Splice isoform-specific suppression of the Ca V2.1 variant underlying spinocerebellar ataxia type 6

Neurobiology of Disease

Volumn 43, Issue 3, 2011, Pages 533-542

  Tsou, Wei Ling ^a,b   Soong, Bing Wen ^a   Paulson, Henry L ^b   Rodríguez Lebrón, Edgardo ^b  

^a NATIONAL YANG MING UNIVERSITY   (Taiwan)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

Allele specific silencing; Alternative splicing; Autosomal dominant disorder; CACNA1A; Calcium channel; Cav2.1; Gene therapy; MicroRNA; Neurodegeneration; Polyglutamine; RNA interference; ShRNA; SiRNA; Spinocerebellar ataxia

Indexed keywords

ISOPROTEIN; MESSENGER RNA; MICRORNA; POLYGLUTAMINE; SODIUM CHANNEL CAV2.1; UNCLASSIFIED DRUG; VOLTAGE GATED CALCIUM CHANNEL;

ARTICLE; CELL LINE; CONTROLLED STUDY; DEGENERATIVE DISEASE; GENE DELIVERY SYSTEM; GENE REPRESSION; GENE SILENCING; HUMAN; HUMAN CELL; NERVE CELL; PRIORITY JOURNAL; REPORTER GENE; RNA INTERFERENCE; RNA PROCESSING; RNA SPLICING; SPINOCEREBELLAR ATAXIA TYPE 6; SPINOCEREBELLAR DEGENERATION; TRINUCLEOTIDE REPEAT;

ALTERNATIVE SPLICING; CALCIUM CHANNELS; CALCIUM CHANNELS, N-TYPE; CELL LINE, TUMOR; GENE THERAPY; GENETIC VARIATION; HUMANS; NEUROBLASTOMA; PROTEIN ISOFORMS; REPETITIVE SEQUENCES, NUCLEIC ACID; RNA SPLICING; RNA, MESSENGER; SPINOCEREBELLAR ATAXIAS; TRANSCRIPTION, GENETIC;

EID: 79960269997     PISSN: 09699961     EISSN: 1095953X     Source Type: Journal    
DOI: 10.1016/j.nbd.2011.04.016     Document Type: Article

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