Artemis C-terminal region facilitates V(D)J recombination through its interactions with DNA Ligase IV and DNA-pkcs

Journal of Experimental Medicine

Volumn 209, Issue 5, 2012, Pages 955-963

  Malu, Shruti ^a,f   De Ioannes, Pablo ^a   Kozlov, Mikhail ^a   Greene, Marsha ^a   Francis, Dailia ^a   Hanna, Mary ^a   Pena, Jesse ^a   Escalante, Carlos R ^a,g   Kurosawa, Aya ^b   Erdjument Bromage, Hediye ^c   Tempst, Paul ^c   Adachi, Noritaka ^b   Vezzoni, Paolo ^d,e   Villa, Anna ^d,e   Aggarwal, Aneel K ^a   Cortes, Patricia ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^b YOKOHAMA CITY UNIVERSITY   (Japan)

^c MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^d Milan Unit   (Italy)

^e HUMANITAS CLINICAL AND RESEARCH CENTER   (Italy)

^f UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^g VIRGINIA COMMONWEALTH UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ENDONUCLEASE; GLUTATHIONE TRANSFERASE; POLYDEOXYRIBONUCLEOTIDE SYNTHASE; PROTEIN ARTEMIS; PROTEIN KINASE; UNCLASSIFIED DRUG; XRCC4 PROTEIN; DCLRE1C PROTEIN, HUMAN; DNA BINDING PROTEIN; DNA DEPENDENT PROTEIN KINASE; NUCLEAR PROTEIN; POLYDEOXYRIBONUCLEOTIDE SYNTHASE (ATP); PRIMER DNA; PRKDC PROTEIN, HUMAN; XRCC4 PROTEIN, HUMAN;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CATALYSIS; CONTROLLED STUDY; DNA REPAIR; GLIOBLASTOMA; HUMAN; HUMAN CELL; IN VITRO STUDY; MASS SPECTROMETRY; MUTATIONAL ANALYSIS; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; SEQUENCE ANALYSIS; SIGNAL TRANSDUCTION; STRUCTURE ANALYSIS; VDJ RECOMBINATION; AMINO ACID SEQUENCE; DNA SEQUENCE; FLUORESCENCE POLARIZATION; GENE VECTOR; GENETIC TRANSFECTION; GENETICS; HELA CELL; IMMUNOPRECIPITATION; METABOLISM; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; PHOSPHORYLATION; PHYSIOLOGY;

AMINO ACID SEQUENCE; BASE SEQUENCE; DNA LIGASES; DNA PRIMERS; DNA REPAIR; DNA-ACTIVATED PROTEIN KINASE; DNA-BINDING PROTEINS; FLUORESCENCE POLARIZATION; GENETIC VECTORS; HELA CELLS; HUMANS; IMMUNOPRECIPITATION; MOLECULAR SEQUENCE DATA; NUCLEAR PROTEINS; PHOSPHORYLATION; POINT MUTATION; SEQUENCE ANALYSIS, DNA; TRANSFECTION; V(D)J RECOMBINATION;

EID: 84863798398     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.20111437     Document Type: Article

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