-
1
-
-
0027267493
-
Inhibition of kinesin synthesis and rapid anterograde axonal transport in vivo by an antisense oligonucleotide
-
Amaratunga A., Morin P. J., Kosik K. S., and, Fine R. E., (1993) Inhibition of kinesin synthesis and rapid anterograde axonal transport in vivo by an antisense oligonucleotide. J. Biol. Chem. 268, 17427-17430. (Pubitemid 23236984)
-
(1993)
Journal of Biological Chemistry
, vol.268
, Issue.23
, pp. 17427-17430
-
-
Amaratunga, A.1
Morin, P.J.2
Kosik, K.S.3
Fine, R.E.4
-
2
-
-
26444607532
-
Neuronal sorting protein-related receptor sorLA/LR11 regulates processing of the amyloid precursor protein
-
DOI 10.1073/pnas.0503689102
-
Andersen O. M., Reiche J., Schmidt V., et al. (2005) Neuronal sorting protein-related receptor sorLA/LR11 regulates processing of the amyloid precursor protein. Proc. Natl Acad. Sci. USA 102, 13461-13466. (Pubitemid 41420870)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.38
, pp. 13461-13466
-
-
Andersen, O.M.1
Reiche, J.2
Schmidt, V.3
Gotthardt, M.4
Spoelgen, R.5
Behlke, J.6
Von Arnim, C.A.F.7
Breiderhoff, T.8
Jansen, P.9
Wu, X.10
Bales, K.R.11
Cappai, R.12
Masters, C.L.13
Gliemann, J.14
Mufson, E.J.15
Hyman, B.T.16
Paul, S.M.17
Nykjsaer, A.18
Willnow, T.E.19
-
3
-
-
33749176134
-
GGA1 acts as a spatial switch altering amyloid precursor protein trafficking and processing
-
DOI 10.1523/JNEUROSCI.2290-06.2006
-
von Arnim C. A., Spoelgen R., Peltan I. D., et al. (2006) GGA1 acts as a spatial switch altering amyloid precursor protein trafficking and processing. J. Neurosci. 26, 9913-9922. (Pubitemid 44477153)
-
(2006)
Journal of Neuroscience
, vol.26
, Issue.39
, pp. 9913-9922
-
-
Von Arnim, C.A.F.1
Spoelgen, R.2
Peltan, I.D.3
Deng, M.4
Courchesne, S.5
Koker, M.6
Matsui, T.7
Kowa, H.8
Lichtenthaler, S.F.9
Irizarry, M.C.10
Hyman, B.T.11
-
4
-
-
0346435103
-
Generation of the β-Amyloid Peptide and the Amyloid Precursor Protein C-terminal Fragment γ Are Potentiated by FE65L1
-
DOI 10.1074/jbc.M309561200
-
Chang Y., Tesco G., Jeong W. J., Lindsley L., Eckman E. A., Eckman C. B., Tanzi R. E., and, Guenette S. Y., (2003) Generation of the beta-amyloid peptide and the amyloid precursor protein C-terminal fragment gamma are potentiated by FE65L1. J. Biol. Chem. 278, 51100-51107. (Pubitemid 38020345)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.51
, pp. 51100-51107
-
-
Chang, Y.1
Tesco, G.2
Jeong, W.J.3
Lindsley, L.4
Eckman, E.A.5
Eckman, C.B.6
Tanzi, R.E.7
Guenette, S.Y.8
-
5
-
-
79960910811
-
Effects of heparin and enoxaparin on APP processing and Abeta production in primary cortical neurons from Tg2576 mice
-
Cui H., Hung A. C., Klaver D. W., Suzuki T., Freeman C., Narkowicz C., Jacobson G. A., and, Small D. H., (2011) Effects of heparin and enoxaparin on APP processing and Abeta production in primary cortical neurons from Tg2576 mice. PLoS One 6, e23007.
-
(2011)
PLoS One
, vol.6
-
-
Cui, H.1
Hung, A.C.2
Klaver, D.W.3
Suzuki, T.4
Freeman, C.5
Narkowicz, C.6
Jacobson, G.A.7
Small, D.H.8
-
6
-
-
0030726894
-
Huntingtin-associated protein 1 (HAP1) interacts with the p150(Glued) subunit of dynactin
-
Engelender S., Sharp A. H., Colomer V., Tokito M. K., Lanahan A., Worley P., Holzbaur E. L., and, Ross C. A., (1997) Huntingtin-associated protein 1 (HAP1) interacts with the p150Glued subunit of dynactin. Hum. Mol. Genet. 6, 2205-2212. (Pubitemid 27501070)
-
(1997)
Human Molecular Genetics
, vol.6
, Issue.13
, pp. 2205-2212
-
-
Engelender, S.1
Sharp, A.H.2
Colomer, V.3
Tokito, M.K.4
Lanahan, A.5
Worley, P.6
Holzbaur, E.L.F.7
Ross, C.A.8
-
7
-
-
0141866643
-
Long term association of the cytokine receptor gp130 and the janus kinase Jak1 revealed by FRAP analysis
-
DOI 10.1074/jbc.M303347200
-
Giese B., Au-Yeung C. K., Herrmann A., et al. (2003) Long term association of the cytokine receptor gp130 and the Janus kinase Jak1 revealed by FRAP analysis. J. Biol. Chem. 278, 39205-39213. (Pubitemid 37221824)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.40
, pp. 39205-39213
-
-
Giese, B.1
Au-Yeung, C.-K.2
Herrmann, A.3
Diefenbach, S.4
Haan, C.5
Kuster, A.6
Wortmann, S.B.7
Roderburg, C.8
Heinrich, P.C.9
Behrmann, I.10
Muller-Newen, G.11
-
8
-
-
0026088977
-
Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease
-
Goate A., Chartier-Harlin M. C., Mullan M., et al. (1991) Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease. Nature 349, 704-706. (Pubitemid 21912142)
-
(1991)
Nature
, vol.349
, Issue.6311
, pp. 704-706
-
-
Goate, A.1
Chartier-Harlin, M.-C.2
Mullan, M.3
Brown, J.4
Crawford, F.5
Fldani, L.6
Giuffra, L.7
Haynes, A.8
Irving, N.9
James, L.10
Mant, R.11
Newton, P.12
Rooke, K.13
Roques, P.14
Talbot, C.15
Pericak-Vance, M.16
Roses, A.17
Williamson, R.18
Rossor, M.19
Owen, M.20
Hardy, J.21
more..
-
9
-
-
0027333557
-
Cellular processing of beta-amyloid precursor protein and the genesis of amyloid beta-peptide
-
Haass C., and, Selkoe D. J., (1993) Cellular processing of beta-amyloid precursor protein and the genesis of amyloid beta-peptide. Cell 75, 1039-1042.
-
(1993)
Cell
, vol.75
, pp. 1039-1042
-
-
Haass, C.1
Selkoe, D.J.2
-
10
-
-
0025899041
-
Amyloid deposition as the central event in the aetiology of Alzheimer's disease
-
Hardy J., and, Allsop D., (1991) Amyloid deposition as the central event in the aetiology of Alzheimer's disease. Trends Pharmacol. Sci. 12, 383-388.
-
(1991)
Trends Pharmacol. Sci.
, vol.12
, pp. 383-388
-
-
Hardy, J.1
Allsop, D.2
-
11
-
-
0026597063
-
Alzheimer's disease: The amyloid cascade hypothesis
-
Hardy J. A., and, Higgins G. A., (1992) Alzheimer's disease: the amyloid cascade hypothesis. Science 256, 184-185.
-
(1992)
Science
, vol.256
, pp. 184-185
-
-
Hardy, J.A.1
Higgins, G.A.2
-
12
-
-
15744380393
-
GGA proteins mediate the recycling pathway of memapsin 2 (BACE)
-
DOI 10.1074/jbc.M411296200
-
He X., Li F., Chang W. P., and, Tang J., (2005) GGA proteins mediate the recycling pathway of memapsin 2 (BACE). J. Biol. Chem. 280, 11696-11703. (Pubitemid 40418483)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.12
, pp. 11696-11703
-
-
He, X.1
Li, F.2
Chang, W.-P.3
Tang, J.4
-
13
-
-
80055115985
-
Preparation of dissociated mouse cortical neuron cultures
-
Hilgenberg L. G., and, Smith M. A., (2007) Preparation of dissociated mouse cortical neuron cultures. J. Vis. Exp. 10, 562.
-
(2007)
J. Vis. Exp.
, vol.10
, pp. 562
-
-
Hilgenberg, L.G.1
Smith, M.A.2
-
14
-
-
79952170352
-
Effect of metal chelators on gamma-secretase indicates that calcium and magnesium ions facilitate cleavage of Alzheimer amyloid precursor substrate
-
Ho M., Hoke D. E., Chua Y. J., Li Q. X., Culvenor J. G., Masters C., White A. R., and, Evin G., (2010) Effect of metal chelators on gamma-secretase indicates that calcium and magnesium ions facilitate cleavage of Alzheimer amyloid precursor substrate. Int. J. Alzheimers Dis. 2011, 950932.
-
(2010)
Int. J. Alzheimers Dis.
, vol.2011
, pp. 950932
-
-
Ho, M.1
Hoke, D.E.2
Chua, Y.J.3
Li, Q.X.4
Culvenor, J.G.5
Masters, C.6
White, A.R.7
Evin, G.8
-
15
-
-
67649336940
-
Essential role of Hrs in endocytic recycling of full-length TrkB receptor but not its isoform TrkB.T1
-
Huang S. H., Zhao L., Sun Z. P., Li X. Z., Geng Z., Zhang K. D., Chao M. V., and, Chen Z. Y., (2009) Essential role of Hrs in endocytic recycling of full-length TrkB receptor but not its isoform TrkB.T1. J. Biol. Chem. 284, 15126-15136.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 15126-15136
-
-
Huang, S.H.1
Zhao, L.2
Sun, Z.P.3
Li, X.Z.4
Geng, Z.5
Zhang, K.D.6
Chao, M.V.7
Chen, Z.Y.8
-
16
-
-
0026767361
-
Increased expression of beta-amyloid precursor protein during neuronal differentiation is not accompanied by secretory cleavage
-
Hung A. Y., Koo E. H., Haass C., and, Selkoe D. J., (1992) Increased expression of beta-amyloid precursor protein during neuronal differentiation is not accompanied by secretory cleavage. Proc. Natl Acad. Sci. USA 89, 9439-9443.
-
(1992)
Proc. Natl Acad. Sci. USA
, vol.89
, pp. 9439-9443
-
-
Hung, A.Y.1
Koo, E.H.2
Haass, C.3
Selkoe, D.J.4
-
17
-
-
0034721842
-
Maturation and endosomal targeting of beta-site amyloid precursor protein-cleaving enzyme the Alzheimer's disease beta-secretase
-
Huse J. T., Pijak D. S., Leslie G. J., Lee V. M., and, Doms R. W., (2000) Maturation and endosomal targeting of beta-site amyloid precursor protein-cleaving enzyme The Alzheimer's disease beta-secretase. J. Biol. Chem. 275, 33729-33737.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 33729-33737
-
-
Huse, J.T.1
Pijak, D.S.2
Leslie, G.J.3
Lee, V.M.4
Doms, R.W.5
-
18
-
-
0038603918
-
A scaffold protein JIP-1b enhances amyloid precursor protein phosphorylation by JNK and its association with kinesin light chain 1
-
DOI 10.1074/jbc.M212160200
-
Inomata H., Nakamura Y., Hayakawa A., Takata H., Suzuki T., Miyazawa K., and, Kitamura N., (2003) A scaffold protein JIP-1b enhances amyloid precursor protein phosphorylation by JNK and its association with kinesin light chain 1. J. Biol. Chem. 278, 22946-22955. (Pubitemid 36830359)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.25
, pp. 22946-22955
-
-
Inomata, H.1
Nakamura, Y.2
Hayakawa, A.3
Takata, H.4
Suzuki, T.5
Miyazawa, K.6
Kitamura, N.7
-
19
-
-
77956215864
-
Regulation of amyloid precursor protein processing by the Beclin 1 complex
-
Jaeger P. A., Pickford F., Sun C. H., Lucin K. M., Masliah E., and, Wyss-Coray T., (2010) Regulation of amyloid precursor protein processing by the Beclin 1 complex. PLoS One 5, e11102.
-
(2010)
PLoS One
, vol.5
-
-
Jaeger, P.A.1
Pickford, F.2
Sun, C.H.3
Lucin, K.M.4
Masliah, E.5
Wyss-Coray, T.6
-
20
-
-
0033636136
-
Axonal transport of amyloid precursor protein is mediated by direct binding to the kinesin light chain subunit of kinesin-I
-
Kamal A., Stokin G. B., Yang Z., Xia C. H., and, Goldstein L. S., (2000) Axonal transport of amyloid precursor protein is mediated by direct binding to the kinesin light chain subunit of kinesin-I. Neuron 28, 449-459.
-
(2000)
Neuron
, vol.28
, pp. 449-459
-
-
Kamal, A.1
Stokin, G.B.2
Yang, Z.3
Xia, C.H.4
Goldstein, L.S.5
-
21
-
-
4344624896
-
Huntingtin-associated protein 1 regulates inhibitory synaptic transmission by modulating γ-aminobutyric acid type A receptor membrane trafficking
-
DOI 10.1073/pnas.0401860101
-
Kittler J. T., Thomas P., Tretter V., Bogdanov Y. D., Haucke V., Smart T. G., and, Moss S. J., (2004) Huntingtin-associated protein 1 regulates inhibitory synaptic transmission by modulating gamma-aminobutyric acid type A receptor membrane trafficking. Proc. Natl Acad. Sci. USA 101, 12736-12741. (Pubitemid 39122092)
-
(2004)
Proceedings of the National Academy of Sciences of the United States of America
, vol.101
, Issue.34
, pp. 12736-12741
-
-
Kittler, J.T.1
Thomas, P.2
Tretter, V.3
Bogdanov, Y.D.4
Haucke, V.5
Smart, T.G.6
Moss, S.J.7
-
22
-
-
0032561463
-
Mutation at the processing site of chicken low density lipoprotein receptor-related protein impairs efficient endoplasmic reticulum exit, but proteolytic cleavage is not essential for its endocytic functions
-
DOI 10.1074/jbc.273.43.27779
-
Ko K. W., McLeod R. S., Avramoglu R. K., Nimpf J., FitzGerald D. J., Vukmirica J., and, Yao Z., (1998) Mutation at the processing site of chicken low density lipoprotein receptor-related protein impairs efficient endoplasmic reticulum exit, but proteolytic cleavage is not essential for its endocytic functions. J. Biol. Chem. 273, 27779-27785. (Pubitemid 28496063)
-
(1998)
Journal of Biological Chemistry
, vol.273
, Issue.43
, pp. 27779-27785
-
-
Ko, K.W.S.1
McLeod, R.S.2
Avramoglu, R.K.3
Nimpf, J.4
FitzGerald, D.J.5
Vukmirica, J.6
Yao, Z.7
-
23
-
-
0028276801
-
Evidence that production and release of amyloid β-protein involves the endocytic pathway
-
Koo E. H., and, Squazzo S. L., (1994) Evidence that production and release of amyloid beta-protein involves the endocytic pathway. J. Biol. Chem. 269, 17386-17389. (Pubitemid 24218009)
-
(1994)
Journal of Biological Chemistry
, vol.269
, Issue.26
, pp. 17386-17389
-
-
Koo, E.H.1
Squazzo, S.L.2
-
24
-
-
0025056563
-
Precursor of amyloid protein in Alzheimer disease undergoes fast anterograde axonal transport
-
Koo E. H., Sisodia S. S., Archer D. R., Martin L. J., Weidemann A., Beyreuther K., Fischer P., Masters C. L., and, Price D. L., (1990) Precursor of amyloid protein in Alzheimer disease undergoes fast anterograde axonal transport. Proc. Natl Acad. Sci. USA 87, 1561-1565.
-
(1990)
Proc. Natl Acad. Sci. USA
, vol.87
, pp. 1561-1565
-
-
Koo, E.H.1
Sisodia, S.S.2
Archer, D.R.3
Martin, L.J.4
Weidemann, A.5
Beyreuther, K.6
Fischer, P.7
Masters, C.L.8
Price, D.L.9
-
25
-
-
20044396527
-
Axonal transport, amyloid precursor protein, kinesin-1, and the processing apparatus: Revisited
-
DOI 10.1523/JNEUROSCI.3089-04.2005
-
Lazarov O., Morfini G. A., Lee E. B., et al. (2005) Axonal transport, amyloid precursor protein, kinesin-1, and the processing apparatus: revisited. J. Neurosci. 25, 2386-2395. (Pubitemid 40322280)
-
(2005)
Journal of Neuroscience
, vol.25
, Issue.9
, pp. 2386-2395
-
-
Lazarov, O.1
Morfini, G.A.2
Lee, E.B.3
Farah, M.H.4
Szodorai, A.5
DeBoer, S.R.6
Koliatsos, V.E.7
Kins, S.8
Lee, V.M.-Y.9
Wong, P.C.10
Price, D.L.11
Brady, S.T.12
Sisodia, S.S.13
-
26
-
-
45749139570
-
Regulation of Abeta pathology by beclin 1: A protective role for autophagy?
-
Lee J. A., and, Gao F. B., (2008) Regulation of Abeta pathology by beclin 1: a protective role for autophagy? J. Clin. Invest. 118, 2015-2018.
-
(2008)
J. Clin. Invest.
, vol.118
, pp. 2015-2018
-
-
Lee, J.A.1
Gao, F.B.2
-
27
-
-
11144237210
-
HAP1 and intracellular trafficking
-
Li X. J., and, Li S. H., (2005) HAP1 and intracellular trafficking. Trends Pharmacol. Sci. 26, 1-3.
-
(2005)
Trends Pharmacol. Sci.
, vol.26
, pp. 1-3
-
-
Li, X.J.1
Li, S.H.2
-
28
-
-
0028803757
-
A huntingtin-associated protein enriched in brain with implications for pathology
-
Li X. J., Li S. H., Sharp A. H., Nucifora Jr F. C., Schilling G., Lanahan A., Worley P., Snyder S. H., and, Ross C. A., (1995) A huntingtin-associated protein enriched in brain with implications for pathology. Nature 378, 398-402.
-
(1995)
Nature
, vol.378
, pp. 398-402
-
-
Li, X.J.1
Li, S.H.2
Sharp, A.H.3
Nucifora, Jr.F.C.4
Schilling, G.5
Lanahan, A.6
Worley, P.7
Snyder, S.H.8
Ross, C.A.9
-
29
-
-
0032519646
-
Interaction of Huntingtin-associated protein with dynactin P150(Glued)
-
Li S. H., Gutekunst C. A., Hersch S. M., and, Li X. J., (1998) Interaction of huntingtin-associated protein with dynactin P150Glued. J. Neurosci. 18, 1261-1269. (Pubitemid 28082412)
-
(1998)
Journal of Neuroscience
, vol.18
, Issue.4
, pp. 1261-1269
-
-
Li, S.-H.1
Gutekunst, C.-A.2
Hersch, S.M.3
Li, X.-J.4
-
30
-
-
0041632303
-
Lack of huntingtin-associated protein-1 causes neuronal death resembling hypothalamic degeneration in Huntington's disease
-
Li S. H., Yu Z. X., Li C. L., Nguyen H. P., Zhou Y. X., Deng C., and, Li X. J., (2003) Lack of huntingtin-associated protein-1 causes neuronal death resembling hypothalamic degeneration in Huntington's disease. J. Neurosci. 23, 6956-6964. (Pubitemid 36951224)
-
(2003)
Journal of Neuroscience
, vol.23
, Issue.17
, pp. 6956-6964
-
-
Li, S.-H.1
Yu, Z.-X.2
Li, C.-L.3
Nguyen, H.-P.4
Zhou, Y.-X.5
Deng, C.6
Li, X.-J.7
-
31
-
-
77952355400
-
Huntingtin-associated protein-1 deficiency in orexin-producing neurons impairs neuronal process extension and leads to abnormal behavior in mice
-
Lin Y. F., Xu X., Cape A., Li S., and, Li X. J., (2010) Huntingtin-associated protein-1 deficiency in orexin-producing neurons impairs neuronal process extension and leads to abnormal behavior in mice. J. Biol. Chem. 285, 15941-15949.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 15941-15949
-
-
Lin, Y.F.1
Xu, X.2
Cape, A.3
Li, S.4
Li, X.J.5
-
32
-
-
0030779677
-
Cellular actions of β-amyloid precursor protein and its soluble and fibrillogenic derivatives
-
Mattson M. P., (1997) Cellular actions of beta-amyloid precursor protein and its soluble and fibrillogenic derivatives. Physiol. Rev. 77, 1081-1132. (Pubitemid 27459580)
-
(1997)
Physiological Reviews
, vol.77
, Issue.4
, pp. 1081-1132
-
-
Mattson, M.P.1
-
33
-
-
33645642673
-
Interaction of Huntingtin-associated protein-1 with kinesin light chain: Implications in intracellular trafficking in neurons
-
DOI 10.1074/jbc.M509806200
-
McGuire J. R., Rong J., Li S. H., and, Li X. J., (2006) Interaction of Huntingtin-associated protein-1 with kinesin light chain: implications in intracellular trafficking in neurons. J. Biol. Chem. 281, 3552-3559. (Pubitemid 43845972)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.6
, pp. 3552-3559
-
-
McGuire, J.R.1
Rong, J.2
Li, S.-H.3
Li, X.-J.4
-
34
-
-
44449165118
-
Retromer deficiency observed in Alzheimer's disease causes hippocampal dysfunction, neurodegeneration, and Aβ accumulation
-
DOI 10.1073/pnas.0802545105
-
Muhammad A., Flores I., Zhang H., et al. (2008) Retromer deficiency observed in Alzheimer's disease causes hippocampal dysfunction, neurodegeneration, and Abeta accumulation. Proc. Natl Acad. Sci. USA 105, 7327-7332. (Pubitemid 351754477)
-
(2008)
Proceedings of the National Academy of Sciences of the United States of America
, vol.105
, Issue.20
, pp. 7327-7332
-
-
Muhammad, A.1
Flores, I.2
Zhang, H.3
Yu, R.4
Staniszewski, A.5
Planel, E.6
Herman, M.7
Ho, L.8
Kreber, R.9
Honig, L.S.10
Ganetzky, B.11
Duff, K.12
Arancio, O.13
Small, S.A.14
-
35
-
-
48349085043
-
The amyloid precursor protein intracellular domain (AICD) as modulator of gene expression, apoptosis, and cytoskeletal dynamics-relevance for Alzheimer's disease
-
Muller T., Meyer H. E., Egensperger R., and, Marcus K., (2008) The amyloid precursor protein intracellular domain (AICD) as modulator of gene expression, apoptosis, and cytoskeletal dynamics-relevance for Alzheimer's disease. Prog. Neurobiol. 85, 393-406.
-
(2008)
Prog. Neurobiol.
, vol.85
, pp. 393-406
-
-
Muller, T.1
Meyer, H.E.2
Egensperger, R.3
Marcus, K.4
-
36
-
-
77955817279
-
Proteomic identification of sorting nexin 6 as a negative regulator of BACE1-mediated APP processing
-
Okada H., Zhang W., Peterhoff C., Hwang J. C., Nixon R. A., Ryu S. H., and, Kim T. W., (2010) Proteomic identification of sorting nexin 6 as a negative regulator of BACE1-mediated APP processing. FASEB J. 24, 2783-2794.
-
(2010)
FASEB J.
, vol.24
, pp. 2783-2794
-
-
Okada, H.1
Zhang, W.2
Peterhoff, C.3
Hwang, J.C.4
Nixon, R.A.5
Ryu, S.H.6
Kim, T.W.7
-
37
-
-
49549086892
-
A bi-directional carboxypeptidase E-driven transport mechanism controls BDNF vesicle homeostasis in hippocampal neurons
-
Park J. J., Cawley N. X., and, Loh Y. P., (2008) A bi-directional carboxypeptidase E-driven transport mechanism controls BDNF vesicle homeostasis in hippocampal neurons. Mol. Cell. Neurosci. 39, 63-73.
-
(2008)
Mol. Cell. Neurosci.
, vol.39
, pp. 63-73
-
-
Park, J.J.1
Cawley, N.X.2
Loh, Y.P.3
-
38
-
-
0033609449
-
Cleavage of Alzheimer's amyloid precursor protein by alpha-secretase occurs at the surface of neuronal cells
-
Parvathy S., Hussain I., Karran E. H., Turner A. J., and, Hooper N. M., (1999) Cleavage of Alzheimer's amyloid precursor protein by alpha-secretase occurs at the surface of neuronal cells. Biochemistry 38, 9728-9734.
-
(1999)
Biochemistry
, vol.38
, pp. 9728-9734
-
-
Parvathy, S.1
Hussain, I.2
Karran, E.H.3
Turner, A.J.4
Hooper, N.M.5
-
39
-
-
1842532328
-
The role of the endosomal/lysosomal system in amyloid-beta production and the pathophysiology of Alzheimer's disease: Reexamining the spatial paradox from a lysosomal perspective
-
Pasternak S. H., Callahan J. W., and, Mahuran D. J., (2004) The role of the endosomal/lysosomal system in amyloid-beta production and the pathophysiology of Alzheimer's disease: reexamining the spatial paradox from a lysosomal perspective. J. Alzheimers Dis. 6, 53-65. (Pubitemid 38418558)
-
(2004)
Journal of Alzheimer's Disease
, vol.6
, Issue.1
, pp. 53-65
-
-
Pasternak, S.H.1
Callahan, J.W.2
Mahuran, D.J.3
-
40
-
-
67651171367
-
Decreased brain-derived neurotrophic factor depends on amyloid aggregation state in transgenic mouse models of Alzheimer's disease
-
Peng S., Garzon D. J., Marchese M., et al. (2009) Decreased brain-derived neurotrophic factor depends on amyloid aggregation state in transgenic mouse models of Alzheimer's disease. J. Neurosci. 29, 9321-9329.
-
(2009)
J. Neurosci.
, vol.29
, pp. 9321-9329
-
-
Peng, S.1
Garzon, D.J.2
Marchese, M.3
-
41
-
-
45749114895
-
The autophagy-related protein beclin 1 shows reduced expression in early Alzheimer disease and regulates amyloid β accumulation in mice
-
DOI 10.1172/JCI33585
-
Pickford F., Masliah E., Britschgi M., et al. (2008) The autophagy-related protein beclin 1 shows reduced expression in early Alzheimer disease and regulates amyloid beta accumulation in mice. J. Clin. Invest. 118, 2190-2199. (Pubitemid 351872337)
-
(2008)
Journal of Clinical Investigation
, vol.118
, Issue.6
, pp. 2190-2199
-
-
Pickford, F.1
Masliah, E.2
Britschgi, M.3
Lucin, K.4
Narasimhan, R.5
Jaeger, P.A.6
Small, S.7
Spencer, B.8
Rockenstein, E.9
Levine, B.10
Wyss-Coray, T.11
-
42
-
-
77956490621
-
Effects of F/G-actin ratio and actin turn-over rate on NADPH oxidase activity in microglia
-
Rasmussen I., Pedersen L. H., Byg L., Suzuki K., Sumimoto H., and, Vilhardt F., (2010) Effects of F/G-actin ratio and actin turn-over rate on NADPH oxidase activity in microglia. BMC Immunol. 11, 44.
-
(2010)
BMC Immunol.
, vol.11
, pp. 44
-
-
Rasmussen, I.1
Pedersen, L.H.2
Byg, L.3
Suzuki, K.4
Sumimoto, H.5
Vilhardt, F.6
-
43
-
-
33846613222
-
The neuronal sortilin-related receptor SORL1 is genetically associated with Alzheimer disease
-
DOI 10.1038/ng1943, PII NG1943
-
Rogaeva E., Meng Y., Lee J. H., et al. (2007) The neuronal sortilin-related receptor SORL1 is genetically associated with Alzheimer disease. Nat. Genet. 39, 168-177. (Pubitemid 46184347)
-
(2007)
Nature Genetics
, vol.39
, Issue.2
, pp. 168-177
-
-
Rogaeva, E.1
Meng, Y.2
Lee, J.H.3
Gu, Y.4
Kawarai, T.5
Zou, F.6
Katayama, T.7
Baldwin, C.T.8
Cheng, R.9
Hasegawa, H.10
Chen, F.11
Shibata, N.12
Lunetta, K.L.13
Pardossi-Piquard, R.14
Bohm, C.15
Wakutani, Y.16
Cupples, L.A.17
Cuenco, K.T.18
Green, R.C.19
Pinessi, L.20
Rainero, I.21
Sorbi, S.22
Bruni, A.23
Duara, R.24
Friedland, R.P.25
Inzelberg, R.26
Hampe, W.27
Bujo, H.28
Song, Y.-Q.29
Andersen, O.M.30
Willnow, T.E.31
Graff-Radford, N.32
Petersen, R.C.33
Dickson, D.34
Der, S.D.35
Fraser, P.E.36
Schmitt-Ulms, G.37
Younkin, S.38
Mayeux, R.39
Farrer, L.A.40
St. George-Hyslop, P.41
more..
-
44
-
-
33745233087
-
Regulation of intracellular trafficking of huntingtin-associated protein-1 is critical for TrkA protein levels and neurite outgrowth
-
DOI 10.1523/JNEUROSCI.1251-06.2006
-
Rong J., McGuire J. R., Fang Z. H., Sheng G., Shin J. Y., Li S. H., and, Li X. J., (2006) Regulation of intracellular trafficking of huntingtin- associated protein-1 is critical for TrkA protein levels and neurite outgrowth. J. Neurosci. 26, 6019-6030. (Pubitemid 44318368)
-
(2006)
Journal of Neuroscience
, vol.26
, Issue.22
, pp. 6019-6030
-
-
Rong, J.1
McGuire, J.R.2
Fang, Z.-H.3
Sheng, G.4
Shin, J.-Y.5
Li, S.-H.6
Li, X.-J.7
-
45
-
-
33947511907
-
14-3-3 Protein interacts with Huntingtin-associated protein 1 and regulates its trafficking
-
DOI 10.1074/jbc.M609057200
-
Rong J., Li S., Sheng G., Wu M., Coblitz B., Li M., Fu H., and, Li X. J., (2007) 14-3-3 protein interacts with Huntingtin-associated protein 1 and regulates its trafficking. J. Biol. Chem. 282, 4748-4756. (Pubitemid 47100975)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.7
, pp. 4748-4756
-
-
Rong, J.1
Li, S.2
Sheng, G.3
Wu, M.4
Coblitz, B.5
Li, M.6
Fu, H.7
Li, X.-J.8
-
46
-
-
0032945805
-
Crystal structure of the N-terminal, growth factor-like domain of Alzheimer amyloid precursor protein
-
Rossjohn J., Cappai R., Feil S. C., et al. (1999) Crystal structure of the N-terminal, growth factor-like domain of Alzheimer amyloid precursor protein. Nat. Struct. Biol. 6, 327-331.
-
(1999)
Nat. Struct. Biol.
, vol.6
, pp. 327-331
-
-
Rossjohn, J.1
Cappai, R.2
Feil, S.C.3
-
47
-
-
33750823234
-
A peptide zipcode sufficient for anterograde transport within amyloid precursor protein
-
DOI 10.1073/pnas.0607527103
-
Satpute-Krishnan P., DeGiorgis J. A., Conley M. P., Jang M., and, Bearer E. L., (2006) A peptide zipcode sufficient for anterograde transport within amyloid precursor protein. Proc. Natl Acad. Sci. USA 103, 16532-16537. (Pubitemid 44715230)
-
(2006)
Proceedings of the National Academy of Sciences of the United States of America
, vol.103
, Issue.44
, pp. 16532-16537
-
-
Satpute-Krishnan, P.1
DeGiorgis, J.A.2
Conley, M.P.3
Jang, M.4
Bearer, E.L.5
-
48
-
-
40849139207
-
Retromer sorting: A pathogenic pathway in late-onset Alzheimer disease
-
DOI 10.1001/archneurol.2007.64
-
Small S. A., (2008) Retromer sorting: a pathogenic pathway in late-onset Alzheimer disease. Arch. Neurol. 65, 323-328. (Pubitemid 351398517)
-
(2008)
Archives of Neurology
, vol.65
, Issue.3
, pp. 323-328
-
-
Small, S.A.1
-
49
-
-
33749042749
-
Sorting through the Cell Biology of Alzheimer's Disease: Intracellular Pathways to Pathogenesis
-
DOI 10.1016/j.neuron.2006.09.001, PII S0896627306006763
-
Small S. A., and, Gandy S., (2006) Sorting through the cell biology of Alzheimer's disease: intracellular pathways to pathogenesis. Neuron 52, 15-31. (Pubitemid 44466354)
-
(2006)
Neuron
, vol.52
, Issue.1
, pp. 15-31
-
-
Small, S.A.1
Gandy, S.2
-
50
-
-
27744576858
-
Model-guided microarray implicates the retromer complex in Alzheimer's disease
-
DOI 10.1002/ana.20667
-
Small S. A., Kent K., Pierce A., Leung C., Kang M. S., Okada H., Honig L., Vonsattel J. P., and, Kim T. W., (2005) Model-guided microarray implicates the retromer complex in Alzheimer's disease. Ann. Neurol. 58, 909-919. (Pubitemid 41746881)
-
(2005)
Annals of Neurology
, vol.58
, Issue.6
, pp. 909-919
-
-
Small, S.A.1
Kent, K.2
Pierce, A.3
Leung, C.4
Kang, M.S.5
Okada, H.6
Honig, L.7
Vonsattel, J.-P.8
Kim, T.-W.9
-
51
-
-
70949085531
-
APP anterograde transport requires Rab3A GTPase activity for assembly of the transport vesicle
-
Szodorai A., Kuan Y. H., Hunzelmann S., et al. (2009) APP anterograde transport requires Rab3A GTPase activity for assembly of the transport vesicle. J. Neurosci. 29, 14534-14544.
-
(2009)
J. Neurosci.
, vol.29
, pp. 14534-14544
-
-
Szodorai, A.1
Kuan, Y.H.2
Hunzelmann, S.3
-
52
-
-
33747884387
-
Huntingtin-associated protein 1 (HAP1) interacts with androgen receptor (AR) and suppresses SBMA-mutant-AR-induced apoptosis
-
DOI 10.1093/hmg/ddl156
-
Takeshita Y., Fujinaga R., Zhao C., Yanai A., and, Shinoda K., (2006) Huntingtin-associated protein 1 (HAP1) interacts with androgen receptor (AR) and suppresses SBMA-mutant-AR-induced apoptosis. Hum. Mol. Genet. 15, 2298-2312. (Pubitemid 44288676)
-
(2006)
Human Molecular Genetics
, vol.15
, Issue.15
, pp. 2298-2312
-
-
Takeshita, Y.1
Fujinaga, R.2
Zhao, C.3
Yanai, A.4
Shinoda, K.5
-
53
-
-
67049171648
-
Neuronal protein trafficking associated with Alzheimer disease: From APP and BACE1 to glutamate receptors
-
Tang B. L., (2009) Neuronal protein trafficking associated with Alzheimer disease: from APP and BACE1 to glutamate receptors. Cell Adh. Migr. 3, 118-128.
-
(2009)
Cell Adh. Migr.
, vol.3
, pp. 118-128
-
-
Tang, B.L.1
-
54
-
-
13944276825
-
Twenty years of the Alzheimer's disease amyloid hypothesis: A genetic perspective
-
DOI 10.1016/j.cell.2005.02.008
-
Tanzi R. E., and, Bertram L., (2005) Twenty years of the Alzheimer's disease amyloid hypothesis: a genetic perspective. Cell 120, 545-555. (Pubitemid 40269768)
-
(2005)
Cell
, vol.120
, Issue.4
, pp. 545-555
-
-
Tanzi, R.E.1
Bertram, L.2
-
55
-
-
57649221135
-
Amyloid precursor protein trafficking, processing, and function
-
Thinakaran G., and, Koo E. H., (2008) Amyloid precursor protein trafficking, processing, and function. J. Biol. Chem. 283, 29615-29619.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 29615-29619
-
-
Thinakaran, G.1
Koo, E.H.2
-
56
-
-
73549083820
-
Delivery of GABAARs to synapses is mediated by HAP1-KIF5 and disrupted by mutant huntingtin
-
Twelvetrees A. E., Yuen E. Y., Arancibia-Carcamo I. L., et al. (2010) Delivery of GABAARs to synapses is mediated by HAP1-KIF5 and disrupted by mutant huntingtin. Neuron 65, 53-65.
-
(2010)
Neuron
, vol.65
, pp. 53-65
-
-
Twelvetrees, A.E.1
Yuen, E.Y.2
Arancibia-Carcamo, I.L.3
-
57
-
-
33845407472
-
GGA1 is expressed in the human brain and affects the generation of amyloid β-peptide
-
DOI 10.1523/JNEUROSCI.1982-06.2006
-
Wahle T., Thal D. R., Sastre M., Rentmeister A., Bogdanovic N., Famulok M., Heneka M. T., and, Walter J., (2006) GGA1 is expressed in the human brain and affects the generation of amyloid beta-peptide. J. Neurosci. 26, 12838-12846. (Pubitemid 44904579)
-
(2006)
Journal of Neuroscience
, vol.26
, Issue.49
, pp. 12838-12846
-
-
Wahle, T.1
Thal, D.R.2
Sastre, M.3
Rentmeister, A.4
Bogdanovic, N.5
Famulok, M.6
Heneka, M.T.7
Walter, J.8
-
58
-
-
69749090759
-
The APP-interacting protein FE65 is required for hippocampus-dependent learning and long-term potentiation
-
Wang Y., Zhang M., Moon C., Hu Q., Wang B., Martin G., Sun Z., and, Wang H., (2009) The APP-interacting protein FE65 is required for hippocampus- dependent learning and long-term potentiation. Learn. Mem. 16, 537-544.
-
(2009)
Learn. Mem.
, vol.16
, pp. 537-544
-
-
Wang, Y.1
Zhang, M.2
Moon, C.3
Hu, Q.4
Wang, B.5
Martin, G.6
Sun, Z.7
Wang, H.8
-
59
-
-
67049095945
-
Huntingtin associated protein 1 and its functions
-
Wu L. L., and, Zhou X. F., (2009) Huntingtin associated protein 1 and its functions. Cell Adh. Migr. 3, 71-76.
-
(2009)
Cell Adh. Migr.
, vol.3
, pp. 71-76
-
-
Wu, L.L.1
Zhou, X.F.2
-
60
-
-
77949317804
-
Huntingtin-associated protein-1 interacts with pro-brain-derived neurotrophic factor and mediates its transport and release
-
Wu L. L., Fan Y., Li S., Li X. J., and, Zhou X. F., (2010) Huntingtin-associated protein-1 interacts with pro-brain-derived neurotrophic factor and mediates its transport and release. J. Biol. Chem. 285, 5614-5623.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 5614-5623
-
-
Wu, L.L.1
Fan, Y.2
Li, S.3
Li, X.J.4
Zhou, X.F.5
-
61
-
-
79955507013
-
Precursor of brain-derived neurotrophic factor (proBDNF) forms a complex with huntingtin-associated protein-1 (HAP1) and sortilin that modulates proBDNF trafficking, degradation, and processing
-
Yang M., Lim Y., Li X., Zhong J. H., and, Zhou X. F., (2011) Precursor of brain-derived neurotrophic factor (proBDNF) forms a complex with huntingtin-associated protein-1 (HAP1) and sortilin that modulates proBDNF trafficking, degradation, and processing. J. Biol. Chem. 286, 16272-16284.
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 16272-16284
-
-
Yang, M.1
Lim, Y.2
Li, X.3
Zhong, J.H.4
Zhou, X.F.5
-
62
-
-
70350351389
-
Mechanism underlying activity-dependent insertion of TrkB into the neuronal surface
-
Zhao L., Sheng A. L., Huang S. H., Yin Y. X., Chen B., Li X. Z., Zhang Y., and, Chen Z. Y., (2009) Mechanism underlying activity-dependent insertion of TrkB into the neuronal surface. J. Cell Sci. 122, 3123-3136.
-
(2009)
J. Cell Sci.
, vol.122
, pp. 3123-3136
-
-
Zhao, L.1
Sheng, A.L.2
Huang, S.H.3
Yin, Y.X.4
Chen, B.5
Li, X.Z.6
Zhang, Y.7
Chen, Z.Y.8
|