein phosphorylation enhances eosinophilic cytoplasmic inclusion formation in SH-SY5Y cells
-
Smith WW, Margolis RL, Li X, Troncoso JC, Lee MK, Dawson VL, Dawson TM, Iwatsubo T, Ross CA (2005) α-Synuclein phosphorylation enhances eosinophilic cytoplasmic inclusion formation in SH-SY5Y cells. J Neurosci 25:5544-5552.
-
(2005)
J Neurosci
, vol.25
, pp. 5544-5552
-
-
Smith, W.W.1
Margolis, R.L.2
Li, X.3
Troncoso, J.C.4
Lee, M.K.5
Dawson, V.L.6
Dawson, T.M.7
Iwatsubo, T.8
Ross, C.A.9
-
30
-
-
0028322017
-
An increased percentage of long amyloid beta protein secreted by familial amyloid beta protein precursor (beta APP717) mutants
-
Suzuki N, Cheung TT, Cai XD, Odaka A, Otvos L Jr, Eckman C, Golde TE, Younkin SG (1994) An increased percentage of long amyloid beta protein secreted by familial amyloid beta protein precursor (beta APP717) mutants. Science 264:1336-1340.
-
(1994)
Science
, vol.264
, pp. 1336-1340
-
-
Suzuki, N.1
Cheung, T.T.2
Cai, X.D.3
Odaka, A.4
Otvos Jr., L.5
Eckman, C.6
Golde, T.E.7
Younkin, S.G.8
-
31
-
-
0036827419
-
Emerging Alzheimer's disease therapies: Focusing on the future
-
Trojanowski JQ (2002) "Emerging Alzheimer's disease therapies: focusing on the future." Neurobiol Aging 23:985-990.
-
(2002)
Neurobiol Aging
, vol.23
, pp. 985-990
-
-
Trojanowski, J.Q.1
-
32
-
-
52349111812
-
Mechanisms of hybrid oligomer formation in the pathogenesis of combined Alzheimer's and Parkinson's diseases
-
Tsigelny IF, Crews L, Desplats P, Shaked GM, Sharikov Y, Mizuno H, Spencer B, Rockenstein E, Trejo M, Platoshyn O, Yuan JX, Masliah E (2008) Mechanisms of hybrid oligomer formation in the pathogenesis of combined Alzheimer's and Parkinson's diseases. PLoS ONE 3:e3135.
-
(2008)
PLoS ONE
, vol.3
-
-
Tsigelny, I.F.1
Crews, L.2
Desplats, P.3
Shaked, G.M.4
Sharikov, Y.5
Mizuno, H.6
Spencer, B.7
Rockenstein, E.8
Trejo, M.9
Platoshyn, O.10
Yuan, J.X.11
Masliah, E.12
-
33
-
-
35948979698
-
Neural stem cells improve memory in an inducible mouse model of neuronal loss
-
Yamasaki TR, Blurton-Jones M, Morrissette DA, Kitazawa M, Oddo S, LaFerla FM (2007) Neural stem cells improve memory in an inducible mouse model of neuronal loss. J Neurosci 27:11925-11933.
-
(2007)
J Neurosci
, vol.27
, pp. 11925-11933
-
-
Yamasaki, T.R.1
Blurton-Jones, M.2
Morrissette, D.A.3
Kitazawa, M.4
Oddo, S.5
LaFerla, F.M.6
-
34
-
-
0034685703
-
Casein kinase 1 delta mRNA is upregulated in Alzheimer disease brain
-
Yasojima K, Kuret J, DeMaggio AJ, McGeer E, McGeer PL (2000) Casein kinase 1 delta mRNA is upregulated in Alzheimer disease brain. Brain Res 865:116-120.
-
(2000)
Brain Res
, vol.865
, pp. 116-120
-
-
Yasojima, K.1
Kuret, J.2
DeMaggio, A.J.3
McGeer, E.4
McGeer, P.L.5
|