Characterization of amyloid-β precursor protein intracellular domain-associated transcriptional complexes in SH-SY5Y neurocytes

Neuroscience Bulletin

Volumn 28, Issue 3, 2012, Pages 259-270

  Yang, Wulin ^a   Lau, Amy Yong Chen ^b   Luo, Shuizhong ^a   Zhu, Qian ^c   Lu, Li ^c  

^a HEFEI UNIVERSITY OF TECHNOLOGY   (China)

^b AGENCY FOR SCIENCE   (Singapore)

^c SHANXI MEDICAL UNIVERSITY   (China)

Author keywords

AICD; Alzheimer's disease; Amyloid precursor protein; Apoptosis; Biotinylation

Indexed keywords

AMYLOID BETA PROTEIN; BIOTIN; BIOTIN LIGASE; LIGASE; STREPTAVIDIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR CUX1; TRANSCRIPTION FACTOR SPT5; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; APOPTOSIS; ARTICLE; BIOTINYLATION; CELL DIFFERENTIATION; CELL LINE; CELL PROLIFERATION; CONTROLLED STUDY; ESCHERICHIA COLI; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; MASS SPECTROMETRY; NERVE CELL; NERVE CELL NECROSIS; PATHOGENESIS; PATHOPHYSIOLOGY; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN PURIFICATION; TRANSCRIPTION INITIATION;

AMYLOID BETA-PROTEIN PRECURSOR; APOPTOSIS; CELL LINE, TUMOR; CELL PROLIFERATION; HUMANS; NEURONS; PROTEIN STRUCTURE, TERTIARY; TRANSCRIPTION, GENETIC;

EID: 84864692316     PISSN: 16737067     EISSN: 19958218     Source Type: Journal    
DOI: 10.1007/s12264-012-1243-5     Document Type: Article

References (21)

1. Sisodia SS, St George-Hyslop PH. γ-Secretase, notch, Aβ and Alzheimer's disease: Where do the presenilins fit in? Nat Rev Neurosci 2002, 3:281-290.
2. Ghosal K, Vogt DL, Liang M, Shen Y, Lamb BT, Pimplikar SW. Alzheimer's disease-like pathological features in transgenic mice expressing the APP intracellular domain. Proc Natl Acad Sci U S A 2009, 106:18367-18372.
3. von Rotz RC, Kohli BM, Bosset J, Meier M, Suzuki T, Nitsch RM, et al. The APP intracellular domain forms nuclear multiprotein complexes and regulates the transcription of its own precursor. J Cell Sci 2004, 117:4435-4448.
4. Hardy J, Selkoe DJ. The amyloid hypothesis of Alzheimer's disease: Progress and problems on the road to therapeutics. Science 2002, 297:353-356.
5. Thinakaran G, Koo EH. Amyloid precursor protein trafficking, processing and function. J Biol Chem 2008, 283:29615-29619.
6. Cao X, Südhof TC. A transcriptionally active complex of APP with Fe65 and histone acetyltransferase Tip60. Science 2001, 293:115-120.
7. Muller T, Meyer HE, Egensperger R, Marcus K. The amyloid precursor protein intracellular domain (AICD) as modulator of gene expression, apoptosis, and cytoskeletal dynamics - relevance for Alzheimer's disease. Prog Neurobiol 2008, 85:393-406.
8. Pimplikar SW. Reassessing the amyloid cascade hypothesis of Alzheimer's disease. Int J Biochem Cell Biol 2009, 41:1261-1268.
9. Saganich MJ, Schroeder BE, Galvan V, Bredesen DE, Koo EH, Heinemann SF. Deficits in synaptic transmission and learning in amyloid precursor protein (APP) transgenic mice require C-terminal cleavage of APP. J Neurosci 2006, 26:13428-13436.
10. Slomnicki LP, Lesniak W. A putative role of the amyloid precursor protein intracellular domain (AICD) in transcription. Acta Neurobiol Exp (Wars) 2008, 68:219-228.
11. Kim HS, Kim EM, Lee JP, Park CH, Kim S, Seo Jh, et al. CTerminal fragments of amyloid precursor protein exert neurotoxicity by inducing glycogen synthase kinase-3beta expression. FASEB J 2003, 17:1951-1953.
12. Swistowski A, Zhang Q, Orcholski ME, Crippen D, Vitelli C, Kurakin A, et al. Novel mediators of amyloid precursor protein signaling. J Neurosci 2009, 29:15703-15712.
13. Boer Ed, Rodriguez P, Bonte E, Krijgsveld J, Katsantoni E, Heck A, et al. Efficient biotinylation and single-step purification of tagged transcriptional factors in mammalian cells and transgenic mice. Proc Natl Acad Sci U S A 2003, 100:7480-7485.
14. Paul BM, Vassmer D, Taylor A, Magenheimer L, Carlton CG, Piontek KB, et al. Ectopic expression of Cux1 is associated with reduced p27 expression and increased apoptosis during late stage cyst progression upon inactivation of Pkd1 in collecting ducts. Dev Dyn 2011, 240:1493-1501.
15. Madeira A, Pommet JM, Prochiantz A, Allinquant B. SET protein (TAF1beta, I2PP2A) is involved in neuronal apoptosis induced by an amyloid precursor protein cytoplasmic subdomain. FASEB J 2005, 19:1905-1907.
16. Xu X, Zhou H, Boyer TG. Mediator is a transducer of amyloidprecursorprotein-dependent nuclear signalling. EMBO Rep 2011, 12:216-222.
17. Roncarati R, Sestan N, Scheinfeld MH, Berechid BE, Lopez PA, Meucci O, et al. The gamma-secretase-generated intracellular domain of beta-amyloid precursor protein binds Numb and inhibits Notch signaling. Proc Natl Acad Sci U S A 2002, 99:7102-7107.
18. Muller T, Concannon CG, Ward MW, Walsh CM, Tirniceriu AL, Tribl F, et al. Modulation of gene expression and cytoskeletal dynamics by the amyloid precursor protein intracellular domain (AICD). Mol Biol Cell 2007, 18:201-210.
19. Michl P, Knobel B, Downward J. CUTL1 is phosphorylated by protein kinase A, modulating its effects on cell proliferation and motility. J Biol Chem 2006, 281:15138-15144.
20. Liu Z, Zhou Z, Chen G, Bao S. A putative transcriptional elongation factor hIws1 is essential for mammalian cell proliferation. Biochem Biophys Res Commun 2007, 353:47-53.
21. Zhang Z, Hartmann H, Do VM, Abramowski D, Sturchler-Pierrat C, Staufenbiel M, et al. Destabilization of ß-catenin by mutations in presenilin-1 potentiates neuronal apoptosis. Nature 1998, 395:698-702.