Antisense gene silencing: Therapy for neurodegenerative disorders?

Genes

Volumn 4, Issue 3, 2013, Pages 457-484

  Nielsen, Troels T ^a,b   Nielsen, Jørgen E ^a,b  

^a Rigshospitalet   (Denmark)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

CNS; Neurodegenerative disorders; RNA interference

Indexed keywords

HERPESVIRUS VECTOR; LENTIVIRUS VECTOR; MICRORNA; PARVOVIRUS VECTOR; RETROVIRUS VECTOR; SHORT HAIRPIN RNA; SMALL INTERFERING RNA; 4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID RECEPTOR; ADENOVIRUS VECTOR; ALPHA SYNUCLEIN; AMYLOID PRECURSOR PROTEIN; COPPER ZINC SUPEROXIDE DISMUTASE; DICER; DOPAMINE 1 RECEPTOR; DOPAMINE 2 RECEPTOR; DOUBLE STRANDED RNA; ENVELOPE PROTEIN; GLUTAMATE DECARBOXYLASE 67; LEUCINE RICH REPEAT KINASE 2; LIPOSOME; LOCKED NUCLEIC ACID; MACROGOL; MICROTUBULE ASSOCIATED PROTEIN; NANOPARTICLE; PEPTIDE NUCLEIC ACID; POLYGLUTAMINE; PRION PROTEIN; PROGRANULIN; VIRUS VECTOR;

ALZHEIMER DISEASE; AMYOTROPHIC LATERAL SCLEROSIS; ANTISENSE THERAPY; BIOGENESIS; DEGENERATIVE DISEASE; FRONTOTEMPORAL DEMENTIA; GENE SILENCING; GENE TECHNOLOGY; HUMAN; HUNTINGTON CHOREA; MONOGENIC DISORDER; MULTIPLE SCLEROSIS; NEUROPATHOLOGY; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; PARKINSON DISEASE; PRION DISEASE; REVIEW; RNA INTERFERENCE; SPINOCEREBELLAR DEGENERATION; VIRAL GENE DELIVERY SYSTEM; 3' UNTRANSLATED REGION; ALLELE; ARTICLE; CACNA1A GENE; CAG REPEAT; GENE; GENE EXPRESSION REGULATION; GENE FUNCTION; GENE MUTATION; GENE TARGETING; GENE TRANSFER; GENETIC DISORDER; LIPOSOMAL GENE DELIVERY SYSTEM; MOLECULAR RECOGNITION; MOLECULARLY TARGETED THERAPY; POLYGLUTAMINE DISORDER; PROMOTER REGION; PROTEIN AGGREGATION; PROTEIN EXPRESSION; PROTEIN FOLDING; PSEUDOTYPING; REPORTER GENE; RNA STRUCTURE; TRANSCRIPTION REGULATION; VIRUS GENOME;

EID: 84884158801     PISSN: None     EISSN: 20734425     Source Type: Journal    
DOI: 10.3390/genes4030457     Document Type: Review

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