The Lgr5 intestinal stem cell signature: Robust expression of proposed quiescent ′ +4′ cell markers

EMBO Journal

Volumn 31, Issue 14, 2012, Pages 3079-3091

  Muñoz, Javier ^a,b   Stange, Daniel E ^c   Schepers, Arnout G ^c   Van De Wetering, Marc ^c   Koo, Bon Kyoung ^c   Itzkovitz, Shalev ^d   Volckmann, Richard ^e   Kung, Kevin S ^d   Koster, Jan ^e   Radulescu, Sorina ^f   Myant, Kevin ^f   Versteeg, Rogier ^e   Sansom, Owen J ^f   Van Es, Johan H ^c   Barker, Nick ^g   Van Oudenaarden, Alexander ^c,d   Mohammed, Shabaz ^a,b   Heck, Albert J R ^a,b,h   Clevers, Hans ^c,h  

^a UTRECHT UNIVERSITY   (Netherlands)

^b NETHERLANDS PROTEOMICS CENTRE   (Netherlands)

^c UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^d MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^e UNIVERSITY OF AMSTERDAM   (Netherlands)

^f BEATSON INSTITUTE FOR CANCER RESEARCH   (United Kingdom)

^g INSTITUTE OF MEDICAL BIOLOGY   (Singapore)

^h Centre for Biomedical Genetics   (Netherlands)

Author keywords

Lgr5; proteomics; signature; stem cells; transcriptomics

Indexed keywords

CELL MARKER; MESSENGER RNA; PROTEIN LGR5; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BMI1 GENE; CELL LINEAGE; CELL POPULATION; CELL SPECIFICITY; CONTROLLED STUDY; FLUORESCENCE ACTIVATED CELL SORTING; GENE; GENE EXPRESSION; GENETIC TRANSCRIPTION; HOPX GENE; IN SITU HYBRIDIZATION; INTESTINAL STEM CELL; INTESTINE CELL; INTESTINE CRYPT; LGR5 GENE; MASS SPECTROMETRY; MICROARRAY ANALYSIS; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEOMICS; QUANTITATIVE ANALYSIS; SMOC2 GENE; STEM CELL; TERT GENE; TRANSCRIPTOMICS;

ANIMALS; ANTIGENS, DIFFERENTIATION; CALCIUM-BINDING PROTEINS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; INTESTINES; MICE; MICE, TRANSGENIC; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; RECEPTORS, G-PROTEIN-COUPLED; RNA, MESSENGER; STEM CELLS;

EID: 84864131103     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/emboj.2012.166     Document Type: Article

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