Leptin stimulates fatty-acid oxidation by activating AMP-activated protein kinase

Nature

Volumn 415, Issue 6869, 2002, Pages 339-343

  Minokoshi, Yasuhiko ^a   Kim, Young Bum ^a   Peroni, Odile D ^a   Fryer, Lee G D ^b   Müller, Corinna ^a   Carling, David ^b   Kahn, Barbara B ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b HAMMERSMITH HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ENZYME INHIBITION; ENZYMES; FATTY ACIDS; GLUCOSE; METABOLISM; MUSCLE; OXIDATION;

NONADIPOSE TISSUES;

HORMONES;

ACETYL COENZYME A CARBOXYLASE; FATTY ACID; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; LEPTIN; PROTEIN KINASE; UNCLASSIFIED DRUG;

FATTY ACID; METABOLISM; OXIDATION;

ADIPOCYTE; ADRENERGIC SYSTEM; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL ENERGY; CONTROLLED STUDY; ENERGY EXPENDITURE; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; FATTY ACID OXIDATION; FOOD INTAKE; HORMONAL REGULATION; HORMONE ACTION; HYPOTHALAMUS; LIPID STORAGE; LIPOTOXICITY; MALE; MOUSE; MUSCLE METABOLISM; NEUROENDOCRINE SYSTEM; NONHUMAN; PRIORITY JOURNAL; SOLEUS MUSCLE;

ACETYL-COA CARBOXYLASE; ADRENERGIC ALPHA-ANTAGONISTS; ADRENERGIC BETA-AGONISTS; ANIMALS; CATALYTIC DOMAIN; ENZYME ACTIVATION; FATTY ACIDS; ISOPROTERENOL; LEPTIN; LIPID METABOLISM; MALE; MICE; MULTIENZYME COMPLEXES; MUSCLE, SKELETAL; OXIDATION-REDUCTION; PHENTOLAMINE; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; SIGNAL TRANSDUCTION; SYMPATHETIC NERVOUS SYSTEM;

ANIMALIA;

EID: 0037122766     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/415339a     Document Type: Article

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