Detection and repair of ionizing radiation-induced dna double strand breaks: New developments in nonhomologous end joining

International Journal of Radiation Oncology Biology Physics

Volumn 86, Issue 3, 2013, Pages 440-449

  Wang, Chen ^a   Lees Miller, Susan P ^a,b  

^a UNIVERSITY OF CALGARY   (Canada)

^b UNIVERSITY OF CALGARY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOTHERAPY; DNA; IONIZING RADIATION; JOINING; RADIATION SHIELDING; REPAIR;

DETECTION AND REPAIRS; DNA DAMAGES; DNA DOUBLE STRAND BREAKS; EXOGENOUS SOURCE; GENOME INSTABILITY; HUMAN CELLS; METABOLIC REACTIONS; NONHOMOLOGOUS END JOINING;

RADIOTHERAPY;

CAMPTOTHECIN; DNA LIGASE 4; DOUBLE STRANDED DNA; KU ANTIGEN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE INHIBITOR; POLYDEOXYRIBONUCLEOTIDE SYNTHASE; PROTEIN KINASE C; PROTEIN KINASE C INHIBITOR; UNCLASSIFIED DRUG; XRCC4 PROTEIN; CELL NUCLEUS ANTIGEN; DNA BINDING PROTEIN; DNA DEPENDENT PROTEIN KINASE; NHEJ1 PROTEIN, HUMAN; NUCLEAR PROTEIN; POLYDEOXYRIBONUCLEOTIDE SYNTHASE (ATP); PRKDC PROTEIN, HUMAN; XRCC4 PROTEIN, HUMAN;

ARTICLE; AUTOPHOSPHORYLATION; CONFORMATIONAL TRANSITION; DNA BINDING; DNA END JOINING REPAIR; DNA PROTEIN COMPLEX; DOUBLE STRANDED DNA BREAK; DRUG EFFICACY; ENZYME ACTIVITY; HUMAN; IN VITRO STUDY; IN VIVO STUDY; IONIZING RADIATION; NONHUMAN; PHASE 1 CLINICAL TRIAL (TOPIC); PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DNA INTERACTION; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEOMICS; SIGNAL TRANSDUCTION; UBIQUITINATION; PHOSPHORYLATION; PHYSIOLOGY; REVIEW;

ANTIGENS, NUCLEAR; DNA BREAKS, DOUBLE-STRANDED; DNA END-JOINING REPAIR; DNA LIGASES; DNA REPAIR ENZYMES; DNA-ACTIVATED PROTEIN KINASE; DNA-BINDING PROTEINS; HUMANS; NUCLEAR PROTEINS; PHOSPHORYLATION;

MLCS; MLOWN;

EID: 84880615973     PISSN: 03603016     EISSN: 1879355X     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2013.01.011     Document Type: Article

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