메뉴 건너뛰기




Volumn 102, Issue 2, 2013, Pages 84-95

Genomic aspects of NAFLD pathogenesis

Author keywords

Candidate gene approaches; Genomics; GWAS; Hepatocellular carcinoma; NASH; Non alcoholic fatty liver disease

Indexed keywords

ADIPONECTIN; APOLIPOPROTEIN C3; APOLIPOPROTEIN E; BINDING PROTEIN; CARBOHYDRATE RESPONSE ELEMENT BINDING PROTEIN; DRUG METABOLIZING ENZYME; GLUTATHIONE TRANSFERASE; GROWTH HORMONE; INSULIN RECEPTOR; INTERLEUKIN 6; LYSOPHOSPHOLIPASE; MANGANESE SUPEROXIDE DISMUTASE; MICROSOMAL TRIGLYCERIDE TRANSFER PROTEIN; NEUROCAN; PATATIN LIKE PHOSPHOLIPASE DOMAIN CONTAINING 3; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PHOSPHATIDYLETHANOLAMINE METHYLTRANSFERASE; SOMATOMEDIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

EID: 84880953100     PISSN: 08887543     EISSN: 10898646     Source Type: Journal    
DOI: 10.1016/j.ygeno.2013.03.007     Document Type: Review
Times cited : (82)

References (168)
  • 1
    • 57749183469 scopus 로고    scopus 로고
    • Prevalence and associated factors of non-alcoholic fatty liver disease in patients with type-2 diabetes mellitus
    • Leite N.C., Salles G.F., Araujo A.L., Villela-Nogueira C.A., Cardoso C.R. Prevalence and associated factors of non-alcoholic fatty liver disease in patients with type-2 diabetes mellitus. Liver Int. 2009, 29:113-119.
    • (2009) Liver Int. , vol.29 , pp. 113-119
    • Leite, N.C.1    Salles, G.F.2    Araujo, A.L.3    Villela-Nogueira, C.A.4    Cardoso, C.R.5
  • 2
    • 33748110788 scopus 로고    scopus 로고
    • Hepatic histology in obese patients undergoing bariatric surgery
    • Machado M., Marques-Vidal P., Cortez-Pinto H. Hepatic histology in obese patients undergoing bariatric surgery. J. Hepatol. 2006, 45:600-606.
    • (2006) J. Hepatol. , vol.45 , pp. 600-606
    • Machado, M.1    Marques-Vidal, P.2    Cortez-Pinto, H.3
  • 3
    • 84861543083 scopus 로고    scopus 로고
    • The diagnosis and management of non-alcoholic fatty liver disease: practice Guideline by the American Association for the Study of Liver Diseases, American College of Gastroenterology, and the American Gastroenterological Association
    • Chalasani N., Younossi Z., Lavine J.E., Diehl A.M., Brunt E.M., Cusi K., Charlton M., Sanyal A.J. The diagnosis and management of non-alcoholic fatty liver disease: practice Guideline by the American Association for the Study of Liver Diseases, American College of Gastroenterology, and the American Gastroenterological Association. Hepatology 2012, 55:2005-2023.
    • (2012) Hepatology , vol.55 , pp. 2005-2023
    • Chalasani, N.1    Younossi, Z.2    Lavine, J.E.3    Diehl, A.M.4    Brunt, E.M.5    Cusi, K.6    Charlton, M.7    Sanyal, A.J.8
  • 4
    • 84861197159 scopus 로고    scopus 로고
    • Hepatocellular carcinoma in non-alcoholic fatty liver disease: an emerging menace
    • Baffy G., Brunt E.M., Caldwell S.H. Hepatocellular carcinoma in non-alcoholic fatty liver disease: an emerging menace. J. Hepatol. 2012, 56:1384-1391.
    • (2012) J. Hepatol. , vol.56 , pp. 1384-1391
    • Baffy, G.1    Brunt, E.M.2    Caldwell, S.H.3
  • 6
    • 80053088189 scopus 로고    scopus 로고
    • Hepatocellular carcinoma
    • El-Serag H.B. Hepatocellular carcinoma. N. Engl. J. Med. 2011, 365:1118-1127.
    • (2011) N. Engl. J. Med. , vol.365 , pp. 1118-1127
    • El-Serag, H.B.1
  • 8
    • 34948867745 scopus 로고    scopus 로고
    • Overweight, obesity and risk of liver cancer: a meta-analysis of cohort studies
    • Larsson S.C., Wolk A. Overweight, obesity and risk of liver cancer: a meta-analysis of cohort studies. Br. J. Cancer 2007, 97:1005-1008.
    • (2007) Br. J. Cancer , vol.97 , pp. 1005-1008
    • Larsson, S.C.1    Wolk, A.2
  • 11
    • 81855180303 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease: focus on lipoprotein and lipid deregulation
    • Fon Tacer K., Rozman D. Nonalcoholic fatty liver disease: focus on lipoprotein and lipid deregulation. J. Lipids 2011, 2011.
    • (2011) J. Lipids , vol.2011
    • Fon Tacer, K.1    Rozman, D.2
  • 12
    • 84876097108 scopus 로고    scopus 로고
    • Cholesterol and Inflammation at the Crossroads of Non-alcoholic Fatty Liver Disease (NAFLD) and Atherogenesis
    • S. Parthasarathy (Ed.)
    • Lorbek G., Rozman D. Cholesterol and Inflammation at the Crossroads of Non-alcoholic Fatty Liver Disease (NAFLD) and Atherogenesis. Atherogenesis, InTech 2012, 281-304. S. Parthasarathy (Ed.).
    • (2012) Atherogenesis, InTech , pp. 281-304
    • Lorbek, G.1    Rozman, D.2
  • 13
    • 78649433367 scopus 로고    scopus 로고
    • Histopathology of nonalcoholic fatty liver disease
    • Brunt E.M., Tiniakos D.G. Histopathology of nonalcoholic fatty liver disease. World J. Gastroenterol. 2010, 16:5286-5296.
    • (2010) World J. Gastroenterol. , vol.16 , pp. 5286-5296
    • Brunt, E.M.1    Tiniakos, D.G.2
  • 14
    • 1942454793 scopus 로고    scopus 로고
    • Nonalcoholic steatohepatitis
    • Brunt E.M. Nonalcoholic steatohepatitis. Semin. Liver Dis. 2004, 24:3-20.
    • (2004) Semin. Liver Dis. , vol.24 , pp. 3-20
    • Brunt, E.M.1
  • 15
    • 18244382304 scopus 로고    scopus 로고
    • Sources of fatty acids stored in liver and secreted via lipoproteins in patients with nonalcoholic fatty liver disease
    • Donnelly K.L., Smith C.I., Schwarzenberg S.J., Jessurun J., Boldt M.D., Parks E.J. Sources of fatty acids stored in liver and secreted via lipoproteins in patients with nonalcoholic fatty liver disease. J. Clin. Invest. 2005, 115:1343-1351.
    • (2005) J. Clin. Invest. , vol.115 , pp. 1343-1351
    • Donnelly, K.L.1    Smith, C.I.2    Schwarzenberg, S.J.3    Jessurun, J.4    Boldt, M.D.5    Parks, E.J.6
  • 17
    • 78649475438 scopus 로고    scopus 로고
    • Effects of nuclear receptor FXR on the regulation of liver lipid metabolism in patients with non-alcoholic fatty liver disease
    • Yang Z.X., Shen W., Sun H. Effects of nuclear receptor FXR on the regulation of liver lipid metabolism in patients with non-alcoholic fatty liver disease. Hepatol. Int. 2010, 4:741-748.
    • (2010) Hepatol. Int. , vol.4 , pp. 741-748
    • Yang, Z.X.1    Shen, W.2    Sun, H.3
  • 18
  • 19
    • 39849099238 scopus 로고    scopus 로고
    • Role of peroxisome proliferators-activated receptors in the pathogenesis and treatment of nonalcoholic fatty liver disease
    • Kallwitz E.R., McLachlan A., Cotler S.J. Role of peroxisome proliferators-activated receptors in the pathogenesis and treatment of nonalcoholic fatty liver disease. World J. Gastroenterol. 2008, 14:22-28.
    • (2008) World J. Gastroenterol. , vol.14 , pp. 22-28
    • Kallwitz, E.R.1    McLachlan, A.2    Cotler, S.J.3
  • 20
    • 84875218268 scopus 로고    scopus 로고
    • Molecular interactions between NAFLD and xenobiotic metabolism
    • Naik A., Belič A., Zanger U.M., Rozman D. Molecular interactions between NAFLD and xenobiotic metabolism. Front. Genet. 2013, 4:2.
    • (2013) Front. Genet. , vol.4 , pp. 2
    • Naik, A.1    Belič, A.2    Zanger, U.M.3    Rozman, D.4
  • 21
    • 0031947715 scopus 로고    scopus 로고
    • Steatohepatitis: a tale of two "hits"?
    • Day C.P., James O.F. Steatohepatitis: a tale of two "hits"?. Gastroenterology 1998, 114:842-845.
    • (1998) Gastroenterology , vol.114 , pp. 842-845
    • Day, C.P.1    James, O.F.2
  • 22
    • 30044431801 scopus 로고    scopus 로고
    • From fat to inflammation
    • Day C.P. From fat to inflammation. Gastroenterology 2006, 130:207-210.
    • (2006) Gastroenterology , vol.130 , pp. 207-210
    • Day, C.P.1
  • 24
    • 34250356015 scopus 로고    scopus 로고
    • Inhibiting triglyceride synthesis improves hepatic steatosis but exacerbates liver damage and fibrosis in obese mice with nonalcoholic steatohepatitis
    • Yamaguchi K., Yang L., McCall S., Huang J., Yu X.X., Pandey S.K., Bhanot S., Monia B.P., Li Y.X., Diehl A.M. Inhibiting triglyceride synthesis improves hepatic steatosis but exacerbates liver damage and fibrosis in obese mice with nonalcoholic steatohepatitis. Hepatology 2007, 45:1366-1374.
    • (2007) Hepatology , vol.45 , pp. 1366-1374
    • Yamaguchi, K.1    Yang, L.2    McCall, S.3    Huang, J.4    Yu, X.X.5    Pandey, S.K.6    Bhanot, S.7    Monia, B.P.8    Li, Y.X.9    Diehl, A.M.10
  • 25
    • 54049150442 scopus 로고    scopus 로고
    • Molecular mechanisms and therapeutic targets in steatosis and steatohepatitis
    • Anderson N., Borlak J. Molecular mechanisms and therapeutic targets in steatosis and steatohepatitis. Pharmacol. Rev. 2008, 60:311-357.
    • (2008) Pharmacol. Rev. , vol.60 , pp. 311-357
    • Anderson, N.1    Borlak, J.2
  • 29
    • 33845575826 scopus 로고    scopus 로고
    • Disruption of endoplasmic reticulum structure and integrity in lipotoxic cell death
    • Borradaile N.M., Han X., Harp J.D., Gale S.E., Ory D.S., Schaffer J.E. Disruption of endoplasmic reticulum structure and integrity in lipotoxic cell death. J. Lipid Res. 2006, 47:2726-2737.
    • (2006) J. Lipid Res. , vol.47 , pp. 2726-2737
    • Borradaile, N.M.1    Han, X.2    Harp, J.D.3    Gale, S.E.4    Ory, D.S.5    Schaffer, J.E.6
  • 39
    • 70349238777 scopus 로고    scopus 로고
    • Adipokines in liver diseases
    • Marra F., Bertolani C. Adipokines in liver diseases. Hepatology 2009, 50:957-969.
    • (2009) Hepatology , vol.50 , pp. 957-969
    • Marra, F.1    Bertolani, C.2
  • 41
    • 33748111665 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease: cytokine-adipokine interplay and regulation of insulin resistance
    • Tilg H., Hotamisligil G.S. Nonalcoholic fatty liver disease: cytokine-adipokine interplay and regulation of insulin resistance. Gastroenterology 2006, 131:934-945.
    • (2006) Gastroenterology , vol.131 , pp. 934-945
    • Tilg, H.1    Hotamisligil, G.S.2
  • 42
    • 77958546532 scopus 로고    scopus 로고
    • Obesity affects the liver - the link between adipocytes and hepatocytes
    • Wree A., Kahraman A., Gerken G., Canbay A. Obesity affects the liver - the link between adipocytes and hepatocytes. Digestion 2011, 83:124-133.
    • (2011) Digestion , vol.83 , pp. 124-133
    • Wree, A.1    Kahraman, A.2    Gerken, G.3    Canbay, A.4
  • 43
    • 56649083495 scopus 로고    scopus 로고
    • Mechanisms of disease progression in nonalcoholic fatty liver disease
    • Jou J., Choi S.S., Diehl A.M. Mechanisms of disease progression in nonalcoholic fatty liver disease. Semin. Liver Dis. 2008, 28:370,379.
    • (2008) Semin. Liver Dis. , vol.28 , pp. 370-379
    • Jou, J.1    Choi, S.S.2    Diehl, A.M.3
  • 44
    • 1642355723 scopus 로고    scopus 로고
    • The spectrum expanded: cryptogenic cirrhosis and the natural history of non-alcoholic fatty liver disease
    • Caldwell S.H., Crespo D.M. The spectrum expanded: cryptogenic cirrhosis and the natural history of non-alcoholic fatty liver disease. J. Hepatol. 2004, 40:578-584.
    • (2004) J. Hepatol. , vol.40 , pp. 578-584
    • Caldwell, S.H.1    Crespo, D.M.2
  • 46
    • 0035392939 scopus 로고    scopus 로고
    • Hepatic hyperplasia in noncirrhotic fatty livers: is obesity-related hepatic steatosis a premalignant condition?
    • Yang S., Lin H.Z., Hwang J., Chacko V.P., Diehl A.M. Hepatic hyperplasia in noncirrhotic fatty livers: is obesity-related hepatic steatosis a premalignant condition?. Cancer Res. 2001, 61:5016-5023.
    • (2001) Cancer Res. , vol.61 , pp. 5016-5023
    • Yang, S.1    Lin, H.Z.2    Hwang, J.3    Chacko, V.P.4    Diehl, A.M.5
  • 47
    • 77957200500 scopus 로고    scopus 로고
    • Non-alcoholic fatty liver disease as a risk factor for hepatocellular carcinoma: mechanisms and implications
    • Stickel F., Hellerbrand C. Non-alcoholic fatty liver disease as a risk factor for hepatocellular carcinoma: mechanisms and implications. Gut 2010, 59:1303-1307.
    • (2010) Gut , vol.59 , pp. 1303-1307
    • Stickel, F.1    Hellerbrand, C.2
  • 48
    • 67349210047 scopus 로고    scopus 로고
    • Unsaturated fatty acids promote hepatoma proliferation and progression through downregulation of the tumor suppressor PTEN
    • Vinciguerra M., Carrozzino F., Peyrou M., Carlone S., Montesano R., Benelli R., Foti M. Unsaturated fatty acids promote hepatoma proliferation and progression through downregulation of the tumor suppressor PTEN. J. Hepatol. 2009, 50:1132-1141.
    • (2009) J. Hepatol. , vol.50 , pp. 1132-1141
    • Vinciguerra, M.1    Carrozzino, F.2    Peyrou, M.3    Carlone, S.4    Montesano, R.5    Benelli, R.6    Foti, M.7
  • 49
    • 33745828301 scopus 로고    scopus 로고
    • Saturated fatty acids induce endoplasmic reticulum stress and apoptosis independently of ceramide in liver cells
    • Wei Y., Wang D., Topczewski F., Pagliassotti M.J. Saturated fatty acids induce endoplasmic reticulum stress and apoptosis independently of ceramide in liver cells. Am. J. Physiol. Endocrinol. Metab. 2006, 291:E275-E281.
    • (2006) Am. J. Physiol. Endocrinol. Metab. , vol.291
    • Wei, Y.1    Wang, D.2    Topczewski, F.3    Pagliassotti, M.J.4
  • 51
    • 77950625001 scopus 로고    scopus 로고
    • Functional proteomic analysis of nonalcoholic fatty liver disease in rat models: enoyl-coenzyme a hydratase down-regulation exacerbates hepatic steatosis
    • Zhang X., Yang J., Guo Y., Ye H., Yu C., Xu C., Xu L., Wu S., Sun W., Wei H., Gao X., Zhu Y., Qian X., Jiang Y., Li Y., He F. Functional proteomic analysis of nonalcoholic fatty liver disease in rat models: enoyl-coenzyme a hydratase down-regulation exacerbates hepatic steatosis. Hepatology 2010, 51:1190-1199.
    • (2010) Hepatology , vol.51 , pp. 1190-1199
    • Zhang, X.1    Yang, J.2    Guo, Y.3    Ye, H.4    Yu, C.5    Xu, C.6    Xu, L.7    Wu, S.8    Sun, W.9    Wei, H.10    Gao, X.11    Zhu, Y.12    Qian, X.13    Jiang, Y.14    Li, Y.15    He, F.16
  • 52
    • 34547488563 scopus 로고    scopus 로고
    • A systems biology approach to the pathogenesis of obesity-related nonalcoholic fatty liver disease using reverse phase protein microarrays for multiplexed cell signaling analysis
    • Calvert V.S., Collantes R., Elariny H., Afendy A., Baranova A., Mendoza M., Goodman Z., Liotta L.A., Petricoin E.F., Younossi Z.M. A systems biology approach to the pathogenesis of obesity-related nonalcoholic fatty liver disease using reverse phase protein microarrays for multiplexed cell signaling analysis. Hepatology 2007, 46:166-172.
    • (2007) Hepatology , vol.46 , pp. 166-172
    • Calvert, V.S.1    Collantes, R.2    Elariny, H.3    Afendy, A.4    Baranova, A.5    Mendoza, M.6    Goodman, Z.7    Liotta, L.A.8    Petricoin, E.F.9    Younossi, Z.M.10
  • 56
    • 77953287827 scopus 로고    scopus 로고
    • Hepatic gene expression of Caucasian and African-American patients with obesity-related non-alcoholic fatty liver disease
    • Stepanova M., Hossain N., Afendy A., Perry K., Goodman Z.D., Baranova A., Younossi Z. Hepatic gene expression of Caucasian and African-American patients with obesity-related non-alcoholic fatty liver disease. Obes. Surg. 2010, 20:640-650.
    • (2010) Obes. Surg. , vol.20 , pp. 640-650
    • Stepanova, M.1    Hossain, N.2    Afendy, A.3    Perry, K.4    Goodman, Z.D.5    Baranova, A.6    Younossi, Z.7
  • 59
    • 84873909398 scopus 로고    scopus 로고
    • Genetic and epigenetic variants influencing the development of nonalcoholic fatty liver disease
    • Li Y.Y. Genetic and epigenetic variants influencing the development of nonalcoholic fatty liver disease. World J. Gastroenterol. 2012, 18:6546-6551.
    • (2012) World J. Gastroenterol. , vol.18 , pp. 6546-6551
    • Li, Y.Y.1
  • 60
    • 84865127217 scopus 로고    scopus 로고
    • Single nucleotide polymorphisms and risk of hepatocellular carcinoma in cirrhosis
    • Nahon P., Zucman-Rossi J. Single nucleotide polymorphisms and risk of hepatocellular carcinoma in cirrhosis. J. Hepatol. 2012, 57:663-674.
    • (2012) J. Hepatol. , vol.57 , pp. 663-674
    • Nahon, P.1    Zucman-Rossi, J.2
  • 61
    • 84857947511 scopus 로고    scopus 로고
    • Nonalcoholic steatohepatitis and noncirrhotic hepatocellular carcinoma: fertile soil
    • Torres D.M., Harrison S.A. Nonalcoholic steatohepatitis and noncirrhotic hepatocellular carcinoma: fertile soil. Semin. Liver Dis. 2012, 32:30-38.
    • (2012) Semin. Liver Dis. , vol.32 , pp. 30-38
    • Torres, D.M.1    Harrison, S.A.2
  • 69
    • 84862765487 scopus 로고    scopus 로고
    • A multi-ethnic study of a PNPLA3 gene variant and its association with disease severity in non-alcoholic fatty liver disease
    • Zain S.M., Mohamed R., Mahadeva S., Cheah P.L., Rampal S., Basu R.C., Mohamed Z. A multi-ethnic study of a PNPLA3 gene variant and its association with disease severity in non-alcoholic fatty liver disease. Hum. Genet. 2012, 131(7):1145-1152.
    • (2012) Hum. Genet. , vol.131 , Issue.7 , pp. 1145-1152
    • Zain, S.M.1    Mohamed, R.2    Mahadeva, S.3    Cheah, P.L.4    Rampal, S.5    Basu, R.C.6    Mohamed, Z.7
  • 75
    • 0037644804 scopus 로고    scopus 로고
    • Biological functions of tumor necrosis factor cytokines and their receptors
    • Pfeffer K. Biological functions of tumor necrosis factor cytokines and their receptors. Cytokine Growth Factor Rev. 2003, 14:185-191.
    • (2003) Cytokine Growth Factor Rev. , vol.14 , pp. 185-191
    • Pfeffer, K.1
  • 76
    • 39149143637 scopus 로고    scopus 로고
    • Adipokines: the missing link between insulin resistance and obesity
    • Antuna-Puente B., Feve B., Fellahi S., Bastard J.P. Adipokines: the missing link between insulin resistance and obesity. Diabetes Metab. 2008, 34:2-11.
    • (2008) Diabetes Metab. , vol.34 , pp. 2-11
    • Antuna-Puente, B.1    Feve, B.2    Fellahi, S.3    Bastard, J.P.4
  • 77
    • 81255176365 scopus 로고    scopus 로고
    • Tumour necrosis factor gene polymorphism and disease prevalence
    • Qidwai T., Khan F. Tumour necrosis factor gene polymorphism and disease prevalence. Scand. J. Immunol. 2011, 74:522-547.
    • (2011) Scand. J. Immunol. , vol.74 , pp. 522-547
    • Qidwai, T.1    Khan, F.2
  • 81
    • 67650792743 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha gene promoter polymorphisms in Chinese patients with nonalcoholic fatty liver diseases
    • Hu Z.W., Luo H.B., Xu Y.M., Guo J.W., Deng X.L., Tong Y.W., Tang X. Tumor necrosis factor-alpha gene promoter polymorphisms in Chinese patients with nonalcoholic fatty liver diseases. Acta Gastroenterol Belg 2009, 72:215-221.
    • (2009) Acta Gastroenterol Belg , vol.72 , pp. 215-221
    • Hu, Z.W.1    Luo, H.B.2    Xu, Y.M.3    Guo, J.W.4    Deng, X.L.5    Tong, Y.W.6    Tang, X.7
  • 84
    • 84863377228 scopus 로고    scopus 로고
    • Association of tumor necrosis factor-α gene promoter polymorphism at sites -308 and -238 with non-alcoholic fatty liver disease: a meta-analysis
    • Wang J.K., Feng Z.W., Li Y.C., Li Q.Y., Tao X.Y. Association of tumor necrosis factor-α gene promoter polymorphism at sites -308 and -238 with non-alcoholic fatty liver disease: a meta-analysis. J. Gastroenterol. Hepatol. 2012, 27:670-676.
    • (2012) J. Gastroenterol. Hepatol. , vol.27 , pp. 670-676
    • Wang, J.K.1    Feng, Z.W.2    Li, Y.C.3    Li, Q.Y.4    Tao, X.Y.5
  • 85
    • 79960943280 scopus 로고    scopus 로고
    • Polymorphisms of tumor necrosis factor-alpha and hepatocellular carcinoma risk: a HuGE systematic review and meta-analysis
    • Wei Y., Liu F., Li B., Chen X., Ma Y., Yan L., Wen T., Xu M., Wang W., Yang J. Polymorphisms of tumor necrosis factor-alpha and hepatocellular carcinoma risk: a HuGE systematic review and meta-analysis. Dig. Dis. Sci. 2011, 56:2227-2236.
    • (2011) Dig. Dis. Sci. , vol.56 , pp. 2227-2236
    • Wei, Y.1    Liu, F.2    Li, B.3    Chen, X.4    Ma, Y.5    Yan, L.6    Wen, T.7    Xu, M.8    Wang, W.9    Yang, J.10
  • 86
    • 3342968806 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha in the pathogenesis and treatment of cancer
    • Anderson G.M., Nakada M.T., DeWitte M. Tumor necrosis factor-alpha in the pathogenesis and treatment of cancer. Curr. Opin. Pharmacol. 2004, 4:314-320.
    • (2004) Curr. Opin. Pharmacol. , vol.4 , pp. 314-320
    • Anderson, G.M.1    Nakada, M.T.2    DeWitte, M.3
  • 87
    • 58149510582 scopus 로고    scopus 로고
    • Association between combinations of glutathione-S-transferase M1, T1 and P1 genotypes and non-alcoholic fatty liver disease
    • Hori M., Oniki K., Nakagawa T., Takata K., Mihara S., Marubayashi T., Nakagawa K. Association between combinations of glutathione-S-transferase M1, T1 and P1 genotypes and non-alcoholic fatty liver disease. Liver Int. 2009, 29:164-168.
    • (2009) Liver Int. , vol.29 , pp. 164-168
    • Hori, M.1    Oniki, K.2    Nakagawa, T.3    Takata, K.4    Mihara, S.5    Marubayashi, T.6    Nakagawa, K.7
  • 88
    • 77955850169 scopus 로고    scopus 로고
    • Null genotypes of GSTM1 and GSTT1 contribute to hepatocellular carcinoma risk: evidence from an updated meta-analysis
    • Wang B., Huang G., Wang D., Li A., Xu Z., Dong R., Zhang D., Zhou W. Null genotypes of GSTM1 and GSTT1 contribute to hepatocellular carcinoma risk: evidence from an updated meta-analysis. J. Hepatol. 2010, 53:508-518.
    • (2010) J. Hepatol. , vol.53 , pp. 508-518
    • Wang, B.1    Huang, G.2    Wang, D.3    Li, A.4    Xu, Z.5    Dong, R.6    Zhang, D.7    Zhou, W.8
  • 89
    • 84875378443 scopus 로고    scopus 로고
    • Null genotypes of GSTM1 and GSTT1 contribute to increased risk of diabetes mellitus: a meta-analysis
    • Zhang J., Liu H., Yan H., Huang G., Wang B. Null genotypes of GSTM1 and GSTT1 contribute to increased risk of diabetes mellitus: a meta-analysis. Gene 2013, 518(2):405-411.
    • (2013) Gene , vol.518 , Issue.2 , pp. 405-411
    • Zhang, J.1    Liu, H.2    Yan, H.3    Huang, G.4    Wang, B.5
  • 90
    • 84875231712 scopus 로고    scopus 로고
    • Null genotypes of GSTM1 and GSTT1 contribute to male factor infertility risk: a meta-analysis
    • Kan H.P., Wu F.L., Guo W.B., Wang Y.Z., Li J.P., Huang Y.Q., Li S.G., Liu J.P. Null genotypes of GSTM1 and GSTT1 contribute to male factor infertility risk: a meta-analysis. Fertil. Steril. 2012, 99(3):690-696.
    • (2012) Fertil. Steril. , vol.99 , Issue.3 , pp. 690-696
    • Kan, H.P.1    Wu, F.L.2    Guo, W.B.3    Wang, Y.Z.4    Li, J.P.5    Huang, Y.Q.6    Li, S.G.7    Liu, J.P.8
  • 91
    • 78349283454 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor alpha target genes
    • (Epub)
    • Rakhshandehroo M., Knoch B., Muller M., Kersten S. Peroxisome proliferator-activated receptor alpha target genes. PPAR Res. 2010, 2010. (Epub). 10.1155/2010/612089.
    • (2010) PPAR Res. , vol.2010
    • Rakhshandehroo, M.1    Knoch, B.2    Muller, M.3    Kersten, S.4
  • 93
    • 33645891166 scopus 로고    scopus 로고
    • Effects of bezafibrate, PPAR pan-agonist, and GW501516, PPARdelta agonist, on development of steatohepatitis in mice fed a methionine- and choline-deficient diet
    • Nagasawa T., Inada Y., Nakano S., Tamura T., Takahashi T., Maruyama K., Yamazaki Y., Kuroda J., Shibata N. Effects of bezafibrate, PPAR pan-agonist, and GW501516, PPARdelta agonist, on development of steatohepatitis in mice fed a methionine- and choline-deficient diet. Eur. J. Pharmacol. 2006, 536:182-191.
    • (2006) Eur. J. Pharmacol. , vol.536 , pp. 182-191
    • Nagasawa, T.1    Inada, Y.2    Nakano, S.3    Tamura, T.4    Takahashi, T.5    Maruyama, K.6    Yamazaki, Y.7    Kuroda, J.8    Shibata, N.9
  • 94
    • 0028997684 scopus 로고
    • Targeted disruption of the alpha isoform of the peroxisome proliferator-activated receptor gene in mice results in abolishment of the pleiotropic effects of peroxisome proliferators
    • Lee S.S., Pineau T., Drago J., Lee E.J., Owens J.W., Kroetz D.L., Fernandez-Salguero P.M., Westphal H., Gonzalez F.J. Targeted disruption of the alpha isoform of the peroxisome proliferator-activated receptor gene in mice results in abolishment of the pleiotropic effects of peroxisome proliferators. Mol. Cell. Biol. 1995, 15:3012-3022.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 3012-3022
    • Lee, S.S.1    Pineau, T.2    Drago, J.3    Lee, E.J.4    Owens, J.W.5    Kroetz, D.L.6    Fernandez-Salguero, P.M.7    Westphal, H.8    Gonzalez, F.J.9
  • 95
    • 0023879854 scopus 로고
    • Effects of fibrates on serum lipids and atherosclerosis
    • Sirtori C.R., Franceschini G. Effects of fibrates on serum lipids and atherosclerosis. Pharmacol. Ther. 1988, 37:167-191.
    • (1988) Pharmacol. Ther. , vol.37 , pp. 167-191
    • Sirtori, C.R.1    Franceschini, G.2
  • 96
    • 0036009175 scopus 로고    scopus 로고
    • A Val227Ala polymorphism in the peroxisome proliferator activated receptor alpha (PPARalpha) gene is associated with variations in serum lipid levels
    • Yamakawa-Kobayashi K., Ishiguro H., Arinami T., Miyazaki R., Hamaguchi H. A Val227Ala polymorphism in the peroxisome proliferator activated receptor alpha (PPARalpha) gene is associated with variations in serum lipid levels. J. Med. Genet. 2002, 39:189-191.
    • (2002) J. Med. Genet. , vol.39 , pp. 189-191
    • Yamakawa-Kobayashi, K.1    Ishiguro, H.2    Arinami, T.3    Miyazaki, R.4    Hamaguchi, H.5
  • 98
    • 49849093922 scopus 로고    scopus 로고
    • A Val227Ala substitution in the peroxisome proliferator activated receptor alpha (PPAR alpha) gene associated with non-alcoholic fatty liver disease and decreased waist circumference and waist-to-hip ratio
    • Chen S., Li Y., Li S., Yu C. A Val227Ala substitution in the peroxisome proliferator activated receptor alpha (PPAR alpha) gene associated with non-alcoholic fatty liver disease and decreased waist circumference and waist-to-hip ratio. J. Gastroenterol. Hepatol. 2008, 23:1415-1418.
    • (2008) J. Gastroenterol. Hepatol. , vol.23 , pp. 1415-1418
    • Chen, S.1    Li, Y.2    Li, S.3    Yu, C.4
  • 100
    • 64549127790 scopus 로고    scopus 로고
    • PGC-1alpha, SIRT1 and AMPK, an energy sensing network that controls energy expenditure
    • Canto C., Auwerx J. PGC-1alpha, SIRT1 and AMPK, an energy sensing network that controls energy expenditure. Curr. Opin. Lipidol. 2009, 20:98-105.
    • (2009) Curr. Opin. Lipidol. , vol.20 , pp. 98-105
    • Canto, C.1    Auwerx, J.2
  • 101
    • 78649568544 scopus 로고    scopus 로고
    • Epigenetic regulation of insulin resistance in nonalcoholic fatty liver disease: impact of liver methylation of the peroxisome proliferator-activated receptor gamma coactivator 1alpha promoter
    • Sookoian S., Rosselli M.S., Gemma C., Burgueno A.L., Fernandez Gianotti T., Castano G.O., Pirola C.J. Epigenetic regulation of insulin resistance in nonalcoholic fatty liver disease: impact of liver methylation of the peroxisome proliferator-activated receptor gamma coactivator 1alpha promoter. Hepatology 2010, 52:1992-2000.
    • (2010) Hepatology , vol.52 , pp. 1992-2000
    • Sookoian, S.1    Rosselli, M.S.2    Gemma, C.3    Burgueno, A.L.4    Fernandez Gianotti, T.5    Castano, G.O.6    Pirola, C.J.7
  • 103
    • 77956864571 scopus 로고    scopus 로고
    • Berberine reduces methylation of the MTTP promoter and alleviates fatty liver induced by a high-fat diet in rats
    • Chang X., Yan H., Fei J., Jiang M., Zhu H., Lu D., Gao X. Berberine reduces methylation of the MTTP promoter and alleviates fatty liver induced by a high-fat diet in rats. J. Lipid Res. 2010, 51:2504-2515.
    • (2010) J. Lipid Res. , vol.51 , pp. 2504-2515
    • Chang, X.1    Yan, H.2    Fei, J.3    Jiang, M.4    Zhu, H.5    Lu, D.6    Gao, X.7
  • 104
    • 34248657027 scopus 로고    scopus 로고
    • Polymorphism in microsomal triglyceride transfer protein: a link between liver disease and atherogenic postprandial lipid profile in NASH?
    • Gambino R., Cassader M., Pagano G., Durazzo M., Musso G. Polymorphism in microsomal triglyceride transfer protein: a link between liver disease and atherogenic postprandial lipid profile in NASH?. Hepatology 2007, 45:1097-1107.
    • (2007) Hepatology , vol.45 , pp. 1097-1107
    • Gambino, R.1    Cassader, M.2    Pagano, G.3    Durazzo, M.4    Musso, G.5
  • 105
    • 0036829872 scopus 로고    scopus 로고
    • An unexpected requirement for phosphatidylethanolamine N-methyltransferase in the secretion of very low density lipoproteins
    • Noga A.A., Zhao Y., Vance D.E. An unexpected requirement for phosphatidylethanolamine N-methyltransferase in the secretion of very low density lipoproteins. J. Biol. Chem. 2002, 277:42358-42365.
    • (2002) J. Biol. Chem. , vol.277 , pp. 42358-42365
    • Noga, A.A.1    Zhao, Y.2    Vance, D.E.3
  • 106
    • 23444435961 scopus 로고    scopus 로고
    • Polymorphism of the PEMT gene and susceptibility to nonalcoholic fatty liver disease (NAFLD)
    • Song J., da Costa K.A., Fischer L.M., Kohlmeier M., Kwock L., Wang S., Zeisel S.H. Polymorphism of the PEMT gene and susceptibility to nonalcoholic fatty liver disease (NAFLD). FASEB J. 2005, 19:1266-1271.
    • (2005) FASEB J. , vol.19 , pp. 1266-1271
    • Song, J.1    da Costa, K.A.2    Fischer, L.M.3    Kohlmeier, M.4    Kwock, L.5    Wang, S.6    Zeisel, S.H.7
  • 107
    • 34047116836 scopus 로고    scopus 로고
    • The phosphatidylethanolamine N-methyltransferase gene V175M single nucleotide polymorphism confers the susceptibility to NASH in Japanese population
    • Dong H., Wang J., Li C., Hirose A., Nozaki Y., Takahashi M., Ono M., Akisawa N., Iwasaki S., Saibara T., Onishi S. The phosphatidylethanolamine N-methyltransferase gene V175M single nucleotide polymorphism confers the susceptibility to NASH in Japanese population. J. Hepatol. 2007, 46:915-920.
    • (2007) J. Hepatol. , vol.46 , pp. 915-920
    • Dong, H.1    Wang, J.2    Li, C.3    Hirose, A.4    Nozaki, Y.5    Takahashi, M.6    Ono, M.7    Akisawa, N.8    Iwasaki, S.9    Saibara, T.10    Onishi, S.11
  • 110
    • 79251523832 scopus 로고    scopus 로고
    • Dissociation between APOC3 variants, hepatic triglyceride content and insulin resistance
    • Kozlitina J., Boerwinkle E., Cohen J.C., Hobbs H.H. Dissociation between APOC3 variants, hepatic triglyceride content and insulin resistance. Hepatology 2011, 53:467-474.
    • (2011) Hepatology , vol.53 , pp. 467-474
    • Kozlitina, J.1    Boerwinkle, E.2    Cohen, J.C.3    Hobbs, H.H.4
  • 113
    • 84860389880 scopus 로고    scopus 로고
    • Deficiency in apolipoprotein E has a protective effect on diet-induced nonalcoholic fatty liver disease in mice
    • Karavia E.A., Papachristou D.J., Kotsikogianni I., Giopanou I., Kypreos K.E. Deficiency in apolipoprotein E has a protective effect on diet-induced nonalcoholic fatty liver disease in mice. FEBS J. 2011, 278(17):3119-3129.
    • (2011) FEBS J. , vol.278 , Issue.17 , pp. 3119-3129
    • Karavia, E.A.1    Papachristou, D.J.2    Kotsikogianni, I.3    Giopanou, I.4    Kypreos, K.E.5
  • 115
    • 55949083698 scopus 로고    scopus 로고
    • Association of apolipoprotein E polymorphisms in patients with non-alcoholic steatohepatitis
    • Sazci A., Akpinar G., Aygun C., Ergul E., Senturk O., Hulagu S. Association of apolipoprotein E polymorphisms in patients with non-alcoholic steatohepatitis. Dig. Dis. Sci. 2008, 53:3218-3224.
    • (2008) Dig. Dis. Sci. , vol.53 , pp. 3218-3224
    • Sazci, A.1    Akpinar, G.2    Aygun, C.3    Ergul, E.4    Senturk, O.5    Hulagu, S.6
  • 118
    • 42249084876 scopus 로고    scopus 로고
    • Adiponectin gene polymorphisms modulate acute adiponectin response to dietary fat: possible pathogenetic role in NASH
    • Musso G., Gambino R., De Michieli F., Durazzo M., Pagano G., Cassader M. Adiponectin gene polymorphisms modulate acute adiponectin response to dietary fat: possible pathogenetic role in NASH. Hepatology 2008, 47:1167-1177.
    • (2008) Hepatology , vol.47 , pp. 1167-1177
    • Musso, G.1    Gambino, R.2    De Michieli, F.3    Durazzo, M.4    Pagano, G.5    Cassader, M.6
  • 119
    • 79953321200 scopus 로고    scopus 로고
    • Genetic determinants of hepatic steatosis in man
    • Hooper A.J., Adams L.A., Burnett J.R. Genetic determinants of hepatic steatosis in man. J. Lipid Res. 2011, 52:593-617.
    • (2011) J. Lipid Res. , vol.52 , pp. 593-617
    • Hooper, A.J.1    Adams, L.A.2    Burnett, J.R.3
  • 120
    • 18844432308 scopus 로고    scopus 로고
    • Adiponectin and adiponectin receptors
    • Kadowaki T., Yamauchi T. Adiponectin and adiponectin receptors. Endocr. Rev. 2005, 26:439-451.
    • (2005) Endocr. Rev. , vol.26 , pp. 439-451
    • Kadowaki, T.1    Yamauchi, T.2
  • 122
    • 0036830636 scopus 로고    scopus 로고
    • SOCS-1 and SOCS-3 block insulin signaling by ubiquitin-mediated degradation of IRS1 and IRS2
    • Rui L., Yuan M., Frantz D., Shoelson S., White M.F. SOCS-1 and SOCS-3 block insulin signaling by ubiquitin-mediated degradation of IRS1 and IRS2. J. Biol. Chem. 2002, 277:42394-42398.
    • (2002) J. Biol. Chem. , vol.277 , pp. 42394-42398
    • Rui, L.1    Yuan, M.2    Frantz, D.3    Shoelson, S.4    White, M.F.5
  • 125
    • 84871076695 scopus 로고    scopus 로고
    • Essential roles of growth hormone (GH) and insulin-like growth factor-I (IGF-I) in the liver
    • Takahashi Y. Essential roles of growth hormone (GH) and insulin-like growth factor-I (IGF-I) in the liver. Endocr. J. 2012, 59:955-962.
    • (2012) Endocr. J. , vol.59 , pp. 955-962
    • Takahashi, Y.1
  • 126
    • 0034803527 scopus 로고    scopus 로고
    • Insulin-like growth factor 1 (IGF-1): a growth hormone
    • Laron Z. Insulin-like growth factor 1 (IGF-1): a growth hormone. Mol. Pathol. 2001, 54:311-316.
    • (2001) Mol. Pathol. , vol.54 , pp. 311-316
    • Laron, Z.1
  • 127
    • 84862902026 scopus 로고    scopus 로고
    • GH-independent IGF-I action is essential to prevent the development of nonalcoholic steatohepatitis in a GH-deficient rat model
    • Nishizawa H., Takahashi M., Fukuoka H., Iguchi G., Kitazawa R., Takahashi Y. GH-independent IGF-I action is essential to prevent the development of nonalcoholic steatohepatitis in a GH-deficient rat model. Biochem. Biophys. Res. Commun. 2012, 423:295-300.
    • (2012) Biochem. Biophys. Res. Commun. , vol.423 , pp. 295-300
    • Nishizawa, H.1    Takahashi, M.2    Fukuoka, H.3    Iguchi, G.4    Kitazawa, R.5    Takahashi, Y.6
  • 130
    • 78650939590 scopus 로고    scopus 로고
    • Metabolic parameters and nonalcoholic fatty liver disease in hypopituitary men
    • Hong J.W., Kim J.Y., Kim Y.E., Lee E.J. Metabolic parameters and nonalcoholic fatty liver disease in hypopituitary men. Horm. Metab. Res. 2011, 43:48-54.
    • (2011) Horm. Metab. Res. , vol.43 , pp. 48-54
    • Hong, J.W.1    Kim, J.Y.2    Kim, Y.E.3    Lee, E.J.4
  • 135
    • 0037853260 scopus 로고    scopus 로고
    • Suppressor of cytokine signaling-3 (SOCS-3), a potential mediator of interleukin-6-dependent insulin resistance in hepatocytes
    • Senn J.J., Klover P.J., Nowak I.A., Zimmers T.A., Koniaris L.G., Furlanetto R.W., Mooney R.A. Suppressor of cytokine signaling-3 (SOCS-3), a potential mediator of interleukin-6-dependent insulin resistance in hepatocytes. J. Biol. Chem. 2003, 278:13740-13746.
    • (2003) J. Biol. Chem. , vol.278 , pp. 13740-13746
    • Senn, J.J.1    Klover, P.J.2    Nowak, I.A.3    Zimmers, T.A.4    Koniaris, L.G.5    Furlanetto, R.W.6    Mooney, R.A.7
  • 136
    • 15444366991 scopus 로고    scopus 로고
    • Metabolic syndrome: a comprehensive perspective based on interactions between obesity, diabetes, and inflammation
    • Dandona P., Aljada A., Chaudhuri A., Mohanty P., Garg R. Metabolic syndrome: a comprehensive perspective based on interactions between obesity, diabetes, and inflammation. Circulation 2005, 111:1448-1454.
    • (2005) Circulation , vol.111 , pp. 1448-1454
    • Dandona, P.1    Aljada, A.2    Chaudhuri, A.3    Mohanty, P.4    Garg, R.5
  • 137
    • 0034625547 scopus 로고    scopus 로고
    • Plasma interleukin-6, tumour necrosis factor alpha and blood cytokine production in type 2 diabetes
    • Pickup J.C., Chusney G.D., Thomas S.M., Burt D. Plasma interleukin-6, tumour necrosis factor alpha and blood cytokine production in type 2 diabetes. Life Sci. 2000, 67:291-300.
    • (2000) Life Sci. , vol.67 , pp. 291-300
    • Pickup, J.C.1    Chusney, G.D.2    Thomas, S.M.3    Burt, D.4
  • 139
    • 84875218268 scopus 로고    scopus 로고
    • Molecular interactions between NAFLD and xenobiotic metabolism, Front. Gene 4 (2).
    • A. Naik, A. Belič, U.M. Zanger, D. Rozman, Molecular interactions between NAFLD and xenobiotic metabolism, Front. Gene 4 (2).
    • Naik, A.1    Belič, A.2    Zanger, U.M.3    Rozman, D.4
  • 140
    • 33744948052 scopus 로고    scopus 로고
    • A novel pregnane X receptor-mediated and sterol regulatory element-binding protein-independent lipogenic pathway
    • Zhou J., Zhai Y., Mu Y., Gong H., Uppal H., Toma D., Ren S., Evans R.M., Xie W. A novel pregnane X receptor-mediated and sterol regulatory element-binding protein-independent lipogenic pathway. J. Biol. Chem. 2006, 281:15013-15020.
    • (2006) J. Biol. Chem. , vol.281 , pp. 15013-15020
    • Zhou, J.1    Zhai, Y.2    Mu, Y.3    Gong, H.4    Uppal, H.5    Toma, D.6    Ren, S.7    Evans, R.M.8    Xie, W.9
  • 142
    • 71949122207 scopus 로고    scopus 로고
    • Variants in the UGT1A1 gene and the risk of pediatric nonalcoholic fatty liver disease
    • Lin Y.C., Chang P.F., Hu F.C., Chang M.H., Ni Y.H. Variants in the UGT1A1 gene and the risk of pediatric nonalcoholic fatty liver disease. Pediatrics 2009, 124:e1221-e1227.
    • (2009) Pediatrics , vol.124
    • Lin, Y.C.1    Chang, P.F.2    Hu, F.C.3    Chang, M.H.4    Ni, Y.H.5
  • 143
    • 69749107591 scopus 로고    scopus 로고
    • Polymorphisms of MRP2 (ABCC2) are associated with susceptibility to nonalcoholic fatty liver disease
    • Sookoian S., Castano G., Gianotti T.F., Gemma C., Pirola C.J. Polymorphisms of MRP2 (ABCC2) are associated with susceptibility to nonalcoholic fatty liver disease. J. Nutr. Biochem. 2009, 20:765-770.
    • (2009) J. Nutr. Biochem. , vol.20 , pp. 765-770
    • Sookoian, S.1    Castano, G.2    Gianotti, T.F.3    Gemma, C.4    Pirola, C.J.5
  • 145
    • 79957521377 scopus 로고    scopus 로고
    • Pathologic criteria for nonalcoholic steatohepatitis: interprotocol agreement and ability to predict liver-related mortality
    • Younossi Z.M., Stepanova M., Rafiq N., Makhlouf H., Younoszai Z., Agrawal R., Goodman Z. Pathologic criteria for nonalcoholic steatohepatitis: interprotocol agreement and ability to predict liver-related mortality. Hepatology 2011, 53:1874-1882.
    • (2011) Hepatology , vol.53 , pp. 1874-1882
    • Younossi, Z.M.1    Stepanova, M.2    Rafiq, N.3    Makhlouf, H.4    Younoszai, Z.5    Agrawal, R.6    Goodman, Z.7
  • 148
    • 84859844118 scopus 로고    scopus 로고
    • Circadian regulation of the hepatic endobiotic and xenobitoic detoxification pathways: the time matters
    • Zmrzljak U.P., Rozman D. Circadian regulation of the hepatic endobiotic and xenobitoic detoxification pathways: the time matters. Chem. Res. Toxicol. 2012, 25:811-824.
    • (2012) Chem. Res. Toxicol. , vol.25 , pp. 811-824
    • Zmrzljak, U.P.1    Rozman, D.2
  • 149
  • 150
    • 79956197436 scopus 로고    scopus 로고
    • Circadian rhythm of cholesterol synthesis in mouse liver: a statistical analysis of the post-squalene metabolites in wild-type and Crem-knock-out mice
    • Ačimovič J., Košir R., Kastelec D., Perše M., Majdič G., Rozman D., Košmelj K., Goličnik M. Circadian rhythm of cholesterol synthesis in mouse liver: a statistical analysis of the post-squalene metabolites in wild-type and Crem-knock-out mice. Biochem. Biophys. Res. Commun. 2011, 408:635-641.
    • (2011) Biochem. Biophys. Res. Commun. , vol.408 , pp. 635-641
    • Ačimovič, J.1    Košir, R.2    Kastelec, D.3    Perše, M.4    Majdič, G.5    Rozman, D.6    Košmelj, K.7    Goličnik, M.8
  • 151
    • 84860215808 scopus 로고    scopus 로고
    • Circadian expression of steroidogenic cytochromes P450 in the mouse adrenal gland-involvement of cAMP-responsive element modulator in epigenetic regulation of Cyp17a1
    • Košir R., Zmrzljak U.P., Bele T., Acimovic J., Perse M., Majdic G., Prehn C., Adamski J., Rozman D. Circadian expression of steroidogenic cytochromes P450 in the mouse adrenal gland-involvement of cAMP-responsive element modulator in epigenetic regulation of Cyp17a1. FEBS J. 2012, 279:1584-1593.
    • (2012) FEBS J. , vol.279 , pp. 1584-1593
    • Košir, R.1    Zmrzljak, U.P.2    Bele, T.3    Acimovic, J.4    Perse, M.5    Majdic, G.6    Prehn, C.7    Adamski, J.8    Rozman, D.9
  • 152
    • 70450239457 scopus 로고    scopus 로고
    • Metabolism and cancer: the circadian clock connection
    • Sahar S., Sassone-Corsi P. Metabolism and cancer: the circadian clock connection. Nat. Rev. Cancer 2009, 9:886-896.
    • (2009) Nat. Rev. Cancer , vol.9 , pp. 886-896
    • Sahar, S.1    Sassone-Corsi, P.2
  • 155
    • 84871676465 scopus 로고    scopus 로고
    • Circadian clock genes Per1 and Per2 regulate the response of metabolism-associated transcripts to sleep disruption
    • Husse J., Hintze S.C., Eichele G., Lehnert H., Oster H. Circadian clock genes Per1 and Per2 regulate the response of metabolism-associated transcripts to sleep disruption. PLoS One 2012, 7:e52983.
    • (2012) PLoS One , vol.7
    • Husse, J.1    Hintze, S.C.2    Eichele, G.3    Lehnert, H.4    Oster, H.5
  • 156
    • 84860225393 scopus 로고    scopus 로고
    • Cytochrome P450s in the synthesis of cholesterol and bile acids - from mouse models to human diseases
    • Lorbek G., Lewinska M., Rozman D. Cytochrome P450s in the synthesis of cholesterol and bile acids - from mouse models to human diseases. FEBS J. 2011, 279(9):1516-1533.
    • (2011) FEBS J. , vol.279 , Issue.9 , pp. 1516-1533
    • Lorbek, G.1    Lewinska, M.2    Rozman, D.3
  • 157
    • 79951931318 scopus 로고    scopus 로고
    • Defects in cholesterol synthesis genes in mouse and in humans: lessons for drug development and safer treatments
    • Horvat S., McWhir J., Rozman D. Defects in cholesterol synthesis genes in mouse and in humans: lessons for drug development and safer treatments. Drug Metab. Rev. 2011, 43:69-90.
    • (2011) Drug Metab. Rev. , vol.43 , pp. 69-90
    • Horvat, S.1    McWhir, J.2    Rozman, D.3
  • 158
    • 84878226490 scopus 로고    scopus 로고
    • Diurnal variation in vascular and metabolic function in diet-induced obesity: divergence of insulin resistance and loss of clock rhythm
    • [Electronic publication ahead of print]
    • Prasai M.J., Mughal R.S., Wheatcroft S.B., Kearney M.T., Grant P.J., Scott E.M. Diurnal variation in vascular and metabolic function in diet-induced obesity: divergence of insulin resistance and loss of clock rhythm. Diabetes 2013, [Electronic publication ahead of print].
    • (2013) Diabetes
    • Prasai, M.J.1    Mughal, R.S.2    Wheatcroft, S.B.3    Kearney, M.T.4    Grant, P.J.5    Scott, E.M.6
  • 161
    • 78650883004 scopus 로고    scopus 로고
    • The circadian clock and metabolism
    • Froy O. The circadian clock and metabolism. Clin. Sci. (Lond.) 2011, 120:65-72.
    • (2011) Clin. Sci. (Lond.) , vol.120 , pp. 65-72
    • Froy, O.1
  • 162
    • 69949097413 scopus 로고    scopus 로고
    • Shift work is a risk factor for increased total cholesterol level: a 14-year prospective cohort study in 6886 male workers
    • Dochi M., Suwazono Y., Sakata K., Okubo Y., Oishi M., Tanaka K., Kobayashi E., Nogawa K. Shift work is a risk factor for increased total cholesterol level: a 14-year prospective cohort study in 6886 male workers. Occup. Environ. Med. 2009, 66:592-597.
    • (2009) Occup. Environ. Med. , vol.66 , pp. 592-597
    • Dochi, M.1    Suwazono, Y.2    Sakata, K.3    Okubo, Y.4    Oishi, M.5    Tanaka, K.6    Kobayashi, E.7    Nogawa, K.8
  • 163
    • 84856866840 scopus 로고    scopus 로고
    • Stress and the gut: pathophysiology, clinical consequences, diagnostic approach and treatment options
    • Konturek P.C., Brzozowski T., Konturek S.J. Stress and the gut: pathophysiology, clinical consequences, diagnostic approach and treatment options. J. Physiol. Pharmacol. 2011, 62:591-599.
    • (2011) J. Physiol. Pharmacol. , vol.62 , pp. 591-599
    • Konturek, P.C.1    Brzozowski, T.2    Konturek, S.J.3
  • 164
    • 77951297855 scopus 로고    scopus 로고
    • Altered circadian rhythm of the clock genes in fibrotic livers induced by carbon tetrachloride
    • Chen P., Kakan X., Zhang J. Altered circadian rhythm of the clock genes in fibrotic livers induced by carbon tetrachloride. FEBS Lett. 2010, 584:1597-1601.
    • (2010) FEBS Lett. , vol.584 , pp. 1597-1601
    • Chen, P.1    Kakan, X.2    Zhang, J.3
  • 166
    • 39849090020 scopus 로고    scopus 로고
    • Identification of coding polymorphisms in human circadian rhythm genes PER1, PER2, PER3, CLOCK, ARNTL, CRY1, CRY2 and TIMELESS in a multi-ethnic screening panel
    • Hawkins G.A., Meyers D.A., Bleecker E.R., Pack A.I. Identification of coding polymorphisms in human circadian rhythm genes PER1, PER2, PER3, CLOCK, ARNTL, CRY1, CRY2 and TIMELESS in a multi-ethnic screening panel. DNA Seq. 2008, 19:44-49.
    • (2008) DNA Seq. , vol.19 , pp. 44-49
    • Hawkins, G.A.1    Meyers, D.A.2    Bleecker, E.R.3    Pack, A.I.4
  • 167
    • 84865715920 scopus 로고    scopus 로고
    • A functional polymorphism in PER3 gene is associated with prognosis in hepatocellular carcinoma
    • Zhao B., Lu J., Yin J., Liu H., Guo X., Yang Y., Ge N., Zhu Y., Zhang H., Xing J. A functional polymorphism in PER3 gene is associated with prognosis in hepatocellular carcinoma. Liver Int. 2012, 32:1451-1459.
    • (2012) Liver Int. , vol.32 , pp. 1451-1459
    • Zhao, B.1    Lu, J.2    Yin, J.3    Liu, H.4    Guo, X.5    Yang, Y.6    Ge, N.7    Zhu, Y.8    Zhang, H.9    Xing, J.10
  • 168
    • 34548480183 scopus 로고    scopus 로고
    • Common genetic variations in CLOCK transcription factor are associated with nonalcoholic fatty liver disease
    • Sookoian S., Castaño G., Gemma C., Gianotti T.F., Pirola C.J. Common genetic variations in CLOCK transcription factor are associated with nonalcoholic fatty liver disease. World J. Gastroenterol. 2007, 13:4242-4248.
    • (2007) World J. Gastroenterol. , vol.13 , pp. 4242-4248
    • Sookoian, S.1    Castaño, G.2    Gemma, C.3    Gianotti, T.F.4    Pirola, C.J.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.