Congenital bone marrow failure in DNA-PKcs mutant mice associated with deficiencies in DNA repair

Journal of Cell Biology

Volumn 193, Issue 2, 2011, Pages 295-305

  Zhang, Shichuan ^a   Yajima, Hirohiko ^a   Huynh, HoangDinh ^a   Zheng, Junke ^a   Callen, Elsa ^b   Chen, Hua Tang ^b   Wong, Nancy ^b   Bunting, Samuel ^b   Lin, Yu Fen ^a   Li, Mengxia ^a   Lee, Kyung Jone ^a   Story, Michael ^a   Gapud, Eric ^c   Sleckman, Barry P ^c   Nussenzweig, André ^b   Zhang, Cheng Cheng ^a   Chen, David J ^a   Chen, Benjamin P C ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

^c WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; CROSS LINKING REAGENT; DNA DEPENDENT PROTEIN KINASE; PROTEIN P53;

ALLELE; AMINO ACID SUBSTITUTION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; BONE MARROW DEPRESSION; CELL PROLIFERATION; CONTROLLED STUDY; DISORDERS OF DNA SYNTHESIS AND REPAIR; DNA DAMAGE; EMBRYO; EMBRYO CELL; ENZYME ACTIVE SITE; FANCONI ANEMIA; GENOTOXICITY; HEMATOPOIETIC STEM CELL; HOMOLOGOUS RECOMBINATION; HYPERPIGMENTATION; INTESTINE CRYPT; KNOCKOUT MOUSE; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; APOPTOSIS; CELLS, CULTURED; CROSS-LINKING REAGENTS; DNA DAMAGE; DNA REPAIR; DNA-ACTIVATED PROTEIN KINASE; DNA-BINDING PROTEINS; FANCONI ANEMIA; FIBROBLASTS; GENE KNOCK-IN TECHNIQUES; HEMATOPOIESIS; HEMATOPOIETIC STEM CELLS; HYPERPIGMENTATION; MICE; MICE, KNOCKOUT; MUTATION; NUCLEAR PROTEINS; RECOMBINATION, GENETIC; TUMOR SUPPRESSOR PROTEIN P53;

MUS;

EID: 79955519714     PISSN: 00219525     EISSN: 00219525     Source Type: Journal    
DOI: 10.1083/jcb.201009074     Document Type: Article

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