The aged niche disrupts muscle stem cell quiescence

Nature

Volumn 490, Issue 7420, 2012, Pages 355-360

  Chakkalakal, Joe V ^a   Jones, Kieran M ^b   Basson, M Albert ^b   Brack, Andrew S ^a,c,d  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b KING'S COLLEGE LONDON   (United Kingdom)

^c HARVARD STEM CELL INSTITUTE   (United States)

^d HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DOXORUBICIN; FIBROBLAST GROWTH FACTOR; FIBROBLAST GROWTH FACTOR 2; SPROUTY 1 PROTEIN; SPROUTY PROTEIN; UNCLASSIFIED DRUG;

CELL ORGANELLE; GENE EXPRESSION; MUSCLE; RODENT;

AGED; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL AGING; CELL FATE; CELL FUNCTION; CELL QUIESCENCE; CELL REGENERATION; CELL RENEWAL; CELL SUBPOPULATION; CONTROLLED STUDY; GENE OVEREXPRESSION; GROWTH INHIBITION; HOMEOSTASIS; IN VITRO STUDY; IN VIVO STUDY; MOUSE; MUSCLE; MUSCLE CELL; MUSCLE STEM CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN EXPRESSION; SATELLITE CELL; SIGNAL TRANSDUCTION; STEM CELL; STEM CELL NICHE;

AGING; ANIMALS; CELL AGING; CELL COUNT; CELL CYCLE; CELL DIFFERENTIATION; CYCLIN-DEPENDENT KINASE INHIBITOR P27; FIBROBLAST GROWTH FACTOR 2; FLOW CYTOMETRY; HOMEOSTASIS; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; MUSCLE CELLS; MUSCLE, SKELETAL; PAX7 TRANSCRIPTION FACTOR; PHOSPHOPROTEINS; SATELLITE CELLS, SKELETAL MUSCLE; SIGNAL TRANSDUCTION; STEM CELL NICHE; TIME FACTORS;

MUS;

EID: 84867676626     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature11438     Document Type: Article

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