-
1
-
-
33748138991
-
Roles of nonhomologous DNA end joining, V(D)J recombination, and class switch recombination in chromosomal translocations
-
Lieber M.R., Yu K., and Raghavan S.C. Roles of nonhomologous DNA end joining, V(D)J recombination, and class switch recombination in chromosomal translocations. DNA Repair (Amst.) 5 (2006) 1234-1245
-
(2006)
DNA Repair (Amst.)
, vol.5
, pp. 1234-1245
-
-
Lieber, M.R.1
Yu, K.2
Raghavan, S.C.3
-
2
-
-
19344370467
-
Mechanism of DNA double-strand break repair by non-homologous end joining
-
Hefferin M.L., and Tomkinson A.E. Mechanism of DNA double-strand break repair by non-homologous end joining. DNA Repair (Amst.) 4 (2005) 639-648
-
(2005)
DNA Repair (Amst.)
, vol.4
, pp. 639-648
-
-
Hefferin, M.L.1
Tomkinson, A.E.2
-
3
-
-
0942268167
-
Repair of DNA double strand breaks by non-homologous end joining
-
Lees-Miller S.P., and Meek K. Repair of DNA double strand breaks by non-homologous end joining. Biochimie 85 (2003) 1161-1173
-
(2003)
Biochimie
, vol.85
, pp. 1161-1173
-
-
Lees-Miller, S.P.1
Meek, K.2
-
4
-
-
38049125555
-
The endless tale of non-homologous end-joining
-
Weterings E., and Chen D.J. The endless tale of non-homologous end-joining. Cell Res. 18 (2008) 114-124
-
(2008)
Cell Res.
, vol.18
, pp. 114-124
-
-
Weterings, E.1
Chen, D.J.2
-
5
-
-
31044432090
-
XLF interacts with the XRCC4-DNA ligase IV complex to promote DNA nonhomologous end-joining
-
Ahnesorg P., Smith P., and Jackson S.P. XLF interacts with the XRCC4-DNA ligase IV complex to promote DNA nonhomologous end-joining. Cell 124 (2006) 301-313
-
(2006)
Cell
, vol.124
, pp. 301-313
-
-
Ahnesorg, P.1
Smith, P.2
Jackson, S.P.3
-
6
-
-
31044440630
-
Cernunnos, a novel nonhomologous end-joining factor, is mutated in human immunodeficiency with microcephaly
-
Buck D., Malivert L., de Chasseval R., Barraud A., Fondaneche M.C., Sanal O., Plebani A., Stephan J.L., Hufnagel M., le Deist F., Fischer A., Durandy A., de Villartay J.P., and Revy P. Cernunnos, a novel nonhomologous end-joining factor, is mutated in human immunodeficiency with microcephaly. Cell 124 (2006) 287-299
-
(2006)
Cell
, vol.124
, pp. 287-299
-
-
Buck, D.1
Malivert, L.2
de Chasseval, R.3
Barraud, A.4
Fondaneche, M.C.5
Sanal, O.6
Plebani, A.7
Stephan, J.L.8
Hufnagel, M.9
le Deist, F.10
Fischer, A.11
Durandy, A.12
de Villartay, J.P.13
Revy, P.14
-
7
-
-
31044446441
-
DNA double-strand break repair: a relentless hunt uncovers new prey
-
Sekiguchi J.M., and Ferguson D.O. DNA double-strand break repair: a relentless hunt uncovers new prey. Cell 124 (2006) 260-262
-
(2006)
Cell
, vol.124
, pp. 260-262
-
-
Sekiguchi, J.M.1
Ferguson, D.O.2
-
8
-
-
37349113779
-
Crystal structure of human XLF: a twist in nonhomologous DNA end-joining
-
Andres S.N., Modesti M., Tsai C.J., Chu G., and Junop M.S. Crystal structure of human XLF: a twist in nonhomologous DNA end-joining. Mol. Cell 28 (2007) 1093-1101
-
(2007)
Mol. Cell
, vol.28
, pp. 1093-1101
-
-
Andres, S.N.1
Modesti, M.2
Tsai, C.J.3
Chu, G.4
Junop, M.S.5
-
9
-
-
38049034405
-
Crystal structure of human XLF/Cernunnos reveals unexpected differences from XRCC4 with implications for NHEJ
-
Li Y., Chirgadze D.Y., Bolanos-Garcia V.M., Sibanda B.L., Davies O.R., Ahnesorg P., Jackson S.P., and Blundell T.L. Crystal structure of human XLF/Cernunnos reveals unexpected differences from XRCC4 with implications for NHEJ. EMBO J. 27 (2007) 290-300
-
(2007)
EMBO J.
, vol.27
, pp. 290-300
-
-
Li, Y.1
Chirgadze, D.Y.2
Bolanos-Garcia, V.M.3
Sibanda, B.L.4
Davies, O.R.5
Ahnesorg, P.6
Jackson, S.P.7
Blundell, T.L.8
-
10
-
-
34248400443
-
Defective DNA repair and increased genomic instability in Cernunnos-XLF-deficient murine ES cells
-
Zha S., Alt F.W., Cheng H.L., Brush J.W., and Li G. Defective DNA repair and increased genomic instability in Cernunnos-XLF-deficient murine ES cells. Proc. Natl. Acad. Sci. U.S.A. 104 (2007) 4518-4523
-
(2007)
Proc. Natl. Acad. Sci. U.S.A.
, vol.104
, pp. 4518-4523
-
-
Zha, S.1
Alt, F.W.2
Cheng, H.L.3
Brush, J.W.4
Li, G.5
-
11
-
-
34249938518
-
Cernunnos/XLF promotes the ligation of mismatched and noncohesive DNA ends
-
Tsai C.J., Kim S.A., and Chu G. Cernunnos/XLF promotes the ligation of mismatched and noncohesive DNA ends. Proc. Natl. Acad. Sci. U.S.A. 104 (2007) 7851-7856
-
(2007)
Proc. Natl. Acad. Sci. U.S.A.
, vol.104
, pp. 7851-7856
-
-
Tsai, C.J.1
Kim, S.A.2
Chu, G.3
-
12
-
-
34249685474
-
Length-dependent binding of human XLF to DNA and stimulation of XRCC4.DNA ligase IV activity
-
Lu H., Pannicke U., Schwarz K., and Lieber M.R. Length-dependent binding of human XLF to DNA and stimulation of XRCC4.DNA ligase IV activity. J. Biol. Chem. 282 (2007) 11155-11162
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 11155-11162
-
-
Lu, H.1
Pannicke, U.2
Schwarz, K.3
Lieber, M.R.4
-
13
-
-
3242882820
-
PI 3-kinase related kinases: 'big' players in stress-induced signaling pathways
-
Abraham R.T. PI 3-kinase related kinases: 'big' players in stress-induced signaling pathways. DNA Repair (Amst.) 3 (2004) 883-887
-
(2004)
DNA Repair (Amst.)
, vol.3
, pp. 883-887
-
-
Abraham, R.T.1
-
14
-
-
0034662228
-
Both V(D)J recombination and radioresistance require DNA-PK kinase activity, though minimal levels suffice for V(D)J recombination
-
Kienker L.J., Shin E.K., and Meek K. Both V(D)J recombination and radioresistance require DNA-PK kinase activity, though minimal levels suffice for V(D)J recombination. Nucleic Acids Res. 28 (2000) 2752-2761
-
(2000)
Nucleic Acids Res.
, vol.28
, pp. 2752-2761
-
-
Kienker, L.J.1
Shin, E.K.2
Meek, K.3
-
15
-
-
0032938747
-
Requirement for the kinase activity of human DNA-dependent protein kinase catalytic subunit in DNA strand break rejoining
-
Kurimasa A., Kumano S., Boubnov N.V., Story M.D., Tung C.S., Peterson S.R., and Chen D.J. Requirement for the kinase activity of human DNA-dependent protein kinase catalytic subunit in DNA strand break rejoining. Mol. Cell Biol. 19 (1999) 3877-3884
-
(1999)
Mol. Cell Biol.
, vol.19
, pp. 3877-3884
-
-
Kurimasa, A.1
Kumano, S.2
Boubnov, N.V.3
Story, M.D.4
Tung, C.S.5
Peterson, S.R.6
Chen, D.J.7
-
16
-
-
33744924482
-
Preclinical evaluation of a potent novel DNA-dependent protein kinase inhibitor NU7441
-
Zhao Y., Thomas H.D., Batey M.A., Cowell I.G., Richardson C.J., Griffin R.J., Calvert A.H., Newell D.R., Smith G.C., and Curtin N.J. Preclinical evaluation of a potent novel DNA-dependent protein kinase inhibitor NU7441. Cancer Res. 66 (2006) 5354-5362
-
(2006)
Cancer Res.
, vol.66
, pp. 5354-5362
-
-
Zhao, Y.1
Thomas, H.D.2
Batey, M.A.3
Cowell, I.G.4
Richardson, C.J.5
Griffin, R.J.6
Calvert, A.H.7
Newell, D.R.8
Smith, G.C.9
Curtin, N.J.10
-
17
-
-
22044445683
-
DNA-PK-dependent phosphorylation of Ku70/80 is not required for non-homologous end joining
-
Douglas P., Gupta S., Morrice N., Meek K., and Lees-Miller S.P. DNA-PK-dependent phosphorylation of Ku70/80 is not required for non-homologous end joining. DNA Repair (Amst.) 4 (2005) 1006-1018
-
(2005)
DNA Repair (Amst.)
, vol.4
, pp. 1006-1018
-
-
Douglas, P.1
Gupta, S.2
Morrice, N.3
Meek, K.4
Lees-Miller, S.P.5
-
18
-
-
0242268028
-
DNA-PK phosphorylation sites in XRCC4 are not required for survival after radiation or for V(D)J recombination
-
Yu Y., Wang W., Ding Q., Ye R., Chen D., Merkle D., Schriemer D., Meek K., and Lees-Miller S.P. DNA-PK phosphorylation sites in XRCC4 are not required for survival after radiation or for V(D)J recombination. DNA Repair (Amst.) 2 (2003) 1239-1252
-
(2003)
DNA Repair (Amst.)
, vol.2
, pp. 1239-1252
-
-
Yu, Y.1
Wang, W.2
Ding, Q.3
Ye, R.4
Chen, D.5
Merkle, D.6
Schriemer, D.7
Meek, K.8
Lees-Miller, S.P.9
-
19
-
-
0842346435
-
Identification of DNA-PKcs phosphorylation sites in XRCC4 and effects of mutations at these sites on DNA end joining in a cell-free system
-
Lee K.J., Jovanovic M., Udayakumar D., Bladen C.L., and Dynan W.S. Identification of DNA-PKcs phosphorylation sites in XRCC4 and effects of mutations at these sites on DNA end joining in a cell-free system. DNA Repair (Amst.) 3 (2004) 267-276
-
(2004)
DNA Repair (Amst.)
, vol.3
, pp. 267-276
-
-
Lee, K.J.1
Jovanovic, M.2
Udayakumar, D.3
Bladen, C.L.4
Dynan, W.S.5
-
20
-
-
35548969432
-
DNA-dependent protein kinase in nonhomologous end joining: a lock with multiple keys?
-
Weterings E., and Chen D.J. DNA-dependent protein kinase in nonhomologous end joining: a lock with multiple keys?. J. Cell Biol. 179 (2007) 183-186
-
(2007)
J. Cell Biol.
, vol.179
, pp. 183-186
-
-
Weterings, E.1
Chen, D.J.2
-
21
-
-
37849018404
-
Ku recruits XLF to DNA double-strand breaks
-
Yano K., Morotomi-Yano K., Wang S.Y., Uematsu N., Lee K.J., Asaithamby A., Weterings E., and Chen D.J. Ku recruits XLF to DNA double-strand breaks. EMBO Rep. 9 (2008) 91-96
-
(2008)
EMBO Rep.
, vol.9
, pp. 91-96
-
-
Yano, K.1
Morotomi-Yano, K.2
Wang, S.Y.3
Uematsu, N.4
Lee, K.J.5
Asaithamby, A.6
Weterings, E.7
Chen, D.J.8
-
22
-
-
0345505218
-
Nonhomologous end joining and V(D)J recombination require an additional factor
-
Dai Y., Kysela B., Hanakahi L.A., Manolis K., Riballo E., Stumm M., Harville T.O., West S.C., Oettinger M.A., and Jeggo P.A. Nonhomologous end joining and V(D)J recombination require an additional factor. Proc. Natl. Acad. Sci. U.S.A. 100 (2003) 2462-2467
-
(2003)
Proc. Natl. Acad. Sci. U.S.A.
, vol.100
, pp. 2462-2467
-
-
Dai, Y.1
Kysela, B.2
Hanakahi, L.A.3
Manolis, K.4
Riballo, E.5
Stumm, M.6
Harville, T.O.7
West, S.C.8
Oettinger, M.A.9
Jeggo, P.A.10
-
23
-
-
33846088785
-
The non-homologous end-joining protein Nej1p is a target of the DNA damage checkpoint
-
Ahnesorg P., and Jackson S.P. The non-homologous end-joining protein Nej1p is a target of the DNA damage checkpoint. DNA Repair (Amst.) 6 (2007) 190-201
-
(2007)
DNA Repair (Amst.)
, vol.6
, pp. 190-201
-
-
Ahnesorg, P.1
Jackson, S.P.2
-
24
-
-
2642543876
-
Biochemical characterization of the ataxia-telangiectasia mutated (ATM) protein from human cells
-
Goodarzi A.A., and Lees-Miller S.P. Biochemical characterization of the ataxia-telangiectasia mutated (ATM) protein from human cells. DNA Repair (Amst.) 3 (2004) 753-767
-
(2004)
DNA Repair (Amst.)
, vol.3
, pp. 753-767
-
-
Goodarzi, A.A.1
Lees-Miller, S.P.2
-
25
-
-
0942276226
-
Mining biomarkers in human sera using proteomic tools
-
Zhang R., Barker L., Pinchev D., Marshall J., Rasamoelisolo M., Smith C., Kupchak P., Kireeva I., Ingratta L., and Jackowski G. Mining biomarkers in human sera using proteomic tools. Proteomics 4 (2004) 244-256
-
(2004)
Proteomics
, vol.4
, pp. 244-256
-
-
Zhang, R.1
Barker, L.2
Pinchev, D.3
Marshall, J.4
Rasamoelisolo, M.5
Smith, C.6
Kupchak, P.7
Kireeva, I.8
Ingratta, L.9
Jackowski, G.10
-
26
-
-
0031914976
-
DNA-dependent protein kinase interacts with antigen receptor response element binding proteins NF90 and NF45
-
Ting N.S., Kao P.N., Chan D.W., Lintott L.G., and Lees-Miller S.P. DNA-dependent protein kinase interacts with antigen receptor response element binding proteins NF90 and NF45. J. Biol. Chem. 273 (1998) 2136-2145
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 2136-2145
-
-
Ting, N.S.1
Kao, P.N.2
Chan, D.W.3
Lintott, L.G.4
Lees-Miller, S.P.5
-
27
-
-
34247477667
-
Autophosphorylation of DNA-PKCS regulates its dynamics at DNA double-strand breaks
-
Uematsu N., Weterings E., Yano K., Morotomi-Yano K., Jakob B., Taucher-Scholz G., Mari P.O., van Gent D.C., Chen B.P., and Chen D.J. Autophosphorylation of DNA-PKCS regulates its dynamics at DNA double-strand breaks. J. Cell. Biol. 177 (2007) 219-229
-
(2007)
J. Cell. Biol.
, vol.177
, pp. 219-229
-
-
Uematsu, N.1
Weterings, E.2
Yano, K.3
Morotomi-Yano, K.4
Jakob, B.5
Taucher-Scholz, G.6
Mari, P.O.7
van Gent, D.C.8
Chen, B.P.9
Chen, D.J.10
-
28
-
-
10044225999
-
Autophosphorylation of ataxia-telangiectasia mutated is regulated by protein phosphatase 2A
-
Goodarzi A.A., Jonnalagadda J.C., Douglas P., Young D., Ye R., Moorhead G.B., Lees-Miller S.P., and Khanna K.K. Autophosphorylation of ataxia-telangiectasia mutated is regulated by protein phosphatase 2A. EMBO J. 23 (2004) 4451-4461
-
(2004)
EMBO J.
, vol.23
, pp. 4451-4461
-
-
Goodarzi, A.A.1
Jonnalagadda, J.C.2
Douglas, P.3
Young, D.4
Ye, R.5
Moorhead, G.B.6
Lees-Miller, S.P.7
Khanna, K.K.8
-
29
-
-
2242484657
-
Identification of in vitro and in vivo phosphorylation sites in the catalytic subunit of the DNA-dependent protein kinase
-
Douglas P., Sapkota G.P., Morrice N., Yu Y., Goodarzi A.A., Merkle D., Meek K., Alessi D.R., and Lees-Miller S.P. Identification of in vitro and in vivo phosphorylation sites in the catalytic subunit of the DNA-dependent protein kinase. Biochem. J. 368 (2002) 243-251
-
(2002)
Biochem. J.
, vol.368
, pp. 243-251
-
-
Douglas, P.1
Sapkota, G.P.2
Morrice, N.3
Yu, Y.4
Goodarzi, A.A.5
Merkle, D.6
Meek, K.7
Alessi, D.R.8
Lees-Miller, S.P.9
-
30
-
-
0032972734
-
DNA-dependent protein kinase phosphorylation sites in Ku 70/80 heterodimer
-
Chan D.W., Ye R., Veillette C.J., and Lees-Miller S.P. DNA-dependent protein kinase phosphorylation sites in Ku 70/80 heterodimer. Biochemistry 38 (1999) 1819-1828
-
(1999)
Biochemistry
, vol.38
, pp. 1819-1828
-
-
Chan, D.W.1
Ye, R.2
Veillette, C.J.3
Lees-Miller, S.P.4
-
31
-
-
9744271049
-
Identification and characterization of a novel and specific inhibitor of the ataxia-telangiectasia mutated kinase ATM
-
Hickson I., Zhao Y., Richardson C.J., Green S.J., Martin N.M., Orr A.I., Reaper P.M., Jackson S.P., Curtin N.J., and Smith G.C. Identification and characterization of a novel and specific inhibitor of the ataxia-telangiectasia mutated kinase ATM. Cancer Res. 64 (2004) 9152-9159
-
(2004)
Cancer Res.
, vol.64
, pp. 9152-9159
-
-
Hickson, I.1
Zhao, Y.2
Richardson, C.J.3
Green, S.J.4
Martin, N.M.5
Orr, A.I.6
Reaper, P.M.7
Jackson, S.P.8
Curtin, N.J.9
Smith, G.C.10
-
32
-
-
38049034405
-
Crystal structure of human XLF/Cernunnos reveals unexpected differences from XRCC4 with implications for NHEJ
-
Li Y., Chirgadze D.Y., Bolanos-Garcia V.M., Sibanda B.L., Davies O.R., Ahnesorg P., Jackson S.P., and Blundell T.L. Crystal structure of human XLF/Cernunnos reveals unexpected differences from XRCC4 with implications for NHEJ. EMBO J. 27 (2008) 290-300
-
(2008)
EMBO J.
, vol.27
, pp. 290-300
-
-
Li, Y.1
Chirgadze, D.Y.2
Bolanos-Garcia, V.M.3
Sibanda, B.L.4
Davies, O.R.5
Ahnesorg, P.6
Jackson, S.P.7
Blundell, T.L.8
-
33
-
-
0347627530
-
The 3D solution structure of the C-terminal region of Ku86 (Ku86CTR)
-
Harris R., Esposito D., Sankar A., Maman J.D., Hinks J.A., Pearl L.H., and Driscoll P.C. The 3D solution structure of the C-terminal region of Ku86 (Ku86CTR). J. Mol. Biol. 335 (2004) 573-582
-
(2004)
J. Mol. Biol.
, vol.335
, pp. 573-582
-
-
Harris, R.1
Esposito, D.2
Sankar, A.3
Maman, J.D.4
Hinks, J.A.5
Pearl, L.H.6
Driscoll, P.C.7
-
34
-
-
0035851127
-
The three-dimensional structure of the C-terminal DNA-binding domain of human Ku70
-
Zhang Z., Zhu L., Lin D., Chen F., Chen D.J., and Chen Y. The three-dimensional structure of the C-terminal DNA-binding domain of human Ku70. J. Biol. Chem. 276 (2001) 38231-38236
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 38231-38236
-
-
Zhang, Z.1
Zhu, L.2
Lin, D.3
Chen, F.4
Chen, D.J.5
Chen, Y.6
-
35
-
-
1542581549
-
Solution structure of the C-terminal domain of Ku80 suggests important sites for protein-protein interactions
-
Zhang Z., Hu W., Cano L., Lee T.D., Chen D.J., and Chen Y. Solution structure of the C-terminal domain of Ku80 suggests important sites for protein-protein interactions. Structure (Camb.) 12 (2004) 495-502
-
(2004)
Structure (Camb.)
, vol.12
, pp. 495-502
-
-
Zhang, Z.1
Hu, W.2
Cano, L.3
Lee, T.D.4
Chen, D.J.5
Chen, Y.6
-
36
-
-
35948988110
-
A critical role for the C-terminus of Nej1 protein in Lif1p association, DNA binding and non-homologous end-joining
-
Sulek M., Yarrington R., McGibbon G., Boeke J.D., and Junop M. A critical role for the C-terminus of Nej1 protein in Lif1p association, DNA binding and non-homologous end-joining. DNA Repair (Amst.) 6 (2007) 1805-1818
-
(2007)
DNA Repair (Amst.)
, vol.6
, pp. 1805-1818
-
-
Sulek, M.1
Yarrington, R.2
McGibbon, G.3
Boeke, J.D.4
Junop, M.5
-
37
-
-
33646106590
-
gammaH2AX and MDC1: Anchoring the DNA-damage-response machinery to broken chromosomes
-
Stucki M., and Jackson S.P. gammaH2AX and MDC1: Anchoring the DNA-damage-response machinery to broken chromosomes. DNA Repair (Amst.) 5 (2006) 534-543
-
(2006)
DNA Repair (Amst.)
, vol.5
, pp. 534-543
-
-
Stucki, M.1
Jackson, S.P.2
|