Intestinal stem cells protect their genome by selective segregation of template DNA strands

Journal of Cell Science

Volumn 115, Issue 11, 2002, Pages 2381-2388

  Potten, Christopher S ^a   Owen, Gary ^a   Booth, Dawn ^a  

^a CHRISTIE HOSPITAL   (United Kingdom)

Author keywords

DNA strand segregation; Genome protection; Intestine; Stem cells

Indexed keywords

BROXURIDINE; DNA MARKER; THYMIDINE; TRITIUM; DIAGNOSTIC AGENT;

ALTRUISM; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL AGING; CELL DIVISION; CELL LABELING; CELL LINE; CELL MATURATION; CELL PROLIFERATION; CELL STRUCTURE; CONTROLLED STUDY; DEFENSE MECHANISM; DNA DAMAGE; DNA REPAIR; DNA REPLICATION; DNA STRAND; DNA SYNTHESIS; DNA TEMPLATE; EXPERIMENTAL ANIMAL; GENE DELETION; GENE MUTATION; GENE SEGREGATION; GENOME; INTESTINE CELL; INTESTINE CRYPT; LIFESPAN; MALIGNANT TRANSFORMATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; RADIOSENSITIVITY; STEM CELL; TISSUE REGENERATION; ANIMAL; CELL TRANSFORMATION; CHROMOSOME SEGREGATION; CYTOLOGY; EPITHELIUM CELL; GAMMA RADIATION; GENETICS; INTESTINE MUCOSA; INTESTINE TUMOR; METABOLISM; MOUSE STRAIN; MUTATION; PANETH CELL; RADIATION EXPOSURE; SMALL INTESTINE;

ANIMAL; APOPTOSIS; BROMODEOXYURIDINE; CELL DIVISION; CELL TRANSFORMATION, NEOPLASTIC; CHROMOSOME SEGREGATION; DNA REPAIR; DNA REPLICATION; EPITHELIAL CELLS; GAMMA RAYS; GENOME; INTESTINAL MUCOSA; INTESTINAL NEOPLASMS; INTESTINE, SMALL; MICE; MICE, INBRED STRAINS; MUTATION; PANETH CELLS; STEM CELLS; SUPPORT, NON-U.S. GOV'T; TEMPLATES, GENETIC; ANIMALS;

EID: 0036591968     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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