-
2
-
-
0025238653
-
Defined neurofilament, τ, and β-amyloid precursor protein epitopes distinguish Alzheimer from non-Alzheimer senile plaques
-
Arai H, Lee VM, Otvos L Jr, et al. Defined neurofilament, τ, and β-amyloid precursor protein epitopes distinguish Alzheimer from non-Alzheimer senile plaques. Proc Natl Acad Sci U S A. 1990;87:2249-2253.
-
(1990)
Proc Natl Acad Sci U S A
, vol.87
, pp. 2249-2253
-
-
Arai, H.1
Lee, V.M.2
Otvos Jr., L.3
-
3
-
-
0028227962
-
Role of abnormally phosphorylated τ in the breakdown of microtubules in Alzheimer disease
-
Alonso AC, Zaidi T, Grundke-lqbal I, Iqbal K. Role of abnormally phosphorylated τ in the breakdown of microtubules in Alzheimer disease. Proc Natl Acad Sci U S A. 1994;91:5562-5566.
-
(1994)
Proc Natl Acad Sci U S A
, vol.91
, pp. 5562-5566
-
-
Alonso, A.C.1
Zaidi, T.2
Grundke-lqbal, I.3
Iqbal, K.4
-
4
-
-
0023132387
-
Characterization and chromosomal localization of a cDNA encoding brain amyloid of Alzheimer's disease
-
Goldgaber D, Lerman MI, McBride OW, Saffiotti U, Gajdusek DC. Characterization and chromosomal localization of a cDNA encoding brain amyloid of Alzheimer's disease. Science. 1987;235:877-880.
-
(1987)
Science
, vol.235
, pp. 877-880
-
-
Goldgaber, D.1
Lerman, M.I.2
McBride, O.W.3
Saffiotti, U.4
Gajdusek, D.C.5
-
5
-
-
0023109592
-
Amyloid beta protein gene: cDNA, mRNA distribution, and genetic linkage nearthe Alzheimer locus
-
Tanzi RE, Gusella JF, Watkins PC, et al. Amyloid beta protein gene: cDNA, mRNA distribution, and genetic linkage nearthe Alzheimer locus. Science. 1987;235:880-884.
-
(1987)
Science
, vol.235
, pp. 880-884
-
-
Tanzi, R.E.1
Gusella, J.F.2
Watkins, P.C.3
-
6
-
-
0023105114
-
The precursor of Alzheimer's disease A4 protein resembles a cell surface receptor
-
Kang J, Lemaire HG, Unterbeck A, et al. The precursor of Alzheimer's disease A4 protein resembles a cell surface receptor. Nature. 1987;325:733-736.
-
(1987)
Nature
, vol.325
, pp. 733-736
-
-
Kang, J.1
Lemaire, H.G.2
Unterbeck, A.3
-
7
-
-
0023870043
-
A new A4 amyloid mRNA contains a domain homologous to serine proteinase inhibitors
-
Ponte P, Gonzalez-DeWhitt P, Schilling J, et al. A new A4 amyloid mRNA contains a domain homologous to serine proteinase inhibitors. Nature. 1988;331:525-527.
-
(1988)
Nature
, vol.331
, pp. 525-527
-
-
Ponte, P.1
Gonzalez-DeWhitt, P.2
Schilling, J.3
-
8
-
-
0023850791
-
Protease inhibitor domain encoded by an amyloid protein precursor mRNA associated with Alzheimer's disease
-
Tanzi RE, McClatchey AL, Lampert ED, Villa-Komaroff L, Gusella JF, Neve RL. Protease inhibitor domain encoded by an amyloid protein precursor mRNA associated with Alzheimer's disease. Nature. 1988;331:528-530.
-
(1988)
Nature
, vol.331
, pp. 528-530
-
-
Tanzi, R.E.1
McClatchey, A.L.2
Lampert, E.D.3
Villa-Komaroff, L.4
Gusella, J.F.5
Neve, R.L.6
-
9
-
-
0023872043
-
A novel precursor of Alzheimer's disease amyloid protein shows protease inhibitory activity
-
Kitaguchi N, Takahashi Y, Takushima Y, Shiojiri S, Ito H. A novel precursor of Alzheimer's disease amyloid protein shows protease inhibitory activity. Nature. 1988;331:530-532.
-
(1988)
Nature
, vol.331
, pp. 530-532
-
-
Kitaguchi, N.1
Takahashi, Y.2
Takushima, Y.3
Shiojiri, S.4
Ito, H.5
-
10
-
-
0001067847
-
Beta amyloid precursor protein of Alzheimer's disease occurs as 110- to 135-kDa membrane-associated proteins in neural and non-neural tissues
-
Selkoe DJ, Podlisny MB, Joachim CL, et al. Beta amyloid precursor protein of Alzheimer's disease occurs as 110-to 135-kDa membrane-associated proteins in neural and non-neural tissues. Proc Natl Acad Sci U S A. 1988;85:7341-7345.
-
(1988)
Proc Natl Acad Sci U S A
, vol.85
, pp. 7341-7345
-
-
Selkoe, D.J.1
Podlisny, M.B.2
Joachim, C.L.3
-
11
-
-
0025373986
-
Expression of β-amyloid protein precursor mRNAs
-
Golde TE, Estes S, Usiak M, Younkin L, Younkin S. Expression of β-amyloid protein precursor mRNAs. Neuron. 1990;4:253-267.
-
(1990)
Neuron.
, vol.4
, pp. 253-267
-
-
Golde, T.E.1
Estes, S.2
Usiak, M.3
Younkin, L.4
Younkin, S.5
-
13
-
-
0024451476
-
Amyloid beta protein deposition in tissues other than brain in Alzheimer's disease
-
Joachim CL, Mori H, Selkoe D. Amyloid beta protein deposition in tissues other than brain in Alzheimer's disease. Nature. 1989;341:226-230.
-
(1989)
Nature
, vol.341
, pp. 226-230
-
-
Joachim, C.L.1
Mori, H.2
Selkoe, D.3
-
14
-
-
0024313844
-
Molecular pathology of amyloidogenic proteins and the role of amyloidosis in Alzheimer's disease
-
Selkoe DJ. Molecular pathology of amyloidogenic proteins and the role of amyloidosis in Alzheimer's disease. Neurobiol Aging. 1989;10:387-395.
-
(1989)
Neurobiol Aging
, vol.10
, pp. 387-395
-
-
Selkoe, D.J.1
-
15
-
-
0025341743
-
Microangiopathy, the vascular basement membrane and Alzheimer's disease: A review
-
Perlmutter LS, Chang C. Microangiopathy, the vascular basement membrane and Alzheimer's disease: a review. Brain Res Bull. 1990;24:677-686.
-
(1990)
Brain Res Bull.
, vol.24
, pp. 677-686
-
-
Perlmutter, L.S.1
Chang, C.2
-
16
-
-
0028983422
-
Is the clustering of β-amyloid (Aβ) deposits in the frontal cortex of Alzheimer patients determined by blood vessels?
-
Armstrong RA. Is the clustering of β-amyloid (Aβ) deposits in the frontal cortex of Alzheimer patients determined by blood vessels? Neurosci Lett. 1995;195:121-124.
-
(1995)
Neurosci Lett.
, vol.195
, pp. 121-124
-
-
Armstrong, R.A.1
-
17
-
-
0029670094
-
Beta-amyloid-mediated vasoactivity and vascular endothelial damage
-
Thomas T, Thomas G, McLendon C, Sutton T, Mullan M. Beta-amyloid-mediated vasoactivity and vascular endothelial damage. Nature. 1996;380:168-171.
-
(1996)
Nature
, vol.380
, pp. 168-171
-
-
Thomas, T.1
Thomas, G.2
McLendon, C.3
Sutton, T.4
Mullan, M.5
-
18
-
-
0029040554
-
Proteolytic processing of Alzheimer's disease βA4 amyloid precursor protein in human platelets
-
Li QX, Evin G, Small DH, Multhaup G, Beyreuther K, Masters CL. Proteolytic processing of Alzheimer's disease βA4 amyloid precursor protein in human platelets. J Biol Chem. 1995;270:14140-14147.
-
(1995)
J Biol Chem.
, vol.270
, pp. 14140-14147
-
-
Li, Q.X.1
Evin, G.2
Small, D.H.3
Multhaup, G.4
Beyreuther, K.5
Masters, C.L.6
-
19
-
-
0029824027
-
Intra-arterial infusion of [I-125]A-β-1-40 labels amyloid deposits in the aged primate brain in vivo
-
Ghilardi JR, Catton M, Stimson ER, et al. Intra-arterial infusion of [I-125]A-β-1-40 labels amyloid deposits in the aged primate brain in vivo. Neuroreport. 1996; 7:2607-2611.
-
(1996)
Neuroreport
, vol.7
, pp. 2607-2611
-
-
Ghilardi, J.R.1
Catton, M.2
Stimson, E.R.3
-
20
-
-
0031561796
-
The putative blood-brain barrier transporter for the β-amyloid binding protein apolipoprotein J is saturated at physiological concentrations
-
Shayo M, McLay RN, Kastin AJ, Bands WA. The putative blood-brain barrier transporter for the β-amyloid binding protein apolipoprotein J is saturated at physiological concentrations. Life Sci. 1997;60:PL115-PL118.
-
(1997)
Life Sci.
, vol.60
-
-
Shayo, M.1
McLay, R.N.2
Kastin, A.J.3
Bands, W.A.4
-
21
-
-
0025171335
-
The amyloid precursor protein of Alzheimer's disease is released by human platelets
-
Bush AL, Martins RN, Rumble B, et al. The amyloid precursor protein of Alzheimer's disease is released by human platelets. J Biol Chem. 1990;265:15977-15983.
-
(1990)
J Biol Chem.
, vol.265
, pp. 15977-15983
-
-
Bush, A.L.1
Martins, R.N.2
Rumble, B.3
-
22
-
-
0026600598
-
Detection of different isoforms patterns of the β-amyloid precursor protein in human platelets and lymphocytes
-
Schlossmacher MG, Ostaszewski BL, Hecker LI, et al. Detection of different isoforms patterns of the β-amyloid precursor protein in human platelets and lymphocytes. Neurobiol Aging. 1992;13:421-434.
-
(1992)
Neurobiol Aging
, vol.13
, pp. 421-434
-
-
Schlossmacher, M.G.1
Ostaszewski, B.L.2
Hecker, L.I.3
-
24
-
-
0025563206
-
Intact Alzheimer amyloid precursor protein (APP) is present in platelet membrane and is encoded by platelet mRNA
-
Gardella JE, Ghiso J, Gorgone GA, et al. Intact Alzheimer amyloid precursor protein (APP) is present in platelet membrane and is encoded by platelet mRNA. Biochem Biophys Res Commun. 1990;173:1292-1298.
-
(1990)
Biochem Biophys Res Commun.
, vol.173
, pp. 1292-1298
-
-
Gardella, J.E.1
Ghiso, J.2
Gorgone, G.A.3
-
25
-
-
0026594114
-
Characterization of Alzheimer amyloid precursor protein transcripts in platelets and megakaryocytes
-
Gardella JE, Gorgone GA, Newman P, Frangione B, Gorevic PD. Characterization of Alzheimer amyloid precursor protein transcripts in platelets and megakaryocytes. Neurosci Lett. 1992;138:229-232.
-
(1992)
Neurosci Lett.
, vol.138
, pp. 229-232
-
-
Gardella, J.E.1
Gorgone, G.A.2
Newman, P.3
Frangione, B.4
Gorevic, P.D.5
-
27
-
-
0025371509
-
Protease nexin II (amyloid β protein precursor): A platelet α-granule protein
-
Van Nostrand WE, Schmaier AH, Farrow JS, Cunningham DD. Protease nexin II (amyloid β protein precursor): a platelet α-granule protein. Science. 1990;248:745-748.
-
(1990)
Science
, vol.248
, pp. 745-748
-
-
Van Nostrand, W.E.1
Schmaier, A.H.2
Farrow, J.S.3
Cunningham, D.D.4
-
28
-
-
0025365401
-
Platelet coagulation factor Xla-inhibitor, a form of Alzheimer amyloid precursor protein
-
Smith RP, Higuchi DA, Broze GJ Jr. Platelet coagulation factor Xla-inhibitor, a form of Alzheimer amyloid precursor protein. Science. 1990;248:1126-1128.
-
(1990)
Science
, vol.248
, pp. 1126-1128
-
-
Smith, R.P.1
Higuchi, D.A.2
Broze Jr., G.J.3
-
29
-
-
0027170518
-
Non-age related differences in thrombin responses by platelets from male patients with advanced Alzheimer's disease
-
Davies TA, Fine RE, Johnson RJ, et al. Non-age related differences in thrombin responses by platelets from male patients with advanced Alzheimer's disease. Biochem Biophys Res Commun. 1993;194:537-543.
-
(1993)
Biochem Biophys Res Commun.
, vol.194
, pp. 537-543
-
-
Davies, T.A.1
Fine, R.E.2
Johnson, R.J.3
-
30
-
-
0030788580
-
Activated Alzheimer disease platelets retain more β amyloid precursor protein
-
Davies TA, Long HJ, Sgro K, et al. Activated Alzheimer disease platelets retain more β amyloid precursor protein. Neurobiol Aging. 1997;18:147-153.
-
(1997)
Neurobiol Aging
, vol.18
, pp. 147-153
-
-
Davies, T.A.1
Long, H.J.2
Sgro, K.3
-
31
-
-
18544412894
-
Moderate and advanced Alzheimer's patients exhibit platelet activation differences
-
Davies TA, Long HJ, Tibbles HE, et al. Moderate and advanced Alzheimer's patients exhibit platelet activation differences. Neurobiol Aging. 1997;18:155-162.
-
(1997)
Neurobiol Aging
, vol.18
, pp. 155-162
-
-
Davies, T.A.1
Long, H.J.2
Tibbles, H.E.3
-
32
-
-
0029819924
-
Abnormal pattern of platelet APP isoforms in Alzheimer disease and Down syndrome
-
Di Luca M, Pastorino L, Cattabeni F, et al. Abnormal pattern of platelet APP isoforms in Alzheimer disease and Down syndrome. Arch Neurol. 1996;53:1162-1166.
-
(1996)
Arch Neurol.
, vol.53
, pp. 1162-1166
-
-
Di Luca, M.1
Pastorino, L.2
Cattabeni, F.3
-
33
-
-
0031047350
-
Altered amyloid protein processing in platelets of patients with Alzheimer disease
-
Rosenberg RN, Bashin F, Fosmire JA, et al. Altered amyloid protein processing in platelets of patients with Alzheimer disease. Arch Neurol. 1997;54:139-144.
-
(1997)
Arch Neurol.
, vol.54
, pp. 139-144
-
-
Rosenberg, R.N.1
Bashin, F.2
Fosmire, J.A.3
-
34
-
-
0023635124
-
Family study of platelet membrane fluidity in Alzheimer's disease
-
Zubenko GS, Wusylko M, Cohen BM, Boller F, Teply I. Family study of platelet membrane fluidity in Alzheimer's disease. Science. 1987;238:539-542.
-
(1987)
Science
, vol.238
, pp. 539-542
-
-
Zubenko, G.S.1
Wusylko, M.2
Cohen, B.M.3
Boller, F.4
Teply, I.5
-
35
-
-
0021271971
-
Clinical diagnosis of Alzheimer's disease
-
McKhann G, Drachman D, Folstein M, Katzman R, Price D, Stadlan EM. Clinical diagnosis of Alzheimer's disease. Neurology. 1984;34:939-944.
-
(1984)
Neurology
, vol.34
, pp. 939-944
-
-
McKhann, G.1
Drachman, D.2
Folstein, M.3
Katzman, R.4
Price, D.5
Stadlan, E.M.6
-
36
-
-
0029080136
-
Abnormalities of c-AMP-dependent endogenous phosphorylation in platelets from patients with bipolar disorders
-
Perez J, Zanardi R, Mori S, Gasperini M, Smeraldi E, Racagni G. Abnormalities of c-AMP-dependent endogenous phosphorylation in platelets from patients with bipolar disorders. Am J Psychiatry. 1995;152:1204-1206.
-
(1995)
Am J Psychiatry
, vol.152
, pp. 1204-1206
-
-
Perez, J.1
Zanardi, R.2
Mori, S.3
Gasperini, M.4
Smeraldi, E.5
Racagni, G.6
-
38
-
-
0030921730
-
Increased secretion of the amino-terminal fragment of amyloid precursor protein in brains of rats with constitutive up-regulation of protein kinase C
-
Caputi A, Barindelli S, Pastorino L, et al. Increased secretion of the amino-terminal fragment of amyloid precursor protein in brains of rats with constitutive up-regulation of protein kinase C. J Neurochem. 1997;68:2523-2529.
-
(1997)
J Neurochem.
, vol.68
, pp. 2523-2529
-
-
Caputi, A.1
Barindelli, S.2
Pastorino, L.3
-
39
-
-
0027240503
-
Isolation and characterization of APLP 2 encoding a homologue of the Alzheimer's associated amyloid β-protein precursor
-
Wasco W, Gurubhagavatula S, Paradis MD, et al. Isolation and characterization of APLP 2 encoding a homologue of the Alzheimer's associated amyloid β-protein precursor. Nat Genet. 1993;5:95-100.
-
(1993)
Nat Genet.
, vol.5
, pp. 95-100
-
-
Wasco, W.1
Gurubhagavatula, S.2
Paradis, M.D.3
-
40
-
-
0020040238
-
A new clinical scale for the staging of dementia
-
Hughes CP, Berg L, Danziger WL, Coben LA, Martin RL. A new clinical scale for the staging of dementia. Br J Psychiatry. 1982;140:566-572.
-
(1982)
Br J Psychiatry
, vol.140
, pp. 566-572
-
-
Hughes, C.P.1
Berg, L.2
Danziger, W.L.3
Coben, L.A.4
Martin, R.L.5
-
41
-
-
0016823810
-
"Mini-Mental State": A practical method for grading the cognitive state of patients for the clinician
-
Folstein MF, Folstein SE, McHugh PR. "Mini-Mental State": a practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res. 1975; 12:189-198.
-
(1975)
J Psychiatr Res.
, vol.12
, pp. 189-198
-
-
Folstein, M.F.1
Folstein, S.E.2
McHugh, P.R.3
-
42
-
-
0031028485
-
Collection and normal levels of the amyloid precursor protein in plasma
-
Whyte S, Wilson N, Currie J, et al. Collection and normal levels of the amyloid precursor protein in plasma. Ann Neurol. 1997;41:121-124.
-
(1997)
Ann Neurol.
, vol.41
, pp. 121-124
-
-
Whyte, S.1
Wilson, N.2
Currie, J.3
-
43
-
-
0028935052
-
Elevation of microtubule-associated protein τ in the cerebrospinal fluid of patients with Alzheimer's disease
-
Vigo-Pelfrey C, Seubert P, Barbour R, et al. Elevation of microtubule-associated protein τ in the cerebrospinal fluid of patients with Alzheimer's disease. Neurology. 1995;45:788-793.
-
(1995)
Neurology
, vol.45
, pp. 788-793
-
-
Vigo-Pelfrey, C.1
Seubert, P.2
Barbour, R.3
-
44
-
-
0028982454
-
Reduction of β-amyloid peptide 42 in the cerebrospinal fluid of patients with Alzheimer's disease
-
Motter R, Vigo-Pelfrey C, Kholodenko D, Barbour R, Johnson-Wood K, Galasko D. Reduction of β-amyloid peptide 42 in the cerebrospinal fluid of patients with Alzheimer's disease. Ann Neurol. 1995;38:643-648.
-
(1995)
Ann Neurol.
, vol.38
, pp. 643-648
-
-
Motter, R.1
Vigo-Pelfrey, C.2
Kholodenko, D.3
Barbour, R.4
Johnson-Wood, K.5
Galasko, D.6
-
45
-
-
0028982840
-
Decreased α-secretase-cleaved amyloid precursor protein as a diagnostic marker for Alzheimer's disease
-
Lannfelt L, Basun H, Wahlund LO, Rowe BA, Wagner SL. Decreased α-secretase-cleaved amyloid precursor protein as a diagnostic marker for Alzheimer's disease. Nature. 1995;1:829-832.
-
(1995)
Nature
, vol.1
, pp. 829-832
-
-
Lannfelt, L.1
Basun, H.2
Wahlund, L.O.3
Rowe, B.A.4
Wagner, S.L.5
|