-
1
-
-
14644426575
-
RNA silencing as a tool for exploring gene function in ascomycete fungi
-
Nakayashiki, H. et al. RNA silencing as a tool for exploring gene function in ascomycete fungi. Fungal Genet. Biol. 42, 275-283 (2005).
-
(2005)
Fungal Genet. Biol.
, vol.42
, pp. 275-283
-
-
Nakayashiki, H.1
-
2
-
-
4344698377
-
Using RNAi to improve plant nutritional value: From mechanism to application
-
Tang, G. & Galili, G. Using RNAi to improve plant nutritional value: from mechanism to application. Trends Biotechnol. 22, 463-469 (2004).
-
(2004)
Trends Biotechnol.
, vol.22
, pp. 463-469
-
-
Tang, G.1
Galili, G.2
-
3
-
-
9144272819
-
Using RNAi to catch Drosophila genes in a web of interactions: Insights into cancer research
-
Dasgupta, R. & Perrimon, N. Using RNAi to catch Drosophila genes in a web of interactions: insights into cancer research. Oncogene 23, 8359-8365 (2004).
-
(2004)
Oncogene
, vol.23
, pp. 8359-8365
-
-
Dasgupta, R.1
Perrimon, N.2
-
4
-
-
9144265089
-
Towards full employment: Using RNAi to find roles for the redundant
-
Fraser, A. Towards full employment: using RNAi to find roles for the redundant. Oncogene 23, 8346-8352 (2004).
-
(2004)
Oncogene
, vol.23
, pp. 8346-8352
-
-
Fraser, A.1
-
5
-
-
9144273425
-
RNA-interference-based functional genomics in mammalian cells: Reverse genetics coming of age
-
Silva, J., Chang, K., Hannon, G.J. & Rivas, F.V. RNA-interference- based functional genomics in mammalian cells: reverse genetics coming of age. Oncogene 23, 8401-8409 (2004).
-
(2004)
Oncogene
, vol.23
, pp. 8401-8409
-
-
Silva, J.1
Chang, K.2
Hannon, G.J.3
Rivas, F.V.4
-
6
-
-
0347444723
-
MicroRNAs: Genomics, biogenesis, mechanism, and function
-
Bartel, D.P. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 116, 281-297 (2004).
-
(2004)
Cell
, vol.116
, pp. 281-297
-
-
Bartel, D.P.1
-
7
-
-
3042767202
-
MicroRNAs: Small RNAs with a big role in gene regulation
-
He, L. & Hannon, G.J. MicroRNAs: small RNAs with a big role in gene regulation. Nat. Rev. Genet. 5, 522-531 (2004).
-
(2004)
Nat. Rev. Genet.
, vol.5
, pp. 522-531
-
-
He, L.1
Hannon, G.J.2
-
8
-
-
0034708122
-
The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans
-
Reinhart, B.J. et al. The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans. Nature 403, 901-906 (2000).
-
(2000)
Nature
, vol.403
, pp. 901-906
-
-
Reinhart, B.J.1
-
9
-
-
0035887005
-
Dicer functions in RNA interference and in synthesis of small RNA involved in developmental timing in C. elegans
-
Ketting, R.F. et al. Dicer functions in RNA interference and in synthesis of small RNA involved in developmental timing in C. elegans. Genes Dev. 15, 2654-2659 (2001).
-
(2001)
Genes Dev.
, vol.15
, pp. 2654-2659
-
-
Ketting, R.F.1
-
10
-
-
17844364875
-
Genes and mechanisms related to RNA interference regulate expression of the small temporal RNAs that control C. elegans developmental timing
-
Grishok, A. et al. Genes and mechanisms related to RNA interference regulate expression of the small temporal RNAs that control C. elegans developmental timing. Cell 106, 23-34 (2001).
-
(2001)
Cell
, vol.106
, pp. 23-34
-
-
Grishok, A.1
-
11
-
-
0035929322
-
A role for the RNase III enzyme DCR-1 in RNA interference and germ line development in Caenorhabditis elegans
-
Knight, S.W. & Bass, B.L. A role for the RNase III enzyme DCR-1 in RNA interference and germ line development in Caenorhabditis elegans. Science 293, 2269-2271 (2001).
-
(2001)
Science
, vol.293
, pp. 2269-2271
-
-
Knight, S.W.1
Bass, B.L.2
-
12
-
-
0035800521
-
A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA
-
Hutvagner, G. et al. A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA. Science 293, 834-838 (2001).
-
(2001)
Science
, vol.293
, pp. 834-838
-
-
Hutvagner, G.1
-
13
-
-
8144225486
-
MicroRNA genes are transcribed by RNA polymerase II
-
Lee, Y. et al. MicroRNA genes are transcribed by RNA polymerase II. EMBO J. 23, 4051-4060 (2004).
-
(2004)
EMBO J.
, vol.23
, pp. 4051-4060
-
-
Lee, Y.1
-
14
-
-
9344235449
-
Human microRNAs are processed from capped, polyadenylated transcripts that can also function as mRNAs
-
Cai, X., Hagedorn, C.H. & Cullen, B.R. Human microRNAs are processed from capped, polyadenylated transcripts that can also function as mRNAs. RNA 10, 1957-1966 (2004).
-
(2004)
RNA
, vol.10
, pp. 1957-1966
-
-
Cai, X.1
Hagedorn, C.H.2
Cullen, B.R.3
-
15
-
-
0141843656
-
The nuclear RNase III Drosha initiates microRNA processing
-
Lee, Y. et al. The nuclear RNase III Drosha initiates microRNA processing. Nature 425, 415-419 (2003).
-
(2003)
Nature
, vol.425
, pp. 415-419
-
-
Lee, Y.1
-
16
-
-
9144224451
-
Processing of primary microRNAs by the Microprocessor complex
-
Denli, A.M., Tops, B.B., Plasterk, R.H., Ketting, R.F. & Hannon, G.J. Processing of primary microRNAs by the Microprocessor complex. Nature 432, 231-235 (2004).
-
(2004)
Nature
, vol.432
, pp. 231-235
-
-
Denli, A.M.1
Tops, B.B.2
Plasterk, R.H.3
Ketting, R.F.4
Hannon, G.J.5
-
17
-
-
10344248903
-
The human DiGeorge syndrome critical region gene 8 and its D. melanogaster homolog are required for miRNA biogenesis
-
Landthaler, M., Yalcin, A. & Tuschl, T. The human DiGeorge syndrome critical region gene 8 and its D. melanogaster homolog are required for miRNA biogenesis. Curr. Biol. 14, 2162-2167 (2004).
-
(2004)
Curr. Biol.
, vol.14
, pp. 2162-2167
-
-
Landthaler, M.1
Yalcin, A.2
Tuschl, T.3
-
18
-
-
10644234841
-
The Drosha-DGCR8 complex in primary microRNA processing
-
Han, J. et al. The Drosha-DGCR8 complex in primary microRNA processing. Genes Dev. 18, 3016-3027 (2004).
-
(2004)
Genes Dev.
, vol.18
, pp. 3016-3027
-
-
Han, J.1
-
19
-
-
9144225636
-
The Microprocessor complex mediates the genesis of microRNAs
-
Gregory, R.I. et al. The Microprocessor complex mediates the genesis of microRNAs. Nature 432, 235-240 (2004).
-
(2004)
Nature
, vol.432
, pp. 235-240
-
-
Gregory, R.I.1
-
20
-
-
0347361541
-
Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs
-
Yi, R., Qin, Y., Macara, I.G. & Cullen, B.R. Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs. Genes Dev. 17, 3011-3016 (2003).
-
(2003)
Genes Dev.
, vol.17
, pp. 3011-3016
-
-
Yi, R.1
Qin, Y.2
Macara, I.G.3
Cullen, B.R.4
-
21
-
-
0347988235
-
Nuclear export of microRNA precursors
-
Lund, E., Guttinger, S., Calado, A., Dahlberg, J.E. & Kutay, U. Nuclear export of microRNA precursors. Science 303, 95-98 (2004).
-
(2004)
Science
, vol.303
, pp. 95-98
-
-
Lund, E.1
Guttinger, S.2
Calado, A.3
Dahlberg, J.E.4
Kutay, U.5
-
22
-
-
13844280638
-
Synthetic shRNAs as potent RNAi triggers
-
Siolas, D. et al. Synthetic shRNAs as potent RNAi triggers. Nat. Biotechnol. 23, 227-231 (2005).
-
(2005)
Nat. Biotechnol.
, vol.23
, pp. 227-231
-
-
Siolas, D.1
-
23
-
-
0345490960
-
The crystal structure of the Argonaute2 PAZ domain reveals an RNA binding motif in RNAi effector complexes
-
Song, J.J. et al. The crystal structure of the Argonaute2 PAZ domain reveals an RNA binding motif in RNAi effector complexes. Nat. Struct. Biol. 10, 1026-1032 (2003).
-
(2003)
Nat. Struct. Biol.
, vol.10
, pp. 1026-1032
-
-
Song, J.J.1
-
24
-
-
10744225153
-
Asymmetry in the assembly of the RNAi enzyme complex
-
Schwarz, D.S. et al. Asymmetry in the assembly of the RNAi enzyme complex. Cell 115, 199-208 (2003).
-
(2003)
Cell
, vol.115
, pp. 199-208
-
-
Schwarz, D.S.1
-
25
-
-
0142165224
-
Functional siRNAs and miRNAs exhibit strand bias
-
Khvorova, A., Reynolds, A. & Jayasena, S.D. Functional siRNAs and miRNAs exhibit strand bias. Cell 115, 209-216 (2003).
-
(2003)
Cell
, vol.115
, pp. 209-216
-
-
Khvorova, A.1
Reynolds, A.2
Jayasena, S.D.3
-
26
-
-
12144288006
-
A resource for large-scale RNA-interference-based screens in mammals
-
Paddison, P.J. et al. A resource for large-scale RNA-interference-based screens in mammals. Nature 428, 427-431 (2004).
-
(2004)
Nature
, vol.428
, pp. 427-431
-
-
Paddison, P.J.1
-
27
-
-
12144289681
-
A large-scale RNAi screen in human cells identifies new components of the p53 pathway
-
Berns, K. et al. A large-scale RNAi screen in human cells identifies new components of the p53 pathway. Nature 428, 431-437 (2004).
-
(2004)
Nature
, vol.428
, pp. 431-437
-
-
Berns, K.1
-
28
-
-
0036294527
-
Both natural and designed micro RNAs can inhibit the expression of cognate mRNAs when expressed in human cells
-
Zeng, Y., Wagner, E.J. & Cullen, B.R. Both natural and designed micro RNAs can inhibit the expression of cognate mRNAs when expressed in human cells. Mol. Cell 9, 1327-1333 (2002).
-
(2002)
Mol. Cell
, vol.9
, pp. 1327-1333
-
-
Zeng, Y.1
Wagner, E.J.2
Cullen, B.R.3
-
29
-
-
0037089589
-
Short hairpin RNAs (shRNAs) induce sequence-specific silencing in mammalian cells
-
Paddison, P.J., Caudy, A.A., Bernstein, E., Hannon, G.J. & Conklin, D.S. Short hairpin RNAs (shRNAs) induce sequence-specific silencing in mammalian cells. Genes Dev. 16, 948-958 (2002).
-
(2002)
Genes Dev.
, vol.16
, pp. 948-958
-
-
Paddison, P.J.1
Caudy, A.A.2
Bernstein, E.3
Hannon, G.J.4
Conklin, D.S.5
-
30
-
-
20444376939
-
A genetic screen for candidate tumor suppressors identifies REST
-
Westbrook, T.F. et al. A genetic screen for candidate tumor suppressors identifies REST. Cell 121, 837-848 (2005).
-
(2005)
Cell
, vol.121
, pp. 837-848
-
-
Westbrook, T.F.1
-
31
-
-
0346727524
-
MicroRNAs modulate hematopoietic lineage differentiation
-
Chen, C.Z., Li, L., Lodish, H.F. & Bartel, D.P. MicroRNAs modulate hematopoietic lineage differentiation. Science 303, 83-86 (2004).
-
(2004)
Science
, vol.303
, pp. 83-86
-
-
Chen, C.Z.1
Li, L.2
Lodish, H.F.3
Bartel, D.P.4
-
32
-
-
0037273432
-
Sequence requirements for micro RNA processing and function in human cells
-
Zeng, Y. & Cullen, B.R. Sequence requirements for micro RNA processing and function in human cells. RNA 9, 112-123 (2003).
-
(2003)
RNA
, vol.9
, pp. 112-123
-
-
Zeng, Y.1
Cullen, B.R.2
-
33
-
-
0037440160
-
Short hairpin type of dsRNAs that are controlled by tRNA(Val) promoter significantly induce RNAi-mediated gene silencing in the cytoplasm of human cells
-
Kawasaki, H. & Taira, K. Short hairpin type of dsRNAs that are controlled by tRNA(Val) promoter significantly induce RNAi-mediated gene silencing in the cytoplasm of human cells. Nucleic Acids Res. 31, 700-707 (2003).
-
(2003)
Nucleic Acids Res.
, vol.31
, pp. 700-707
-
-
Kawasaki, H.1
Taira, K.2
-
34
-
-
0037134020
-
A system for stable expression of short interfering RNAs in mammalian cells
-
Brummelkamp, T.R., Bernards, R. & Agami, R. A system for stable expression of short interfering RNAs in mammalian cells. Science 296, 550-553 (2002).
-
(2002)
Science
, vol.296
, pp. 550-553
-
-
Brummelkamp, T.R.1
Bernards, R.2
Agami, R.3
-
35
-
-
0347089019
-
An approach to genomewide screens of expressed small interfering RNAs in mammalian cells
-
Zheng, L. et al. An approach to genomewide screens of expressed small interfering RNAs in mammalian cells. Proc. Natl. Acad. Sci. USA 101, 135-140 (2004).
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 135-140
-
-
Zheng, L.1
-
36
-
-
27644582893
-
Probing tumor phenotypes using stable and regulated synthetic microRNA precursors
-
advance online publication 2 October (doi:10.1038/ng1651)
-
Dickins, R.A. et al. Probing tumor phenotypes using stable and regulated synthetic microRNA precursors. Nat. Genet., advance online publication 2 October 2005 (doi:10.1038/ng1651).
-
(2005)
Nat. Genet.
-
-
Dickins, R.A.1
-
37
-
-
24944560377
-
A lentiviral microRNA-based system for single copy Pol II regulated RNAi in mammalian cells
-
Stegmeier, F., Hu, G., Rickles, R.J., Hannon, G.J. & Elledge, S.J. A lentiviral microRNA-based system for single copy Pol II regulated RNAi in mammalian cells. Proc. Natl. Acad. Sci. USA 102, 13212-13217 (2005).
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 13212-13217
-
-
Stegmeier, F.1
Hu, G.2
Rickles, R.J.3
Hannon, G.J.4
Elledge, S.J.5
-
38
-
-
15044348273
-
MAGIC, an in vivo genetic method for the rapid construction of recombinant DNA molecules
-
Li, M.Z. & Elledge, S.J. MAGIC, an in vivo genetic method for the rapid construction of recombinant DNA molecules. Nat. Genet. 37, 311-319 (2005).
-
(2005)
Nat. Genet.
, vol.37
, pp. 311-319
-
-
Li, M.Z.1
Elledge, S.J.2
-
39
-
-
20844438492
-
Production of complex nucleic acid libraries using highly parallel in situ oligonucleotide synthesis
-
Cleary, M.A. et al. Production of complex nucleic acid libraries using highly parallel in situ oligonucleotide synthesis. Nat. Methods 1, 241-248 (2004).
-
(2004)
Nat. Methods
, vol.1
, pp. 241-248
-
-
Cleary, M.A.1
-
40
-
-
0032567339
-
Generation of destabilized green fluorescent protein as a transcription reporter
-
Li, X. et al. Generation of destabilized green fluorescent protein as a transcription reporter. J. Biol. Chem. 273, 34970-34975 (1998).
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 34970-34975
-
-
Li, X.1
-
41
-
-
1442360415
-
RNase III enzymes and the initiation of gene silencing
-
Carmell, M.A. & Hannon, G.J. RNase III enzymes and the initiation of gene silencing. Nat. Struct. Mol. Biol. 11, 214-218 (2004).
-
(2004)
Nat. Struct. Mol. Biol.
, vol.11
, pp. 214-218
-
-
Carmell, M.A.1
Hannon, G.J.2
-
42
-
-
0021833274
-
Phasmid vectors for identification of genes by complementation of Escherichia coli mutants
-
Elledge, S.J. & Walker, G.C. Phasmid vectors for identification of genes by complementation of Escherichia coli mutants. J. Bacteriol. 162, 777-783 (1985).
-
(1985)
J. Bacteriol.
, vol.162
, pp. 777-783
-
-
Elledge, S.J.1
Walker, G.C.2
-
43
-
-
0034612342
-
One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products
-
Datsenko, K.A. & Wanner, B.L. One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products. Proc. Natl. Acad. Sci. USA 97, 6640-6645 (2000).
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 6640-6645
-
-
Datsenko, K.A.1
Wanner, B.L.2
-
44
-
-
0029065955
-
Gene disruption in Escherichia coli: TcR and KmR cassettes with the option of Flp-catalyzed excision of the antibiotic-resistance determinant
-
Cherepanov, P.P. & Wackernagel, W. Gene disruption in Escherichia coli: TcR and KmR cassettes with the option of Flp-catalyzed excision of the antibiotic-resistance determinant. Gene 158, 9-14 (1995).
-
(1995)
Gene
, vol.158
, pp. 9-14
-
-
Cherepanov, P.P.1
Wackernagel, W.2
-
45
-
-
0024242990
-
Escherichia coli sbcC mutants permit stable propagation of DNA replicons containing a long palindrome
-
Chalker, A.F., Leach, D.R. & Lloyd, R.G. Escherichia coli sbcC mutants permit stable propagation of DNA replicons containing a long palindrome. Gene 71, 201-205 (1988).
-
(1988)
Gene
, vol.71
, pp. 201-205
-
-
Chalker, A.F.1
Leach, D.R.2
Lloyd, R.G.3
-
46
-
-
0036792769
-
Fragile X-related protein and VIG associate with the RNA interference machinery
-
Caudy, A.A., Myers, M., Hannon, G.J. & Hammond, S.M. Fragile X-related protein and VIG associate with the RNA interference machinery. Genes Dev. 16, 2491-2496 (2002).
-
(2002)
Genes Dev.
, vol.16
, pp. 2491-2496
-
-
Caudy, A.A.1
Myers, M.2
Hannon, G.J.3
Hammond, S.M.4
|