Amyloid-β precursor protein mediates neuronal toxicity of amyloid β through Go protein activation

Neurobiology of Aging

Volumn 30, Issue 9, 2009, Pages 1379-1392

  Sola Vigo, Francisco ^a   Kedikian, Gabriela ^a   Heredia, Lorena ^a   Heredia, Florencia ^a   Añel, Alberto Díaz ^a   Rosa, Alberto Luis ^a   Lorenzo, Alfredo ^a,b  

^a INSTITUTO DE INVESTIGACIÓN MÉDICA MERCEDES Y MARTÍN FERREYRA   (Argentina)

^b UNIVERSIDAD NACIONAL DE CÓRDOBA   (Argentina)

Author keywords

Alzheimer's disease (AD); Amyloid beta (A ); Amyloid precursor protein (APP); Go protein; Neuronal degeneration; Pertussis toxin (PTX)

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; GO PROTEIN; GUANINE NUCLEOTIDE BINDING PROTEIN; PERTUSSIS TOXIN; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ANIMAL CELL; ARTICLE; BINDING SITE; CONTROLLED STUDY; HIPPOCAMPUS; NERVE CELL DEGENERATION; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN PROTEIN INTERACTION; RAT;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; BINDING SITES; BRAIN; CELLS, CULTURED; GTP-BINDING PROTEIN ALPHA SUBUNITS, GI-GO; HIPPOCAMPUS; HUMANS; NERVE DEGENERATION; NEURONS; PERTUSSIS TOXIN; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RATS;

EID: 67650498978     PISSN: 01974580     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neurobiolaging.2007.11.017     Document Type: Article

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