Development of transgenic rats producing human β-amyloid precursor protein as a model for Alzheimer's disease: Transgene and endogenous APP genes are regulated tissue-specifically

BMC Neuroscience

Volumn 9, Issue , 2008, Pages 28-

  Agca, Cansu ^a   Fritz, Jason J ^b   Walker, Lary C ^b,c   Levey, Allan I ^b   Chan, Anthony W S ^c   Lah, James J ^b   Agca, Yuksel ^a  

^a UNIVERSITY OF MISSOURI   (United States)

^b EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c EMORY UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN[1-40]; AMYLOID BETA PROTEIN[1-42]; AMYLOID PRECURSOR PROTEIN; COMPLEMENTARY DNA; ENHANCED GREEN FLUORESCENT PROTEIN; LENTIVIRUS VECTOR; MESSENGER RNA; UBIQUITIN C;

ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN NERVE CELL; BRAIN TISSUE; CONTROLLED STUDY; DNA SEQUENCE; GENE EXPRESSION; GENE EXPRESSION REGULATION; GLIA CELL; HEART; HEMIZYGOSITY; HOMOZYGOSITY; IMMUNOHISTOCHEMISTRY; INBRED STRAIN; KIDNEY PARENCHYMA; LIVER PARENCHYMA; LUNG PARENCHYMA; MOUSE; NONHUMAN; NORTHERN BLOTTING; PROMOTER REGION; PROTEIN BLOOD LEVEL; RAT; TISSUE SPECIFICITY; TRANSGENIC RAT; VIRAL GENE DELIVERY SYSTEM; WILD TYPE;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; ANIMALS, GENETICALLY MODIFIED; BRAIN CHEMISTRY; DISEASE MODELS, ANIMAL; HUMANS; IMMUNOHISTOCHEMISTRY; KIDNEY; LUNG; MICE; MYOCARDIUM; RATS; RATS, INBRED F344; TRANSGENES;

EID: 41049100674     PISSN: None     EISSN: 14712202     Source Type: Journal    
DOI: 10.1186/1471-2202-9-28     Document Type: Article

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