Multipotent and unipotent progenitors contribute to prostate postnatal development

Nature Cell Biology

Volumn 14, Issue 11, 2012, Pages 1131-1138

  Ousset, Marielle ^a   Van Keymeulen, Alexandra ^a   Bouvencourt, Gaëlle ^a   Sharma, Neha ^a   Achouri, Younes ^b   Simons, Benjamin D ^c,d   Blanpain, Cédric ^a,e  

^a UNIVERSITÉ LIBRE DE BRUXELLES   (Belgium)

^b UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

^c UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^d UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^e WELBIO   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

ANDROGEN RECEPTOR; CYTOKERATIN 14; CYTOKERATIN 18; CYTOKERATIN 19; CYTOKERATIN 5; CYTOKERATIN 8; DOXYCYCLINE; TAMOXIFEN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR NKX3.1; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BASAL CELL; CELL DIFFERENTIATION; CELL DIVISION; CELL FATE; CELL HETEROGENEITY; CELL LINEAGE; CELL PROLIFERATION; CELL TYPE; CELLULAR HIERARCHY; CELLULAR PARAMETERS; CONTROLLED STUDY; LUMINAL CELL; MALE; MOLECULAR CLONING; MOUSE; MULTIPOTENT STEM CELL; NEUROSECRETORY CELL; NEWBORN; NONHUMAN; ORGANOGENESIS; POSTNATAL DEVELOPMENT; PRIORITY JOURNAL; PROSTATE DEVELOPMENT; PROSTATE REGENERATION; PROTEIN EXPRESSION; STEM CELL; TISSUE REGENERATION; UNIPOTENT STEM CELL;

ANIMALS; CELL DIFFERENTIATION; CELL PROLIFERATION; MALE; MICE; MULTIPOTENT STEM CELLS; PROSTATE; PROSTATIC NEOPLASMS; STEM CELLS;

MUS;

EID: 84869084046     PISSN: 14657392     EISSN: 14764679     Source Type: Journal    
DOI: 10.1038/ncb2600     Document Type: Article

References (42)

1. Timms, B.G. Prostate development: A historical perspective. Differentiation 76, 565-577 (2008 (Pubitemid 352032743)
2. Cunha, G.R. et al. The endocrinology and developmental biology of the prostate. Endocr. Rev. 8, 338-362 (1987
3. Shen, M.M. & Abate-Shen, C. Molecular genetics of prostate cancer: new prospects for old challenges. Genes Dev. 24, 1967-2000 (2010
4. Kasper, S. Exploring the origins of the normal prostate and prostate cancer stem cell. Stem Cell Rev. 4, 193-201 (2008
5. Signoretti, S. et al. p63 is a prostate basal cell marker and is required for prostate development. Am. J. Pathol. 157, 1769-1775 (2000
6. Lilja, H. & Abrahamsson, P.A. Three predominant proteins secreted by the human prostate gland. Prostate 12, 29-38 (1988
7. Peehl, D.M., Sellers, R.G. & McNeal, J.E. Keratin 19 in the adult human prostate: Tissue and cell culture studies. Cell Tissue Res. 285, 171-176 (1996 (Pubitemid 26257638)
8. Xue, Y., Smedts, F., Debruyne, F.M., de la Rosette, J.J. & Schalken, J.A. Identi-cation of intermediate cell types by keratin expression in the developing human prostate. Prostate 34, 292-301 (1998 (Pubitemid 28149874)
9. Wang, Y., Hayward, S., Cao, M., Thayer, K. & Cunha, G. Cell differentiation lineage in the prostate. Differentiation 68, 270-279 (2001 (Pubitemid 33754999)
10. Hudson, D.L. et al. Epithelial cell differentiation pathways in the human prostate: Identi-cation of intermediate phenotypes by keratin expression. J. Histochem. Cytochem. 49, 271-278 (2001 (Pubitemid 32113389)
11. Taylor, R.A., Toivanen, R. & Risbridger, G.P. Stem cells in prostate cancer: Treating the root of the problem. Endocr. Relat. Cancer 17, R273-R285 (2010
12. Marker, P.C., Donjacour, A.A., Dahiya, R. & Cunha, G.R. Hormonal, cellular, and molecular control of prostatic development. Dev. Biol. 253, 165-174 (2003 (Pubitemid 36259879)
13. Staack, A., Donjacour, A.A., Brody, J., Cunha, G.R. & Carroll, P. Mouse urogenital development: A practical approach. Differentiation 71, 402-413 (2003 (Pubitemid 37249226)
14. Blanpain, C., Horsley, V. & Fuchs, E. Epithelial stem cells: Turning over new leaves. Cell 128, 445-458 (2007 (Pubitemid 46198895)
15. Cunha, G.R. Mesenchymal-epithelial interactions: Past, present, and future. Differentiation 76, 578-586 (2008 (Pubitemid 352032745)
16. Cunha, G.R., Chung, L.W., Shannon, J.M., Taguchi, O. & Fujii, H. Hormoneinduced morphogenesis and growth: Role of mesenchymal-epithelial interactions. Recent Prog. Horm Res. 39, 559-598 (1983
17. Wu, C.T. et al. Increased prostate cell proliferation and loss of cell differentiation in mice lacking prostate epithelial androgen receptor. Proc. Natl Acad. Sci. USA 104, 12679-12684 (2007
18. Sugimura, Y., Cunha, G.R. & Donjacour, A.A. Morphogenesis of ductal networks in the mouse prostate. Biol. Reprod. 34, 961-971 (1986
19. Yang, A. et al. p63 is essential for regenerative proliferation in limb, craniofacial and epithelial development. Nature 398, 714-718 (1999 (Pubitemid 29197650)
20. Mills, A.A. et al. p63 is a p53 homologue required for limb and epidermal morphogenesis. Nature 398, 708-713 (1999 (Pubitemid 29197649)
21. Kurita, T., Medina, R.T., Mills, A.A. & Cunha, G.R. Role of p63 and basal cells in the prostate. Development 131, 4955-4964 (2004 (Pubitemid 39485353)
22. Signoretti, S. et al. p63 regulates commitment to the prostate cell lineage. Proc. Natl Acad. Sci. USA 102, 11355-11360 (2005 (Pubitemid 41153824)
23. English, H.F., Santen, R.J. & Isaacs, J.T. Response of glandular versus basal rat ventral prostatic epithelial cells to androgen withdrawal and replacement. Prostate 11, 229-242 (1987 (Pubitemid 18004762)
24. Evans, G.S. & Chandler, J.A. Cell proliferation studies in the rat prostate: II. The effects of castration and androgen-induced regeneration upon basal and secretory cell proliferation. Prostate 11, 339-351 (1987 (Pubitemid 18023662)
25. Xin, L., Lukacs, R.U., Lawson, D.A., Cheng, D. & Witte, O.N. Self-renewal and multilineage differentiation in vitro from murine prostate stem cells. Stem Cells 25, 2760-2769 (2007 (Pubitemid 350127860)
26. Goldstein, A.S. et al. Trop2 identi-es a subpopulation of murine and human prostate basal cells with stem cell characteristics. Proc. Natl Acad. Sci. USA 105, 20882-20887 (2008
27. Leong, K.G., Wang, B.E., Johnson, L. & Gao, W.Q. Generation of a prostate from a single adult stem cell. Nature 456, 804-808 (2008
28. Lawson, D.A., Xin, L., Lukacs, R.U., Cheng, D. & Witte, O.N. Isolation and functional characterization of murine prostate stem cells. Proc. Natl Acad. Sci. USA 104, 181-186 (2007 (Pubitemid 46068005)
29. Wang, X. et al. A luminal epithelial stem cell that is a cell of origin for prostate cancer. Nature 461, 495-500 (2009
30. Liu, J. et al. Regenerated luminal epithelial cells are derived from preexisting luminal epithelial cells in adult mouse prostate. Mol. Endocrinol. 25, 1849-1857 (2011
31. Choi, N., Zhang, B., Zhang, L., Ittmann, M. & Xin, L. Adult murine prostate basal and luminal cells are self-sustained lineages that can both serve as targets for prostate cancer initiation. Cancer Cell 21, 253-265 (2012
32. Van Keymeulen, A. et al. Distinct stem cells contribute to mammary gland development and maintenance. Nature 479, 189-193 (2011
33. Blackwood, J.K. et al. In situ lineage tracking of human prostatic epithelial stem cell fate reveals a common clonal origin for basal and luminal cells. J. Pathol. 225, 181-188 (2011
34. Gaisa, N.T. et al. Clonal architecture of human prostatic epithelium in benign and malignant conditions. J. Pathol. 225, 172-180 (2011
35. Goldstein, A.S., Huang, J., Guo, C., Garraway, I.P. & Witte, O.N. Identi-cation of a cell of origin for human prostate cancer. Science 329, 568-571 (2010
36. Trotman, L.C. et al. Pten dose dictates cancer progression in the prostate. PLoS Biol. 1, E59 (2003
37. Wang, S. et al. Prostate-speci-c deletion of the murine Pten tumor suppressor gene leads to metastatic prostate cancer. Cancer Cell 4, 209-221 (2003 (Pubitemid 37163835)
38. Ratnacaram, C.K. et al. Temporally controlled ablation of PTEN in adult mouse prostate epithelium generates a model of invasive prostatic adenocarcinoma. Proc. Natl Acad. Sci. USA 105, 2521-2526 (2008 (Pubitemid 351520546)
39. Srinivas, S. et al. Cre reporter strains produced by targeted insertion of EYFP and ECFP into the ROSA26 locus. BMC Dev. Biol. 1, 4-11 (2001
40. Nguyen, H., Rendl, M. & Fuchs, E. Tcf3 governs stem cell features and represses cell fate determination in skin. Cell 127, 171-183 (2006 (Pubitemid 44466637)
41. Perl, A.K., Wert, S.E., Nagy, A., Lobe, C.G. & Whitsett, J.A. Early restriction of peripheral and proximal cell lineages during formation of the lung. Proc. Natl Acad. Sci. USA 99, 10482-10487 (2002
42. Van Keymeulen, A. et al. Epidermal progenitors give rise to Merkel cells during embryonic development and adult homeostasis. J. Cell Biol. 187, 91-100 (2009