The DNA-dependent protein kinase is inactivated by autophosphorylation of the catalytic subunit

Journal of Biological Chemistry

Volumn 271, Issue 15, 1996, Pages 8936-8941

  Chan, Doug W ^a   Lees Miller, Susan P ^a  

^a UNIVERSITY OF CALGARY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

DOUBLE STRANDED DNA; PROTEIN KINASE; PROTEIN SERINE THREONINE KINASE;

ARTICLE; AUTOPHOSPHORYLATION; CONTROLLED STUDY; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME INACTIVATION; ENZYME PHOSPHORYLATION; HUMAN; HUMAN TISSUE; PLACENTA; PRIORITY JOURNAL;

ADENOSINE TRIPHOSPHATE; ANTIGENS, NUCLEAR; BASE SEQUENCE; DNA; DNA HELICASES; DNA-ACTIVATED PROTEIN KINASE; DNA-BINDING PROTEINS; ENZYME ACTIVATION; HUMANS; MACROMOLECULAR SUBSTANCES; MOLECULAR SEQUENCE DATA; NUCLEAR PROTEINS; PEPTIDES; PHOSPHORYLATION; PLACENTA; PROTEIN BINDING; PROTEIN-SERINE-THREONINE KINASES;

EID: 0030009738     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.271.15.8936     Document Type: Article

References (46)

1. Anderson, C. W., and Lees-Miller, S. P. (1992) Crit. Rev. Eukaryot Gene Exp 2, 283-314
2. Carter, T , Vančurová, I., Sun, I , Lou, W., and DeLeon, S. (1990) Mol. Cell. Biol 10, 6460-6471
3. Lees-Miller, S. P., Chen, Y.-R., and Anderson, C. W. (1990) Mol. Cell. Biol. 10, 6472-6481
4. Hartley, K O , Gell, D., Smith, G. C. M., Zhang, H., Divecha, N , Connelly, M. A , Admon, A., Lees-Miller, S. P., Anderson, C. W., and Jackson, S. P. (1995) Cell 82, 849-856
5. Dvir, A., Peterson, S. R., Knuth, M. W., Lu, H., and Dynan, W. S (1992) Proc. Natl. Acad. Sci. U. S. A. 89, 11920-11924
6. Gottlieb, T. M., and Jackson, S. P. (1993) Cell 72, 131-142
7. Morozov, V. E., Falzon, M., Anderson, C W , and Kuff, E. L. (1994) J Biol Chem. 269, 16684-16688
8. Anderson, C. W. (1993) Trends Biochem. Sci. 18, 433-437
9. Anderson, C. W. (1994) Semin. Cell Biol. 5, 427-436
10. Gottleib, T. M., and Jackson, S. P. (1994) Trends Biochem. Sci. 19, 500-508
11. Getts, R C., and Stamato, T. D. (1994) J. Biol Chem. 269, 15981-15984
12. Rathmell, W. K., and Chu, G. (1994) Mol. Cell Biol. 14, 4741-4748
13. Rathmell, W. K., and Chu, G. (1994) Proc. Natl. Acad. Sci U. S. A. 91, 7623-7627
14. Smider, V., Rathmell, W. K., Leiber, M. R., and Chu, G. (1994) Science 266, 288-291
15. Taccioli, G. E., Gottlieb, T. M., Blunt, T., Priestly, A , Demengeot, J , Mizuta, R., Lehman, A. R., Alt, F. W., Jackson, S. P , and Jeggo, P. A. (1994) Science 265, 1442-1445
16. Boubnov, N. V., Hall, K T., Wills, Z , Lee, S. E., He, D. M., Benjamin, D. M., Pulaski, C. R., Band, H , Reeves, W., Hendrickson, E. A., and Weaver, D. T. (1995) Proc. Natl. Acad. Sci. U. S. A. 92, 890-894
17. Kirchgessner, C , Patil, C. K., Evans, J. W., Cuomo, C A., Fried, L. M., Carter, T , Oettinger, M. A., and Brown, J. M. (1995) Science 267, 1178-1183
18. Blunt, T., Finnie, N. J., Tacciolo, G., Smith, G. C. M., Demengot, J., Gottlieb, T M , Mizuta, R., Varghese, A. J., Alt, F. W., Jeggo, P. A., and Jackson, S. P (1995) Cell 80, 813-823
19. Peterson, S. R., Kurimasa, A., Oshimura, M., Dynan, W. S., Bradbury, E. M., and Chen, D. (1995) Proc. Natl Acad. Sci. U. S. A. 92, 3171-3174
20. Lees-Miller, S. P., Godbout, R., Chan, D. W., Weinfeld, M. W., Day, R. S., III, Barron, G. M., and Allalums-Turner, J (1995) Science 267, 1183-1185
21. Sipley, J. D., Menninger, J., Hartley, K. O., Ward, D. C., Jackson, S. P., and Anderson, C. W. (1995) Proc. Natl. Acad. Sci. U. S. A. 92, 7515-7519
22. Lees-Miller, S. P., Sakaguchi, K., Ullrich, S., Appella, E , and Anderson, C. W. (1992) Mol. Cell. Biol. 12, 5041-5049
23. Jackson, S. P., MacDonald, J. J., Lees-Miller, S., and Tjian, R. (1990) Cell 63, 155-165
24. Abate, C., Baker, S. J., Lees-Miller, S. P., Anderson, C. W., Marshak, D. R., and Curran, T. (1993) Proc. Natl. Acad. Sci. U. S. A. 90, 6766-6770
25. Bannister, A. J., Gottlieb, T. M , Kouzarides, T., and Jackson, S P. (1993) Nucleic Acids Res. 21, 1289-1295
26. Iijima, S., Teraoka, H., Date, T., and Tsukada, K (1992) Eur J Biochem. 206, 595-603
27. Liu, S.-H., Ma, J. T., Yueh, A. Y., Lees-Miller, S. P., Anderson, C. W , and Ng, S.-Y. (1993) J. Biol. Chem. 268, 21147-21154
28. Anderson, C. W., Connelly, M. A., Lees-Miller, S. P , Lintott, L. G., Zhang, H., Sipley, J. A., Sakaguchi, K., and Appella, E. (1995) Methods in Protein Structure Analysis (Atassi, M Z., ed) Chapter 35, pp. 395-406, Plenum Press, New York
29. Roberts, M. R., Han, Y., Fienberg, A., Hunihan, L., and Ruddle, F. H. (1994) Proc. Natl. Acad. Sci. U. S. A. 91, 6354-6458
30. Kim, D., Ouyang, H., Yang, S.-H., Nussenzweig, A., Burgman, P., and Li, G. C. (1995) J Biol Chem. 270, 15277-15284
31. Li, G. C., Yang, S.-H., Kim, D., Nussenzweig, A., Ouyang, H., Wei, J., Burgman, P., and Li, L. (1995) Proc. Natl. Acad. Sci. U. S. A. 92, 4512-4516
32. Genersch, E., Eekerson, C., Lottspeich, F., Herzog, C., Kuhn, K., and Poschl, E. (1995) EMBO J. 14, 791-800
33. Peterson, S. R., Jesch, S. A., Chamberlin, T. N., Dvir, A., Rabindran, S. K., Wu, C., and Dynan, W. S. (1995) J. Biol. Chem. 270, 1449-1454
34. Hoff, C. M., Ghosh, A. K., Prabhakar, B S., and Jacob, S. T. (1994) Proc. Natl. Acad. Sci. U S. A. 91, 762-766
35. Kuhn, A., Gottlieb, T. M., Jackson, S P , and Grimmt, I. (1995) Genes & Dev. 9, 193-203
36. Labhart, P. (1995) Proc. Natl. Acad. Sci. U. S. A. 92, 2934-2938
37. Tuteja, N., Tuteja, R., Ochem, A., Taneja, P., Huang, N W., Simoncsits, A., Susic, S., Rahman, K., Marusic, L., Chen, J., Zhang, J., Wang, S., Pongor, S., and Falaschi, A. (1994) EMBO J. 13, 4991-5001
38. Cao, Q.-P., Pitt, S., Leszyck, J., and Baril, E. F. (1994) Biochemistry 33, 6354-6357
39. Chan, D. W., Mody, C. H , Ting, N. S. Y., and Lees-Miller, S. P. (1995) Biochem. Cell Biol., in press
40. Boyle, W. J., van der Geer, P., and Hunter, T. (1991) Methods Enzymol. 201, 101-149
41. Allaway, G. P., Vivino, A. A , Kohn, L. D., Notkins, A. L., and Prabhakar, B. S. (1990) Biochem Biophys. Res Commun. 168, 747-755
42. Suwa, A., Hirakata, M., Takeda, Y., Jesch, S. A., Mimori, T., and Hardin, J. A. (1994) Proc Natl. Acad. Sci. U. S. A. 91, 6904-6908
43. Mimori, T., and Hardin, J. A (1986) J. Biol Chem. 261, 10375-10379
44. Roth, D. B., Lindahl, T., and Gellert, M. (1995) Curr. Biol. 5, 496-499
45. Chan, J. Y. C., Lerman, M. I., Prabhakar, B. S., Isozaki, O , Santisteban, P., Kuppers, R. C., Oates, E L., Notkins, A. L., and Kohn, L. D. (1989) J. Biol. Chem 264, 3651-3654
46. Mimori, T., Ohosone, Y., Hama, N., Suwa, A., Akizuki, M., Homma, M., Griffith, A. J., and Hardin, J. A. (1990) Proc Natl. Acad. Sci. U. S A. 87, 1777-1781