APLF (C2orf13) facilitates nonhomologous end-joining and undergoes ATM-dependent hyperphosphorylation following ionizing radiation

DNA Repair

Volumn 7, Issue 2, 2008, Pages 292-302

  Macrae, Chloe J ^a,b   McCulloch, Richard D ^a   Ylanko, Jarkko ^c,d   Durocher, Daniel ^c,d   Koch, C Anne ^a,b  

^a PRINCESS MARGARET HOSPITAL   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c MOUNT SINAI HOSPITAL   (Canada)

^d UNIVERSITY OF TORONTO   (Canada)

Author keywords

APLF; ATM; CK2; FHA domains; NHEJ; Phosphorylation

Indexed keywords

APRATAXIN AND PNK LIKE FACTOR; ATM PROTEIN; ENDONUCLEASE; EXONUCLEASE; HETERODIMER; KU ANTIGEN; POLYDEOXYRIBONUCLEOTIDE SYNTHASE; SERINE; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; ZINC FINGER PROTEIN;

ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; DNA DAMAGE; DNA REPAIR; DOUBLE STRANDED DNA BREAK; HUMAN; HUMAN CELL; IONIZING RADIATION; MOLECULAR RECOGNITION; NONHOMOLOGOUS END JOINING; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; SEQUENCE HOMOLOGY;

AMINO ACID SEQUENCE; BASE SEQUENCE; CELL CYCLE PROTEINS; CELL LINE; DNA BREAKS, DOUBLE-STRANDED; DNA HELICASES; DNA REPAIR; DNA-BINDING PROTEINS; ELECTROPHORETIC MOBILITY SHIFT ASSAY; HUMANS; IMMUNOBLOTTING; IMMUNOPRECIPITATION; MICROSCOPY, FLUORESCENCE; MOLECULAR SEQUENCE DATA; PHOSPHOPROTEINS; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; SEQUENCE ALIGNMENT; SEQUENCE ANALYSIS, DNA; TUMOR SUPPRESSOR PROTEINS;

MAMMALIA;

EID: 37549023517     PISSN: 15687864     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.dnarep.2007.10.008     Document Type: Article

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