Heat shock protein 90α (Hsp90α) is phosphorylated in response to DNA damage and accumulates in repair foci

Journal of Biological Chemistry

Volumn 287, Issue 12, 2012, Pages 8803-8815

  Quanz, Maria ^a,b   Herbette, Aurélie ^b   Sayarath, Mano ^b   De Koning, Leanne ^c   Dubois, Thierry ^c   Sun, Jian Sheng ^b,d   Dutreix, Marie ^a  

^a Centre National de la Recherche Scientifique   (France)

^b DNA Therapeutics   (France)

^c INSTITUT CURIE   (France)

^d MUSÉUM NATIONAL D'HISTOIRE NATURELLE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

BASAL LEVELS; DNA DAMAGES; DNA DOUBLE STRAND BREAKS; DNA-DEPENDENT PROTEIN KINASE; DNA-REPAIR ENZYMES; DOUBLE-STRANDED DNA MOLECULE; HEAT SHOCK PROTEIN; IN-VIVO; MOLECULAR CHAPERONES; NONHOMOLOGOUS END JOINING; PHOSPHATIDYLINOSITOL; PHOSPHORYLATED HISTONE; PROTEIN ARRAYS; REVERSE PHASE; SIGNALING CASCADES; SIGNALING PATHWAYS;

AMINO ACIDS; CELLS; CYTOLOGY; ENZYMES; PHOSPHORYLATION; PROTEINS; REPAIR;

DNA;

CHAPERONE; DNA DEPENDENT PROTEIN KINASE; DOUBLE STRANDED DNA; HEAT SHOCK PROTEIN 90; HEAT SHOCK PROTEIN 90 ALPHA; HISTONE H2AX; PHOSPHATIDYLINOSITOL 3 KINASE; THREONINE; THREONINE 7; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; CYTOPLASM; DNA DAMAGE; DNA END JOINING REPAIR; DNA STRAND BREAKAGE; FEMALE; HUMAN; HUMAN CELL; IN VIVO STUDY; INTRACELLULAR SIGNALING; KINETICS; MALIGNANT NEOPLASTIC DISEASE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN CROSS LINKING; PROTEIN DATABASE; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN MICROARRAY; PROTEIN PHOSPHORYLATION; PROTEIN TARGETING; REVERSE PHASE PROTEIN MICROARRAY;

AMINO ACID MOTIFS; ANIMALS; CELL LINE, TUMOR; DNA DAMAGE; DNA REPAIR; FEMALE; HSP90 HEAT-SHOCK PROTEINS; HUMANS; MICE; MICE, NUDE; PHOSPHORYLATION; RATS;

EID: 84863371816     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.320887     Document Type: Article

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