Neprilysin gene expression requires binding of the amyloid precursor protein intracellular domain to its promoter: Implications for Alzheimer disease

EMBO Reports

Volumn 10, Issue 1, 2009, Pages 94-100

  Belyaev, Nikolai D ^a   Nalivaeva, Natalia N ^a   Makova, Natalia Z ^a   Turner, Anthony J ^a  

^a UNIVERSITY OF LEEDS   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; GAMMA SECRETASE INHIBITOR; HISTONE DEACETYLASE INHIBITOR; L 685458; MEMBRANE METALLOENDOPEPTIDASE; TRICHOSTATIN A; UNCLASSIFIED DRUG; VALPROIC ACID;

ALZHEIMER DISEASE; ANIMAL CELL; ARTICLE; CHROMATIN ASSEMBLY AND DISASSEMBLY; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; ENZYME ACTIVITY; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; METHYLATION; NERVE CELL; NERVE DEGENERATION; NEUROBLASTOMA CELL; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN METABOLISM; RAT;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; CELL LINE; ENZYME INHIBITORS; GENE EXPRESSION REGULATION; HISTONE DEACETYLASES; HISTONES; HUMANS; NEPRILYSIN; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; RATS;

RATTUS;

EID: 58049089518     PISSN: 1469221X     EISSN: 14693178     Source Type: Journal    
DOI: 10.1038/embor.2008.222     Document Type: Article

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