Crystal structure of DNA-PKcs reveals a large open-ring cradle comprised of HEAT repeats

Nature

Volumn 463, Issue 7277, 2010, Pages 118-121

  Sibanda, Bancinyane L ^a   Chirgadze, Dimitri Y ^a   Blundell, Tom L ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CARBOXY TERMINAL KINASE; DNA DEPENDENT PROTEIN KINASE; HELIX LOOP HELIX PROTEIN; PHOSPHOTRANSFERASE; POLYPEPTIDE; UNCLASSIFIED DRUG;

AMINO ACID; CANCER; CHROMOSOME; CRYSTAL STRUCTURE; DNA; ENZYME ACTIVITY; GENOME; MAMMAL; METABOLISM;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CRYSTAL STRUCTURE; DNA REPAIR; DOUBLE STRANDED DNA BREAK; ENZYME STRUCTURE; FEMALE; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN DNA BINDING; PROTEIN DOMAIN; PROTEIN FOLDING;

ANTIGENS, NUCLEAR; CATALYTIC DOMAIN; CRYSTALLOGRAPHY, X-RAY; DNA; DNA BREAKS, DOUBLE-STRANDED; DNA-ACTIVATED PROTEIN KINASE; DNA-BINDING PROTEINS; HELA CELLS; HELIX-TURN-HELIX MOTIFS; HUMANS; MODELS, MOLECULAR; NUCLEAR PROTEINS; PROTEIN FOLDING; PROTEIN STRUCTURE, SECONDARY;

MAMMALIA;

EID: 73849140503     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature08648     Document Type: Article

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