The amyloid precursor protein: A biochemical enigma in brain development, function and disease

FEBS Letters

Volumn 587, Issue 13, 2013, Pages 2046-2054

  Nalivaeva, Natalia N ^a,b   Turner, Anthony J ^a  

^a UNIVERSITY OF LEEDS   (United Kingdom)

^b SECHENOV INSTITUTE OF EVOLUTIONARY PHYSIOLOGY AND BIOCHEMISTRY   (Russian Federation)

Author keywords

Amyloid precursor protein APP intracellular domain (AICD) Histone deacetylase Hypoxia Mediator Neprilysin

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; BACE 1 PROTEIN; BETA SECRETASE; ISOPROTEIN; MEMBRANE METALLOENDOPEPTIDASE; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; BRAIN DEVELOPMENT; BRAIN DISEASE; BRAIN HYPOXIA; BRAIN ISCHEMIA; CARBOXY TERMINAL SEQUENCE; ENVIRONMENTAL FACTOR; EPIGENETICS; GENE EXPRESSION REGULATION; GENE REGULATORY NETWORK; HUMAN; MEMORY; NERVE CELL; NERVE CELL PLASTICITY; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN CLEAVAGE; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN METABOLISM; PROTEIN PROCESSING; PROTEIN SECRETION; REVIEW; STRESS; TRANSCRIPTION REGULATION;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; BRAIN; BRAIN ISCHEMIA; CELL HYPOXIA; GENE EXPRESSION REGULATION; HUMANS; PROTEIN ISOFORMS; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEOLYSIS;

EID: 84878946078     PISSN: 00145793     EISSN: 18733468     Source Type: Journal    
DOI: 10.1016/j.febslet.2013.05.010     Document Type: Review

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