Visualization of DNA-induced conformational changes in the DNA repair kinase DNA-PKcs

EMBO Journal

Volumn 22, Issue 21, 2003, Pages 5875-5882

  Boskovic, Jasminka ^a   Rivera Calzada, Angel ^a   Maman, Joseph D ^b   Chacón, Pablo ^a   Willison, Keith R ^b   Pearl, Laurence H ^b   Llorca, Oscar ^c  

^a UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

^b INSTITUTE OF CANCER RESEARCH   (United Kingdom)

^c NONE

Author keywords

DNA repair; DNA PK; Electron microscopy; NHEJ

Indexed keywords

DIMER; DNA; DNA DEPENDENT PROTEIN KINASE; DOUBLE STRANDED DNA; SINGLE STRANDED DNA;

ARTICLE; BINDING AFFINITY; COMPLEX FORMATION; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CORRELATION ANALYSIS; DNA DAMAGE; DNA REPAIR; DNA STRAND BREAKAGE; ELECTRON MICROSCOPY; ENZYME ACTIVATION; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME ASSAY; ENZYME BINDING; ENZYME PURIFICATION; ENZYME STRUCTURE; GENETIC RECOMBINATION; HUMAN; IMAGE RECONSTRUCTION; MOLECULAR INTERACTION; MOLECULAR RECOGNITION; NON HOMOLOGOUS END JOINING; PRIORITY JOURNAL; PROTEIN DNA BINDING; PROTEIN DOMAIN; STRUCTURE ANALYSIS; THREE DIMENSIONAL IMAGING;

BASE SEQUENCE; CELL CYCLE PROTEINS; DNA; DNA DAMAGE; DNA REPAIR; DNA-ACTIVATED PROTEIN KINASE; DNA-BINDING PROTEINS; ENZYME ACTIVATION; HELA CELLS; HUMANS; MICROSCOPY, ELECTRON; MODELS, BIOLOGICAL; MODELS, MOLECULAR; NUCLEAR PROTEINS; PROTEIN CONFORMATION; PROTEIN SUBUNITS; PROTEIN-SERINE-THREONINE KINASES; TUMOR SUPPRESSOR PROTEINS;

EID: 0242576857     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/cdg555     Document Type: Article

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