Five siRNAs Targeting Three SNPs May Provide Therapy for Three-Quarters of Huntington's Disease Patients

Current Biology

Volumn 19, Issue 9, 2009, Pages 774-778

  Pfister, Edith L ^a   Kennington, Lori ^a   Straubhaar, Juerg ^a   Wagh, Sujata ^a   Liu, Wanzhou ^a   DiFiglia, Marian ^b   Landwehrmeyer, Bernhard ^c   Vonsattel, Jean Paul ^d   Zamore, Phillip D ^a   Aronin, Neil ^a  

^a UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

^c UNIVERSITY OF ULM   (Germany)

^d Columbia University School of Medicine ^*  (United States)

Author keywords

DNA; HUMDISEASE; RNA

Indexed keywords

HD PROTEIN, HUMAN; NERVE PROTEIN; NUCLEAR PROTEIN; SMALL INTERFERING RNA;

ARTICLE; DNA SEQUENCE; GENE THERAPY; GENETICS; HETEROZYGOTE DETECTION; HUMAN; HUNTINGTON CHOREA; METHODOLOGY; RNA INTERFERENCE; SINGLE NUCLEOTIDE POLYMORPHISM;

GENE THERAPY; HETEROZYGOTE DETECTION; HUMANS; HUNTINGTON DISEASE; NERVE TISSUE PROTEINS; NUCLEAR PROTEINS; POLYMORPHISM, SINGLE NUCLEOTIDE; RNA INTERFERENCE; RNA, SMALL INTERFERING; SEQUENCE ANALYSIS, DNA;

EID: 67349159137     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cub.2009.03.030     Document Type: Article

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