-
1
-
-
0242300624
-
Games played by rogue proteins in prion disorders and Alzheimer's disease
-
Aguzzi A, Haass C (2003) Games played by rogue proteins in prion disorders and Alzheimer's disease. Science 302: 814-818
-
(2003)
Science
, vol.302
, pp. 814-818
-
-
Aguzzi, A.1
Haass, C.2
-
2
-
-
0036441486
-
A cell biological perspective on Alzheimer's disease
-
Annaert W, De Strooper B (2002) A cell biological perspective on Alzheimer's disease. Annu Rev Cell Dev Biol 18: 25-51
-
(2002)
Annu Rev Cell Dev Biol
, vol.18
, pp. 25-51
-
-
Annaert, W.1
De Strooper, B.2
-
3
-
-
0033026550
-
Proteolytic fragments of Alzheimer's disease-associated presenilin 1 are present in synaptic organelles and growth cone membranes of rat brain
-
Beher D, Elle C, Underwood J, Davis JB, Ward R, Karran E, Masters CL, Beyreuther K, Multhaup G (1999) Proteolytic fragments of Alzheimer's disease-associated presenilin 1 are present in synaptic organelles and growth cone membranes of rat brain. J Neurochem 72: 1564-1573
-
(1999)
J Neurochem
, vol.72
, pp. 1564-1573
-
-
Beher, D.1
Elle, C.2
Underwood, J.3
Davis, J.B.4
Ward, R.5
Karran, E.6
Masters, C.L.7
Beyreuther, K.8
Multhaup, G.9
-
4
-
-
0030030005
-
Regulation of amyloid protein precursor (APP) binding to collagen and mapping of the binding sites on APP and collagen type I
-
Beher D, Hesse L, Masters CL, Multhaup G (1996) Regulation of amyloid protein precursor (APP) binding to collagen and mapping of the binding sites on APP and collagen type I. J Biol Chem 271: 1613-1620
-
(1996)
J Biol Chem
, vol.271
, pp. 1613-1620
-
-
Beher, D.1
Hesse, L.2
Masters, C.L.3
Multhaup, G.4
-
5
-
-
0033972608
-
What the evolution of the amyloid protein precursor supergene family tells us about its function
-
Coulson EJ, Paliga K, Beyreuther K, Masters CL (2000) What the evolution of the amyloid protein precursor supergene family tells us about its function. Neurochem Int 36: 175-184
-
(2000)
Neurochem Int
, vol.36
, pp. 175-184
-
-
Coulson, E.J.1
Paliga, K.2
Beyreuther, K.3
Masters, C.L.4
-
6
-
-
2442592973
-
The proteolytic processing of the amyloid precursor protein gene family members APLP-1 and APLP-2 involves alpha-, beta-, gamma-, and epsilon-like cleavages: Modulation of APLP-1 processing by n-glycosylation
-
Eggert S, Paliga K, Soba P, Evin G, Masters CL, Weidemann A, Beyreuther K (2004) The proteolytic processing of the amyloid precursor protein gene family members APLP-1 and APLP-2 involves alpha-, beta-, gamma-, and epsilon-like cleavages: modulation of APLP-1 processing by n-glycosylation. J Biol Chem 279: 18146-18156
-
(2004)
J Biol Chem
, vol.279
, pp. 18146-18156
-
-
Eggert, S.1
Paliga, K.2
Soba, P.3
Evin, G.4
Masters, C.L.5
Weidemann, A.6
Beyreuther, K.7
-
7
-
-
0027215550
-
Intraneuronal compartments of the amyloid precursor protein
-
Ferreira A, Caceres A, Kosik KS (1993) Intraneuronal compartments of the amyloid precursor protein. J Neurosci 13: 3112-3123
-
(1993)
J Neurosci
, vol.13
, pp. 3112-3123
-
-
Ferreira, A.1
Caceres, A.2
Kosik, K.S.3
-
8
-
-
0034329291
-
Mice with combined gene knock-outs reveal essential and partially redundant functions of amyloid precursor protein family members
-
Heber S, Herms J, Gajic V, Hainfellner J, Aguzzi A, Rulicke T, von Kretzschmar H, von Koch C, Sisodia S, Tremml P, Lipp HP, Wolfer DP, Muller U (2000) Mice with combined gene knock-outs reveal essential and partially redundant functions of amyloid precursor protein family members. J Neurosci 20: 7951-7963
-
(2000)
J Neurosci
, vol.20
, pp. 7951-7963
-
-
Heber, S.1
Herms, J.2
Gajic, V.3
Hainfellner, J.4
Aguzzi, A.5
Rulicke, T.6
Von Kretzschmar, H.7
Von Koch, C.8
Sisodia, S.9
Tremml, P.10
Lipp, H.P.11
Wolfer, D.P.12
Muller, U.13
-
9
-
-
8144230876
-
Cortical dysplasia resembling human type 2 lissencephaly in mice lacking all three APP family members
-
Herms J, Anliker B, Heber S, Ring S, Fuhrmann M, Kretzschmar H, Sisodia S, Muller U (2004) Cortical dysplasia resembling human type 2 lissencephaly in mice lacking all three APP family members. EMBO J 23: 4106-4115
-
(2004)
EMBO J
, vol.23
, pp. 4106-4115
-
-
Herms, J.1
Anliker, B.2
Heber, S.3
Ring, S.4
Fuhrmann, M.5
Kretzschmar, H.6
Sisodia, S.7
Muller, U.8
-
10
-
-
1642505399
-
Activation of EGF Receptor Kinase by L1-mediated Homophilic Cell Interactions
-
Islam R, Kristiansen LV, Romani S, Garcia-Alonso L, Hortsch M (2004) Activation of EGF Receptor Kinase by L1-mediated Homophilic Cell Interactions. Mol Biol Cell 15: 2003-2012
-
(2004)
Mol Biol Cell
, vol.15
, pp. 2003-2012
-
-
Islam, R.1
Kristiansen, L.V.2
Romani, S.3
Garcia-Alonso, L.4
Hortsch, M.5
-
11
-
-
0029015855
-
Selective localization of amyloid precursor-like protein 1 in the cerebral cortex postsynaptic density
-
Kim TW, Wu K, Xu JL, McAuliffe G, Tanzi RE, Wasco W, Black IB (1995) Selective localization of amyloid precursor-like protein 1 in the cerebral cortex postsynaptic density. Brain Res Mol Brain Res 32: 36-44
-
(1995)
Brain Res Mol Brain Res
, vol.32
, pp. 36-44
-
-
Kim, T.W.1
Wu, K.2
Xu, J.L.3
McAuliffe, G.4
Tanzi, R.E.5
Wasco, W.6
Black, I.B.7
-
12
-
-
0036743877
-
Creation of a GAL4/UAS-coupled inducible gene expression system for use in Drosophila cultured cell lines
-
Klueg KM, Alvarado D, Muskavitch MA, Duffy JB (2002) Creation of a GAL4/UAS-coupled inducible gene expression system for use in Drosophila cultured cell lines. Genesis 34: 119-122
-
(2002)
Genesis
, vol.34
, pp. 119-122
-
-
Klueg, K.M.1
Alvarado, D.2
Muskavitch, M.A.3
Duffy, J.B.4
-
13
-
-
0032705926
-
Ligand-receptor interactions and trans-endocytosis of Delta, Serrate and Notch: Members of the Notch signalling pathway in Drosophila
-
Klueg KM, Muskavitch MA (1999) Ligand-receptor interactions and trans-endocytosis of Delta, Serrate and Notch: members of the Notch signalling pathway in Drosophila. J Cell Sci 112 (Part 19): 3289-3297
-
(1999)
J Cell Sci
, vol.112
, Issue.19 PART
, pp. 3289-3297
-
-
Klueg, K.M.1
Muskavitch, M.A.2
-
14
-
-
0029954239
-
Generation of mice with a 200-kb amyloid precursor protein gene deletion by Cre recombinase-mediated site-specific recombination in embryonic stem cells
-
Li ZW, Stark G, Gotz J, Rulicke T, Gschwind M, Huber G, Muller U, Weissmann C (1996) Generation of mice with a 200-kb amyloid precursor protein gene deletion by Cre recombinase-mediated site-specific recombination in embryonic stem cells. Proc Natl Acad Sci USA 93: 6158-6162
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 6158-6162
-
-
Li, Z.W.1
Stark, G.2
Gotz, J.3
Rulicke, T.4
Gschwind, M.5
Huber, G.6
Muller, U.7
Weissmann, C.8
-
15
-
-
2442543552
-
Cell-type-specific processing of the amyloid precursor protein by Presenilin during Drosophila development
-
Loewer A, Soba P, Beyreuther K, Paro R, Merdes G (2004) Cell-type-specific processing of the amyloid precursor protein by Presenilin during Drosophila development. EMBO Rep 5: 405-411
-
(2004)
EMBO Rep
, vol.5
, pp. 405-411
-
-
Loewer, A.1
Soba, P.2
Beyreuther, K.3
Paro, R.4
Merdes, G.5
-
16
-
-
0028914672
-
Expression in mouse embryos and in adult mouse brain of three members of the amyloid precursor protein family, of the alpha-2-macroglobulin receptor/low density lipoprotein receptor-related protein and of its ligands apolipoprotein E, lipoprotein lipase, alpha-2-macroglobulin and the 40,000 molecular weight receptor-associated protein
-
Lorent K, Overbergh L, Moechars D, De Strooper B, Van Leuven F, Van den Berghe H (1995) Expression in mouse embryos and in adult mouse brain of three members of the amyloid precursor protein family, of the alpha-2-macroglobulin receptor/low density lipoprotein receptor-related protein and of its ligands apolipoprotein E, lipoprotein lipase, alpha-2-macroglobulin and the 40,000 molecular weight receptor-associated protein. Neuroscience 65: 1009-1025
-
(1995)
Neuroscience
, vol.65
, pp. 1009-1025
-
-
Lorent, K.1
Overbergh, L.2
Moechars, D.3
De Strooper, B.4
Van Leuven, F.5
Van Den Berghe, H.6
-
17
-
-
0032079899
-
Post-translational processing and turnover kinetics of presynaptically targeted amyloid precursor superfamily proteins in the central nervous system
-
Lyckman AW, Confaloni AM, Thinakaran G, Sisodia SS, Moya KL (1998) Post-translational processing and turnover kinetics of presynaptically targeted amyloid precursor superfamily proteins in the central nervous system. J Biol Chem 273: 11100-11106
-
(1998)
J Biol Chem
, vol.273
, pp. 11100-11106
-
-
Lyckman, A.W.1
Confaloni, A.M.2
Thinakaran, G.3
Sisodia, S.S.4
Moya, K.L.5
-
18
-
-
8144229817
-
Interference of human and Drosophila APP and APP-like proteins with PNS development in Drosophila
-
Merdes G, Soba P, Loewer A, Bilic MV, Beyreuther K, Paro R (2004) Interference of human and Drosophila APP and APP-like proteins with PNS development in Drosophila. EMBO J 23: 4082-4095
-
(2004)
EMBO J
, vol.23
, pp. 4082-4095
-
-
Merdes, G.1
Soba, P.2
Loewer, A.3
Bilic, M.V.4
Beyreuther, K.5
Paro, R.6
-
19
-
-
0026669747
-
Functional expression of a full-length cDNA coding for rat neural cell adhesion molecule L1 mediates homophilic intercellular adhesion and migration of cerebellar neurons
-
Miura M, Asou H, Kobayashi M, Uyemura K (1992) Functional expression of a full-length cDNA coding for rat neural cell adhesion molecule L1 mediates homophilic intercellular adhesion and migration of cerebellar neurons. J Biol Chem 267: 10752-10758
-
(1992)
J Biol Chem
, vol.267
, pp. 10752-10758
-
-
Miura, M.1
Asou, H.2
Kobayashi, M.3
Uyemura, K.4
-
20
-
-
0028329090
-
The amyloid precursor protein is developmentally regulated and correlated with synaptogenesis
-
Moya KL, Benowitz LI, Schneider GE, Allinquant B (1994) The amyloid precursor protein is developmentally regulated and correlated with synaptogenesis. Dev Biol 161: 597-603
-
(1994)
Dev Biol
, vol.161
, pp. 597-603
-
-
Moya, K.L.1
Benowitz, L.I.2
Schneider, G.E.3
Allinquant, B.4
-
21
-
-
0031437769
-
Human amyloid precursor-like protein 1 - cDNA cloning, ectopic expression in COS-7 cells and identification of soluble forms in the cerebrospinal fluid
-
Paliga K, Peraus G, Kreger S, Durrwang U, Hesse L, Multhaup G, Masters CL, Beyreuther K, Weidemann A (1997) Human amyloid precursor-like protein 1 - cDNA cloning, ectopic expression in COS-7 cells and identification of soluble forms in the cerebrospinal fluid. Eur J Biochem 250: 354-363
-
(1997)
Eur J Biochem
, vol.250
, pp. 354-363
-
-
Paliga, K.1
Peraus, G.2
Kreger, S.3
Durrwang, U.4
Hesse, L.5
Multhaup, G.6
Masters, C.L.7
Beyreuther, K.8
Weidemann, A.9
-
22
-
-
0028535647
-
APP gene family: Unique age-associated changes in splicing of Alzheimer's betaA4-amyloid protein precursor
-
Sandbrink R, Masters CL, Beyreuther K (1994) APP gene family: unique age-associated changes in splicing of Alzheimer's betaA4-amyloid protein precursor. Neurobiol Dis 1: 13-24
-
(1994)
Neurobiol Dis
, vol.1
, pp. 13-24
-
-
Sandbrink, R.1
Masters, C.L.2
Beyreuther, K.3
-
23
-
-
1842329227
-
Expression of the APP gene family in brain cells, brain development and aging
-
Sandbrink R, Monning U, Masters CL, Beyreuther K (1997) Expression of the APP gene family in brain cells, brain development and aging. Gerontology 43: 119-131
-
(1997)
Gerontology
, vol.43
, pp. 119-131
-
-
Sandbrink, R.1
Monning, U.2
Masters, C.L.3
Beyreuther, K.4
-
24
-
-
0035823495
-
Homodimerization of amyloid precursor protein and its implication in the amyloidogenic pathway of Alzheimer's disease
-
Scheuermann S, Hambsch B, Hesse L, Stumm J, Schmidt C, Beher D, Bayer TA, Beyreuther K, Multhaup G (2001) Homodimerization of amyloid precursor protein and its implication in the amyloidogenic pathway of Alzheimer's disease. J Biol Chem 276: 33923-33929
-
(2001)
J Biol Chem
, vol.276
, pp. 33923-33929
-
-
Scheuermann, S.1
Hambsch, B.2
Hesse, L.3
Stumm, J.4
Schmidt, C.5
Beher, D.6
Bayer, T.A.7
Beyreuther, K.8
Multhaup, G.9
-
25
-
-
0037145061
-
Ligand-induced, receptor-mediated dimerization and activation of EGF receptor
-
Schlessinger J (2002) Ligand-induced, receptor-mediated dimerization and activation of EGF receptor. Cell 110: 669-672
-
(2002)
Cell
, vol.110
, pp. 669-672
-
-
Schlessinger, J.1
-
26
-
-
0028059841
-
Expression of a ubiquitous, cross-reactive homologue of the mouse beta-amyloid precursor protein (APP)
-
Slunt HH, Thinakaran G, Von Koch C, Lo AC, Tanzi RE, Sisodia SS (1994) Expression of a ubiquitous, cross-reactive homologue of the mouse beta-amyloid precursor protein (APP). J Biol Chem 269: 2637-2644
-
(1994)
J Biol Chem
, vol.269
, pp. 2637-2644
-
-
Slunt, H.H.1
Thinakaran, G.2
Von Koch, C.3
Lo, A.C.4
Tanzi, R.E.5
Sisodia, S.S.6
-
27
-
-
0026523924
-
Association and release of the amyloid protein precursor of Alzheimer's disease from chick brain extracellular matrix
-
Small DH, Nurcombe V, Moir R, Michaelson S, Monard D, Beyreuther K, Masters CL (1992) Association and release of the amyloid protein precursor of Alzheimer's disease from chick brain extracellular matrix. J Neurosci 12: 4143-4150
-
(1992)
J Neurosci
, vol.12
, pp. 4143-4150
-
-
Small, D.H.1
Nurcombe, V.2
Moir, R.3
Michaelson, S.4
Monard, D.5
Beyreuther, K.6
Masters, C.L.7
-
28
-
-
0242656305
-
The roles of cadherins and nectins in interneuronal synapse formation
-
Takai Y, Shimizu K, Ohtsuka T (2003) The roles of cadherins and nectins in interneuronal synapse formation. Curr Opin Neurobiol 13: 520-526
-
(2003)
Curr Opin Neurobiol
, vol.13
, pp. 520-526
-
-
Takai, Y.1
Shimizu, K.2
Ohtsuka, T.3
-
29
-
-
0023850791
-
Protease inhibitor domain encoded by an amyloid protein precursor mRNA associated with Alzheimer's disease
-
Tanzi RE, McClatchey AI, Lamperti ED, Villa-Komaroff L, Gusella JF, Neve RL (1988) Protease inhibitor domain encoded by an amyloid protein precursor mRNA associated with Alzheimer's disease. Nature 331: 528-530
-
(1988)
Nature
, vol.331
, pp. 528-530
-
-
Tanzi, R.E.1
McClatchey, A.I.2
Lamperti, E.D.3
Villa-Komaroff, L.4
Gusella, J.F.5
Neve, R.L.6
-
30
-
-
0031470093
-
Generation of APLP2 KO mice and early postnatal lethality in APLP2/APP double KO mice
-
von Koch CS, Zheng H, Chen H, Trumbauer M, Thinakaran G, van der Ploeg LH, Price DL, Sisodia SS (1997) Generation of APLP2 KO mice and early postnatal lethality in APLP2/APP double KO mice. Neurobiol Aging 18: 661-669
-
(1997)
Neurobiol Aging
, vol.18
, pp. 661-669
-
-
Von Koch, C.S.1
Zheng, H.2
Chen, H.3
Trumbauer, M.4
Thinakaran, G.5
Van Der Ploeg, L.H.6
Price, D.L.7
Sisodia, S.S.8
-
31
-
-
10944258798
-
Ectodomain shedding and intramembrane cleavage of mammalian Notch proteins is not regulated through oligomerization
-
Vooijs M, Schroeter EH, Pan Y, Blandford M, Kopan R (2004) Ectodomain shedding and intramembrane cleavage of mammalian Notch proteins is not regulated through oligomerization. J Biol Chem 279: 50864-50873
-
(2004)
J Biol Chem
, vol.279
, pp. 50864-50873
-
-
Vooijs, M.1
Schroeter, E.H.2
Pan, Y.3
Blandford, M.4
Kopan, R.5
-
32
-
-
13944274830
-
Defective neuromuscular synapses in mice lacking amyloid precursor protein (APP) and APP-Like protein 2
-
Wang P, Yang G, Mosier DR, Chang P, Zaidi T, Gong YD, Zhao NM, Dominguez B, Lee KF, Gan WB, Zheng H (2005) Defective neuromuscular synapses in mice lacking amyloid precursor protein (APP) and APP-Like protein 2. J Neurosci 25: 1219-1225
-
(2005)
J Neurosci
, vol.25
, pp. 1219-1225
-
-
Wang, P.1
Yang, G.2
Mosier, D.R.3
Chang, P.4
Zaidi, T.5
Gong, Y.D.6
Zhao, N.M.7
Dominguez, B.8
Lee, K.F.9
Gan, W.B.10
Zheng, H.11
-
33
-
-
4143105782
-
The X-ray structure of an antiparallel dimer of the human amyloid precursor protein E2 domain
-
Wang Y, Ha Y (2004) The X-ray structure of an antiparallel dimer of the human amyloid precursor protein E2 domain. Mol Cell 15: 343-353
-
(2004)
Mol Cell
, vol.15
, pp. 343-353
-
-
Wang, Y.1
Ha, Y.2
-
34
-
-
0024550204
-
Identification, biogenesis, and localization of precursors of Alzheimer's disease A4 amyloid protein
-
Weidemann A, Konig G, Bunke D, Fischer P, Salbaum JM, Masters CL, Beyreuther K (1989) Identification, biogenesis, and localization of precursors of Alzheimer's disease A4 amyloid protein. Cell 57: 115-126
-
(1989)
Cell
, vol.57
, pp. 115-126
-
-
Weidemann, A.1
Konig, G.2
Bunke, D.3
Fischer, P.4
Salbaum, J.M.5
Masters, C.L.6
Beyreuther, K.7
-
35
-
-
0031020284
-
Cell surface amyloid beta-protein precursor colocalizes with beta 1 integrins at substrate contact sites in neural cells
-
Yamazaki T, Koo EH, Selkoe DJ (1997) Cell surface amyloid beta-protein precursor colocalizes with beta 1 integrins at substrate contact sites in neural cells. J Neurosci 17: 1004-1010
-
(1997)
J Neurosci
, vol.17
, pp. 1004-1010
-
-
Yamazaki, T.1
Koo, E.H.2
Selkoe, D.J.3
-
36
-
-
0028913471
-
Trafficking of cell surface beta-amyloid precursor protein: Retrograde and transcytotic transport in cultured neurons
-
Yamazaki T, Selkoe DJ, Koo EH (1995) Trafficking of cell surface beta-amyloid precursor protein: retrograde and transcytotic transport in cultured neurons. J Cell Biol 129: 431-442
-
(1995)
J Cell Biol
, vol.129
, pp. 431-442
-
-
Yamazaki, T.1
Selkoe, D.J.2
Koo, E.H.3
-
37
-
-
0028988801
-
Amyloid precursor protein-deficient mice show reactive gliosis and decreased locomotor activity
-
Zheng H, Jiang M, Trumbauer ME, Sirinathsinghji DJ, Hopkins R, Smith DW, Heavens RP, Dawson GR, Boyce S, Conner MW, Stevens KA, Slunt HH, Sisoda SS, Chen HY, Van der Ploeg LH (1995) beta-Amyloid precursor protein-deficient mice show reactive gliosis and decreased locomotor activity. Cell 81: 525-531
-
(1995)
Cell
, vol.81
, pp. 525-531
-
-
Zheng, H.1
Jiang, M.2
Trumbauer, M.E.3
Sirinathsinghji, D.J.4
Hopkins, R.5
Smith, D.W.6
Heavens, R.P.7
Dawson, G.R.8
Boyce, S.9
Conner, M.W.10
Stevens, K.A.11
Slunt, H.H.12
Sisoda, S.S.13
Chen, H.Y.14
Van Der Ploeg, L.H.15
|