Unsaturated fatty acids promote hepatoma proliferation and progression through downregulation of the tumor suppressor PTEN

Journal of Hepatology

Volumn 50, Issue 6, 2009, Pages 1132-1141

  Vinciguerra, Manlio ^a   Carrozzino, Fabio ^a   Peyrou, Marion ^a   Carlone, Sebastiano ^b   Montesano, Roberto ^a   Benelli, Roberto ^b   Foti, Michelangelo ^a  

^a UNIVERSITY OF GENEVA   (Switzerland)

^b UNIVERSITY OF GENOA   (Italy)

Author keywords

Cancer; Hepatocytes; mTOR; NF Bp65; PTEN; UFAs

Indexed keywords

OLEIC ACID; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PYRROLIDINE DITHIOCARBAMATE; RAPAMYCIN; SMALL INTERFERING RNA; UNSATURATED FATTY ACID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER GROWTH; CELL INVASION; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; DOWN REGULATION; GENE EXPRESSION; HUMAN; HUMAN CELL; INFLAMMATION; LIPID DIET; LIVER CARCINOGENESIS; LIVER CELL CARCINOMA; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; TUMOR VOLUME; TUMOR XENOGRAFT; WEIGHT GAIN;

ANIMALS; APOPTOSIS; BASE SEQUENCE; CARCINOGENS; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; DNA PRIMERS; DOWN-REGULATION; FATTY ACIDS, UNSATURATED; HEPATOCYTES; HUMANS; LIVER NEOPLASMS, EXPERIMENTAL; MICE; MICE, NUDE; NEOPLASM TRANSPLANTATION; PTEN PHOSPHOHYDROLASE; RECOMBINANT FUSION PROTEINS; RISK FACTORS; RNA, SMALL INTERFERING; TRANSFECTION; TRANSPLANTATION, HETEROLOGOUS;

EID: 67349210047     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jhep.2009.01.027     Document Type: Article

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