-
1
-
-
0034737298
-
RNAi: Double-stranded RNA directs the ATP-dependent cleavage of mRNA at 21 to 23 nucleotide intervals
-
Zamore,P.D., Tuschl,T., Sharp,P.A. and Bartel,D.P. (2000) RNAi: double-stranded RNA directs the ATP-dependent cleavage of mRNA at 21 to 23 nucleotide intervals. Cell, 101, 25-33.
-
(2000)
Cell
, vol.101
, pp. 25-33
-
-
Zamore, P.D.1
Tuschl, T.2
Sharp, P.A.3
Bartel, D.P.4
-
2
-
-
0035863097
-
RNA interference is mediated by 21- and 22-nucleotide RNAs
-
Elbashir,S.M., Lendeckel,W. and Tuschl,T. (2001) RNA interference is mediated by 21- and 22-nucleotide RNAs. Genes Dev., 15, 188-200.
-
(2001)
Genes Dev.
, vol.15
, pp. 188-200
-
-
Elbashir, S.M.1
Lendeckel, W.2
Tuschl, T.3
-
3
-
-
0035905766
-
Role for a bidentate ribonuclease in the initiation step of RNA interference
-
Bernstein,E., Caudy,A.A., Hammond,S.M. and Hannon,G.J. (2001) Role for a bidentate ribonuclease in the initiation step of RNA interference. Nature, 409, 363-366.
-
(2001)
Nature
, vol.409
, pp. 363-366
-
-
Bernstein, E.1
Caudy, A.A.2
Hammond, S.M.3
Hannon, G.J.4
-
4
-
-
8844271740
-
A protein sensor for siRNA asymmetry
-
Tomari,Y., Matranga,C., Haley,B., Martinez,N. and Zamore,P.D. (2004) A protein sensor for siRNA asymmetry. Science, 306, 1377-1380.
-
(2004)
Science
, vol.306
, pp. 1377-1380
-
-
Tomari, Y.1
Matranga, C.2
Haley, B.3
Martinez, N.4
Zamore, P.D.5
-
5
-
-
0141868916
-
R2D2, a bridge between the initiation and effector steps of the Drosophila RNAi pathway
-
Liu,Q., Rand,T.A., Kalidas,S., Du,F., Kim,H.-E., Smith,D.P. and Wang,X. (2003) R2D2, a bridge between the initiation and effector steps of the Drosophila RNAi pathway. Science, 301, 1921-1925.
-
(2003)
Science
, vol.301
, pp. 1921-1925
-
-
Liu, Q.1
Rand, T.A.2
Kalidas, S.3
Du, F.4
Kim, H.-E.5
Smith, D.P.6
Wang, X.7
-
6
-
-
4444368187
-
Argonaute2 is the catalytic engine of mammalian RNAi
-
Liu,J., Carmell,M.A., Rivas,F.V., Marsden,C.G., Thomson,J.M., Song,J.-J., Hammond,S.M., Joshua-Tor,L. and Hannon,G.J. (2004) Argonaute2 is the catalytic engine of mammalian RNAi. Science, 305, 1437-1441.
-
(2004)
Science
, vol.305
, pp. 1437-1441
-
-
Liu, J.1
Carmell, M.A.2
Rivas, F.V.3
Marsden, C.G.4
Thomson, J.M.5
Song, J.-J.6
Hammond, S.M.7
Joshua-Tor, L.8
Hannon, G.J.9
-
7
-
-
0034673638
-
An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells
-
Hammond,S.M., Bernstein,E., Beach,D. and Hannon,G.J. (2000) An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells. Nature, 404, 293-296.
-
(2000)
Nature
, vol.404
, pp. 293-296
-
-
Hammond, S.M.1
Bernstein, E.2
Beach, D.3
Hannon, G.J.4
-
8
-
-
0035942736
-
Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
-
Elbashir,S.M., Harborth,J., Lendeckel,W., Yalcin,A., Weber,K. and Tuschl,T. (2001) Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature, 411, 494-498.
-
(2001)
Nature
, vol.411
, pp. 494-498
-
-
Elbashir, S.M.1
Harborth, J.2
Lendeckel, W.3
Yalcin, A.4
Weber, K.5
Tuschl, T.6
-
9
-
-
0242669199
-
Coordinated histone modifications mediated by a CtBP co-repressor complex
-
Shi,Y., Sawada,J.-I., Sui,G., Aftar,E.B., Whetstine,J.R., Lan,F., Ogawa,H., Po-Shan Luke,M., Nakatani,Y. and Shi,Y. (2003) Coordinated histone modifications mediated by a CtBP co-repressor complex. Nature, 422, 735-738.
-
(2003)
Nature
, vol.422
, pp. 735-738
-
-
Shi, Y.1
Sawada, J.-I.2
Sui, G.3
Aftar, E.B.4
Whetstine, J.R.5
Lan, F.6
Ogawa, H.7
Po-Shan Luke, M.8
Nakatani, Y.9
Shi, Y.10
-
10
-
-
0037144546
-
A microRNA in a multiple-turnover RNAi enzyme complex
-
Hutvagner,G. and Zamore,P.D. (2002) A microRNA in a multiple-turnover RNAi enzyme complex. Science, 297, 2056-2060.
-
(2002)
Science
, vol.297
, pp. 2056-2060
-
-
Hutvagner, G.1
Zamore, P.D.2
-
11
-
-
0036787671
-
siRNA-mediated gene silencing in vitro and in vivo
-
Xia,H., Mao,Q., Paulson,H.L. and Davidson,B.L. (2002) siRNA-mediated gene silencing in vitro and in vivo. Nat. Biotechnol., 20, 1006-1010.
-
(2002)
Nat. Biotechnol.
, vol.20
, pp. 1006-1010
-
-
Xia, H.1
Mao, Q.2
Paulson, H.L.3
Davidson, B.L.4
-
12
-
-
0037452812
-
A general method for gene knockdown in mice by using lentiviral vectors expressing small interfering RNA
-
Tiscornia,G., Singer,O., Ikawa,M. and Verma,I.M. (2003) A general method for gene knockdown in mice by using lentiviral vectors expressing small interfering RNA. Proc. Natl Acad. Sci. USA, 100, 1844-1848.
-
(2003)
Proc. Natl Acad. Sci. USA
, vol.100
, pp. 1844-1848
-
-
Tiscornia, G.1
Singer, O.2
Ikawa, M.3
Verma, I.M.4
-
13
-
-
0037021437
-
Small interfering RNA and gene silencing in transgenic mice and rats
-
Hasuwa,H., Kaseda,K., Einarsdottir,T. and Okabe,M. (2002) Small interfering RNA and gene silencing in transgenic mice and rats. FEBS Lett., 532, 227-230.
-
(2002)
FEBS Lett.
, vol.532
, pp. 227-230
-
-
Hasuwa, H.1
Kaseda, K.2
Einarsdottir, T.3
Okabe, M.4
-
14
-
-
4043057946
-
RNAi suppresses polyglutamine-induced neurodegeneration in a model of spinocerebellar ataxia
-
Xia,H., Mao,Q., Eliason,S.L., Harper,S.Q., Martins,I.H., Orr,H.T., Paulson,H.L., Yang,L., Kotin,R.M. and Davidson,B.L. (2004) RNAi suppresses polyglutamine-induced neurodegeneration in a model of spinocerebellar ataxia. Nat. Med., 10, 816-820.
-
(2004)
Nat. Med.
, vol.10
, pp. 816-820
-
-
Xia, H.1
Mao, Q.2
Eliason, S.L.3
Harper, S.Q.4
Martins, I.H.5
Orr, H.T.6
Paulson, H.L.7
Yang, L.8
Kotin, R.M.9
Davidson, B.L.10
-
15
-
-
0037440160
-
Short hairpin type of dsRNAs that are controlled by tRNA(Val) promoter significantly induce RNAi-mediated gene silencing in the cytoplasm of human cells
-
Kawasaki,H. and Taira,K. (2003) Short hairpin type of dsRNAs that are controlled by tRNA(Val) promoter significantly induce RNAi-mediated gene silencing in the cytoplasm of human cells. Nucleic Acids Res., 31, 700-707.
-
(2003)
Nucleic Acids Res.
, vol.31
, pp. 700-707
-
-
Kawasaki, H.1
Taira, K.2
-
16
-
-
0038419800
-
Induction of an interferon response by RNAi vectors in mammalian cells
-
Bridge,A.J., Pebernard,S., Ducraux,A., Nicoulaz,A.L. and Iggo,R. (2003) Induction of an interferon response by RNAi vectors in mammalian cells. Nature Genet., 34, 263-264.
-
(2003)
Nature Genet.
, vol.34
, pp. 263-264
-
-
Bridge, A.J.1
Pebernard, S.2
Ducraux, A.3
Nicoulaz, A.L.4
Iggo, R.5
-
17
-
-
0037685280
-
Expression profiling reveals off-target gene regulation by RNAi
-
Jackson,A.L., Bartz,S.R., Schelter,J., Kobayashi,S.V., Burchard,J., Mao,M., Li,B., Cavet,G. and Linsley,P.S. (2003) Expression profiling reveals off-target gene regulation by RNAi. Nat. Biotechnol., 21, 635-637.
-
(2003)
Nat. Biotechnol.
, vol.21
, pp. 635-637
-
-
Jackson, A.L.1
Bartz, S.R.2
Schelter, J.3
Kobayashi, S.V.4
Burchard, J.5
Mao, M.6
Li, B.7
Cavet, G.8
Linsley, P.S.9
-
18
-
-
0037321349
-
New microRNAs from mouse and human
-
Lagos-Quintana,M., Rauhut,R., Meyer,J., Borkhardt,A. and Tuschl,T. (2003) New microRNAs from mouse and human. RNA, 9, 175-179.
-
(2003)
RNA
, vol.9
, pp. 175-179
-
-
Lagos-Quintana, M.1
Rauhut, R.2
Meyer, J.3
Borkhardt, A.4
Tuschl, T.5
-
19
-
-
8144225486
-
MicroRNA genes are transcribed by RNA polymerase II
-
Lee,Y., Kim,M., Han,J., Yeom,K.H., Lee,S., Baek,S.H. and Kim,V.N. (2004) MicroRNA genes are transcribed by RNA polymerase II. EMBO J., 23, 4051-4060.
-
(2004)
EMBO J.
, vol.23
, pp. 4051-4060
-
-
Lee, Y.1
Kim, M.2
Han, J.3
Yeom, K.H.4
Lee, S.5
Baek, S.H.6
Kim, V.N.7
-
20
-
-
0037273432
-
Sequence requirements for micro RNA processing and function in human cells
-
Zeng,Y. and Cullen,B.R. (2003) Sequence requirements for micro RNA processing and function in human cells. RNA, 9, 112-123.
-
(2003)
RNA
, vol.9
, pp. 112-123
-
-
Zeng, Y.1
Cullen, B.R.2
-
21
-
-
13644269779
-
Optimization of an siRNA-expression system with an improved hairpin and its significant suppressive effects in mammalian cells
-
Miyagishi,M., Sumimoto,H., Miyoshi,H., Kawakami,Y. and Taira,K. (2004) Optimization of an siRNA-expression system with an improved hairpin and its significant suppressive effects in mammalian cells. J. Gene Med., 6, 715-723.
-
(2004)
J. Gene Med.
, vol.6
, pp. 715-723
-
-
Miyagishi, M.1
Sumimoto, H.2
Miyoshi, H.3
Kawakami, Y.4
Taira, K.5
-
22
-
-
1542375910
-
Silencing of antiapoptotic survivin gene by multiple approaches of RNA interference technology
-
450-454
-
Ling,X. and Li,F. (2004) Silencing of antiapoptotic survivin gene by multiple approaches of RNA interference technology. Biotechniques, 36, 450-454, 456-460.
-
(2004)
Biotechniques
, vol.36
, pp. 456-460
-
-
Ling, X.1
Li, F.2
-
23
-
-
19444386359
-
Gene silencing in alveolar type II cells using cell-specific promoter in vitro and in vivo
-
Gou,D., Narasaraju,T., Chintagari,N.R., Jin,N., Wang,P. and Liu,L. (2004) Gene silencing in alveolar type II cells using cell-specific promoter in vitro and in vivo. Nucleic Acids Res., 32, e134.
-
(2004)
Nucleic Acids Res.
, vol.32
-
-
Gou, D.1
Narasaraju, T.2
Chintagari, N.R.3
Jin, N.4
Wang, P.5
Liu, L.6
-
24
-
-
0035955374
-
Identification of novel genes coding for small expressed RNAs
-
Lagos-Quintana,M., Rauhut,R., Lendeckel,W. and Tuschl,T. (2001) Identification of novel genes coding for small expressed RNAs. Science, 294, 853-858.
-
(2001)
Science
, vol.294
, pp. 853-858
-
-
Lagos-Quintana, M.1
Rauhut, R.2
Lendeckel, W.3
Tuschl, T.4
-
25
-
-
0242710159
-
Phenotype characteristics of transgenic male mice expressing human aromatase under ubiquitin C promoter
-
Li,X., Makela,S., Streng,T., Santti,R. and Poutanen,M. (2003) Phenotype characteristics of transgenic male mice expressing human aromatase under ubiquitin C promoter. J. Steroid Biochem. Mol. Biol., 86, 469-476.
-
(2003)
J. Steroid Biochem. Mol. Biol.
, vol.86
, pp. 469-476
-
-
Li, X.1
Makela, S.2
Streng, T.3
Santti, R.4
Poutanen, M.5
-
26
-
-
1542604807
-
An enhanced U6 promoter for synthesis of short hairpin RNA
-
Xia,X.G., Zhou,H., Ding,H., Affar el,B., Shi,Y. and Xu,Z. (2003) An enhanced U6 promoter for synthesis of short hairpin RNA. Nucleic Acids Res., 31, e100.
-
(2003)
Nucleic Acids Res.
, vol.31
-
-
Xia, X.G.1
Zhou, H.2
Ding, H.3
Affar el, B.4
Shi, Y.5
Xu, Z.6
-
27
-
-
0026465350
-
Neuroblastoma x spinal cord (NSC) hybrid cell lines resemble developing motor neurons
-
Cashman,N.R., Durham,H.D., Blusztajn,J.K., Oda,K., Tabira,T., Shaw,I.T., Dahrouge,S. and Antel,J.P. (1992) Neuroblastoma x spinal cord (NSC) hybrid cell lines resemble developing motor neurons. Dev. Dyn., 194, 209-221.
-
(1992)
Dev. Dyn.
, vol.194
, pp. 209-221
-
-
Cashman, N.R.1
Durham, H.D.2
Blusztajn, J.K.3
Oda, K.4
Tabira, T.5
Shaw, I.T.6
Dahrouge, S.7
Antel, J.P.8
-
28
-
-
0034775750
-
Specific double-stranded RNA interference in undifferentiated mouse embryonic stem cells
-
Yang,S., Tutton,S., Pierce,E. and Yoon,K. (2001) Specific double-stranded RNA interference in undifferentiated mouse embryonic stem cells. Mol. Cell. Biol., 21, 7807-7816.
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 7807-7816
-
-
Yang, S.1
Tutton, S.2
Pierce, E.3
Yoon, K.4
-
29
-
-
0036294527
-
Both natural and designed micro RNAs can inhibit the expression of cognate mRNAs when expressed in human cells
-
Zeng,Y., Wagner,E.J. and Cullen,B.R. (2002) Both natural and designed micro RNAs can inhibit the expression of cognate mRNAs when expressed in human cells. Mol. Cell, 9, 1327-1333.
-
(2002)
Mol. Cell
, vol.9
, pp. 1327-1333
-
-
Zeng, Y.1
Wagner, E.J.2
Cullen, B.R.3
-
30
-
-
0141843656
-
The nuclear RNase III Drosha initiates microRNA processing
-
Lee,Y., Ahn,C., Han,J., Choi,H., Kim,J., Yim,J., Lee,J., Provost,P., Radmark,O., Kim,S. et al. (2003) The nuclear RNase III Drosha initiates microRNA processing. Nature, 425, 415-419.
-
(2003)
Nature
, vol.425
, pp. 415-419
-
-
Lee, Y.1
Ahn, C.2
Han, J.3
Choi, H.4
Kim, J.5
Yim, J.6
Lee, J.7
Provost, P.8
Radmark, O.9
Kim, S.10
-
31
-
-
0037009364
-
MicroRNA maturation: Stepwise processing and subcellular localization
-
Lee,Y., Jeon,K., Lee,J.T., Kim,S. and Kim,V.N. (2002) MicroRNA maturation: Stepwise processing and subcellular localization. EMBO J., 21, 4663-4670.
-
(2002)
EMBO J.
, vol.21
, pp. 4663-4670
-
-
Lee, Y.1
Jeon, K.2
Lee, J.T.3
Kim, S.4
Kim, V.N.5
-
32
-
-
0036468677
-
Germline transmission and tissue-specific expression of transgenes delivered by lentiviral vectors
-
Lois,C., Hong,E.J., Pease,S., Brown,E.J. and Baltimore,D. (2002) Germline transmission and tissue-specific expression of transgenes delivered by lentiviral vectors. Science, 295, 868-872.
-
(2002)
Science
, vol.295
, pp. 868-872
-
-
Lois, C.1
Hong, E.J.2
Pease, S.3
Brown, E.J.4
Baltimore, D.5
-
33
-
-
0034922153
-
Effect of overexpression of wild-type and mutant Cu/Zn-superoxide dismutases on oxidative stress and cell death induced by hydrogen peroxide, 4-hydroxynonenal or serum deprivation: Potentiation of injury by ALS-related mutant superoxide dismutases and protection by Bcl-2
-
Lee,M., Hyun,D.-H., Halliwell,B. and Jenner,P. (2001) Effect of overexpression of wild-type and mutant Cu/Zn-superoxide dismutases on oxidative stress and cell death induced by hydrogen peroxide, 4-hydroxynonenal or serum deprivation: Potentiation of injury by ALS-related mutant superoxide dismutases and protection by Bcl-2. J. Neurochem., 78, 209-220.
-
(2001)
J. Neurochem.
, vol.78
, pp. 209-220
-
-
Lee, M.1
Hyun, D.-H.2
Halliwell, B.3
Jenner, P.4
|