De novo backbone and sequence design of an idealized α/β-barrel protein: Evidence of stable tertiary structure

Journal of Molecular Biology

Volumn 325, Issue 1, 2003, Pages 163-174

  Offredi, F ^a   Dubail, F ^a   Kischel, P ^a   Sarinski, K ^b   Stern, A S ^c   Van de Weerdt, C ^a   Hoch, J C ^c   Prosperi, C ^a   Francois J M ^a   Mayo, S L ^b   Martial, J A ^a  

^a UNIVERSITY OF LIÈGE   (Belgium)

^b CALIFORNIA INSTITUTE OF TECHNOLOGY   (United States)

^c HARVARD UNIVERSITY   (United States)

Author keywords

Backbone parameterization; Circular dichroism; Fluorescence; Protein design; Side chain modeling

Indexed keywords

8 ANILINO 1 NAPHTHALENESULFONIC ACID; ALPHA BETA BARREL PROTEIN; AMINO ACID; FLUORESCENT DYE; RECOMBINANT PROTEIN; TRYPTOPHAN; UNCLASSIFIED DRUG;

ALGORITHM; ALPHA HELIX; AMINO ACID SEQUENCE; AMINO ACID SYNTHESIS; ARTICLE; AUTOMATION; BETA SHEET; CIRCULAR DICHROISM; FLUORESCENCE; GEOMETRY; HYDROPHOBICITY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN CONFORMATION; PROTEIN DENATURATION; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEIN IMMOBILIZATION; PROTEIN INTERACTION; PROTEIN PURIFICATION; PROTEIN SECONDARY STRUCTURE; PROTEIN STABILITY; PROTEIN TERTIARY STRUCTURE; PROTON NUCLEAR MAGNETIC RESONANCE; SEQUENCE ANALYSIS;

EID: 0037261324     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-2836(02)01206-8     Document Type: Article

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