Inhibition of homologous recombination by DNA-dependent protein kinase requires kinase activity, is titratable, and is modulated by autophosphorylation

Molecular and Cellular Biology

Volumn 31, Issue 8, 2011, Pages 1719-1733

  Neal, Jessica A ^a   Dang, Van ^a   Douglas, Pauline ^b   Wold, Marc S ^c   Lees Miller, Susan P ^b   Meek, Katheryn ^a  

^a Department of Pathobiology and Diagnostic Investigation Michigan State University ^*  (United States)

^b UNIVERSITY OF CALGARY   (Canada)

^c UNIVERSITY OF IOWA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; DNA DEPENDENT PROTEIN KINASE; PROTEIN SUBUNIT; XRCC4 PROTEIN;

ANIMAL CELL; ARTICLE; AUTOPHOSPHORYLATION; CATALYSIS; CHO CELL; COMPETITIVE INHIBITION; CONTROLLED STUDY; DNA DETERMINATION; DNA REPAIR; DOUBLE STRANDED DNA BREAK; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME SUBSTRATE; FEMALE; GENE MAPPING; GENETIC RECOMBINATION; HOMOLOGOUS RECOMBINATION; HUMAN; HUMAN CELL; NONHOMOLOGOUS END JOINING; NONHUMAN; OPEN READING FRAME; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; RADIOSENSITIVITY;

AMINO ACID SEQUENCE; ANIMALS; BIOCATALYSIS; CATALYTIC DOMAIN; CELL LINE; DNA BREAKS, DOUBLE-STRANDED; DNA-ACTIVATED PROTEIN KINASE; ENZYME ACTIVATION; HUMANS; MOLECULAR SEQUENCE DATA; MUTATION; PHOSPHORYLATION; RECOMBINANT PROTEINS; SEQUENCE ALIGNMENT;

EID: 79953134635     PISSN: 02707306     EISSN: 10985549     Source Type: Journal    
DOI: 10.1128/MCB.01298-10     Document Type: Article

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