Energy functions in de novo protein design: Current challenges and future prospects

Annual Review of Biophysics

Volumn 42, Issue 1, 2013, Pages 315-335

  Li, Zhixiu ^a,b   Yang, Yuedong ^a,b   Zhan, Jian ^a,b   Dai, Liang ^a,b   Zhou, Yaoqi ^a  

^a INDIANA UNIVERSITY   (United States)

^b INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

computational assessment of designed sequences; hydrophobic patch; intrinsic disorder; secondary structure; solvent accessibility

Indexed keywords

SOLVENT;

AMINO ACID SEQUENCE; ARTICLE; CHEMICAL ANALYSIS; EGAD DESIGN; ENERGY; GENETIC ALGORITHM; HYDROPHOBICITY; LIANG GRISHIN DESIGN; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN SECONDARY STRUCTURE; PROTEIN STRUCTURE; ROSETTA DESIGN; ROSETTA DESIGN SR; SURFACE PROPERTY; X RAY CRYSTALLOGRAPHY; X RAY DIFFRACTION;

BACTERIA; COMPUTER-AIDED DESIGN; CRYSTALLOGRAPHY, X-RAY; MODELS, MOLECULAR; PROTEIN CONFORMATION; PROTEIN ENGINEERING; PROTEIN STRUCTURE, SECONDARY; PROTEINS; SOFTWARE; THERMODYNAMICS;

EID: 84877754586     PISSN: 1936122X     EISSN: 19361238     Source Type: Book Series    
DOI: 10.1146/annurev-biophys-083012-130315     Document Type: Article

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